JP2021507677A5 - - Google Patents

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Publication number
JP2021507677A5
JP2021507677A5 JP2020517858A JP2020517858A JP2021507677A5 JP 2021507677 A5 JP2021507677 A5 JP 2021507677A5 JP 2020517858 A JP2020517858 A JP 2020517858A JP 2020517858 A JP2020517858 A JP 2020517858A JP 2021507677 A5 JP2021507677 A5 JP 2021507677A5
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JP
Japan
Prior art keywords
seq
amino acid
acid sequence
antigen
binding fragment
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Application number
JP2020517858A
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English (en)
Japanese (ja)
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JP2021507677A (ja
JP7438937B2 (ja
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Priority claimed from PCT/US2018/062863 external-priority patent/WO2019108662A1/en
Publication of JP2021507677A publication Critical patent/JP2021507677A/ja
Publication of JP2021507677A5 publication Critical patent/JP2021507677A5/ja
Priority to JP2023191236A priority Critical patent/JP2024016204A/ja
Application granted granted Critical
Publication of JP7438937B2 publication Critical patent/JP7438937B2/ja
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JP2020517858A 2017-11-30 2018-11-28 抗ｔｒｋｂモノクローナル抗体および使用の方法 Active JP7438937B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023191236A JP2024016204A (ja) 2017-11-30 2023-11-09 抗ｔｒｋｂモノクローナル抗体および使用の方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762592657P 2017-11-30 2017-11-30
US62/592,657 2017-11-30
PCT/US2018/062863 WO2019108662A1 (en) 2017-11-30 2018-11-28 Anti-trkb monoclonal antibodies and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023191236A Division JP2024016204A (ja) 2017-11-30 2023-11-09 抗ｔｒｋｂモノクローナル抗体および使用の方法

Publications (3)

Publication Number Publication Date
JP2021507677A JP2021507677A (ja) 2021-02-25
JP2021507677A5 true JP2021507677A5 (enExample) 2022-01-04
JP7438937B2 JP7438937B2 (ja) 2024-02-27

Family

ID=64665125

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020517858A Active JP7438937B2 (ja) 2017-11-30 2018-11-28 抗ｔｒｋｂモノクローナル抗体および使用の方法
JP2023191236A Pending JP2024016204A (ja) 2017-11-30 2023-11-09 抗ｔｒｋｂモノクローナル抗体および使用の方法

Family Applications After (1)

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JP2023191236A Pending JP2024016204A (ja) 2017-11-30 2023-11-09 抗ｔｒｋｂモノクローナル抗体および使用の方法

Country Status (18)

Country Link
US (3) US11066474B2 (enExample)
EP (1) EP3717514A1 (enExample)
JP (2) JP7438937B2 (enExample)
KR (1) KR20200090779A (enExample)
CN (2) CN111372949B (enExample)
AU (3) AU2018375340B2 (enExample)
BR (1) BR112020006976A2 (enExample)
CA (1) CA3083452A1 (enExample)
CL (3) CL2020000855A1 (enExample)
CO (1) CO2020004075A2 (enExample)
EA (1) EA202090966A1 (enExample)
IL (1) IL273538B2 (enExample)
MA (1) MA51207A (enExample)
MX (3) MX2020003550A (enExample)
MY (1) MY203247A (enExample)
PH (1) PH12020550409A1 (enExample)
SG (1) SG11202002665UA (enExample)
WO (1) WO2019108662A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10793634B2 (en) 2017-06-09 2020-10-06 Boehringer Ingelheim International Gmbh Anti-TrkB antibodies
EP3717514A1 (en) * 2017-11-30 2020-10-07 Regeneron Pharmaceuticals, Inc. Anti-trkb monoclonal antibodies and methods of use
IL274740B2 (en) * 2017-11-30 2024-06-01 Regeneron Pharma Non-human animals comprising a humanized trkb locus
CN113557301B (zh) * 2019-03-04 2025-03-07 公益财团法人东京都医学综合研究所 编码Trk片段的核酸构建体及其利用
WO2021155141A1 (en) * 2020-01-30 2021-08-05 Fred Hutchinson Cancer Research Center Antibody-based compositions for targeting tropomyosin receptor kinase b (trkb) isoforms
WO2023125485A1 (en) * 2021-12-28 2023-07-06 4B Technologies (Beijing) Co., Limited TrkB ANTIBODY AND APPLICATION THEREOF
EP4501941A1 (en) 2022-03-30 2025-02-05 PeptiDream Inc. Peptide complex having trkb binding activity

