JP2021535226A5 - - Google Patents
Info
- Publication number
- JP2021535226A5 JP2021535226A5 JP2021536679A JP2021536679A JP2021535226A5 JP 2021535226 A5 JP2021535226 A5 JP 2021535226A5 JP 2021536679 A JP2021536679 A JP 2021536679A JP 2021536679 A JP2021536679 A JP 2021536679A JP 2021535226 A5 JP2021535226 A5 JP 2021535226A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- substituted
- lipids
- composition
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025064066A JP2025108518A (ja) | 2018-09-04 | 2025-04-09 | 核酸を臓器特異的送達するための組成物および方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862726770P | 2018-09-04 | 2018-09-04 | |
| US62/726,770 | 2018-09-04 | ||
| PCT/US2019/049552 WO2020051220A1 (en) | 2018-09-04 | 2019-09-04 | Compositions and methods for organ specific delivery of nucleic acids |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025064066A Division JP2025108518A (ja) | 2018-09-04 | 2025-04-09 | 核酸を臓器特異的送達するための組成物および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021535226A JP2021535226A (ja) | 2021-12-16 |
| JP2021535226A5 true JP2021535226A5 (enExample) | 2022-09-14 |
Family
ID=69721690
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021536679A Pending JP2021535226A (ja) | 2018-09-04 | 2019-09-04 | 核酸を臓器特異的送達するための組成物および方法 |
| JP2025064066A Pending JP2025108518A (ja) | 2018-09-04 | 2025-04-09 | 核酸を臓器特異的送達するための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025064066A Pending JP2025108518A (ja) | 2018-09-04 | 2025-04-09 | 核酸を臓器特異的送達するための組成物および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11766408B2 (enExample) |
| EP (1) | EP3846857A4 (enExample) |
| JP (2) | JP2021535226A (enExample) |
| CN (2) | CN112930198A (enExample) |
| AU (2) | AU2019335055B2 (enExample) |
| CA (1) | CA3111483A1 (enExample) |
| GB (3) | GB2592504B (enExample) |
| WO (1) | WO2020051220A1 (enExample) |
Families Citing this family (49)
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| WO2017048789A1 (en) * | 2015-09-14 | 2017-03-23 | The Board Of Regents Of The University Of Texas System | Lipocationic dendrimers and uses thereof |
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| WO2020051223A1 (en) | 2018-09-04 | 2020-03-12 | The Board Of Regents Of The University Of Texas System | Compositions and methods for organ specific delivery of nucleic acids |
| US12357580B2 (en) | 2018-06-19 | 2025-07-15 | The Board Of Regents Of The University Of Texas System | Lipid nanoparticle compositions for delivery of mRNA and long nucleic acids |
| EP3846857A4 (en) | 2018-09-04 | 2022-10-12 | The Board Of Regents Of The University Of Texas System | COMPOSITIONS AND METHODS FOR ORGAN-SPECIFIC DELIVERY OF NUCLEIC ACIDS |
| US12594347B2 (en) | 2018-09-07 | 2026-04-07 | Duke University | Nanoparticulate drug delivery systems |
| HRP20240586T1 (hr) * | 2018-10-09 | 2024-07-19 | The University Of British Columbia | Sastavi i sustavi koji sadrže transfekcijske sposobne vezikle bez organskih otapala i deterdženta i s njim povezanim postupcima |
| US20240293317A1 (en) * | 2020-04-20 | 2024-09-05 | Board Of Regents, The University Of Texas System | Lipid nanoparticle (lnp) delivery systems and uses thereof |
