JP2020511462A - キナーゼ阻害剤との組み合わせで治療用ｔ細胞を使用するための方法および組成物 - Google Patents

キナーゼ阻害剤との組み合わせで治療用ｔ細胞を使用するための方法および組成物 Download PDF

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JP2020511462A
JP2020511462A JP2019550557A JP2019550557A JP2020511462A JP 2020511462 A JP2020511462 A JP 2020511462A JP 2019550557 A JP2019550557 A JP 2019550557A JP 2019550557 A JP2019550557 A JP 2019550557A JP 2020511462 A JP2020511462 A JP 2020511462A
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マイケル ポーツ
マイケル ポーツ
ジム チン
ジム チン
ルース サーモン
ルース サーモン
オレクサンドル バトゥレビッチ
オレクサンドル バトゥレビッチ
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ジュノー セラピューティクス インコーポレイテッド
ジュノー セラピューティクス インコーポレイテッド
アサータ ファーマ リミテッド ライアビリティ カンパニー
アサータ ファーマ リミテッド ライアビリティ カンパニー
アサータ ファーマ ベー．フェー．
アサータ ファーマ ベー．フェー．
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/00—Medicinal preparations characterised by special physical form
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K40/31—Chimeric antigen receptors [CAR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/033—Fusion polypeptide containing a localisation/targetting motif containing a motif for targeting to the internal surface of the plasma membrane, e.g. containing a myristoylation motif

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JP2019550557A 2016-12-03 2017-12-01 キナーゼ阻害剤との組み合わせで治療用ｔ細胞を使用するための方法および組成物 Withdrawn JP2020511462A (ja)

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JP2022207877A JP2023036841A (ja) 2016-12-03 2022-12-26 キナーゼ阻害剤との組み合わせで治療用ｔ細胞を使用するための方法および組成物

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US201662429732P 2016-12-03 2016-12-03
US62/429,732 2016-12-03
US201762581644P 2017-11-03 2017-11-03
US62/581,644 2017-11-03
PCT/US2017/064362 WO2018102785A2 (en) 2016-12-03 2017-12-01 Methods and compositions for use of therapeutic t cells in combination with kinase inhibitors

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JP2022207877A Pending JP2023036841A (ja) 2016-12-03 2022-12-26 キナーゼ阻害剤との組み合わせで治療用ｔ細胞を使用するための方法および組成物

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US (2) US11590167B2 (https=)
EP (1) EP3548046A2 (https=)
JP (2) JP2020511462A (https=)
CN (1) CN110545826A (https=)
AU (1) AU2017368331A1 (https=)
CA (1) CA3045339A1 (https=)
MA (1) MA46995A (https=)
MX (2) MX2019006288A (https=)
WO (1) WO2018102785A2 (https=)

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