JP2021531022A5 - - Google Patents

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Publication number
JP2021531022A5
JP2021531022A5 JP2021504230A JP2021504230A JP2021531022A5 JP 2021531022 A5 JP2021531022 A5 JP 2021531022A5 JP 2021504230 A JP2021504230 A JP 2021504230A JP 2021504230 A JP2021504230 A JP 2021504230A JP 2021531022 A5 JP2021531022 A5 JP 2021531022A5
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JP
Japan
Prior art keywords
target
cyclic
polyribonucleotide
composition according
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2021504230A
Other languages
English (en)
Japanese (ja)
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JP2021531022A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/043272 external-priority patent/WO2020023655A1/en
Publication of JP2021531022A publication Critical patent/JP2021531022A/ja
Publication of JP2021531022A5 publication Critical patent/JP2021531022A5/ja
Priority to JP2024159028A priority Critical patent/JP2024169484A/ja
Withdrawn legal-status Critical Current

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JP2021504230A 2018-07-24 2019-07-24 環状ポリリボヌクレオチドを含む組成物及びその使用 Withdrawn JP2021531022A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024159028A JP2024169484A (ja) 2018-07-24 2024-09-13 環状ポリリボヌクレオチドを含む組成物及びその使用

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862702714P 2018-07-24 2018-07-24
US62/702,714 2018-07-24
US201962823569P 2019-03-25 2019-03-25
US62/823,569 2019-03-25
US201962863670P 2019-06-19 2019-06-19
US62/863,670 2019-06-19
PCT/US2019/043272 WO2020023655A1 (en) 2018-07-24 2019-07-24 Compositions comprising circular polyribonucleotides and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024159028A Division JP2024169484A (ja) 2018-07-24 2024-09-13 環状ポリリボヌクレオチドを含む組成物及びその使用

Publications (2)

Publication Number Publication Date
JP2021531022A JP2021531022A (ja) 2021-11-18
JP2021531022A5 true JP2021531022A5 (https=) 2022-08-02

Family

ID=69182387

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021504230A Withdrawn JP2021531022A (ja) 2018-07-24 2019-07-24 環状ポリリボヌクレオチドを含む組成物及びその使用
JP2024159028A Pending JP2024169484A (ja) 2018-07-24 2024-09-13 環状ポリリボヌクレオチドを含む組成物及びその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024159028A Pending JP2024169484A (ja) 2018-07-24 2024-09-13 環状ポリリボヌクレオチドを含む組成物及びその使用

Country Status (12)

Country Link
US (1) US20210292761A1 (https=)
EP (1) EP3827084A4 (https=)
JP (2) JP2021531022A (https=)
KR (1) KR102950624B1 (https=)
CN (1) CN112567038A (https=)
AU (2) AU2019312269A1 (https=)
BR (1) BR112021001343A2 (https=)
CA (1) CA3107683A1 (https=)
IL (1) IL280354A (https=)
MX (1) MX2021000965A (https=)
SG (1) SG11202100750XA (https=)
WO (1) WO2020023655A1 (https=)

