|
US4036945A
(en)
|
1976-05-03 |
1977-07-19 |
The Massachusetts General Hospital |
Composition and method for determining the size and location of myocardial infarcts
|
|
US4458066A
(en)
|
1980-02-29 |
1984-07-03 |
University Patents, Inc. |
Process for preparing polynucleotides
|
|
US4331647A
(en)
|
1980-03-03 |
1982-05-25 |
Goldenberg Milton David |
Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
|
|
US4485045A
(en)
|
1981-07-06 |
1984-11-27 |
Research Corporation |
Synthetic phosphatidyl cholines useful in forming liposomes
|
|
US4722848A
(en)
|
1982-12-08 |
1988-02-02 |
Health Research, Incorporated |
Method for immunizing animals with synthetically modified vaccinia virus
|
|
US4544545A
(en)
|
1983-06-20 |
1985-10-01 |
Trustees University Of Massachusetts |
Liposomes containing modified cholesterol for organ targeting
|
|
US5981216A
(en)
|
1985-04-01 |
1999-11-09 |
Alusuisse Holdings A.G. |
Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
|
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
GB8717430D0
(en)
|
1987-07-23 |
1987-08-26 |
Celltech Ltd |
Recombinant dna product
|
|
CA1323293C
(en)
|
1987-12-11 |
1993-10-19 |
Keith C. Backman |
Assay using template-dependent nucleic acid probe reorganization
|
|
ATE138106T1
(de)
|
1988-07-20 |
1996-06-15 |
David Segev |
Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
IT1231156B
(it)
|
1989-07-19 |
1991-11-19 |
Eniricerche Spa |
Espressione e secrezione di interleuchina 1 beta umana matura in bacillus subtilis e mezzi e metodi per il suo ottenimento.
|
|
US5013556A
(en)
|
1989-10-20 |
1991-05-07 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US5427930A
(en)
|
1990-01-26 |
1995-06-27 |
Abbott Laboratories |
Amplification of target nucleic acids using gap filling ligase chain reaction
|
|
US5643578A
(en)
|
1992-03-23 |
1997-07-01 |
University Of Massachusetts Medical Center |
Immunization by inoculation of DNA transcription unit
|
|
EP0671926B1
(en)
|
1992-08-11 |
2002-11-13 |
President And Fellows Of Harvard College |
Immunomodulatory peptides
|
|
US5593972A
(en)
|
1993-01-26 |
1997-01-14 |
The Wistar Institute |
Genetic immunization
|
|
US5648211A
(en)
|
1994-04-18 |
1997-07-15 |
Becton, Dickinson And Company |
Strand displacement amplification using thermophilic enzymes
|
|
ES2168380T3
(es)
|
1994-07-15 |
2002-06-16 |
Organon Teknika Bv |
Utilizacion de arn polimerasa para mejorar un procedimiento de amplificacion de acido nucleico.
|
|
AT402203B
(de)
|
1995-06-13 |
1997-03-25 |
Himmler Gottfried Dipl Ing Dr |
Verfahren zur transkriptionsfreien amplifizierung von nucleinsäuren
|
|
US6100388A
(en)
|
1998-03-16 |
2000-08-08 |
Biogaia Biologies Ab |
Lactobacilli harboring aggregation gene as a vaccine delivery vehicle
|
|
ES2252261T3
(es)
|
2000-06-28 |
2006-05-16 |
Glycofi, Inc. |
Metodos para producir glicoproteinas modificadas.
|
|
US7282205B2
(en)
|
2001-11-07 |
2007-10-16 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Anti-hepatitis A virus antibodies
|
|
MXPA06004035A
(es)
|
2003-10-16 |
2006-08-31 |
Micromet Ag |
Aglutinantes cd3 de-inmunizados multi-especificos.
