|
US4751180A
(en)
|
1985-03-28 |
1988-06-14 |
Chiron Corporation |
Expression using fused genes providing for protein product
|
|
US4935233A
(en)
|
1985-12-02 |
1990-06-19 |
G. D. Searle And Company |
Covalently linked polypeptide cell modulators
|
|
US5225538A
(en)
|
1989-02-23 |
1993-07-06 |
Genentech, Inc. |
Lymphocyte homing receptor/immunoglobulin fusion proteins
|
|
SE509359C2
(sv)
|
1989-08-01 |
1999-01-18 |
Cemu Bioteknik Ab |
Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel
|
|
US6267964B1
(en)
|
1989-08-01 |
2001-07-31 |
Affibody Technology Sweden Ab |
Stabilized protein or peptide conjugates able to bond albumin having extended biological half-lives
|
|
GB8918616D0
(en)
|
1989-08-15 |
1989-09-27 |
Univ Glasgow |
Herpes simplex virus type 1 mutant
|
|
US20020164782A1
(en)
|
1999-02-10 |
2002-11-07 |
Gregory Richard J. |
Adenovirus vectors for gene therapy
|
|
JPH04292169A
(ja)
|
1991-03-19 |
1992-10-16 |
Sekisui Chem Co Ltd |
ハイブリッド型人工膵臓
|
|
US5418618A
(en)
|
1992-03-09 |
1995-05-23 |
Mita Industrial Co., Ltd. |
Tone processing method for forming a halftone image
|
|
US5804413A
(en)
|
1992-07-31 |
1998-09-08 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Herpes simplex virus strains for gene transfer
|
|
US5808656A
(en)
|
1993-09-15 |
1998-09-15 |
Oce Printing Systems Gmbh |
Arrangement and process for generating a matrix image on a photosensitive recording substrate
|
|
WO1995019570A1
(en)
|
1994-01-14 |
1995-07-20 |
Genentech, Inc. |
Antagonists to insulin receptor tyrosine kinase inhibitor
|
|
GB9415319D0
(en)
|
1994-07-29 |
1994-09-21 |
Medical Res Council |
HSV viral vector
|
|
US5846782A
(en)
|
1995-11-28 |
1998-12-08 |
Genvec, Inc. |
Targeting adenovirus with use of constrained peptide motifs
|
|
US6001650A
(en)
|
1995-08-03 |
1999-12-14 |
Avigen, Inc. |
High-efficiency wild-type-free AAV helper functions
|
|
US6825396B2
(en)
|
1996-06-12 |
2004-11-30 |
Board Of Trustees Operating Michigan State University |
Methods for tissue specific synthesis of protein in eggs of transgenic hens
|
|
CA2280957A1
(en)
|
1997-02-14 |
1998-08-20 |
Leslie Orgel |
Methods and compositions for delivery of therapeutic agents to bone tissue employing conjugates of negatively charged peptide oligomers with therapeutic agents
|
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
EP1002119A1
(en)
|
1997-07-31 |
2000-05-24 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Targeted hsv vectors
|
|
US20040019923A1
(en)
|
1997-10-16 |
2004-01-29 |
Ivarie Robert D. |
Exogenous proteins expressed in avians and their eggs
|
|
US5932465A
(en)
|
1997-10-16 |
1999-08-03 |
Icos Corporation |
Phosphodiesterase 8A
|
|
AU752946B2
(en)
|
1997-10-16 |
2002-10-03 |
Avigenics, Inc. |
Vectors comprising a magnum-specific promoter for avian transgenesis
|
|
PT1032662E
(pt)
|
1997-11-07 |
2006-07-31 |
Trillium Therapeutics Inc |
Metodos e composicoes para imunomodulacao.
