JP2021512125A5 - - Google Patents

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Publication number
JP2021512125A5
JP2021512125A5 JP2020541971A JP2020541971A JP2021512125A5 JP 2021512125 A5 JP2021512125 A5 JP 2021512125A5 JP 2020541971 A JP2020541971 A JP 2020541971A JP 2020541971 A JP2020541971 A JP 2020541971A JP 2021512125 A5 JP2021512125 A5 JP 2021512125A5
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JP
Japan
Prior art keywords
group
alkyl
substituted
heterocyclyl
phenyl
Prior art date
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JP2020541971A
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English (en)
Japanese (ja)
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JP7225253B2 (ja
JPWO2019149658A5 (https=
JP2021512125A (ja
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Priority claimed from PCT/EP2019/051991 external-priority patent/WO2019149658A1/en
Publication of JP2021512125A publication Critical patent/JP2021512125A/ja
Publication of JP2021512125A5 publication Critical patent/JP2021512125A5/ja
Publication of JPWO2019149658A5 publication Critical patent/JPWO2019149658A5/ja
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Publication of JP7225253B2 publication Critical patent/JP7225253B2/ja
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JP2020541971A 2018-02-02 2019-01-28 グレリンｏ－アシルトランスフェラーゼ（ｇｏａｔ）阻害剤として使用するためのピラゾール置換及びインダゾール置換オキサジアゾロピリジン誘導体 Active JP7225253B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18154826.4 2018-02-02
EP18154826 2018-02-02
PCT/EP2019/051991 WO2019149658A1 (en) 2018-02-02 2019-01-28 Pyrazole- and indazole-substituted oxadiazolopyridine derivatives for use as ghrelin o-acyl transferase (goat) inhibitors

Publications (4)

Publication Number Publication Date
JP2021512125A JP2021512125A (ja) 2021-05-13
JP2021512125A5 true JP2021512125A5 (https=) 2022-01-28
JPWO2019149658A5 JPWO2019149658A5 (https=) 2022-01-28
JP7225253B2 JP7225253B2 (ja) 2023-02-20

Family

ID=61157052

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020541971A Active JP7225253B2 (ja) 2018-02-02 2019-01-28 グレリンｏ－アシルトランスフェラーゼ（ｇｏａｔ）阻害剤として使用するためのピラゾール置換及びインダゾール置換オキサジアゾロピリジン誘導体

Country Status (5)

Country Link
US (1) US11136337B2 (https=)
EP (1) EP3746449B1 (https=)
JP (1) JP7225253B2 (https=)
CN (1) CN111630055B (https=)
WO (1) WO2019149658A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9994591B2 (en) * 2016-08-05 2018-06-12 Boehringer Ingelheim International Gmbh Oxadiazolopyridine derivates for use as ghrelin O-acyl transferase (GOAT) inhibitors
WO2019149657A1 (en) 2018-02-02 2019-08-08 Boehringer Ingelheim International Gmbh Benzyl-, (pyridin-3-yl)methyl- or (pyridin-4-yl)methyl-substituted oxadiazolopyridine derivatives as ghrelin o-acyl transferase (goat) inhibitors
MX2020007994A (es) 2018-02-02 2020-09-09 Boehringer Ingelheim Int Derivados de triazolopirimidina para usar como inhibidores de ghrelin o-aciltransferasa (goat).
IL295825A (en) 2020-02-28 2022-10-01 Kallyope Inc gpr40 agonists
DK4153599T3 (da) 2020-05-22 2024-06-17 Boehringer Ingelheim Int Fremgangsmåde til at fremstille alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-carboxylat
ES2991340T3 (es) 2020-05-22 2024-12-03 Boehringer Ingelheim Int Procedimiento continuo de fabricación de 7-amino-5-metil-[1,2,5]oxadiazolo[3,4-b]piridín-carboxilato de alquilo
CN116082437A (zh) * 2022-01-26 2023-05-09 石家庄迪斯凯威医药科技有限公司 一种多环化合物及其作为胃饥饿素受体激动剂的用途

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WO2004082383A1 (en) 2003-03-17 2004-09-30 Basf Aktiengesellschaft Use of triazolopyrimidines for combating nematode diseases of plants
AU2008216265B2 (en) 2007-02-15 2014-04-03 Indiana University Research And Technology Corporation Glucagon/GLP-1 receptor co-agonists
JP5385266B2 (ja) 2007-06-15 2014-01-08 ジーランド ファーマ アクティーゼルスカブ グルカゴン類似体
UA105362C2 (en) * 2008-04-02 2014-05-12 Бьорингер Ингельхайм Интернациональ Гмбх 1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators
JP5635531B2 (ja) 2008-12-15 2014-12-03 ジーランド ファーマ アクティーゼルスカブ グルカゴン類似体
KR20110126592A (ko) 2008-12-15 2011-11-23 질랜드 파마 에이/에스 글루카곤 유사체
US8685919B2 (en) 2008-12-15 2014-04-01 Zealand Pharma A/S Glucagon analogues
WO2010070255A1 (en) 2008-12-15 2010-06-24 Zealand Pharma A/S Glucagon analogues
AP3329A (en) 2009-07-13 2015-06-30 Zealand Pharma As Acylated glucagon analogues
UY33462A (es) 2010-06-23 2012-01-31 Zealand Pharma As Analogos de glucagon
PH12012502472A1 (en) 2010-06-24 2013-03-25 Zealand Pharma As Glucagon analogues
WO2013092703A2 (en) 2011-12-23 2013-06-27 Zealand Pharma A/S Glucagon analogues
JP6106179B2 (ja) * 2012-02-24 2017-03-29 武田薬品工業株式会社 芳香環化合物
WO2013192388A1 (en) * 2012-06-20 2013-12-27 University Of Virginia Patent Foundation Compositions and methods for regulating glucose homeostasis and insulin action
TWI608013B (zh) 2012-09-17 2017-12-11 西蘭製藥公司 升糖素類似物
UA118034C2 (uk) 2013-11-14 2018-11-12 Елі Ліллі Енд Компані Заміщений піперидилетилпіримідин як інгібітор грелін-o-ацилтрансферази
EP3193939A4 (en) 2014-09-17 2018-10-24 The Regents of The University of California Small lipopeptidomimetic inhibitors of ghrelin o-acyl transferase
US10131642B1 (en) * 2015-01-30 2018-11-20 Boehringer Ingelheim International Gmbh Aldosterone synthase inhibitors
AR104673A1 (es) 2015-04-15 2017-08-09 Lilly Co Eli Inhibidores de grelina o-aciltransferasa
AR104672A1 (es) 2015-04-15 2017-08-09 Lilly Co Eli Inhibidores de grelina o-aciltransferasa
US9994591B2 (en) * 2016-08-05 2018-06-12 Boehringer Ingelheim International Gmbh Oxadiazolopyridine derivates for use as ghrelin O-acyl transferase (GOAT) inhibitors
WO2019149657A1 (en) * 2018-02-02 2019-08-08 Boehringer Ingelheim International Gmbh Benzyl-, (pyridin-3-yl)methyl- or (pyridin-4-yl)methyl-substituted oxadiazolopyridine derivatives as ghrelin o-acyl transferase (goat) inhibitors
AU2019215709A1 (en) * 2018-02-02 2020-07-16 Boehringer Ingelheim International Gmbh Heterocyclyl-substituted oxadiazolopyridine derivatives for use as ghrelin O-acyl transferase (GOAT) inhibitors

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