JP2020532285A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020532285A5 JP2020532285A5 JP2020500686A JP2020500686A JP2020532285A5 JP 2020532285 A5 JP2020532285 A5 JP 2020532285A5 JP 2020500686 A JP2020500686 A JP 2020500686A JP 2020500686 A JP2020500686 A JP 2020500686A JP 2020532285 A5 JP2020532285 A5 JP 2020532285A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- amino acid
- fusion protein
- polypeptide
- nos
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023085796A JP2023120208A (ja) | 2017-07-11 | 2023-05-24 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
| JP2025044077A JP2025118590A (ja) | 2017-07-11 | 2025-03-18 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762531215P | 2017-07-11 | 2017-07-11 | |
| US62/531,215 | 2017-07-11 | ||
| PCT/US2018/041661 WO2019014360A1 (en) | 2017-07-11 | 2018-07-11 | POLYPEPTIDES BINDING COMPONENT C5 OR SERUM ALBUMIN COMPONENT AND FUSION PROTEINS THEREOF |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023085796A Division JP2023120208A (ja) | 2017-07-11 | 2023-05-24 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020532285A JP2020532285A (ja) | 2020-11-12 |
| JP2020532285A5 true JP2020532285A5 (enExample) | 2021-11-25 |
| JP7684803B2 JP7684803B2 (ja) | 2025-05-28 |
Family
ID=63036501
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020500686A Active JP7684803B2 (ja) | 2017-07-11 | 2018-07-11 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
| JP2023085796A Pending JP2023120208A (ja) | 2017-07-11 | 2023-05-24 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
| JP2025044077A Pending JP2025118590A (ja) | 2017-07-11 | 2025-03-18 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023085796A Pending JP2023120208A (ja) | 2017-07-11 | 2023-05-24 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
| JP2025044077A Pending JP2025118590A (ja) | 2017-07-11 | 2025-03-18 | 補体成分ｃ５または血清アルブミンと結合するポリペプチドおよびその融合タンパク質 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US11498960B2 (enExample) |
| EP (1) | EP3625265A1 (enExample) |
| JP (3) | JP7684803B2 (enExample) |
| KR (3) | KR102806328B1 (enExample) |
| CN (3) | CN111201246B (enExample) |
| AU (3) | AU2018301412B2 (enExample) |
| BR (1) | BR112019028269A2 (enExample) |
| CA (1) | CA3067247A1 (enExample) |
| CO (1) | CO2020000369A2 (enExample) |
| IL (3) | IL307197B2 (enExample) |
| MX (2) | MX2024005945A (enExample) |
| WO (1) | WO2019014360A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102806328B1 (ko) | 2017-07-11 | 2025-05-14 | 알렉시온 파마슈티칼스, 인코포레이티드 | 보체 성분 c5 또는 혈청 알부민에 결합하는 폴리펩티드 및 그의 융합 단백질 |
| US20210388070A1 (en) * | 2018-10-30 | 2021-12-16 | Alexion Pharmaceuticals, Inc. | Co-administration of a hyaluronidase and anti-c5 antibody for treatment of complement-associated conditions |
| EP3956344A1 (en) * | 2019-04-16 | 2022-02-23 | University of Washington | Amantadine binding protein |
| TWI844709B (zh) | 2019-07-31 | 2024-06-11 | 美商美國禮來大藥廠 | 鬆弛素(relaxin)類似物及其使用方法 |
