JP2021531022A5 - - Google Patents
Info
- Publication number
- JP2021531022A5 JP2021531022A5 JP2021504230A JP2021504230A JP2021531022A5 JP 2021531022 A5 JP2021531022 A5 JP 2021531022A5 JP 2021504230 A JP2021504230 A JP 2021504230A JP 2021504230 A JP2021504230 A JP 2021504230A JP 2021531022 A5 JP2021531022 A5 JP 2021531022A5
- Authority
- JP
- Japan
- Prior art keywords
- target
- cyclic
- polyribonucleotide
- composition according
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024159028A JP2024169484A (ja) | 2018-07-24 | 2024-09-13 | 環状ポリリボヌクレオチドを含む組成物及びその使用 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862702714P | 2018-07-24 | 2018-07-24 | |
| US62/702,714 | 2018-07-24 | ||
| US201962823569P | 2019-03-25 | 2019-03-25 | |
| US62/823,569 | 2019-03-25 | ||
| US201962863670P | 2019-06-19 | 2019-06-19 | |
| US62/863,670 | 2019-06-19 | ||
| PCT/US2019/043272 WO2020023655A1 (en) | 2018-07-24 | 2019-07-24 | Compositions comprising circular polyribonucleotides and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024159028A Division JP2024169484A (ja) | 2018-07-24 | 2024-09-13 | 環状ポリリボヌクレオチドを含む組成物及びその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021531022A JP2021531022A (ja) | 2021-11-18 |
| JP2021531022A5 true JP2021531022A5 (enExample) | 2022-08-02 |
Family
ID=69182387
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021504230A Withdrawn JP2021531022A (ja) | 2018-07-24 | 2019-07-24 | 環状ポリリボヌクレオチドを含む組成物及びその使用 |
| JP2024159028A Pending JP2024169484A (ja) | 2018-07-24 | 2024-09-13 | 環状ポリリボヌクレオチドを含む組成物及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024159028A Pending JP2024169484A (ja) | 2018-07-24 | 2024-09-13 | 環状ポリリボヌクレオチドを含む組成物及びその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20210292761A1 (enExample) |
| EP (1) | EP3827084A4 (enExample) |
| JP (2) | JP2021531022A (enExample) |
| KR (1) | KR102950624B1 (enExample) |
| CN (2) | CN122146706A (enExample) |
| AU (2) | AU2019312269A1 (enExample) |
| BR (1) | BR112021001343A2 (enExample) |
| CA (1) | CA3107683A1 (enExample) |
| IL (1) | IL280354A (enExample) |
| MX (1) | MX2021000965A (enExample) |
| SG (1) | SG11202100750XA (enExample) |
| WO (1) | WO2020023655A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017222911A1 (en) | 2016-06-20 | 2017-12-28 | The Board Of Trustees Of The Leland Stanford Junior University | Circular rnas and their use in immunomodulation |
| CN110612353A (zh) | 2017-03-03 | 2019-12-24 | 加利福尼亚大学董事会 | 经由抑制性tRNAs和脱氨酶对突变进行RNA靶向 |
| MX2020006150A (es) | 2017-12-15 | 2020-11-11 | Flagship Pioneering Innovations Vi Llc | Composiciones que comprenden polirribonucleotidos circulares y usos de las mismas. |
| JP7618577B2 (ja) | 2019-03-25 | 2025-01-21 | フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー | 修飾環状ポリリボヌクレオチドを含む組成物及びその使用 |
| US12636369B2 (en) | 2019-06-19 | 2026-05-26 | Flagship Pioneering Innovations Vi, Llc | Compositions comprising circular polyribonucleotides for protein modulation and uses thereof |
