JP7183167B2 - 減少した腎クリアランスを有する多量体オリゴヌクレオチド - Google Patents

減少した腎クリアランスを有する多量体オリゴヌクレオチド Download PDF

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JP7183167B2
JP7183167B2 JP2019542485A JP2019542485A JP7183167B2 JP 7183167 B2 JP7183167 B2 JP 7183167B2 JP 2019542485 A JP2019542485 A JP 2019542485A JP 2019542485 A JP2019542485 A JP 2019542485A JP 7183167 B2 JP7183167 B2 JP 7183167B2
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oligonucleotide
multimeric
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oligonucleotides
multimeric oligonucleotide
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ジョナサン マイルズ ブラウン
ハンス‐ピーター ヴォルンロシェル
クリスティン ケイ．エイチ． ニューマン
フィリップ ハドヴィガー
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エムペグ エルエイ リミテッド ライアビリティ カンパニー
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JP2019542485A 2017-02-06 2018-02-06 減少した腎クリアランスを有する多量体オリゴヌクレオチド Active JP7183167B2 (ja)

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Application Number Priority Date Filing Date Title
US201762455231P 2017-02-06 2017-02-06
US62/455,231 2017-02-06
US201762522363P 2017-06-20 2017-06-20
US62/522,363 2017-06-20
US201762561853P 2017-09-22 2017-09-22
US62/561,853 2017-09-22
PCT/US2018/017062 WO2018145086A1 (en) 2017-02-06 2018-02-06 Multimeric oligonucleotides having decreased kidney clearance

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JP2020518552A JP2020518552A (ja) 2020-06-25
JP2020518552A5 JP2020518552A5 (https=) 2021-03-11
JP7183167B2 true JP7183167B2 (ja) 2022-12-05

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US (2) US11078484B2 (https=)
EP (1) EP3576752A4 (https=)
JP (1) JP7183167B2 (https=)
KR (2) KR102776167B1 (https=)
CN (1) CN110248665A (https=)
AU (1) AU2018215684B2 (https=)
CA (1) CA3051480A1 (https=)
IL (2) IL307726A (https=)
MX (1) MX2019009347A (https=)
SG (1) SG11201906728TA (https=)
WO (1) WO2018145086A1 (https=)

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JP2022528487A (ja) * 2019-03-29 2022-06-13 ユニバーシティ・オブ・マサチューセッツ Ｃ９ｏｒｆ７２のオリゴヌクレオチドベースの調節
US11629347B2 (en) 2019-05-06 2023-04-18 University Of Massachusetts Anti-C9ORF72 oligonucleotides and related methods
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