JP2020518552A5 - - Google Patents

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Publication number
JP2020518552A5
JP2020518552A5 JP2019542485A JP2019542485A JP2020518552A5 JP 2020518552 A5 JP2020518552 A5 JP 2020518552A5 JP 2019542485 A JP2019542485 A JP 2019542485A JP 2019542485 A JP2019542485 A JP 2019542485A JP 2020518552 A5 JP2020518552 A5 JP 2020518552A5
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JP
Japan
Prior art keywords
oligonucleotide
subunit
multimeric
multimer
stranded
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JP2019542485A
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English (en)
Japanese (ja)
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JP2020518552A (ja
JP7183167B2 (ja
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Priority claimed from PCT/US2018/017062 external-priority patent/WO2018145086A1/en
Publication of JP2020518552A publication Critical patent/JP2020518552A/ja
Publication of JP2020518552A5 publication Critical patent/JP2020518552A5/ja
Application granted granted Critical
Publication of JP7183167B2 publication Critical patent/JP7183167B2/ja
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JP2019542485A 2017-02-06 2018-02-06 減少した腎クリアランスを有する多量体オリゴヌクレオチド Active JP7183167B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762455231P 2017-02-06 2017-02-06
US62/455,231 2017-02-06
US201762522363P 2017-06-20 2017-06-20
US62/522,363 2017-06-20
US201762561853P 2017-09-22 2017-09-22
US62/561,853 2017-09-22
PCT/US2018/017062 WO2018145086A1 (en) 2017-02-06 2018-02-06 Multimeric oligonucleotides having decreased kidney clearance

Publications (3)

Publication Number Publication Date
JP2020518552A JP2020518552A (ja) 2020-06-25
JP2020518552A5 true JP2020518552A5 (https=) 2021-03-11
JP7183167B2 JP7183167B2 (ja) 2022-12-05

Family

ID=63039118

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019542485A Active JP7183167B2 (ja) 2017-02-06 2018-02-06 減少した腎クリアランスを有する多量体オリゴヌクレオチド

Country Status (11)

Country Link
US (2) US11078484B2 (https=)
EP (1) EP3576752A4 (https=)
JP (1) JP7183167B2 (https=)
KR (2) KR102623311B1 (https=)
CN (1) CN110248665A (https=)
AU (1) AU2018215684B2 (https=)
CA (1) CA3051480A1 (https=)
IL (2) IL267806B2 (https=)
MX (1) MX2019009347A (https=)
SG (1) SG11201906728TA (https=)
WO (1) WO2018145086A1 (https=)

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AU2021263932B2 (en) * 2020-04-30 2025-07-03 Mpeg La, L.L.C. Multimeric oligonucleotides with divided strands
JP2023526277A (ja) * 2020-05-13 2023-06-21 ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル 核酸リガンドコンジュゲートおよび細胞への送達のためのその使用
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