|
FR2358891A1
(fr)
|
1976-07-22 |
1978-02-17 |
Yamanouchi Pharma Co Ltd |
Composes heterocycliques contenant un azote, utilise comme agents analgesiques et anti-inflammatoires
|
|
FR2549834B1
(fr)
|
1983-07-25 |
1985-10-18 |
Sanofi Sa |
Derives de triazolo-pyrimidine, leur procede de preparation et leur application therapeutique en tant que tonicardiaques
|
|
US4921854A
(en)
|
1986-12-30 |
1990-05-01 |
Egis Gyogyszergyar |
Condensed thiazolopyrimidine, pyrimido-thiazine or thiazepine pyrimidine compounds
|
|
US5298502A
(en)
|
1988-12-12 |
1994-03-29 |
Fmc Corporation |
Method and composition for photodynamic treatment and detection of tumors
|
|
WO1994027975A1
(de)
|
1993-05-21 |
1994-12-08 |
Pentapharm Ag |
3-(mercaptoalkyl)- bzw. 3-(alkylthioalkyl)-pyrimidin-2,4 (1h, 3h)-dione
|
|
EP0912513A1
(en)
|
1996-06-28 |
1999-05-06 |
Merck & Co., Inc. |
Fibrinogen receptor antagonist prodrugs
|
|
US6339093B1
(en)
|
1999-10-08 |
2002-01-15 |
Hoffmann-La Roche Inc. |
Isoquinoline derivatives
|
|
AU2001270149A1
(en)
|
2000-06-26 |
2002-01-08 |
Merck & Co., Inc. |
Iminopyrimidine nmda nr2b receptor antagonists
|
|
US6878743B2
(en)
|
2001-09-18 |
2005-04-12 |
Sunesis Pharmaceuticals, Inc. |
Small molecule inhibitors of caspases
|
|
AR038118A1
(es)
|
2002-01-14 |
2004-12-29 |
Upjohn Co |
Compuestos derivados de la bencinamida del acido 7-oxo-4,7-dihidrotien[2,3-b[piridin-6-carboxilico 3-sustituido que son utiles como antivirales
|
|
US7005432B2
(en)
|
2002-05-16 |
2006-02-28 |
Hoffman-La Roche Inc. |
Substituted imidazol-pyridazine derivatives
|
|
KR100880972B1
(ko)
|
2004-07-13 |
2009-02-03 |
에프. 호프만-라 로슈 아게 |
설폰아마이드 유도체
|
|
TW200643015A
(en)
|
2005-03-11 |
2006-12-16 |
Akzo Nobel Nv |
2-(4-oxo-4H-quinazolin-3-yl)acetamide derivatives
|
|
US8618115B2
(en)
|
2005-10-26 |
2013-12-31 |
Bristol-Myers Squibb Company |
Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them
|
|
CA2663161C
(en)
|
2006-09-11 |
2014-10-28 |
N.V. Organon |
Quinazolinone and isoquinolinone acetamide derivatives
|
|
WO2008033757A2
(en)
|
2006-09-11 |
2008-03-20 |
N.V. Organon |
2-(1-oxo-1h-isoquinolin-2-yl) acetamide derivatives
|
|
WO2008076883A2
(en)
|
2006-12-15 |
2008-06-26 |
Abraxis Bioscience, Inc. |
Triazine derivatives and their therapeutical applications
|
|
EP1939187A1
(en)
|
2006-12-20 |
2008-07-02 |
Sanofi-Aventis |
Substituted heteroaryl pyridopyrimidone derivatives
|
|
JP2010518080A
(ja)
|
2007-02-08 |
2010-05-27 |
メルク・シャープ・エンド・ドーム・コーポレイション |
治療薬
|
|
WO2008128982A1
(en)
|
2007-04-18 |
2008-10-30 |
Probiodrug Ag |
Thioxoquinazolinone derivatives as glutaminyl cyclase inhibitors
|
|
WO2008138126A1
(en)
|
2007-05-09 |
2008-11-20 |
Neuromed Pharmaceuticals Ltd. |
Bicyclic pyrimidine derivatives as calcium channel blockers
|
|
CA2696211C
(en)
|
2007-08-21 |
2015-05-26 |
Merck Sharp & Dohme Corp. |
Heterocyclic compounds as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
|
|
TW200934497A
(en)
|
2007-11-13 |
