JP2020524497A5 - - Google Patents

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JP2020524497A5
JP2020524497A5 JP2019567686A JP2019567686A JP2020524497A5 JP 2020524497 A5 JP2020524497 A5 JP 2020524497A5 JP 2019567686 A JP2019567686 A JP 2019567686A JP 2019567686 A JP2019567686 A JP 2019567686A JP 2020524497 A5 JP2020524497 A5 JP 2020524497A5
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polypeptide
amino acid
polypeptide comprises
target
acid substitution
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JP7518620B2 (ja
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JP2019567686A 2017-06-09 2018-06-08 操作されたcas9ヌクレアーゼ Active JP7518620B2 (ja)

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US201762517811P 2017-06-09 2017-06-09
US62/517,811 2017-06-09
US201862665388P 2018-05-01 2018-05-01
US62/665,388 2018-05-01
PCT/US2018/036695 WO2018227114A1 (en) 2017-06-09 2018-06-08 Engineered cas9 nucleases

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JP2020524497A JP2020524497A (ja) 2020-08-20
JP2020524497A5 true JP2020524497A5 (enExample) 2021-07-26
JP7518620B2 JP7518620B2 (ja) 2024-07-18

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EP (1) EP3635104A1 (enExample)
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KR (1) KR102746733B1 (enExample)
CN (1) CN110997908A (enExample)
AU (1) AU2018279829B2 (enExample)
CA (1) CA3065813A1 (enExample)
MX (1) MX2019014640A (enExample)
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CN113661392B (zh) 2019-02-05 2025-05-27 卡蒂亚生物公司 有效靶向基因组操纵剂的增强选择
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CN112538471B (zh) * 2020-12-28 2023-12-12 南方医科大学 一种CRISPR SpCas9(K510A)突变体及其应用
CN117413062A (zh) * 2021-02-01 2024-01-16 爱普思伦生物公司 基因沉默
EP4286401A1 (en) * 2022-06-03 2023-12-06 Technische Universität Dresden Use of an artificial protein or of a nucleic acid encoding the artificial protein for providing a functional ribonucleoprotein complex
WO2024147677A1 (ko) * 2023-01-04 2024-07-11 고려대학교 산학협력단 2차 대사산물 증가를 위한 유전자 조작된 cas9 시스템과 이를 이용한 2차 대사산물 증진 방법
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