JP2023113636A5 - - Google Patents
Info
- Publication number
- JP2023113636A5 JP2023113636A5 JP2023077286A JP2023077286A JP2023113636A5 JP 2023113636 A5 JP2023113636 A5 JP 2023113636A5 JP 2023077286 A JP2023077286 A JP 2023077286A JP 2023077286 A JP2023077286 A JP 2023077286A JP 2023113636 A5 JP2023113636 A5 JP 2023113636A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody polypeptide
- polypeptide
- single variable
- variable domain
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762511245P | 2017-05-25 | 2017-05-25 | |
| US62/511,245 | 2017-05-25 | ||
| PCT/US2018/034330 WO2018217988A1 (en) | 2017-05-25 | 2018-05-24 | MODIFIED IgG1 Fc DOMAINS AND ANTI-CD40 DOMAIN ANTIBODY FUSIONS THEREWITH |
| JP2019564951A JP2020521458A (ja) | 2017-05-25 | 2018-05-24 | 改変ＩｇＧ１ Ｆｃドメインおよび該ドメインと抗ＣＤ４０ドメイン抗体の融合物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019564951A Division JP2020521458A (ja) | 2017-05-25 | 2018-05-24 | 改変ＩｇＧ１ Ｆｃドメインおよび該ドメインと抗ＣＤ４０ドメイン抗体の融合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023113636A JP2023113636A (ja) | 2023-08-16 |
| JP2023113636A5 true JP2023113636A5 (enExample) | 2025-11-28 |
Family
ID=62599725
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019564951A Pending JP2020521458A (ja) | 2017-05-25 | 2018-05-24 | 改変ＩｇＧ１ Ｆｃドメインおよび該ドメインと抗ＣＤ４０ドメイン抗体の融合物 |
| JP2023077286A Pending JP2023113636A (ja) | 2017-05-25 | 2023-05-09 | 改変ＩｇＧ１ Ｆｃドメインおよび該ドメインと抗ＣＤ４０ドメイン抗体の融合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019564951A Pending JP2020521458A (ja) | 2017-05-25 | 2018-05-24 | 改変ＩｇＧ１ Ｆｃドメインおよび該ドメインと抗ＣＤ４０ドメイン抗体の融合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20200148779A1 (enExample) |
| EP (1) | EP3630832A1 (enExample) |
| JP (2) | JP2020521458A (enExample) |
| KR (2) | KR102847736B1 (enExample) |
| CN (1) | CN110637035A (enExample) |
| WO (1) | WO2018217988A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230125855A (ko) | 2014-11-21 | 2023-08-29 | 브리스톨-마이어스 스큅 컴퍼니 | Cd73에 대항한 항체 및 그의 용도 |
| FI3468997T3 (fi) | 2016-06-08 | 2023-10-31 | Xencor Inc | Igg4:ään liittyvien sairauksien hoito anti-cd19-vasta-aineilla, jotka ristisitoutuvat cd32b:een |
| CN110621697B (zh) | 2017-05-25 | 2023-06-27 | 百时美施贵宝公司 | 拮抗性cd40单克隆抗体及其用途 |
| EA202092302A1 (ru) | 2018-04-02 | 2021-02-02 | Бристол-Майерс Сквибб Компани | Антитела к trem-1 и их применения |
| AR117091A1 (es) | 2018-11-19 | 2021-07-07 | Bristol Myers Squibb Co | Anticuerpos monoclonales antagonistas contra cd40 y sus usos |
| JP7762645B2 (ja) * | 2019-08-22 | 2025-10-30 | シダラ セラピューティクス インコーポレーテッド | バリアントｆｃドメイン及びその使用 |
| TWI869528B (zh) | 2020-01-13 | 2025-01-11 | 美商威特拉公司 | C5ar1抗體分子及其用途 |
| KR20220151189A (ko) * | 2020-03-09 | 2022-11-14 | 브리스톨-마이어스 스큅 컴퍼니 | 증진된 효능제 활성을 갖는 cd40에 대한 항체 |
| CN115443147A (zh) * | 2020-04-23 | 2022-12-06 | 伊莱利利公司 | 抗体的皮下吸收和生物利用度 |
| JP7523586B2 (ja) | 2020-05-18 | 2024-07-26 | ブリストル－マイヤーズ スクイブ カンパニー | 改善された薬物動態特性を有する抗体変異体 |
| CN112552389B (zh) * | 2020-08-07 | 2023-06-06 | 中爱瑞祥(杭州)生物科技有限公司 | 一种活性肽融合蛋白及其制备方法 |
| CA3196766A1 (en) * | 2020-11-02 | 2022-05-05 | Attralus, Inc. | Sap fc fusion proteins and methods of use |
| TW202246331A (zh) | 2021-01-13 | 2022-12-01 | 美商威特拉公司 | 人源化補體５ａ受體１抗體及其使用方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040132101A1 (en) * | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
| US9051373B2 (en) * | 2003-05-02 | 2015-06-09 | Xencor, Inc. | Optimized Fc variants |
| DK2471813T3 (en) * | 2004-07-15 | 2015-03-02 | Xencor Inc | Optimized Fc variants |
| CN101331223A (zh) * | 2005-10-14 | 2008-12-24 | 米迪缪尼有限公司 | 细胞展示抗体文库 |
| US10053513B2 (en) * | 2009-11-30 | 2018-08-21 | Janssen Biotech, Inc. | Antibody Fc mutants with ablated effector functions |
| AR083847A1 (es) * | 2010-11-15 | 2013-03-27 | Novartis Ag | Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40 |
| TWI598363B (zh) * | 2011-04-21 | 2017-09-11 | 必治妥美雅史谷比公司 | 拮抗ｃｄ４０之抗體多肽 |
| US20140294812A1 (en) * | 2013-03-15 | 2014-10-02 | Xencor, Inc. | Fc variants that improve fcrn binding and/or increase antibody half-life |
| US10435475B2 (en) * | 2014-03-07 | 2019-10-08 | Bristol-Myers Squibb Company | Method of using antibody polypeptides that antagonize CD40 to treat IBD |
| US20170233485A1 (en) * | 2014-08-18 | 2017-08-17 | Biogen Ma Inc. | Anti-cd40 antibodies and uses thereof |
| MA43053A (fr) * | 2015-09-30 | 2018-08-08 | Janssen Biotech Inc | Anticorps antagonistes se liant spécifiquement au cd40 humain et procédés d'utilisation |
| CN110621697B (zh) * | 2017-05-25 | 2023-06-27 | 百时美施贵宝公司 | 拮抗性cd40单克隆抗体及其用途 |
-
2018
- 2018-05-24 EP EP18731284.8A patent/EP3630832A1/en active Pending
- 2018-05-24 KR KR1020247019564A patent/KR102847736B1/ko active Active
- 2018-05-24 KR KR1020197037759A patent/KR20200012907A/ko not_active Ceased
- 2018-05-24 US US16/495,994 patent/US20200148779A1/en active Pending
- 2018-05-24 JP JP2019564951A patent/JP2020521458A/ja active Pending
- 2018-05-24 CN CN201880032964.0A patent/CN110637035A/zh active Pending
- 2018-05-24 WO PCT/US2018/034330 patent/WO2018217988A1/en not_active Ceased
-
2023
- 2023-05-09 JP JP2023077286A patent/JP2023113636A/ja active Pending
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