JP2020509992A - 難溶性化合物を含むパーソナルケア組成物 - Google Patents
難溶性化合物を含むパーソナルケア組成物 Download PDFInfo
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- A61K8/04—Dispersions; Emulsions
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- A61K8/064—Water-in-oil emulsions, e.g. Water-in-silicone emulsions
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- A61K8/04—Dispersions; Emulsions
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
- A61K8/894—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a polyoxyalkylene group, e.g. cetyl dimethicone copolyol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/02—Preparations containing skin colorants, e.g. pigments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/21—Emulsions characterized by droplet sizes below 1 micron
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Abstract
Description
局所的油中水型パーソナルケアエマルション組成物を作製する方法であって、
a.約0.5〜約10%のシスチンを9〜14のpHの塩基性水溶液に混合して、シスチンの水溶液を得るステップと、
b.前記シスチンの水溶液を化粧品的に許容される油および1〜12のHLBを有する1〜15%の乳化剤と混合して、油中水型プレエマルションを得るステップと、
c.前記プレエマルションを1〜4.5のpHの酸性水溶液と混合するステップと、
d.前記プレエマルションのpHを3.5〜8.5のpH範囲に減少させ、かつ前記プレエマルション中の水相の液滴サイズを、90%〜100%の液滴が100nm〜20ミクロンの範囲の直径を有するように減少させるステップと
を含む、局所的油中水型パーソナルケアエマルション組成物を作製する方法であって、
前記エマルションが10〜70%の水相を含み、前記塩基性水溶液対前記酸性水溶液の重量比が4:1〜1:1の範囲にある、局所的油中水型パーソナルケアエマルション組成物を作製する方法
を含む。
ステップa:9〜14、または9〜12、または9〜10、または9.4のpHの塩基性水溶液に0.5〜10%、または0.5〜1.3%のシスチンを混合して、シスチンの水溶液を得る。塩基性水溶液は、アルカリおよびアルカリ金属水酸化物、モノエタノールアミン、ジエタノールアミン、トリエタノールアミン、およびその混合物を含むがこれらに限定されない適した強塩基を用いて調製される。シスチンの量が多いほど、必要とされる塩基性溶液のpHは、高くなる。溶液を、目に見える結晶が見られなくなるまで、穏やかに攪拌しながら室温で調製する。
本発明の油中水型組成物は、そのまま使用され得る。代わりに、本発明の油中水型エマルションは、油中水型または水中油型または多重エマルションである最終製品の構成成分とすることができる。本発明の組成物は、好ましくはリーブオン組成物である。本発明の組成物は、好ましくは、皮膚上に残るように適用されるリーブオン組成物である。これらのリーブオン組成物は、皮膚に適用され、その後製品の適用後または適用中に洗浄、すすぎ、拭き取りなどのいずれかによって除去される組成物とは区別されるべきである。リンスオフ組成物に典型的に使用される界面活性剤は、リンスオフ組成物に使用中にすすぎが容易な気泡/泡を生成する能力を与える物理化学的特性を有し、それらは、アニオン性、カチオン性、両性、および非イオン性の混合物からなり得る。一方、リーブオン組成物に使用される界面活性剤は、そのような特性を有する必要はない。むしろ、リーブオン組成物は、洗い流されることが意図されていないので、それらは、非刺激性である必要があり、したがって、リーブオン組成物中の界面活性剤の総レベルおよびアニオン性界面活性剤の総レベルを最小にする必要がある。本発明の組成物中の界面活性剤の総レベルは、好ましくは1%〜15%以下、より好ましくは10%未満、最も好ましくは最大9%、最適には最大6%である。
いくつかの実施形態では、スキンケア組成物は、ヒト皮膚に局所的に適用される。いくつかの実施形態では、スキンケア組成物は、皮膚調節、皮膚を滑らかにすること、しわや老化した肌の軽減、肌の炎症の軽減、乾燥の軽減、年齢によるしみの軽減、日焼けの軽減、および皮膚の美白化からなる群から選択される少なくとも1つの利益を提供する。
エマルションを以下のように調製した。
L−シスチン結晶化挙動を、以下のように、低温SEMを用いて研究した。
化学的安定性
シスチン化学的安定性を、45℃で30日間の保管後に室温で評価した。試料1、2、および3を本発明の方法によって調製した。試料4は、ここで試料を、シスチンをその後の酸性溶液での中和なしに単に高pHで溶解することによってのみ調製したことを除いて、試料2の複製であった。
Claims (10)
- 局所的油中水型パーソナルケアエマルション組成物を作製する方法であって、
a.約0.5〜約10%のシスチンを9〜14のpHの塩基性水溶液に混合して、シスチンの水溶液を得るステップと、
b.前記シスチンの水溶液を化粧品的に許容される油および1〜12のHLBを有する1〜15%の乳化剤と混合して、油中水型プレエマルションを得るステップと、
c.前記プレエマルションを1〜4.5のpHの酸性水溶液と混合するステップと、
d.前記プレエマルションのpHを3.5〜8.5のpH範囲に減少させ、かつ前記プレエマルション中の水相の液滴サイズを、90%〜100%の液滴が100nm〜20ミクロンの範囲の直径を有するように減少させるステップと
を含み、