|
|
EP1697520A2
(en)
|
2003-12-22 |
2006-09-06 |
Xencor, Inc. |
Fc polypeptides with novel fc ligand binding sites
|
|
JP2009526520A
(ja)
|
2006-01-17 |
2009-07-23 |
バイオレックス セラピュティックス インク |
植物中でのn−グリカンのヒト化及び最適化のための組成物及び方法
|
|
WO2007146957A2
(en)
|
2006-06-13 |
2007-12-21 |
Irm Llc |
Ror1 as a therapeutic target for lung cancer
|
|
AU2008204442B2
(en)
|
2007-01-12 |
2013-03-14 |
Intrexon Actobiotics Nv |
Lactococcus promoters and uses thereof
|
|
EP1995309A1
(en)
|
2007-05-21 |
2008-11-26 |
Vivalis |
Recombinant protein production in avian EBx® cells
|
|
CA2759733C
(en)
|
2009-04-23 |
2019-09-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-human ror1 antibodies
|
|
WO2011054007A1
(en)
|
2009-11-02 |
2011-05-05 |
Oxford Biotherapeutics Ltd. |
Ror1 as therapeutic and diagnostic target
|
|
US9150647B2
(en)
|
2009-12-18 |
2015-10-06 |
Kancera Ab |
Biological inhibitors of ROR1 capable of inducing cell death
|
|
EP3828205A1
(en)
|
2010-10-01 |
2021-06-02 |
Oxford BioTherapeutics Ltd |
Anti-ror1 antibodies
|
|
ES2657970T3
(es)
|
2010-12-01 |
2018-03-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anticuerpos contra ROR1 de conejo/ser humano quiméricos
|
|
GB201020995D0
(en)
|
2010-12-10 |
2011-01-26 |
Bioinvent Int Ab |
Biological materials and uses thereof
|
|
EP3604339B1
(en)
|
2011-01-14 |
2021-03-10 |
The Regents Of The University Of California |
Therapeutic antibodies against ror-1 protein and methods for use of same
|
|
BR122020002986A8
(pt)
|
2012-08-20 |
2023-04-18 |
Seattle Childrens Hospital Dba Seattle Childrens Res Inst |
Método e composições para imunoterapia celular
|
|
ES2702315T3
(es)
*
|
2012-08-24 |
2019-02-28 |
Univ California |
Anticuerpos y vacunas para su uso en tratar cánceres ROR1 e inhibir metástasis
|
|
CN105283201B
(zh)
*
|
2013-03-14 |
2019-08-02 |
斯克利普斯研究所 |
靶向剂抗体偶联物及其用途
|
|
EP2789630A1
(en)
*
|
2013-04-09 |
2014-10-15 |
EngMab AG |
Bispecific antibodies against CD3e and ROR1
|
|
WO2015006749A2
(en)
*
|
2013-07-12 |
2015-01-15 |
Zymeworks Inc. |
Bispecific cd3 and cd19 antigen binding contructs
|
|
EA035419B9
(ru)
|
2014-05-29 |
2020-08-07 |
Мэкроудженикс, Инк. |
Триспецифичные связывающие молекулы и способы их применения
|
|
WO2016016344A1
(en)
*
|
2014-07-29 |
2016-02-04 |
Cellectis |
Ror1(ntrkr1)specific chimeric antigen receptors for cancer immunotherapy
|
|
US10544201B2
(en)
|
2014-07-31 |
2020-01-28 |
Cellectis |
ROR1 specific multi-chain chimeric antigen receptor
|
|
WO2016039321A1
(ja)
|
2014-09-08 |
2016-03-17 |
国立研究開発法人国立がん研究センター |
がん細胞特異的な抗体、抗がん剤、及びがんの検査方法
|
|
CA2963696A1
(en)
|
2014-10-09 |
2016-04-14 |
Engmab Ag |