|
|
US6894022B1
(en)
|
1998-08-27 |
2005-05-17 |
Eidgenossische Technische Hochschule Zurich |
Growth factor modified protein matrices for tissue engineering
|
|
US6272859B1
(en)
|
1998-10-02 |
2001-08-14 |
Caterpillar Inc. |
Device for controlling a variable geometry turbocharger
|
|
US6043056A
(en)
|
1998-11-06 |
2000-03-28 |
Incyte Pharmaceuticals, Inc. |
Cell surface glycoproteins
|
|
HK1044468A1
(zh)
|
1998-12-03 |
2002-10-25 |
海斯塔泰克有限责任公司 |
治療哮喘和炎症的小肽和方法
|
|
US6596535B1
(en)
|
1999-08-09 |
2003-07-22 |
Targeted Genetics Corporation |
Metabolically activated recombinant viral vectors and methods for the preparation and use
|
|
JP3983449B2
(ja)
|
1999-10-15 |
2007-09-26 |
株式会社リコー |
パルス幅変調回路、光書き込み装置及び画像形成装置
|
|
US7608681B2
(en)
|
1999-12-24 |
2009-10-27 |
Genentech, Inc. |
Methods and compositions for prolonging elimination half-times of bioactive compounds
|
|
ATE447622T1
(de)
|
2000-02-23 |
2009-11-15 |
Pxe Internat Inc |
Methoden und zusammensetzungen zur diagnose und behandlung von pseudoxanthoma elasticum und ähnlichen zuständen
|
|
JP2001274989A
(ja)
|
2000-03-27 |
2001-10-05 |
Ricoh Co Ltd |
画像処理装置及び画像処理方法並びにプリンタ出力装置
|
|
DE20121960U1
(de)
|
2000-04-06 |
2004-01-15 |
Epigenomics Ag |
Nukleinsäuren für die Diagnose von mit Metastase assoziierten Krankheiten
|
|
US20040030167A1
(en)
|
2000-08-08 |
2004-02-12 |
Hiroaki Takayama |
3-Methyl-20-epi-vitamin d derivatives
|
|
US6521645B2
(en)
|
2000-11-20 |
2003-02-18 |
The University Of Kansas Medical Center |
Methods for the treatment and prevention of urinary stone disease
|
|
EP1355919B1
(en)
|
2000-12-12 |
2010-11-24 |
MedImmune, LLC |
Molecules with extended half-lives, compositions and uses thereof
|
|
US20020108132A1
(en)
|
2001-02-02 |
2002-08-08 |
Avigenics Inc. |
Production of a monoclonal antibody by a transgenic chicken
|
|
US7211395B2
(en)
|
2001-03-09 |
2007-05-01 |
Dyax Corp. |
Serum albumin binding moieties
|
|
WO2002092020A2
(en)
|
2001-03-23 |
2002-11-21 |
The Burnham Institute |
Compositions and methods for modulating bone mineral deposition
|
|
US7888372B2
(en)
|
2001-03-23 |
2011-02-15 |
National Institutes Of Health (Nih) |
Compositions and methods for modulating bone mineral deposition
|
|
US20030191073A1
(en)
|
2001-11-07 |
2003-10-09 |
Challita-Eid Pia M. |
Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer
|
|
AU2002324700A1
(en)
|
2001-08-14 |
2003-03-03 |
Bayer Ag |
Nucleic acid and amino acid sequences involved in pain
|
|
WO2003025146A2
(en)
|
2001-09-18 |
2003-03-27 |
Avigenics, Inc. |
Production of a transgenic avian by cytoplasmic injection
|
|
EP1537140B1
(en)
|
2001-11-07 |
2013-01-02 |
Agensys, Inc. |
Nucleic acid and corresponding protein entitled 161p2f10b useful in treatment and detection of cancer
|
|
US7335761B2
(en)
|
2001-11-30 |
2008-02-26 |
Avigenics, Inc. |
Avian gene expression controlling regions
|
|
US7294507B2
(en)
|
2001-11-30 |
2007-11-13 |
Avigenics, Inc. |
Ovomucoid promoters and methods of use
|
|
US6875588B2
(en)
|
2001-11-30 |
2005-04-05 |
Avigenics, Inc. |
Ovomucoid promoter and methods of use
|
|
US7858297B2
(en)
|
2001-12-18 |
2010-12-28 |
Centre National De La Recherche Scientifique Cnrs |
Chemokine-binding protein and methods of use
|
|
WO2003072593A2
(en)
|
2002-02-21 |
2003-09-04 |
University Of Virginia Patent Foundation |
Bone targeting peptides
|
|
AU2003210806A1
(en)
|
2002-03-05 |
2003-09-22 |
Eli Lilly And Company |