ここで、前記エマルションが10〜70%の水相を含み、前記塩基性水溶液対前記酸性水溶液の重量比が4:1〜1:1の範囲にある、方法。 - 前記酸性水溶液が鉱酸、脂肪酸、ヒドロキシカルボン酸、ジカルボン酸、ポリカルボン酸、およびその混合物から選択される酸を含む、請求項1に記載の方法。
- ステップcおよびdが同時に行われる、請求項1または2に記載の方法。
- 前記エマルションの粘度が1Pas〜500Pasの範囲にある、請求項1〜3のいずれかに記載の方法。
- ステップdが前記プレエマルションを高剪断に供することを含む、請求項1〜4のいずれか一項に記載の方法。
- 局所的パーソナルケア油中水型エマルション組成物であって、前記エマルションの重量で、
a.約0.001%〜約2%のシスチンを含む約10%〜約70%の水相と、
b.約1〜約15%の乳化剤と
を含み、
ここで、水相対油相の重量比が4:1〜1:1であり、
前記エマルションのpHが3.5〜8.5の範囲にあり、
水相中の水滴の90%〜100%が100nm〜20ミクロンのサイズ範囲内の直径を有し、
シスチンが水滴中に可溶化または非結晶化状態で存在する、組成物。 - 前記組成物がリーブオン非固形皮膚化粧品組成物である、請求項1〜6のいずれか一項に記載の組成物。
- 前記組成物がバニシングクリームである、請求項1〜7のいずれか一項に記載の組成物。
- 前記乳化剤が、エトキシル化非イオン性界面活性剤、ポリグリセロールエステル、スクロースポリ脂肪酸エステル、シリコーン乳化剤、PEG10ジメチコン、およびラウリルPEG−10トリス(トリメチルシロキシ)シリルエチルジメチコンからなる群から選択される、請求項1〜8のいずれか一項に記載の組成物。
- 前記組成物が、グルタミン、グリシン、およびその混合物からなる群から選択されるアミノ酸をさらに含む、請求項1〜9のいずれか一項に記載の組成物。
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US201662437235P | 2016-12-21 | 2016-12-21 | |
US62/437,235 | 2016-12-21 | ||
PCT/EP2017/083207 WO2018114745A1 (en) | 2016-12-21 | 2017-12-18 | Personal care compositions comprising poorly soluble compounds |
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US (2) | US10751267B2 (ja) |
EP (1) | EP3558243B1 (ja) |
JP (1) | JP7084924B2 (ja) |
CN (1) | CN110121331B (ja) |
CA (1) | CA3046721A1 (ja) |
EA (1) | EA201991003A1 (ja) |
PH (1) | PH12019501106A1 (ja) |
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CN110121330B (zh) | 2016-12-21 | 2022-04-29 | 联合利华知识产权控股有限公司 | 具有包含4-取代的间苯二酚和氨基酸的谷胱甘肽前体的个人护理组合物 |
US11337908B2 (en) | 2016-12-21 | 2022-05-24 | Conopco, Inc. | Personal care compositions with cystine |
CN110785161B (zh) | 2017-06-23 | 2023-06-20 | 宝洁公司 | 用于改善皮肤外观的组合物和方法 |
CN112437657A (zh) | 2018-07-03 | 2021-03-02 | 宝洁公司 | 处理皮肤状况的方法 |
WO2020200979A1 (en) * | 2019-04-01 | 2020-10-08 | Unilever Plc | Multiple emulsion comprising an oil continuous nanoemulsion and a method for using the same |
FR3109526B1 (fr) * | 2020-04-22 | 2022-05-13 | Elegant Best Investment Ltd | Démaquillant moussant |
EP4142680B1 (en) * | 2020-04-28 | 2023-10-18 | Unilever IP Holdings B.V. | Stabilized cosmetic compositions with n, n'-di-acetyl cystine |
EP4142677A1 (en) | 2020-04-28 | 2023-03-08 | Unilever IP Holdings B.V. | Personal care compositions with enhanced solubility actives |
US10959933B1 (en) | 2020-06-01 | 2021-03-30 | The Procter & Gamble Company | Low pH skin care composition and methods of using the same |
CN115843238A (zh) | 2020-06-01 | 2023-03-24 | 宝洁公司 | 改善维生素b3化合物渗透到皮肤中的方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2014505712A (ja) * | 2011-02-17 | 2014-03-06 | ユニリーバー・ナームローゼ・ベンノートシヤープ | 連続油相を有し12−ヒドロキシステアリン酸を含有しているリーブオン非固体皮膚コンディショニング組成物 |
JP2014080384A (ja) * | 2012-10-16 | 2014-05-08 | Hoyu Co Ltd | 毛髪処理剤組成物 |
JP2015205859A (ja) * | 2014-04-23 | 2015-11-19 | 富士フイルム株式会社 | 分散組成物及び化粧料 |
JP2016033116A (ja) * | 2014-07-31 | 2016-03-10 | 富士フイルム株式会社 | 皮膚外用剤 |