Bispecific antibodies against cd3epsilon and ror1 for use in the treatment of ovarian cancer
|
|
EP3204415B1
(en)
|
2014-10-09 |
2020-06-17 |
EngMab Sàrl |
Bispecific antibodies against cd3epsilon and ror1
|
|
WO2016094873A2
(en)
|
2014-12-12 |
2016-06-16 |
Emergent Product Development Seattle, Llc |
Receptor tyrosine kinase-like orphan receptor 1 binding proteins and related compositions and methods
|
|
ES2818103T3
(es)
|
2015-01-16 |
2021-04-09 |
Juno Therapeutics Inc |
Anticuerpos y receptores de antígenos quiméricos específicos para ROR1
|
|
CN107567445B
(zh)
|
2015-02-02 |
2021-06-29 |
坎塞拉有限公司 |
可用作哺乳动物酪氨酸激酶ror1活性抑制剂的2-苯基-3h-咪唑并[4,5-b]吡啶衍生物
|
|
WO2016187220A2
(en)
|
2015-05-18 |
2016-11-24 |
Five Prime Therapeutics, Inc. |
Anti-ror1 antibodies
|
|
WO2016187216A1
(en)
|
2015-05-18 |
2016-11-24 |
Bluebird Bio, Inc. |
Anti-ror1 chimeric antigen receptors
|
|
SG11201803098VA
(en)
|
2015-10-30 |
2018-05-30 |
Nbe Therapeutics Ag |
Anti-ror1 antibodies
|
|
UA125718C2
(uk)
|
2016-01-20 |
2022-05-25 |
Зе Скріппс Ресеарч Інстітьют |
Композиції антитіл до ror1 і пов'язані з ними способи
|
|
TW201734049A
(zh)
|
2016-01-22 |
2017-10-01 |
健生生物科技公司 |
抗-ror1抗體、ror1 x cd3雙特異性抗體及使用其之方法
|
|
WO2017142928A1
(en)
|
2016-02-17 |
2017-08-24 |
Macrogenics, Inc. |
Ror1-binding molecules, and methods of use thereof
|
|
WO2017156479A1
(en)
|
2016-03-11 |
2017-09-14 |
Bluebird Bio, Inc. |
Ror1 chimeric antigen receptors
|
|
EP3481824B1
(en)
|
2016-07-11 |
2021-10-20 |
Kancera AB |
2-phenylimidazo[4,5-b]pyridin-7-amine derivates useful as inhibitors of mammalian tyrosine kinase ror1 activity
|
|
US20200338210A1
(en)
|
2016-12-22 |
2020-10-29 |
Ardeagen Corporation |
Anti-ror1 antibody and conjugates thereof
|
|
JP2020521448A
(ja)
|
2017-05-23 |
2020-07-27 |
ドラゴンフライ セラピューティクス, インコーポレイテッド |
Nkg2d、cd16、およびror1またはror2に結合するタンパク質
|
|
AU2018289581C1
(en)
|
2017-06-23 |
2025-01-30 |
VelosBio Inc. |
ROR1 antibody immunoconjugates
|
|
US11987635B2
(en)
|
2017-06-25 |
2024-05-21 |
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd. |
Anti-4-1BB antibodies and methods of making and using thereof
|
|
US20210139579A1
(en)
|
2017-07-20 |
2021-05-13 |
Nbe-Therapeutics Ag |
Multispecific antibody product that binds to different ror1 epitopes
|
|
KR20230008269A
(ko)
|
2017-08-07 |
2023-01-13 |
엔비이-테라퓨틱스 아게 |
생체 내 내성이 높은 항체 약물 결합체
|
|
EP3703711A4
(en)
|
2017-11-03 |
2021-01-13 |
Lentigen Technology, Inc. |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER WITH ANTI-MMR1 IMMUNOTHERAPY
|
|
GB201721802D0
(en)
|
2017-12-22 |
2018-02-07 |
Almac Discovery Ltd |
Ror1-specific antigen binding molecules
|
|
WO2019225777A1
(ko)
|
2018-05-23 |
2019-11-28 |
에이비엘바이오 주식회사 |
항-ror1 항체 및 그 용도
|