Heterologous g-csf fusion proteins
|
|
US20040071705A1
(en)
|
2002-06-21 |
2004-04-15 |
Dyax Corporation |
Serum protein-associated target-specific ligands and identification method therefor
|
|
US20040224893A1
(en)
|
2003-05-06 |
2004-11-11 |
Li-Hsien Wang |
Methods of using IL-1 antagonists to treat neointimal hyperplasia
|
|
US20050090001A1
(en)
|
2003-10-07 |
2005-04-28 |
Parker Stephen H. |
Cell lines and methods for producing proteins
|
|
CN102816241B
(zh)
|
2004-02-09 |
2015-07-22 |
人类基因科学公司 |
清蛋白融合蛋白
|
|
PL1759001T3
(pl)
|
2004-04-21 |
2011-09-30 |
Alexion Pharma Inc |
Koniugaty dostarczane do kości i sposób ich zastosowania do nakierowywania białek do kości
|
|
US9055984B2
(en)
|
2004-04-21 |
2015-06-16 |
DePuy Synthes Products, Inc. |
Sternal reconstruction system
|
|
US20050287284A1
(en)
|
2004-06-28 |
2005-12-29 |
Shukla Triveni P |
Processed meats comprising dietary fiber gel
|
|
US20090142347A1
(en)
|
2004-09-29 |
2009-06-04 |
The Burnham Institute For Medical Research |
Tissue-Nonspecific Alkaline Phosphatase (TNAP): a Therapeutic Target for Arterial Calcification
|
|
WO2006050211A2
(en)
|
2004-10-28 |
2006-05-11 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Peripherally delivered glutamic acid decarboxylase gene therapy for spinal cord injury pain
|
|
EP1813671A4
(en)
|
2004-11-19 |
2008-06-11 |
Ono Pharmaceutical Co |
SOLUBLE PROTEIN AND USE THEREOF
|
|
GB0426397D0
(en)
|
2004-12-01 |
2005-01-05 |
Health Prot Agency |
Fusion proteins
|
|
JP4495210B2
(ja)
|
2005-06-09 |
2010-06-30 |
パナソニック株式会社 |
振幅誤差補償装置及び直交度誤差補償装置
|
|
CA2610159C
(en)
|
2005-06-10 |
2015-03-31 |
Altus Pharmaceuticals Inc. |
Methods to reduce oxalate concentration by administration of oxalate oxidase crystals
|
|
EP1736553A1
(en)
|
2005-06-17 |
2006-12-27 |
Centre National De La Recherche Scientifique |
ENPP1 (PC-1) gene haplotype associated with the risk of obesity and type 2 diabetes and their applications
|
|
US20090180989A1
(en)
|
2005-10-05 |
2009-07-16 |
Synageva Biopharma Corp. |
Compositions and methods for delivering nucleotide sequences to vertebrates
|
|
US11039942B2
(en)
|
2006-06-13 |
2021-06-22 |
Sino Medical Sciences Technology Inc. |
Drug eluting stent and method of use of the same for enabling restoration of functional endothelial cell layers
|
|
PT2046373E
(pt)
|
2006-08-02 |
2013-05-06 |
Althea Technologies Inc |
Oxalato descarboxilase cristalizada e métodos de utilização
|
|
US20100113339A1
(en)
|
2006-09-08 |
2010-05-06 |
Ablynx N. V. |
Serum albumin binding proteins with long half-lives
|
|
WO2008065225A2
(es)
|
2006-11-28 |
2008-06-05 |
Proyecto De Biomedicina Cima, S.L. |
Vector viral y sus aplicaciones
|
|
US20080273206A1
(en)
|
2007-04-23 |
2008-11-06 |
University Of South Carolina |
Biomimetic Mineralization Method and System
|
|
DK2662448T3
(en)
|
2007-05-11 |
2017-03-20 |
Alexion Pharma Inc |
Bone-targeted alkaline phosphatase, kits and methods for its use
|
|
EP2178556B1
(en)
|
2007-06-18 |
2011-08-17 |
Oregon Health & Science University |
Protein c for use in maintaining hemostasis
|
|
WO2009030254A1
(en)
|
2007-09-04 |
2009-03-12 |
Curevac Gmbh |
Complexes of rna and cationic peptides for transfection and for immunostimulation
|
|
GB0803352D0
(en)
|
2008-02-22 |
2008-04-02 |
Ntnu Technology Transfer As |
Oligopeptidic compounds and uses thereof
|
|
AR071885A1
(es)
|
2008-05-23 |
2010-07-21 |
Wyeth Corp |
Proteinas de union al receptor de interleuquina 21