| EP4153560A4 (en) * | 2020-05-19 | 2024-04-24 | Ramot at Tel-Aviv University Ltd. | LIPID PARTICLES FOR NUCLEIC ACID DELIVERY AND CLINICAL APPLICATIONS THEREOF |
| KR20230122098A (ko) * | 2020-12-18 | 2023-08-22 | 오메가 테라퓨틱스, 인크. | 1,2-디올레오일-3-트리메틸암모늄-프로판(dotap) 지질나노입자에 의한 조직 특이적 핵산 전달 |
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| JP2025535237A (ja) * | 2022-10-25 | 2025-10-24 | ナノベーション・セラピューティクス・インコーポレイテッド | アンチセンスオリゴヌクレオチド送達のための脂質ナノ粒子製剤 |
| CN116236565B (zh) * | 2022-11-21 | 2025-06-27 | 成都诺恩生物科技有限公司 | 适合于肌注给药的核酸-脂质纳米颗粒、制剂及其应用 |
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| CN119119123A (zh) * | 2023-06-08 | 2024-12-13 | 西南大学 | 长春胺类衍生物及其制备方法和应用 |
| TW202525812A (zh) * | 2023-10-24 | 2025-07-01 | 南韓商綠十字股份有限公司 | 可離子化脂質及其用途 |
| US12553042B2 (en) | 2023-12-01 | 2026-02-17 | Recode Therapeutics, Inc. | Method for quantifying an amount of capped messenger RNA |
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| WO2025137646A1 (en) * | 2023-12-22 | 2025-06-26 | Recode Therapeutics, Inc. | Gene editing methods and compositions for treating cystic fibrosis |
| CN118001254B (zh) * | 2024-04-09 | 2024-07-26 | 北京悦康科创医药科技股份有限公司 | 靶向抗原呈递细胞的脂质组合物及其应用 |
| WO2025228979A1 (en) | 2024-04-30 | 2025-11-06 | Neovac Ltd. | Lipids nanoparticle formulations suitable for lung targeting |
| WO2025240356A1 (en) * | 2024-05-14 | 2025-11-20 | Recode Therapeutics, Inc. | Lipid nanoparticles for hepatic delivery |
| WO2026003403A1 (en) | 2024-06-28 | 2026-01-02 | Certest Biotec, S.L. | Ionizable lipids and lipid nanoparticles containing them for extrahepatic delivery |
| CN118750468B (zh) * | 2024-09-05 | 2025-02-18 | 北京悦康科创医药科技股份有限公司 | 一种核酸-脂质纳米颗粒冻干组合物及其制备方法和应用 |
| WO2026062291A1 (en) | 2024-09-23 | 2026-03-26 | Aldexchem Kft. | Silicon-containing spleen-targeted lnp delivery systems |
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| EP3846857A4 (en) | 2018-09-04 | 2022-10-12 | The Board Of Regents Of The University Of Texas System | COMPOSITIONS AND METHODS FOR ORGAN-SPECIFIC DELIVERY OF NUCLEIC ACIDS |
-
2019
- 2019-09-04 EP EP19858575.4A patent/EP3846857A4/en active Pending
- 2019-09-04 GB GB2104769.1A patent/GB2592504B/en active Active
- 2019-09-04 JP JP2021536679A patent/JP2021535226A/ja active Pending
- 2019-09-04 AU AU2019335055A patent/AU2019335055B2/en active Active
- 2019-09-04 WO PCT/US2019/049552 patent/WO2020051220A1/en not_active Ceased
- 2019-09-04 GB GB2111272.7A patent/GB2600800B/en active Active
- 2019-09-04 CN CN201980071318.XA patent/CN112930198A/zh active Pending
- 2019-09-04 CA CA3111483A patent/CA3111483A1/en active Pending
- 2019-09-04 CN CN202510508268.4A patent/CN120360966A/zh active Pending
- 2019-09-04 GB GB2219700.8A patent/GB2617429B/en active Active
-
2021
- 2021-03-04 US US17/191,975 patent/US11766408B2/en active Active
-
2023
- 2023-08-03 US US18/365,187 patent/US20240245618A1/en not_active Abandoned
-
2025
- 2025-04-09 JP JP2025064066A patent/JP2025108518A/ja active Pending
- 2025-08-28 AU AU2025223843A patent/AU2025223843A1/en active Pending
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