JP2020521440A5 - - Google Patents

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Publication number
JP2020521440A5
JP2020521440A5 JP2019559727A JP2019559727A JP2020521440A5 JP 2020521440 A5 JP2020521440 A5 JP 2020521440A5 JP 2019559727 A JP2019559727 A JP 2019559727A JP 2019559727 A JP2019559727 A JP 2019559727A JP 2020521440 A5 JP2020521440 A5 JP 2020521440A5
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JP
Japan
Prior art keywords
exon
ros1
alk
composition according
fusion gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019559727A
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English (en)
Japanese (ja)
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JP2020521440A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/EP2018/064172 external-priority patent/WO2018220004A1/en
Publication of JP2020521440A publication Critical patent/JP2020521440A/ja
Publication of JP2020521440A5 publication Critical patent/JP2020521440A5/ja
Priority to JP2023206878A priority Critical patent/JP2024019433A/ja
Pending legal-status Critical Current

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JP2019559727A 2017-05-31 2018-05-30 Alk、ret、およびros融合の多重pcr検出 Pending JP2020521440A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023206878A JP2024019433A (ja) 2017-05-31 2023-12-07 Alk、ret、およびros融合の多重pcr検出

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762513226P 2017-05-31 2017-05-31
US62/513,226 2017-05-31
PCT/EP2018/064172 WO2018220004A1 (en) 2017-05-31 2018-05-30 Multiplex pcr detection of alk, ret, and ros fusions

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023206878A Division JP2024019433A (ja) 2017-05-31 2023-12-07 Alk、ret、およびros融合の多重pcr検出

Publications (2)

Publication Number Publication Date
JP2020521440A JP2020521440A (ja) 2020-07-27
JP2020521440A5 true JP2020521440A5 (https=) 2021-07-26

Family

ID=62567625

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019559727A Pending JP2020521440A (ja) 2017-05-31 2018-05-30 Alk、ret、およびros融合の多重pcr検出
JP2023206878A Pending JP2024019433A (ja) 2017-05-31 2023-12-07 Alk、ret、およびros融合の多重pcr検出

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023206878A Pending JP2024019433A (ja) 2017-05-31 2023-12-07 Alk、ret、およびros融合の多重pcr検出

Country Status (8)

Country Link
US (2) US11505830B2 (https=)
EP (1) EP3631011B1 (https=)
JP (2) JP2020521440A (https=)
CN (1) CN110691852A (https=)
AU (1) AU2018277210B2 (https=)
CA (1) CA3059119C (https=)
ES (1) ES2883934T3 (https=)
WO (1) WO2018220004A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3059119C (en) 2017-05-31 2024-01-23 F. Hoffman-La Roche Ag Multiplex pcr detection of alk, ret, and ros fusions
CN109837275B (zh) * 2019-01-08 2022-09-06 大连医科大学附属第二医院 一种融合基因阳性对照标准品的制备方法
CN111718994A (zh) * 2019-03-22 2020-09-29 广州金域医学检验中心有限公司 肿瘤融合基因靶向检测探针、试剂盒及应用
CN110964830A (zh) * 2019-12-31 2020-04-07 中山大学达安基因股份有限公司 多重检测ros1基因突变的试剂盒及方法
CN112029857B (zh) * 2020-08-14 2026-03-24 上海真固生物科技有限公司 一种引物组合物及用于融合基因检测的试剂
CN115466788B (zh) * 2022-06-28 2026-02-10 湖南圣洲生物科技有限公司 引物探针组合、试剂盒及其检测人alk、ros1基因融合的方法
CN117144016A (zh) * 2023-10-27 2023-12-01 神州医疗科技股份有限公司 一种用于外周血循环肿瘤rna中检测ret融合基因的引物探针、试剂盒及检测系统

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5455170A (en) 1986-08-22 1995-10-03 Hoffmann-La Roche Inc. Mutated thermostable nucleic acid polymerase enzyme from Thermus species Z05
WO2000048991A1 (en) * 1999-02-18 2000-08-24 The Regents Of The University Of California Salicylamide-lanthanide complexes for use as luminescent markers
JP2004516806A (ja) * 2000-04-05 2004-06-10 モレキュラー ステージング,インコーポレイテッド プライマー伸長法を用いた対立遺伝子識別のためのプロセス
US7385043B1 (en) * 2003-04-30 2008-06-10 The Public Health Research Institute Of The City Of New York, Inc. Homogeneous multiplex screening assays and kits
EP2450437B1 (en) * 2006-04-14 2017-05-17 Cell Signaling Technology, Inc. Gene defects and mutant ALK kinase in human solid tumors
CN101466721B (zh) * 2007-04-13 2013-08-21 细胞信号技术公司 在人实体瘤中的基因缺损和突变体alk激酶
EP2470897A4 (en) * 2009-08-28 2013-05-29 Asuragen Inc MICRO-RNA BIOMARKERS OF PULMONARY DISEASE
WO2011162295A1 (ja) * 2010-06-22 2011-12-29 アステラス製薬株式会社 新規ros1融合体の検出法
US20130137111A1 (en) * 2010-07-26 2013-05-30 Astellas Pharma Inc. Detection method of novel ret fusion
US20130059762A1 (en) * 2011-04-28 2013-03-07 Life Technologies Corporation Methods and compositions for multiplex pcr
US20130237442A1 (en) * 2012-03-07 2013-09-12 University Of Miami Methods and Compositions for Diagnosis of Non-Viable Early Pregnancy
US20140272956A1 (en) 2013-03-15 2014-09-18 Abbott Molecular Inc. Method for amplification and assay of rna fusion gene variants, method of distinguishing same and related primers, probes, and kits
WO2014144121A2 (en) 2013-03-15 2014-09-18 Life Technologies Corporation Classification and actionability indices for lung cancer
US10072298B2 (en) 2013-04-17 2018-09-11 Life Technologies Corporation Gene fusions and gene variants associated with cancer
CA2943636C (en) 2014-03-25 2020-06-09 Quest Diagnostics Investments Incorporated Detection of gene fusions by intragenic differential expression (ide) using average cycle thresholds
EP3122901B1 (en) 2014-03-27 2018-08-15 Life Technologies Corporation Gene fusions and gene variants associated with cancer
IL248408B (en) * 2014-04-25 2022-06-01 Exelixis Inc A method for treating adenocarcinoma of the lungs
CN104818320B (zh) * 2014-12-03 2018-02-06 厦门艾德生物医药科技有限公司 一次性检测肺癌多重基因的引物、探针、检测体系和试剂盒
CA2982870C (en) 2015-04-17 2021-08-10 F. Hoffmann-La Roche Ag Multiplex pcr to detect gene fusions
CA3059119C (en) 2017-05-31 2024-01-23 F. Hoffman-La Roche Ag Multiplex pcr detection of alk, ret, and ros fusions

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