JP2014076062A5 - - Google Patents

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Publication number
JP2014076062A5
JP2014076062A5 JP2013268626A JP2013268626A JP2014076062A5 JP 2014076062 A5 JP2014076062 A5 JP 2014076062A5 JP 2013268626 A JP2013268626 A JP 2013268626A JP 2013268626 A JP2013268626 A JP 2013268626A JP 2014076062 A5 JP2014076062 A5 JP 2014076062A5
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JP
Japan
Prior art keywords
antibody
seq
heavy chain
pharmaceutical composition
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2013268626A
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English (en)
Japanese (ja)
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JP2014076062A (ja
JP5933517B2 (ja
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Publication date
Priority claimed from PCT/AU2011/000155 external-priority patent/WO2011100786A1/en
Application filed filed Critical
Publication of JP2014076062A publication Critical patent/JP2014076062A/ja
Publication of JP2014076062A5 publication Critical patent/JP2014076062A5/ja
Application granted granted Critical
Publication of JP5933517B2 publication Critical patent/JP5933517B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2013268626A 2010-08-17 2013-12-26 ヒト化抗インターロイキン3レセプターα鎖抗体 Active JP5933517B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US37448910P 2010-08-17 2010-08-17
US61/374,489 2010-08-17
AUPCT/AU2011/000155 2011-02-17
PCT/AU2011/000155 WO2011100786A1 (en) 2010-02-17 2011-02-17 Compositions and methods for targeting type 1 interferon producing cells

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2013524306A Division JP5524418B2 (ja) 2010-08-17 2011-08-17 ヒト化抗インターロイキン3レセプターα鎖抗体

Publications (3)

Publication Number Publication Date
JP2014076062A JP2014076062A (ja) 2014-05-01
JP2014076062A5 true JP2014076062A5 (enExample) 2014-09-18
JP5933517B2 JP5933517B2 (ja) 2016-06-08

Family

ID=45604615

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2013524306A Active JP5524418B2 (ja) 2010-08-17 2011-08-17 ヒト化抗インターロイキン3レセプターα鎖抗体
JP2013268626A Active JP5933517B2 (ja) 2010-08-17 2013-12-26 ヒト化抗インターロイキン3レセプターα鎖抗体

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2013524306A Active JP5524418B2 (ja) 2010-08-17 2011-08-17 ヒト化抗インターロイキン3レセプターα鎖抗体

Country Status (13)

Country Link
US (3) US8569461B2 (enExample)
EP (2) EP2606069B1 (enExample)
JP (2) JP5524418B2 (enExample)
KR (1) KR101347688B1 (enExample)
CN (1) CN103025761B (enExample)
CA (1) CA2805176C (enExample)
DK (1) DK2606069T3 (enExample)
ES (1) ES2506340T3 (enExample)
GB (1) GB2488091B (enExample)
IL (1) IL225631A (enExample)
NZ (1) NZ604510A (enExample)
PL (1) PL2606069T3 (enExample)
WO (1) WO2012021934A1 (enExample)

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JP7251981B2 (ja) 2016-03-24 2023-04-04 バイエル ファーマ アクチエンゲゼルシャフト 酵素開裂基を有する細胞毒性活性剤のプロドラッグ
CN109310781B (zh) * 2016-06-15 2024-06-18 拜耳制药股份公司 具有ksp抑制剂和抗-cd123-抗体的特异性抗体-药物-缀合物(adc)
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WO2018114804A1 (de) 2016-12-21 2018-06-28 Bayer Pharma Aktiengesellschaft Spezifische antikörper-wirkstoff-konjugate (adcs) mit ksp-inhibitoren
TWI757499B (zh) 2017-06-02 2022-03-11 美商輝瑞大藥廠 對flt3具特異性之抗體及其用途
CA3089754A1 (en) 2018-01-31 2019-08-08 Bayer Aktiengesellschaft Antibody drug conjugates (adcs) with nampt inhibitors
CN119954959A (zh) * 2019-03-11 2025-05-09 詹森生物科技公司 抗Vβ17/抗CD123双特异性抗体
EP3966242A1 (en) 2019-05-04 2022-03-16 Inhibrx, Inc. Cd123-binding polypeptides and uses thereof
WO2021013693A1 (en) 2019-07-23 2021-01-28 Bayer Pharma Aktiengesellschaft Antibody drug conjugates (adcs) with nampt inhibitors
KR20230084508A (ko) 2020-09-11 2023-06-13 얀센 바이오테크 인코포레이티드 베타 사슬 매개 면역을 조절하기 위한 방법 및 조성물
AU2021414400A1 (en) 2020-12-31 2023-08-17 Innate Pharma Multifunctional natural killer (nk) cell engagers binding to nkp46 and cd123
AU2022323756A1 (en) * 2021-08-06 2023-12-14 Cimeio Therapeutics Ag Discernible cell surface protein variants for use in cell therapy
AU2023274452A1 (en) 2022-05-27 2025-01-16 Innate Pharma Natural killer (nk) cell engagers binding to nkp46 and bcma variants with fc-engineering
EP4296280A1 (en) 2022-06-21 2023-12-27 F. Hoffmann-La Roche AG Cd123 and cd200 as markers for the diagnosis and immune-eradication of leukemic stem cells (lscs)
EP4619044A1 (en) 2022-11-17 2025-09-24 Hans-Georg Lerchen Antibody-drug-conjugates cleavable in a tumor microenvironment

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