| US20220288176A1 (en) * | 2019-08-28 | 2022-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Circular rna modification and methods of use |
| US11827880B2 (en) | 2019-12-02 | 2023-11-28 | Shape Therapeutics Inc. | Therapeutic editing |
| TW202142689A (zh) | 2020-01-29 | 2021-11-16 | 美商旗艦先鋒創新有限責任公司 | 用於轉譯之組合物及其使用方法 |
| CN111500681A (zh) * | 2020-03-20 | 2020-08-07 | 青岛大学 | 用于检测piRNA与mRNA结合的可视化方法及其应用 |
| WO2021236952A1 (en) * | 2020-05-20 | 2021-11-25 | Flagship Pioneering, Inc. | Compositions and methods for producing human polyclonal antibodies |
| KR20230028375A (ko) | 2020-06-25 | 2023-02-28 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 원형 rna 번역을 구동하는 유전 요소와 이를 사용하는 방법 |
| CN116194581A (zh) * | 2020-07-01 | 2023-05-30 | 艾勒维生技公司 | 使用环状rna进行细胞重编程的组合物和方法 |
| CN113249811B (zh) * | 2021-05-13 | 2022-11-08 | 太原理工大学 | 一种中空纳米纤维内部固定化生物酶的制备方法 |
| JP2024521304A (ja) | 2021-05-18 | 2024-05-31 | フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー | 環状ポリリボヌクレオチドを濃縮する方法 |
| EP4341423A1 (en) | 2021-05-18 | 2024-03-27 | Flagship Pioneering Innovations VI, LLC | Methods of enriching for circular polyribonucleotides |
| AU2022285744A1 (en) * | 2021-06-02 | 2023-12-14 | Beam Therapeutics Inc. | Circular guide rnas for crispr/cas editing systems |
| JP2024528469A (ja) * | 2021-06-25 | 2024-07-30 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 組換え環状ｒｎａからの改良されたタンパク質翻訳のための組成物及び方法 |
| CN113264842B (zh) | 2021-07-21 | 2022-03-01 | 苏州科锐迈德生物医药科技有限公司 | 一种脂质化合物及包含其的脂质载体、核酸脂质纳米粒组合物和药物制剂 |
| KR20240047986A (ko) | 2021-07-27 | 2024-04-12 | 플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 | 가공을 위한 디바이스, 시스템 및 방법 |
| CN114591986A (zh) * | 2021-07-29 | 2022-06-07 | 苏州科锐迈德生物医药科技有限公司 | 环状rna分子及其在目标蛋白的靶向降解中的应用 |
| AR127073A1 (es) | 2021-09-17 | 2023-12-13 | Flagship Pioneering Innovations Vi Llc | Composiciones y métodos para producir polirribonucleótidos circulares |
| CN116103284B (zh) * | 2021-11-09 | 2025-09-23 | 中国科学院天津工业生物技术研究所 | 环形gRNA及其相关生物材料与应用 |
| CN118510896A (zh) | 2021-12-17 | 2024-08-16 | 旗舰创业创新六公司 | 用于在变性条件下富集环状rna的方法 |
| JP2026503676A (ja) | 2023-01-27 | 2026-01-29 | セイル バイオメディシンズ インコーポレイテッド | 修飾脂質組成物およびその使用 |
| KR102968720B1 (ko) * | 2023-12-14 | 2026-05-26 | 한국과학기술원 | Circular RNA를 이용한 표적 mRNA 발현 저해 |
| WO2026096919A1 (en) | 2024-11-01 | 2026-05-07 | Sail Biomedicines, Inc. | Novel dipepetide core lipids, lipid carriers, and methods of using thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPR604101A0 (en) * | 2001-06-29 | 2001-07-26 | Unisearch Limited | Aptamers |
| US20100003753A1 (en) * | 2005-08-01 | 2010-01-07 | Purdue Research Foundation | Multivalent rna nanoparticles for delivery of active agents to a cell |
| US20110065086A1 (en) | 2008-02-21 | 2011-03-17 | Otc Biotechnologies, Llc | Methods of producing homogeneous plastic-adherent aptamer-magnetic bead-fluorophore and other sandwich assays |