| BR112022010742A2 (pt) | 2019-12-26 | 2022-08-16 | Eisai R&D Man Co Ltd | Composição farmacêutica contendo ácido ribonucleico de fita dupla que inibe a expressão de c5 complementar |
| JP7343618B2 (ja) | 2020-01-17 | 2023-09-12 | オリンパス株式会社 | 発光装置、および駆動装置 |
| EP4135837A1 (en) | 2020-04-16 | 2023-02-22 | Assistance Publique, Hopitaux De Paris | Methods for treating a complement mediated disorder caused by viruses |
| IL301713A (en) * | 2020-10-05 | 2023-05-01 | Alexion Pharma Inc | Methods for treating dermatomyositis |
| CN120018862A (zh) * | 2022-08-31 | 2025-05-16 | 阿雷克森制药公司 | 用于治疗镰状细胞病的融合多肽的剂量和施用 |
| CN116731149B (zh) * | 2023-06-07 | 2024-02-27 | 华中农业大学 | 草鱼补体活化分子碳末端肽C5a-CP及应用 |
| CN119241699B (zh) * | 2024-09-24 | 2025-11-28 | 广州康盛生物科技股份有限公司 | 一种抗人补体c5的单域抗体及其应用 |
| CN121518561A (zh) * | 2025-12-24 | 2026-02-13 | 北京林业大学 | 一种PagRAP2.3蛋白点突变及其在植物愈伤再生中的应用 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| DK1621554T4 (da) | 1992-08-21 | 2012-12-17 | Univ Bruxelles | Immunoglobuliner blottet for lette kæder |
| EP0739981A1 (en) | 1995-04-25 | 1996-10-30 | Vrije Universiteit Brussel | Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes |
| ES2294799T3 (es) | 1996-06-27 | 2008-04-01 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw. | Moleculas de anticuerpos que interactuan especificamente con el sitio activo o hendidura de una molecula diana. |
| DK1027439T3 (da) | 1997-10-27 | 2010-05-10 | Bac Ip Bv | Multivalente antigenbindende proteiner |
| EP1240337B1 (en) | 1999-12-24 | 2006-08-23 | Genentech, Inc. | Methods and compositions for prolonging elimination half-times of bioactive compounds |
| US7083784B2 (en) * | 2000-12-12 | 2006-08-01 | Medimmune, Inc. | Molecules with extended half-lives, compositions and uses thereof |
| AU2002335930B2 (en) | 2001-03-09 | 2005-07-28 | Morphosys Ag | Serum albumin binding moieties |
| AU2003210060B2 (en) | 2002-03-22 | 2010-02-25 | Aprogen, Inc. | Humanized antibody and process for preparing same |
| WO2004041863A2 (en) | 2002-11-08 | 2004-05-21 | Ablynx N.V. | Single domain antibodies directed against interferon- gamma and uses therefor |
| EP1558645B1 (en) * | 2002-11-08 | 2011-07-27 | Ablynx N.V. | Stabilized single domain antibodies in pharmaceutical composition adapted for inhalation |
| JP2006517789A (ja) | 2003-01-10 | 2006-08-03 | アブリンクス エン．ヴェー． | 治療用ポリペプチド、その相同物、その断片、および血小板媒介凝集の調節での使用 |
| AU2012254935B2 (en) * | 2004-02-12 | 2014-05-29 | Archemix Llc | Aptamer Therapeutics Useful in the Treatment of Complement-Related Disorders |
| TW200607523A (en) * | 2004-06-01 | 2006-03-01 | Domantis Ltd | Drug compositions, fusions and conjugates |
| US7423128B2 (en) | 2004-11-03 | 2008-09-09 | Amgen Fremont Inc. | Anti-properdin antibodies, and methods for making and using same |
| CN100368022C (zh) | 2005-09-20 | 2008-02-13 | 中国人民解放军第二军医大学 | 双重靶向抗肝纤维化药物载体拟糖蛋白纳米粒及其制法 |
