JP2021524730A5 - - Google Patents

Info

Publication number
JP2021524730A5
JP2021524730A5 JP2020545683A JP2020545683A JP2021524730A5 JP 2021524730 A5 JP2021524730 A5 JP 2021524730A5 JP 2020545683 A JP2020545683 A JP 2020545683A JP 2020545683 A JP2020545683 A JP 2020545683A JP 2021524730 A5 JP2021524730 A5 JP 2021524730A5
Authority
JP
Japan
Prior art keywords
seq
oligonucleotide
composition according
nucleic acid
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020545683A
Other languages
English (en)
Japanese (ja)
Other versions
JP7532257B2 (ja
JP2021524730A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/NL2019/050131 external-priority patent/WO2019168402A1/en
Publication of JP2021524730A publication Critical patent/JP2021524730A/ja
Publication of JP2021524730A5 publication Critical patent/JP2021524730A5/ja
Priority to JP2024123185A priority Critical patent/JP2024156786A/ja
Application granted granted Critical
Publication of JP7532257B2 publication Critical patent/JP7532257B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020545683A 2018-03-02 2019-03-01 ポリオーマウイルス複製の阻害 Active JP7532257B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024123185A JP2024156786A (ja) 2018-03-02 2024-07-30 ポリオーマウイルス複製の阻害

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18159797.2 2018-03-02
EP18159797 2018-03-02
PCT/NL2019/050131 WO2019168402A1 (en) 2018-03-02 2019-03-01 Inhibition of polyomavirus replication

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024123185A Division JP2024156786A (ja) 2018-03-02 2024-07-30 ポリオーマウイルス複製の阻害

Publications (3)

Publication Number Publication Date
JP2021524730A JP2021524730A (ja) 2021-09-16
JP2021524730A5 true JP2021524730A5 (enExample) 2022-02-16
JP7532257B2 JP7532257B2 (ja) 2024-08-13

Family

ID=61563209

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020545683A Active JP7532257B2 (ja) 2018-03-02 2019-03-01 ポリオーマウイルス複製の阻害
JP2024123185A Pending JP2024156786A (ja) 2018-03-02 2024-07-30 ポリオーマウイルス複製の阻害

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024123185A Pending JP2024156786A (ja) 2018-03-02 2024-07-30 ポリオーマウイルス複製の阻害

Country Status (7)

Country Link
US (2) US11661602B2 (enExample)
EP (1) EP3759221A1 (enExample)
JP (2) JP7532257B2 (enExample)
CN (2) CN112218949B (enExample)
BR (1) BR112020017949A2 (enExample)
CA (1) CA3092817A1 (enExample)
WO (1) WO2019168402A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019168402A1 (en) * 2018-03-02 2019-09-06 Academisch Ziekenhuis Leiden H.O.D.N. Lumc Inhibition of polyomavirus replication
IL316802A (en) * 2022-05-06 2025-01-01 Academisch Ziekenhuis Leiden Oligonucleotide