2009-08-16 |
Organon Nv |
Heterocyclic derivatives
|
|
EA021938B1
(ru)
|
2008-05-01 |
2015-10-30 |
Сертрис Фармасьютикалз, Инк. |
Хинолины и их аналоги в качестве модуляторов сиртуина
|
|
CN102112475A
(zh)
|
2008-05-29 |
2011-06-29 |
西特里斯药业公司 |
作为沉默调节蛋白调节剂的咪唑并吡啶和相关的类似物
|
|
EP2138494A1
(en)
|
2008-06-26 |
2009-12-30 |
Sanofi-Aventis |
Substituted alkyl pyrimidin-4-one derivatives
|
|
AU2009266889B2
(en)
|
2008-07-03 |
2013-05-02 |
Glaxosmithkline Llc |
Benzimidazoles and related analogs as sirtuin modulators
|
|
CN101628913B
(zh)
|
2008-07-18 |
2013-01-23 |
中国科学院广州生物医药与健康研究院 |
用作雌激素相关受体调节剂的化合物及其应用
|
|
US9326986B2
(en)
|
2008-09-29 |
2016-05-03 |
Glaxosmithkline Llc |
Quinazolinone, quinolone and related analogs as sirtuin modulators
|
|
HUE025013T2
(hu)
|
2009-01-12 |
2016-04-28 |
Pfizer Ltd |
Szulfonamid-származékok
|
|
US8288428B2
(en)
|
2009-03-27 |
2012-10-16 |
Abbott Laboratories |
Compounds as cannabinoid receptor ligands
|
|
EP2264035A1
(en)
|
2009-06-04 |
2010-12-22 |
Merz Pharma GmbH & Co. KGaA |
Glycine B antagonists
|
|
TW201116532A
(en)
|
2009-08-05 |
2011-05-16 |
Merz Pharma Gmbh & Co Kgaa |
Metabotropic glutamate receptor modulators
|
|
EP2488520B1
(en)
|
2009-10-13 |
2015-09-02 |
Merck Sharp & Dohme B.V. |
Condensed azine-derivatives for the treatment of diseases related to the acetylcholine receptor
|
|
JP5871896B2
(ja)
|
2010-03-26 |
2016-03-01 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
B−rafキナーゼインヒビター
|
|
WO2011117382A1
(en)
|
2010-03-26 |
2011-09-29 |
Boehringer Ingelheim International Gmbh |
Pyridyltriazoles
|
|
WO2012009688A1
(en)
|
2010-07-16 |
2012-01-19 |
Rockefeller University |
Organic compounds
|
|
US9394290B2
(en)
|
2010-10-21 |
2016-07-19 |
Universitaet Des Saarlandes Campus Saarbruecken |
Selective CYP11B1 inhibitors for the treatment of cortisol dependent diseases
|
|
US20120165330A1
(en)
|
2010-12-22 |
2012-06-28 |
Sirtris Pharmaceuticals, Inc. |
Quinazolinone and related analogs as sirtuin modulators
|
|
WO2012129562A2
(en)
|
2011-03-24 |
2012-09-27 |
The Scripps Research Institute |
Compounds and methods for inducing chondrogenesis
|
|
CA2834164A1
(en)
|
2011-05-10 |
2012-11-15 |
Gilead Sciences, Inc. |
Fused benzoxazinones as ion channel modulators
|
|
EP2760830B1
(en)
|
2011-09-27 |
2016-08-03 |
Bristol-Myers Squibb Company |
Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors
|
|
US8946430B2
(en)
|
2011-09-30 |
2015-02-03 |
Bristol-Myers Squibb Company |
Quinolinone carboxamide inhibitors of endothelial lipase
|
|
EP2760839B1
(en)
|
2011-09-30 |
2015-11-25 |
Bristol-Myers Squibb Company |
Pyridinedione carboxamide inhibitors of endothelial lipase
|
|
CN102336768A
(zh)
|
2011-10-24 |
2012-02-01 |
中国科学院上海有机化学研究所 |
N’-芳亚甲基-2-(4-氧代噻吩[2,3-d]嘧啶-3-基)乙酰腙类化合物、制备方法和用途
|
|
LT2776038T
(lt)
|
2011-11-11 |
2018-04-25 |
Gilead Apollo, Llc |
Acc inhibitoriai ir jų panaudojimas
|
|
EP2812004B1
(en)
|
2012-02-10 |
2018-06-27 |
PTC Therapeutics, Inc. |