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5877016A (en) 1994-03-18 1999-03-02 Genentech, Inc. Human trk receptors and neurotrophic factor inhibitors
US6225282B1 (en) 1996-01-05 2001-05-01 Genentech, Inc. Treatment of hearing impairments
US6596541B2 (en) 2000-10-31 2003-07-22 Regeneron Pharmaceuticals, Inc. Methods of modifying eukaryotic cells
GT200600240A (es) 2005-06-06 2007-03-14 Anticuerpos monoclonales anti-trkb y usos de los mismos
EP1988923A1 (en) * 2006-02-02 2008-11-12 Rinat Neuroscience Corp. Methods for treating unwanted weight loss or eating disorders by administering a trkb agonist
US7935342B2 (en) 2006-02-02 2011-05-03 Rinat Neuroscience Corp. Methods for treating obesity by administering a trkB antagonist
RS52176B (sr) 2006-06-02 2012-08-31 Regeneron Pharmaceuticals Inc. Antitela visokog afiniteta prema humanom il-6 receptoru
CA2669205A1 (en) 2006-11-09 2008-05-15 Irm Llc Agonist trkb antibodies and uses thereof
BRPI0720473A2 (pt) * 2006-12-20 2014-01-14 Rinat Neuroscience Corp Agonistas de trkb para tratamento de distúbios autoimunes
CA2701189C (en) 2007-10-11 2017-05-16 Biogen Idec Ma Inc. Methods for treating pressure induced optic neuropathy, preventing neuronal degeneration and promoting neuronal cell survival via administration of lingo-1 antagonists and trkb agonists
CN102015769B (zh) 2008-01-17 2014-12-10 Irm责任有限公司 改进的抗-trkb抗体
WO2010086828A2 (en) 2009-02-02 2010-08-05 Rinat Neuroscience Corporation Agonist anti-trkb monoclonal antibodies
WO2011103667A1 (en) 2010-02-26 2011-09-01 6452728 Canada Inc. Agonistic antibodies to trkb receptors and uses thereof
GB2491106A (en) 2011-05-18 2012-11-28 Univ Basel Antibodies against tropomyosin-related kinase B receptors
WO2015077672A1 (en) 2013-11-25 2015-05-28 The Regents Of The University Of California Santa Cruz Piericidin bacterial inhibitors
JP6868394B2 (ja) 2014-05-16 2021-05-12 ファイザー・インク 二重特異性抗体
BR112018001900A2 (pt) 2015-07-28 2018-09-18 Otonomy, Inc. composições agonistas de trkb ou trkc e métodos para o tratamento de condições óticas
TW201730206A (zh) 2015-11-17 2017-09-01 葛蘭素史克智慧財產發展有限公司 用於治療神經及其他疾病之結合激動劑
JP2019517787A (ja) * 2016-05-03 2019-06-27 ザ スクリプス リサーチ インスティテュート 神経変性障害の処置のためのＴｒｋＢアゴニスト抗体
US9914781B1 (en) 2016-11-08 2018-03-13 Glaxosmithkline Intellectual Property Development Limited Binding agonist for treatment of neurological and other disorders
EP3596126A4 (en) * 2017-03-15 2021-03-03 Tsinghua University NOVEL ANTI-TRKB ANTIBODIES
EP3717514A1 (en) * 2017-11-30 2020-10-07 Regeneron Pharmaceuticals, Inc. Anti-trkb monoclonal antibodies and methods of use

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