| US7807409B2 (en) * | 2005-10-21 | 2010-10-05 | Roche Palo Alto Llc | Method for the recombinant expression of a polypeptide |
| SG10201804008UA (en) | 2005-11-04 | 2018-06-28 | Genentech Inc | Use of complement pathway inhibitors to treat ocular diseases |
| DK2262831T3 (en) | 2008-03-03 | 2015-04-27 | Novelmed Therapeutics Inc | ANTI-Properdin ANTIBODIES |
| PY09026846A (es) * | 2008-08-05 | 2015-09-01 | Novartis Ag | Composiciones y métodos para anticuerpos que se dirigen a la proteína de complemento c5 |
| CA2766565A1 (en) * | 2009-06-23 | 2010-12-29 | Alexion Pharmaceuticals, Inc. | Bispecific antibodies that bind to complement proteins |
| EP2478110B1 (en) | 2009-09-16 | 2016-01-06 | Immunomedics, Inc. | Class i anti-cea antibodies and uses thereof |
| WO2011064382A1 (en) | 2009-11-30 | 2011-06-03 | Ablynx N.V. | Improved amino acid sequences directed against human respiratory syncytial virus (hrsv) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections |
| EP2531523A1 (en) * | 2010-02-05 | 2012-12-12 | Ablynx N.V. | Peptides capable of binding to serum albumin and compounds, constructs and polypeptides comprising the same |
| CA2811221C (en) | 2010-03-10 | 2018-01-09 | Novelmed Therapeutics, Inc. | Humanized and chimeric anti-properdin antibodies |
| TW201138808A (en) * | 2010-05-03 | 2011-11-16 | Bristol Myers Squibb Co | Serum albumin binding molecules |
| CN103003296A (zh) | 2010-07-09 | 2013-03-27 | 阿菲博迪公司 | 多肽 |
| TW201241008A (en) | 2010-10-01 | 2012-10-16 | Alexion Pharma Inc | Polypeptides that bind to human complement component C5 |
| KR20140064768A (ko) | 2011-07-01 | 2014-05-28 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 항-프로퍼딘 항체 및 그의 용도 |
| ES2728278T3 (es) | 2011-12-21 | 2019-10-23 | Novartis Ag | Composiciones que comprenden anticuerpos dirigidos al factor P y C5 |
| WO2013102123A2 (en) | 2011-12-28 | 2013-07-04 | Novelmed Therapeutics, Inc. | Aglycosylated human antibody and fusion protein and uses thereof |
| EP3511339B1 (en) | 2012-02-20 | 2025-04-09 | IPC Research, LLC | Polypeptides binding to human complement c5 |
| CA2887050A1 (en) | 2012-10-04 | 2014-04-10 | Novelmed Therapeutics, Inc. | Alternative pathway specific antibodies for treating hemolytic diseases |
| BR112016003142A2 (pt) | 2013-08-28 | 2017-10-17 | Swedish Orphan Biovitrum Ab Publ | ligação de polipeptídeos estáveis ao c5 do complemento humano |
| MX367423B (es) | 2013-08-28 | 2019-08-21 | Affibody Ab | Polipeptidos de union a c5. |
| NZ631007A (en) * | 2014-03-07 | 2015-10-30 | Alexion Pharma Inc | Anti-c5 antibodies having improved pharmacokinetics |
| MX2019008827A (es) | 2017-01-30 | 2019-09-26 | Alexion Pharma Inc | Anticuerpos anti-properdina monovalentes y fragmentos de anticuerpo. |
| KR102806328B1 (ko) | 2017-07-11 | 2025-05-14 | 알렉시온 파마슈티칼스, 인코포레이티드 | 보체 성분 c5 또는 혈청 알부민에 결합하는 폴리펩티드 및 그의 융합 단백질 |
-
2018
- 2018-07-11 KR KR1020207002889A patent/KR102806328B1/ko active Active