Compounds for treating spinal muscular atrophy
|
|
WO2014066743A1
(en)
|
2012-10-25 |
2014-05-01 |
Bioenergenix |
Heterocyclic compounds for the inhibition of pask
|
|
WO2014139144A1
(en)
|
2013-03-15 |
2014-09-18 |
Agios Pharmaceuticals, Inc. |
Therapeutic compounds and compositions
|
|
WO2014179144A1
(en)
|
2013-04-29 |
2014-11-06 |
E. I. Du Pont De Nemours And Company |
Fungicidal heterocyclic compounds
|
|
US9670203B2
(en)
|
2013-06-28 |
2017-06-06 |
Beigene, Ltd. |
Fused tricyclic urea compounds as Raf kinase and/or Raf kinase dimer inhibitors
|
|
WO2015007453A1
(en)
|
2013-07-15 |
2015-01-22 |
Syngenta Participations Ag |
Microbiocidal heterobicyclic derivatives
|
|
US20150141433A1
(en)
|
2013-09-26 |
2015-05-21 |
Mnemosyne Pharmaceuticals, Inc. |
N-arylmethyl sulfonamide negative modulators of nr2a
|
|
MX2016004540A
(es)
|
2013-10-11 |
2016-07-21 |
Hoffmann La Roche |
Tiazolopirimidinonas como moduladores de la actividad de receptores de n-metil-d-aspartato (nmda).
|
|
WO2015064714A1
(ja)
|
2013-10-31 |
2015-05-07 |
国立大学法人東京大学 |
オートタキシン阻害活性を有する1-置換イミダゾピリミジノン誘導体
|
|
CN103664877A
(zh)
|
2013-12-25 |
2014-03-26 |
重庆医药工业研究院有限责任公司 |
一种喹啉衍生物、其制备方法和应用
|
|
US9617226B2
(en)
|
2014-09-05 |
2017-04-11 |
AbbVie Deutschland GmbH & Co. KG |
Fused heterocyclic or carbocyclic compounds carrying a substituted cycloaliphatic radical and use thereof for treating vasopressin-related diseases
|
|
US12006328B2
(en)
|
2014-11-18 |
2024-06-11 |
Emory University |
Thieno[2,3-d]pyrimidin-4-one derivatives as NMDAR modulators and uses related thereto
|
|
EP3283487B1
(en)
|
2015-04-15 |
2019-10-16 |
H. Hoffnabb-La Roche Ag |
Pyridopyrimidinones and their use as nmda receptor modulators
|
|
JP2018530593A
(ja)
|
2015-10-16 |
2018-10-18 |
ノースウェスタン ユニバーシティ |
統合失調症、双極性障害、認知障害及び大うつ病性障害の治療のための非定型的抗精神病薬ならびにnmda調節剤の医薬品の組み合わせ
|
|
SMT202000534T1
(it)
|
2015-12-09 |
2020-11-10 |
Cadent Therapeutics Inc |
Modulatori eteroaromatici del recettore nmda e loro usi
|
|
EP4006038A1
(en)
|
2015-12-09 |
2022-06-01 |
Cadent Therapeutics, Inc. |
Thienopyrimidinone nmda receptor modulators and uses thereof
|
|
US20170305861A1
(en)
|
2016-04-25 |
2017-10-26 |
Immunomet Therapeutics, Inc |
Heteroaryl compounds comprising nitrogen and use thereof
|
|
US11186564B2
(en)
|
2016-08-04 |
2021-11-30 |
Sunovion Pharmaceuticals Inc. |
Dual NAV1.2/5HT2a inhibitors for treating CNS disorders
|
|
ES2975336T3
(es)
|
2016-12-22 |
2024-07-04 |
Novartis Ag |
Moduladores del receptor NMDA y usos de los mismos
|
|
SI3687996T1
(sl)
|
2017-09-27 |
2022-04-29 |
Incyte Corporation |
Soli pirolotriazinskih derivatov, ki so uporabne kot zaviralci TAM
|
|
BR112021001967A2
(pt)
|
2018-08-03 |
2021-04-27 |
Cadent Therapeutics, Inc. |
moduladores de receptor nmda heteroaromáticos e usos dos mesmos
|
|
US11554120B2
(en)
|
2018-08-03 |
2023-01-17 |
Bristol-Myers Squibb Company |
1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists and methods and uses therefor
|