JP2021520393A5 - - Google Patents

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Publication number
JP2021520393A5
JP2021520393A5 JP2020554864A JP2020554864A JP2021520393A5 JP 2021520393 A5 JP2021520393 A5 JP 2021520393A5 JP 2020554864 A JP2020554864 A JP 2020554864A JP 2020554864 A JP2020554864 A JP 2020554864A JP 2021520393 A5 JP2021520393 A5 JP 2021520393A5
Authority
JP
Japan
Prior art keywords
antibody
fragment
seq
amino acid
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020554864A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021520393A (ja
JP7437317B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/025363 external-priority patent/WO2019195273A1/en
Publication of JP2021520393A publication Critical patent/JP2021520393A/ja
Publication of JP2021520393A5 publication Critical patent/JP2021520393A5/ja
Priority to JP2024018521A priority Critical patent/JP7829605B2/ja
Application granted granted Critical
Publication of JP7437317B2 publication Critical patent/JP7437317B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020554864A 2018-04-02 2019-04-02 コネキシン43抗体およびその使用 Active JP7437317B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024018521A JP7829605B2 (ja) 2018-04-02 2024-02-09 コネキシン43抗体およびその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862651668P 2018-04-02 2018-04-02
US62/651,668 2018-04-02
PCT/US2019/025363 WO2019195273A1 (en) 2018-04-02 2019-04-02 Connexin 43 antibodies and use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024018521A Division JP7829605B2 (ja) 2018-04-02 2024-02-09 コネキシン43抗体およびその使用

Publications (3)

Publication Number Publication Date
JP2021520393A JP2021520393A (ja) 2021-08-19
JP2021520393A5 true JP2021520393A5 (enExample) 2022-04-11
JP7437317B2 JP7437317B2 (ja) 2024-02-22

Family

ID=68101187

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020554864A Active JP7437317B2 (ja) 2018-04-02 2019-04-02 コネキシン43抗体およびその使用
JP2024018521A Active JP7829605B2 (ja) 2018-04-02 2024-02-09 コネキシン43抗体およびその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024018521A Active JP7829605B2 (ja) 2018-04-02 2024-02-09 コネキシン43抗体およびその使用

Country Status (6)

Country Link
US (2) US12227561B2 (enExample)
JP (2) JP7437317B2 (enExample)
CN (2) CN116854816A (enExample)
AU (1) AU2019249427B2 (enExample)
CA (1) CA3095897A1 (enExample)
WO (1) WO2019195273A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12227561B2 (en) 2018-04-02 2025-02-18 Alamab Therapeutics, Inc. Connexin 43 antibodies and use thereof
IL285369B2 (en) * 2019-02-04 2025-10-01 Alamab Therapeutics Inc Connexin 43 antibodies and their use
US20220162298A1 (en) * 2019-02-28 2022-05-26 Board Of Regents, The University Of Texas System Compositions for treating osteosarcoma and methods of use
AU2020358101A1 (en) * 2019-10-02 2022-04-28 Alamab Therapeutics, Inc. Anto-connexin antibody formulations
CN113307871B (zh) * 2020-02-27 2023-05-02 福州拓新天成生物科技有限公司 新型抗cd19抗体和cd19-car-t细胞的制备及其应用
JP2023537316A (ja) * 2020-07-31 2023-08-31 アラマブ セラピューティクス, インコーポレイテッド 抗コネキシン抗体製剤
WO2024243439A2 (en) * 2023-05-24 2024-11-28 Alamab Therapeutics, Inc. Method of treating bone cancers
US12571255B2 (en) 2023-06-02 2026-03-10 Universal Electronics Inc. Systems and method for controlling window treatments

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US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4740461A (en) 1983-12-27 1988-04-26 Genetics Institute, Inc. Vectors and methods for transformation of eucaryotic cells
US4959455A (en) 1986-07-14 1990-09-25 Genetics Institute, Inc. Primate hematopoietic growth factors IL-3 and pharmaceutical compositions
US4912040A (en) 1986-11-14 1990-03-27 Genetics Institute, Inc. Eucaryotic expression system
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
WO1996033735A1 (en) 1995-04-27 1996-10-31 Abgenix, Inc. Human antibodies derived from immunized xenomice
DE69120146T2 (de) 1990-01-12 1996-12-12 Cell Genesys Inc Erzeugung xenogener antikörper
ATE158021T1 (de) 1990-08-29 1997-09-15 Genpharm Int Produktion und nützung nicht-menschliche transgentiere zur produktion heterologe antikörper
ES2301158T3 (es) 1992-07-24 2008-06-16 Amgen Fremont Inc. Produccion de anticuerpos xenogenicos.
US6342220B1 (en) 1997-08-25 2002-01-29 Genentech, Inc. Agonist antibodies
EP3960855A1 (en) 2001-12-28 2022-03-02 Chugai Seiyaku Kabushiki Kaisha Method for stabilizing proteins
US20040101920A1 (en) 2002-11-01 2004-05-27 Czeslaw Radziejewski Modification assisted profiling (MAP) methodology
KR101225299B1 (ko) 2003-12-10 2013-01-24 메다렉스, 인코포레이티드 인터페론 알파 항체 및 그의 용도
DK1959981T3 (da) 2005-02-03 2020-01-27 Coda Therapeutics Ltd Anti-connexin 43 forbindelser til behandling af kroniske sår
MX2010012324A (es) * 2008-05-15 2011-01-14 Biogen Idec Inc Anticuerpos anti-fn14 y usos de los mismos.
US20110223204A1 (en) 2008-06-04 2011-09-15 Bradford J Duft Treatment of pain with gap junction modulation compounds
CN103429732B (zh) 2010-12-27 2015-09-16 Lsip基金运营联合公司 iPS细胞及其制造方法
CA2921652A1 (en) * 2013-08-21 2015-02-26 Manuel A. Riquelme Compositions and methods for targeting connexin hemichannels
US9493552B2 (en) * 2013-11-15 2016-11-15 China Synthetic Rubber Corporation Therapeutic biologic for treatment of hepatocellular carcinoma
US10465188B2 (en) 2014-08-22 2019-11-05 Auckland Uniservices Limited Channel modulators
WO2017024465A1 (en) 2015-08-10 2017-02-16 Innovent Biologics (Suzhou) Co., Ltd. Pd-1 antibodies
EP3419998A4 (en) * 2016-02-26 2019-09-25 The Board of Regents of The University of Texas System CONNEXIN (CX) 43 HEMICANAL BINDING ANTIBODIES AND USES THEREOF
US12227561B2 (en) 2018-04-02 2025-02-18 Alamab Therapeutics, Inc. Connexin 43 antibodies and use thereof
IL285369B2 (en) 2019-02-04 2025-10-01 Alamab Therapeutics Inc Connexin 43 antibodies and their use
JP2023537316A (ja) * 2020-07-31 2023-08-31 アラマブ セラピューティクス, インコーポレイテッド 抗コネキシン抗体製剤

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