JP2022543191A5 - - Google Patents

Info

Publication number
JP2022543191A5
JP2022543191A5 JP2022502227A JP2022502227A JP2022543191A5 JP 2022543191 A5 JP2022543191 A5 JP 2022543191A5 JP 2022502227 A JP2022502227 A JP 2022502227A JP 2022502227 A JP2022502227 A JP 2022502227A JP 2022543191 A5 JP2022543191 A5 JP 2022543191A5
Authority
JP
Japan
Application number
JP2022502227A
Other languages
Japanese (ja)
Other versions
JP2022543191A (ja
JPWO2021021959A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/044110 external-priority patent/WO2021021959A2/en
Publication of JP2022543191A publication Critical patent/JP2022543191A/ja
Publication of JP2022543191A5 publication Critical patent/JP2022543191A5/ja
Publication of JPWO2021021959A5 publication Critical patent/JPWO2021021959A5/ja
Withdrawn legal-status Critical Current

Links

JP2022502227A 2019-07-30 2020-07-29 増強された生理活性を有する多量体オリゴヌクレオチドの皮下送達 Withdrawn JP2022543191A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962880591P 2019-07-30 2019-07-30
US62/880,591 2019-07-30
PCT/US2020/044110 WO2021021959A2 (en) 2019-07-30 2020-07-29 Subcutaneous delivery of multimeric oligonucleotides with enhanced bioactivity

Publications (3)

Publication Number Publication Date
JP2022543191A JP2022543191A (ja) 2022-10-11
JP2022543191A5 true JP2022543191A5 (https=) 2023-08-07
JPWO2021021959A5 JPWO2021021959A5 (https=) 2023-08-07

Family

ID=74228530

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022502227A Withdrawn JP2022543191A (ja) 2019-07-30 2020-07-29 増強された生理活性を有する多量体オリゴヌクレオチドの皮下送達

Country Status (8)

Country Link
US (1) US20230114023A1 (https=)
EP (1) EP4004205A4 (https=)
JP (1) JP2022543191A (https=)
CN (1) CN114466929A (https=)
AU (1) AU2020319911A1 (https=)
CA (1) CA3144467A1 (https=)
IL (1) IL289801A (https=)
WO (1) WO2021021959A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101141544B1 (ko) 2009-03-13 2012-05-03 한국과학기술원 에스아이알엔에이 다중 접합체 및 이의 제조방법
IL316159A (en) 2015-06-15 2024-12-01 Mpeg La Llc Defined Oligonucleotide Multimers and Methods for Manufacture Thereof
EP3576752A4 (en) 2017-02-06 2020-12-16 Mpeg La, LLC MULTIMERIC OLIGONUCLEOTIDES WITH REDUCED RENAL CLEARANCE
US20230372508A1 (en) * 2022-05-19 2023-11-23 Olix Us, Inc. Linkers coupling functional ligands to macromolecules
WO2025100427A1 (ja) * 2023-11-06 2025-05-15 国立研究開発法人国立循環器病研究センター 肺高血圧症の予防および/または治療用医薬

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060035815A1 (en) * 2004-05-04 2006-02-16 Nastech Pharmaceutical Company Inc. Pharmaceutical compositions for delivery of ribonucleic acid to a cell
DK2539451T3 (da) * 2010-02-24 2016-04-04 Arrowhead Res Corp Sammensætninger til målrettet tilførsel af siRNA
EP2895200B1 (en) * 2012-09-14 2019-11-06 Translate Bio MA, Inc. Multimeric oligonucleotide compounds
US10077443B2 (en) * 2012-11-15 2018-09-18 Roche Innovation Center Copenhagen A/S Oligonucleotide conjugates
CN104955952A (zh) * 2013-01-30 2015-09-30 弗·哈夫曼-拉罗切有限公司 Lna寡核苷酸碳水化合物缀合物
IL316159A (en) * 2015-06-15 2024-12-01 Mpeg La Llc Defined Oligonucleotide Multimers and Methods for Manufacture Thereof
EP3576752A4 (en) * 2017-02-06 2020-12-16 Mpeg La, LLC MULTIMERIC OLIGONUCLEOTIDES WITH REDUCED RENAL CLEARANCE

Similar Documents

Publication Publication Date Title
BR112023005462A2 (https=)
BR112023012656A2 (https=)
BR112021014123A2 (https=)
BR112023009656A2 (https=)
BR112022009896A2 (https=)
BR112021017747A2 (https=)
BR112022024743A2 (https=)
BR112022026905A2 (https=)
BR112023011738A2 (https=)
BR112023004146A2 (https=)
BR112023006729A2 (https=)
BR102021018859A2 (https=)
BR102021015500A2 (https=)
BR102021007058A2 (https=)
BR102020022030A2 (https=)
BR112023016292A2 (https=)
BR112023011539A2 (https=)
BR112023011610A2 (https=)
BR112023008976A2 (https=)
BR102021020147A2 (https=)
BR102021018926A2 (https=)
BR102021018167A2 (https=)
BR102021017576A2 (https=)
BR102021016837A2 (https=)
BR102021016551A2 (https=)