|
|
JP4888439B2
(ja)
|
2008-05-30 |
2012-02-29 |
ブラザー工業株式会社 |
画像読取装置および原稿サイズ決定プログラム
|
|
WO2011097456A2
(en)
|
2010-02-05 |
2011-08-11 |
The University Of North Carolina At Chapel Hill |
Compositions and methods for enhanced parvovirus transduction
|
|
EP2545080B1
(en)
|
2010-03-12 |
2017-05-10 |
Alexion Pharmaceuticals, Inc. |
Npp1 fusion proteins
|
|
EP2683742B1
(en)
|
2011-03-11 |
2018-12-19 |
Alexion Pharmaceuticals, Inc. |
Npp1 fusion proteins
|
|
WO2012130567A1
(en)
|
2011-03-29 |
2012-10-04 |
Beta-Cell Nv |
Method for encapsulated therapeutic products and uses thereof
|
|
WO2013074615A1
(en)
|
2011-11-14 |
2013-05-23 |
Yale University |
Compositions and methods for modulating coagulation
|
|
AU2014204045B2
(en)
|
2013-01-04 |
2018-10-18 |
Rempex Pharmaceuticals, Inc. |
Boronic acid derivatives and therapeutic uses thereof
|
|
PL2956163T3
(pl)
|
2013-02-13 |
2025-04-14 |
Yale University |
Kompozycje do leczenia patologicznego zwapnienia i kostnienia
|
|
WO2014152940A1
(en)
|
2013-03-14 |
2014-09-25 |
Shire Human Genetic Therapies, Inc. |
Mrna therapeutic compositions and use to treat diseases and disorders
|
|
CN114717206A
(zh)
|
2013-03-15 |
2022-07-08 |
Atyr 医药公司 |
组氨酰-trna合成酶-fc缀合物
|
|
ES2523016B1
(es)
|
2013-05-20 |
2015-09-09 |
3P Biopharmaceuticals |
Vectores alfavirales y líneas celulares para la producción de proteínas recombinantes
|
|
CA2920856C
(en)
|
2013-08-09 |
2026-03-03 |
Ardelyx, Inc. |
Ph modulating compounds for inhibiting gastrointestinal phosphate uptake
|
|
CA2924259C
(en)
|
2013-09-19 |
2021-12-21 |
Universitatsspital Basel |
Artificial vascular graft
|
|
AU2015219339B2
(en)
|
2014-02-19 |
2020-03-05 |
Bioasis Technologies Inc. |
P97-IDS fusion proteins
|
|
GB2526339A
(en)
|
2014-05-21 |
2015-11-25 |
Imp Innovations Ltd |
Lentiviral vectors
|
|
US10973931B2
(en)
|
2014-09-16 |
2021-04-13 |
Universitat Autònoma De Barcelona |
Adeno-associated viral vectors for the gene therapy of metabolic diseases
|
|
HK1245662A1
(zh)
|
2014-12-19 |
2018-08-31 |
Alexion Pharmaceuticals, Inc. |
治疗组织钙化的方法
|
|
US10926006B2
(en)
|
2015-02-26 |
2021-02-23 |
Remodeless Cv Ltd |
Drug eluting stent
|
|
EP3298140B1
(en)
|
2015-05-19 |
2024-04-24 |
Yale University |
Compositions for treating pathological calcification conditions, and methods using same
|
|
TN2018000163A1
(en)
|
2015-11-12 |
2019-10-04 |
Res Inst Nationwide Childrens Hospital |
Methods of treating muscular dystrophy
|
|
EP3377105A4
(en)
*
|
2015-11-20 |
2019-04-24 |
Yale University |
COMPOSITIONS FOR THE TREATMENT OF ECTOPIC CALIBRATION DISORDERS AND METHODS THEREWITH
|
|
WO2017191274A2
(en)
|
2016-05-04 |
2017-11-09 |
Curevac Ag |
Rna encoding a therapeutic protein
|
|
EP3471747A1
(en)
*
|
2016-06-16 |
2019-04-24 |
Alexion Pharmaceuticals, Inc. |
Methods of treating myointimal proliferation
|
|
US11390859B2
(en)
|
2016-08-05 |
2022-07-19 |
Yale University |
Compositions and methods for stroke prevention in pediatric sickle cell anemia patients
|
|
IL268198B2
(en)
|
2017-02-27 |
2024-10-01 |
Shattuck Labs Inc |
Tigit- and light-based chimeric proteins
|
|
US12134790B2
(en)
|
2017-09-27 |
2024-11-05 |
Inozyme Pharma, Inc. |
Methods of improving cardiovascular function and treating cardiovascular disease using a recombinant ectonucleotide pyrophosphatase phosphodiesterase (NPP1)
|
|
JP2021523139A
(ja)
|
2018-05-08 |
2021-09-02 |
イエール ユニバーシティ |
腎石症の進行を遅らせるための組成物および方法
|