JP2021512125A5 - - Google Patents
Info
- Publication number
- JP2021512125A5 JP2021512125A5 JP2020541971A JP2020541971A JP2021512125A5 JP 2021512125 A5 JP2021512125 A5 JP 2021512125A5 JP 2020541971 A JP2020541971 A JP 2020541971A JP 2020541971 A JP2020541971 A JP 2020541971A JP 2021512125 A5 JP2021512125 A5 JP 2021512125A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- substituted
- heterocyclyl
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18154826.4 | 2018-02-02 | ||
| EP18154826 | 2018-02-02 | ||
| PCT/EP2019/051991 WO2019149658A1 (en) | 2018-02-02 | 2019-01-28 | Pyrazole- and indazole-substituted oxadiazolopyridine derivatives for use as ghrelin o-acyl transferase (goat) inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021512125A JP2021512125A (ja) | 2021-05-13 |
| JP2021512125A5 true JP2021512125A5 (https=) | 2022-01-28 |
| JP7225253B2 JP7225253B2 (ja) | 2023-02-20 |
Family
ID=61157052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020541971A Active JP7225253B2 (ja) | 2018-02-02 | 2019-01-28 | グレリンｏ－アシルトランスフェラーゼ（ｇｏａｔ）阻害剤として使用するためのピラゾール置換及びインダゾール置換オキサジアゾロピリジン誘導体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11136337B2 (https=) |
| EP (1) | EP3746449B1 (https=) |
| JP (1) | JP7225253B2 (https=) |
| CN (1) | CN111630055B (https=) |
| WO (1) | WO2019149658A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201811804QA (en) * | 2016-08-05 | 2019-01-30 | Boehringer Ingelheim Int | Oxadiazolopyridine derivates for use as ghrelin o-acyl transferase (goat) inhibitors |
| MX2020007994A (es) | 2018-02-02 | 2020-09-09 | Boehringer Ingelheim Int | Derivados de triazolopirimidina para usar como inhibidores de ghrelin o-aciltransferasa (goat). |
| AU2019215707A1 (en) | 2018-02-02 | 2020-07-09 | Boehringer Ingelheim International Gmbh | Benzyl-, (pyridin-3-yl)methyl- or (pyridin-4-yl)methyl-substituted oxadiazolopyridine derivatives as ghrelin O-acyl transferase (GOAT) inhibitors |
| TW202140440A (zh) | 2020-02-28 | 2021-11-01 | 美商克力歐普股份有限公司 | Gpr40激動劑 |
| WO2021233882A1 (en) | 2020-05-22 | 2021-11-25 | Boehringer Ingelheim International Gmbh | Process for manufacturing alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridine-carboxylate |
| CN115916789B (zh) | 2020-05-22 | 2025-06-27 | 勃林格殷格翰国际有限公司 | 制备烷基7-氨基-5-甲基-[1,2,5]噁二唑并[3,4-b]吡啶羧酸酯的连续方法 |
| CN116082437A (zh) * | 2022-01-26 | 2023-05-09 | 石家庄迪斯凯威医药科技有限公司 | 一种多环化合物及其作为胃饥饿素受体激动剂的用途 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004082383A1 (en) | 2003-03-17 | 2004-09-30 | Basf Aktiengesellschaft | Use of triazolopyrimidines for combating nematode diseases of plants |
| CA2677932A1 (en) | 2007-02-15 | 2008-08-21 | Indiana University Research And Technology Corporation | Glucagon/glp-1 receptor co-agonists |
| EP2158214B1 (en) | 2007-06-15 | 2011-08-17 | Zealand Pharma A/S | Glucagon analogues |
| UA105362C2 (en) * | 2008-04-02 | 2014-05-12 | Бьорингер Ингельхайм Интернациональ Гмбх | 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators |
| JP5635531B2 (ja) | 2008-12-15 | 2014-12-03 | ジーランド ファーマ アクティーゼルスカブ | グルカゴン類似体 |
| CN102282167B (zh) | 2008-12-15 | 2014-08-13 | 西兰制药公司 | 胰高血糖素类似物 |
| ES2477880T3 (es) | 2008-12-15 | 2014-07-18 | Zealand Pharma A/S | Análogos del glucagón |
| EP2370462B1 (en) | 2008-12-15 | 2014-07-16 | Zealand Pharma A/S | Glucagon analogues |
| AU2010272944B2 (en) | 2009-07-13 | 2015-11-19 | Zealand Pharma A/S | Acylated glucagon analogues |
| UY33462A (es) | 2010-06-23 | 2012-01-31 | Zealand Pharma As | Analogos de glucagon |
| US9169310B2 (en) | 2010-06-24 | 2015-10-27 | Zealand Pharma A/S | Glucagon analogues |
| IN2014CN04401A (https=) | 2011-12-23 | 2015-09-04 | Zealand Pharma As | |
| US9238639B2 (en) | 2012-02-24 | 2016-01-19 | Takeda Pharmaceutical Company Limited | Aromatic ring compound |
| EP2863910B1 (en) * | 2012-06-20 | 2020-03-11 | University Of Virginia Patent Foundation | Compositions and methods for regulating glucose homeostasis and insulin action |
| TWI608013B (zh) | 2012-09-17 | 2017-12-11 | 西蘭製藥公司 | 升糖素類似物 |
| UA118034C2 (uk) | 2013-11-14 | 2018-11-12 | Елі Ліллі Енд Компані | Заміщений піперидилетилпіримідин як інгібітор грелін-o-ацилтрансферази |
| EP3193939A4 (en) | 2014-09-17 | 2018-10-24 | The Regents of The University of California | Small lipopeptidomimetic inhibitors of ghrelin o-acyl transferase |
| WO2016123275A1 (en) * | 2015-01-30 | 2016-08-04 | Boehringer Ingelheim International Gmbh | Aldosterone synthase inhibitors |
| AR104672A1 (es) | 2015-04-15 | 2017-08-09 | Lilly Co Eli | Inhibidores de grelina o-aciltransferasa |
| AR104673A1 (es) | 2015-04-15 | 2017-08-09 | Lilly Co Eli | Inhibidores de grelina o-aciltransferasa |
| SG11201811804QA (en) | 2016-08-05 | 2019-01-30 | Boehringer Ingelheim Int | Oxadiazolopyridine derivates for use as ghrelin o-acyl transferase (goat) inhibitors |
| AU2019215707A1 (en) * | 2018-02-02 | 2020-07-09 | Boehringer Ingelheim International Gmbh | Benzyl-, (pyridin-3-yl)methyl- or (pyridin-4-yl)methyl-substituted oxadiazolopyridine derivatives as ghrelin O-acyl transferase (GOAT) inhibitors |
| WO2019149659A1 (en) * | 2018-02-02 | 2019-08-08 | Boehringer Ingelheim International Gmbh | Heterocyclyl-substituted oxadiazolopyridine derivatives for use as ghrelin o-acyl transferase (goat) inhibitors |
-
2019
- 2019-01-28 EP EP19702084.5A patent/EP3746449B1/en active Active
- 2019-01-28 JP JP2020541971A patent/JP7225253B2/ja active Active
- 2019-01-28 WO PCT/EP2019/051991 patent/WO2019149658A1/en not_active Ceased
- 2019-01-28 US US16/966,485 patent/US11136337B2/en active Active
- 2019-01-28 CN CN201980009508.9A patent/CN111630055B/zh active Active
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