| ES2728782T3 (es) * | 2012-05-25 | 2019-10-28 | Univ California | Métodos y composiciones para la modificación de ADN objetivo dirigida por ARN y para la modulación de la transcripción dirigida por ARN |
| CN106133138A (zh) | 2013-08-22 | 2016-11-16 | 先锋国际良种公司 | 使用引导多核苷酸/cas内切核酸酶系统的基因组修饰及其使用方法 |
| EP3464596B1 (en) * | 2016-06-07 | 2025-07-30 | Cepheid | Thermostable polymerase inhibitor compositions and methods |
| US12636369B2 (en) * | 2019-06-19 | 2026-05-26 | Flagship Pioneering Innovations Vi, Llc | Compositions comprising circular polyribonucleotides for protein modulation and uses thereof |
-
2019
- 2019-07-24 KR KR1020217005234A patent/KR102950624B1/ko active Active
- 2019-07-24 US US17/262,591 patent/US20210292761A1/en active Pending
- 2019-07-24 JP JP2021504230A patent/JP2021531022A/ja not_active Withdrawn
- 2019-07-24 WO PCT/US2019/043272 patent/WO2020023655A1/en not_active Ceased
- 2019-07-24 CN CN202511971333.3A patent/CN122146706A/zh active Pending
- 2019-07-24 EP EP19840286.9A patent/EP3827084A4/en active Pending
- 2019-07-24 MX MX2021000965A patent/MX2021000965A/es unknown
- 2019-07-24 AU AU2019312269A patent/AU2019312269A1/en not_active Abandoned
- 2019-07-24 SG SG11202100750XA patent/SG11202100750XA/en unknown
- 2019-07-24 BR BR112021001343-1A patent/BR112021001343A2/pt unknown
- 2019-07-24 CA CA3107683A patent/CA3107683A1/en active Pending
- 2019-07-24 CN CN201980051856.2A patent/CN112567038A/zh active Pending
-
2021
- 2021-01-24 IL IL280354A patent/IL280354A/en unknown
-
2024
- 2024-09-13 JP JP2024159028A patent/JP2024169484A/ja active Pending
-
2026
- 2026-02-19 AU AU2026201251A patent/AU2026201251A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109843902B (zh) | 用于B型肝炎病毒感染的RNAi剂 | |
| US20210292761A1 (en) | Compositions comprising circular polyribonucleotides and uses thereof | |
| US20230104113A1 (en) | Delivery of compositions comprising circular polyribonucleotides | |
| CN105658797A (zh) | 用于调节rna的组合物和方法 | |
| JP2009528346A5 (enExample) | ||
| JP2012521358A5 (enExample) | ||
| JP2022536951A (ja) | 環状ポリリボヌクレオチドを投与する方法 | |
| KR20200013083A (ko) | 짧은 간섭 핵산 （ｓｉＮＡ）을 사용한 Ｂ형 간염 바이러스 （ＨＢＶ） 유전자 발현의 ＲＮＡ 간섭 매개 억제 | |
| CN105899663B (zh) | 用于基因表达控制的人工模拟miRNA及其用途 | |
| JP2014533953A (ja) | 治療用ｒｎａスイッチ組成物及び使用方法 | |
| CN113249380B (zh) | 靶向covid-19新冠病毒的反义寡核苷酸、natac嵌合分子及其应用 | |
| CN112941072B (zh) | 一种核酸自组装结构及其制备方法和应用 | |
| CN105073141A (zh) | 用于将基因递送到细胞的功能化dna树状聚合物 | |
| CN112996913A (zh) | 寡聚核酸分子及其应用 | |
| JP5606318B2 (ja) | トランスフェクション剤 | |
| Suryawanshi et al. | A simple alternative to stereotactic injection for brain specific knockdown of miRNA | |
| ES2368298A1 (es) | Método para la administración de oligonucleótidos. | |
| WO2025223537A1 (zh) | 一种dsRNA、其应用及制备方法 | |
| JP2020513849A5 (enExample) | ||
| TWI414301B (zh) | 以微核醣核酸miＲ－１４１為標的治療小核醣核酸病毒感染 | |
| WO2025002247A1 (zh) | 靶向人血管生成素样蛋白3的核酸及其用途 | |
| CN111154755B (zh) | 一种双链寡核苷酸dna及其应用 | |
| CN102140471B (zh) | 一种抑制肿瘤生长的寡聚核酸及其应用 | |
| CN116159145A (zh) | 含七叶皂苷和/或其盐化合物的转染复合物在促转染的应用 | |
| JP7095910B2 (ja) | インスリン抵抗性を検出し治療するための組成物および方法 |