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7339051B2 (en) * 2003-04-28 2008-03-04 Isis Pharmaceuticals, Inc. Compositions and methods for the treatment of severe acute respiratory syndrome (SARS)
US20050118625A1 (en) * 2003-10-02 2005-06-02 Mounts William M. Nucleic acid arrays for detecting gene expression associated with human osteoarthritis and human proteases
JP2007536937A (ja) * 2004-05-12 2007-12-20 カメル・カリーリ 霊長類ポリオーマウイルス遺伝子のsiRNA干渉用組成物および方法
US7892795B2 (en) * 2005-08-02 2011-02-22 Focus Diagnostics, Inc. Methods and compositions for detecting BK virus
WO2007127919A2 (en) * 2006-04-28 2007-11-08 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting expression of a gene from the jc virus
EP1857548A1 (en) * 2006-05-19 2007-11-21 Academisch Ziekenhuis Leiden Means and method for inducing exon-skipping
WO2008077511A1 (en) * 2006-12-22 2008-07-03 Karolinska Institutet Innovations Ab Human polyomavirus and methods of diagnosis and treatment
US20110118340A1 (en) * 2008-02-08 2011-05-19 Muthiah Manoharan Delivery of rnai constructs to oligodendrocytes
US20090246754A1 (en) * 2008-02-19 2009-10-01 Intelligent Mdx Optimized probes and primers and methods of using same for the detection and quantitation of bk virus
WO2012143427A1 (en) 2011-04-19 2012-10-26 Santaris Pharma A/S Anti polyomavirus compounds
CN102363818B (zh) * 2011-06-28 2013-01-02 同昕生物技术(北京)有限公司 同时检测人ebv、bkv和 cmv的三重实时荧光定量pcr方法及试剂盒
WO2013119979A1 (en) 2012-02-08 2013-08-15 Isis Pharmaceuticals, Inc. Methods and compositions for modulating factor vii expression
CN103276107B (zh) * 2013-05-13 2014-11-19 中国医学科学院病原生物学研究所 一种高灵敏度检测和鉴定人多瘤病毒的方法
EP3047023B1 (en) 2013-09-19 2019-09-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions and methods for inhibiting jc virus (jcv)
AU2016366229A1 (en) * 2015-12-09 2018-05-17 Excision Biotherapeutics, Inc. Gene editing methods and compositions for eliminating risk of JC virus activation and PML (progressive multifocal leukoencephalopathy) during immunosuppresive therapy
ES2903394T3 (es) * 2015-12-14 2022-04-01 Cold Spring Harbor Laboratory Composiciones para el tratamiento de la retinitis pigmentosa 13
US11096956B2 (en) * 2015-12-14 2021-08-24 Stoke Therapeutics, Inc. Antisense oligomers and uses thereof
WO2019168402A1 (en) * 2018-03-02 2019-09-06 Academisch Ziekenhuis Leiden H.O.D.N. Lumc Inhibition of polyomavirus replication

Similar Documents

Publication Publication Date Title
JP5875976B2 (ja) 多価rna干渉のためのポリヌクレオチド、組成物およびそれらの使用方法
US20080293142A1 (en) Multiple shRNA Expression Vectors and Methods of Construction
CA2976601C (en) Oligonucleotide therapy for leber congenital amaurosis
JP6932698B2 (ja) アルファ1アンチトリプシン欠乏症の治療のための材料および方法
KR101237036B1 (ko) 안티센스 가닥에 의한 오프-타겟 효과를 최소화한 신규한 siRNA 구조 및 그 용도
JP2017537626A5 (enExample)
JP2009536827A5 (enExample)
RU2015133046A (ru) Двойной вектор для подавления вируса иммунодефицита человека
AU2016344609A1 (en) Materials and methods for treatment of duchenne muscular dystrophy
AU2025205365A1 (en) Structure of oncolytic virus comprising bispecific nucleic acid molecule
CN110214149B (zh) 用于治疗疼痛相关病症的材料和方法
JP2012503493A5 (enExample)
JP2024107295A5 (enExample)
US20200024601A1 (en) Antisense oligonucleotides to treat dystrophic epidermoylsis bullosa
JP2021524730A5 (enExample)
JP2023503635A (ja) Rna分子を合成する方法
EP3538671A1 (en) Therapeutic oligonucleotides capture and detection
JP5671791B2 (ja) 近位尿細管上皮細胞(rptec)の培養方法
CA2627443C (en) Dna constructs for specific inhibition of gene expression by rna interference
CN102533742B (zh) 一种双链核苷酸序列、含其的重组质粒及其构建方法
JP2006500017A (ja) RNA発現のためのアデノウイルスのVA1PolIII発現システム
KR20230121569A (ko) 상동지정복구를 위한 TaRGET 시스템 및 이를 이용한 유전자 편집 방법
Lupták et al. Mammalian self-cleaving ribozymes
EP4519434A1 (en) Ribozymes
CN105483156A (zh) Bac-to-Bac杆状病毒表达系统在制备家蚕microRNA超量表达系统中的应用