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WO2017222911A1 (en) 2016-06-20 2017-12-28 The Board Of Trustees Of The Leland Stanford Junior University Circular rnas and their use in immunomodulation
CN110612353A (zh) 2017-03-03 2019-12-24 加利福尼亚大学董事会 经由抑制性tRNAs和脱氨酶对突变进行RNA靶向
CN111819185A (zh) 2017-12-15 2020-10-23 旗舰创业创新第六有限责任公司 包含环状多核糖核苷酸的组合物及其用途
WO2020198403A2 (en) * 2019-03-25 2020-10-01 Flagship Pioneering Innovations Vi, Llc Compositions comprising modified circular polyribonucleotides and uses thereof
US20220288176A1 (en) * 2019-08-28 2022-09-15 The Board Of Trustees Of The Leland Stanford Junior University Circular rna modification and methods of use
AU2020395113A1 (en) 2019-12-02 2022-06-09 Shape Therapeutics Inc. Therapeutic editing
CN115361954A (zh) 2020-01-29 2022-11-18 旗舰创业创新第六有限责任公司 用于翻译的组合物及其使用方法
CN111500681A (zh) * 2020-03-20 2020-08-07 青岛大学 用于检测piRNA与mRNA结合的可视化方法及其应用
US20230203192A1 (en) * 2020-05-20 2023-06-29 Flagship Pioneering, Inc. Compositions and methods for producing human polyclonal antibodies
KR20230028375A (ko) 2020-06-25 2023-02-28 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 원형 rna 번역을 구동하는 유전 요소와 이를 사용하는 방법
AU2021300378A1 (en) * 2020-07-01 2023-01-19 Elevatebio Technologies, Inc. Compositions and methods for cellular reprogramming using circular RNA
CN113249811B (zh) * 2021-05-13 2022-11-08 太原理工大学 一种中空纳米纤维内部固定化生物酶的制备方法
US20240240218A1 (en) 2021-05-18 2024-07-18 Flagship Pioneering Innovations Vi, Llc Methods of enriching for circular polyribonucleotides
US20240240219A1 (en) 2021-05-18 2024-07-18 Flagship Pioneering Innovations Vi, Llc Methods of enriching for circular polyribonucleotides
AU2022285744A1 (en) * 2021-06-02 2023-12-14 Beam Therapeutics Inc. Circular guide rnas for crispr/cas editing systems
CA3219570A1 (en) * 2021-06-25 2022-12-29 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for improved protein translation from recombinant circular rnas
CN113264842B (zh) 2021-07-21 2022-03-01 苏州科锐迈德生物医药科技有限公司 一种脂质化合物及包含其的脂质载体、核酸脂质纳米粒组合物和药物制剂
US20250002898A1 (en) 2021-07-27 2025-01-02 Flagship Pioneering Innovations Vi, Llc Devices, systems and methods for processing
CN114591986A (zh) * 2021-07-29 2022-06-07 苏州科锐迈德生物医药科技有限公司 环状rna分子及其在目标蛋白的靶向降解中的应用
MX2024003262A (es) 2021-09-17 2024-06-19 Flagship Pioneering Innovations Vi Llc Composiciones y metodos para producir poliribonucleotidos circulares.
CN116103284B (zh) * 2021-11-09 2025-09-23 中国科学院天津工业生物技术研究所 环形gRNA及其相关生物材料与应用
KR20240118174A (ko) 2021-12-17 2024-08-02 플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 변성 조건 하에서의 원형 rna의 풍부화를 위한 방법
CN121057577A (zh) 2023-01-27 2025-12-02 赛欧生物医药股份有限公司 经修饰的脂质组合物及其用途
WO2025127854A1 (ko) * 2023-12-14 2025-06-19 한국과학기술원 Circular rna를 이용한 표적 mrna 발현 저해

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AUPR604101A0 (en) * 2001-06-29 2001-07-26 Unisearch Limited Aptamers
AU2006275579B2 (en) * 2005-08-01 2012-10-04 Purdue Research Foundation Multivalent RNA nanoparticles for delivery of active agents to a cell
US20110065086A1 (en) 2008-02-21 2011-03-17 Otc Biotechnologies, Llc Methods of producing homogeneous plastic-adherent aptamer-magnetic bead-fluorophore and other sandwich assays
AU2013266968B2 (en) * 2012-05-25 2017-06-29 Emmanuelle CHARPENTIER Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription
CN120574876A (zh) 2013-08-22 2025-09-02 纳幕尔杜邦公司 使用向导rna/cas内切核酸酶系统的植物基因组修饰及其使用方法
JP7106461B2 (ja) * 2016-06-07 2022-07-26 セファイド 熱安定性ポリメラーゼ阻害剤組成物及び方法
WO2020257730A1 (en) * 2019-06-19 2020-12-24 Flagship Pioneering Innovations Vi, Llc Compositions comprising circular polyribonucleotides for protein modulation and uses thereof

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