- 2018-07-11 CN CN201880046102.3A patent/CN111201246B/zh active Active
- 2018-07-11 EP EP18746529.9A patent/EP3625265A1/en active Pending
- 2018-07-11 IL IL307197A patent/IL307197B2/en unknown
- 2018-07-11 JP JP2020500686A patent/JP7684803B2/ja active Active
- 2018-07-11 CA CA3067247A patent/CA3067247A1/en active Pending
- 2018-07-11 AU AU2018301412A patent/AU2018301412B2/en active Active
- 2018-07-11 BR BR112019028269-6A patent/BR112019028269A2/pt unknown
- 2018-07-11 KR KR1020257014994A patent/KR20250068795A/ko active Pending
- 2018-07-11 KR KR1020257021037A patent/KR20250099285A/ko active Pending
- 2018-07-11 CN CN202311281093.5A patent/CN117327187A/zh active Pending
- 2018-07-11 US US16/629,687 patent/US11498960B2/en active Active
- 2018-07-11 WO PCT/US2018/041661 patent/WO2019014360A1/en not_active Ceased
- 2018-07-11 CN CN202311281139.3A patent/CN117327188A/zh active Pending
- 2018-07-11 IL IL271920A patent/IL271920B2/en unknown
-
2020
- 2020-01-08 MX MX2024005945A patent/MX2024005945A/es unknown
- 2020-01-08 MX MX2024005946A patent/MX2024005946A/es unknown
- 2020-01-15 CO CONC2020/0000369A patent/CO2020000369A2/es unknown
-
2022
- 2022-10-07 US US17/938,756 patent/US12221473B2/en active Active
-
2023
- 2023-05-24 JP JP2023085796A patent/JP2023120208A/ja active Pending
-
2025
- 2025-01-02 US US19/007,782 patent/US20250163138A1/en active Pending
- 2025-01-16 AU AU2025200303A patent/AU2025200303A1/en active Pending
- 2025-01-16 AU AU2025200313A patent/AU2025200313A1/en active Pending
- 2025-03-18 JP JP2025044077A patent/JP2025118590A/ja active Pending
- 2025-10-21 IL IL324119A patent/IL324119A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020532285A5 (enExample) | ||
| JP2023120208A5 (enExample) | ||
| JP2024063213A5 (enExample) | ||
| AU2016351710B2 (en) | Improved serum albumin-binding immunoglobulin variable domains | |
| DK2443137T3 (en) | NOVEL chemokine-binding peptides capable of impeding the sequence for immunity, inflammation and cancer | |
| EP2847229B1 (en) | Single domain binding molecule | |
| JP2023506765A5 (enExample) | ||
| JP2020501550A5 (enExample) | ||
| WO2018233574A1 (zh) | 一种抗pd-l1人源化纳米抗体及其应用 | |
| RU2015141418A (ru) | Антитела, связывающие il-4 и/или il-13, и их применение | |
| CN114380906B (zh) | 一种抗il-17a的单域抗体及其用途 | |
| JP2020504759A (ja) | Ｓ．ａｕｒｅｕｓ溶血素ａ毒素に対するヒト抗体 | |
| JP2023505492A5 (enExample) | ||
| CN113966343A (zh) | 结合PcrV的抗PcrV抗体、包含抗PcrV抗体的组合物及其使用方法 | |
| CN101378781B (zh) | 制造免疫球蛋白的组合物和方法 | |
| JP2020535811A5 (enExample) | ||
| JP2024023268A5 (enExample) | ||
| CN112390884B (zh) | Semaphorin7A单克隆抗体及其在制备用于治疗炎症疾病药物方面的应用 | |
| CN114591432B (zh) | 抗TNFα的单域抗体及其用途 | |
| WO2022011717A1 (zh) | 针对新型冠状病毒的纳米抗体及其应用 | |
| JP7796414B2 (ja) | Ｃｌｅｃ１２ａ抗体断片配列及び方法 | |
| CN117860786B (zh) | 基因修饰间充质干细胞在多种疾病中的制药用途和诊断用途 | |
| CN117843777B (zh) | 用于炎性疾病治疗的新型纳米抗体及其产品和方法 | |
| JP2024546916A5 (enExample) | ||
| JPH0213376A (ja) | 緑膿菌に対するモノクローナル抗体、ならびにその調製および使用 |