Family Cites Families (110)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB720561A (en) | 1952-04-17 | 1954-12-22 | Frederick Victor Wells | Improvements in preparations for application to the hair and scalp |
GB874368A (en) | 1957-12-09 | 1961-08-02 | Irwin Irville Lubowe | Improvements in anti-seborrheic and scalp preparations |
NL120093C (ja) | 1958-07-24 | |||
GB987800A (en) | 1962-02-13 | 1965-03-31 | Shiseido Co Ltd | Improvements in or relating to toilet preparations containing amino acids |
GB1050756A (ja) | 1964-09-10 | 1900-01-01 | ||
US3786076A (en) | 1966-10-13 | 1974-01-15 | J Morelle | Lipoaminoacids |
JPS5032533B1 (ja) | 1969-02-27 | 1975-10-22 | ||
BE793930A (fr) | 1972-01-12 | 1973-05-02 | Athlon Corp | Composition pour le conditionnement de la peau |
US4201235A (en) | 1978-01-03 | 1980-05-06 | Mare Corporation | Amino acid-vitamin formulations for skin, hair and scalp conditioners |
JPS61227515A (ja) | 1985-04-01 | 1986-10-09 | Shiseido Co Ltd | 皮膚外用剤 |
US4707354A (en) | 1985-06-17 | 1987-11-17 | Alpen Tau, Inc. | Mature skin treatment and protectant compositions and methods of using same |
US4677120A (en) | 1985-07-31 | 1987-06-30 | Molecular Design International | Topical prodrugs for treatment of acne and skin diseases |
USRE37934E1 (en) | 1986-08-28 | 2002-12-10 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system |
AT402931B (de) * | 1986-11-07 | 1997-09-25 | Pharmacia Gmbh | Verfahren zur herstellung von neuen cystinverbindungen und derenverwendung |
FR2608424B1 (fr) | 1986-12-17 | 1989-06-16 | Cazacou Cecilia | Accelerateur de bronzage sans ecran solaire utilisant un complexe naturel favorisant la melanogenese |
US4885157A (en) | 1987-02-13 | 1989-12-05 | Fiaschetti Mary G | Dermal cosmetic composition and applications therefor |
US5124356A (en) | 1987-06-29 | 1992-06-23 | Molecular Design International, Inc. | Dermal uses of trans-retinoids for the treatment of photoaging |
USRE34075E (en) | 1987-06-29 | 1992-09-22 | Molecular Design International, Inc. | Dermal uses of trans-retinoids for the treatment of cancer |
US4885311A (en) | 1987-06-29 | 1989-12-05 | Molecular Design International | Topical transretinoids for treatment of acne and skin diseases |
GB2212722B (en) | 1987-11-25 | 1991-12-11 | Theravit Limited | Vitamin compositions |
US5049584A (en) | 1988-12-14 | 1991-09-17 | Molecular Design International | Dermal uses of cis-retinoids for the treatment of cancer |
US5133958A (en) | 1989-04-20 | 1992-07-28 | Erwin Stuckler | Agent for nail, skin and hair care |
FR2660196A1 (fr) | 1990-03-28 | 1991-10-04 | Courmontagne Albert | Procede de fabrication d'extrait cellulaire hydrosoluble d'embryons d'óoeuf et produit obtenu. |
JP3091270B2 (ja) | 1990-09-28 | 2000-09-25 | 協和醗酵工業株式会社 | 美白化粧料 |
US5198465A (en) | 1991-06-19 | 1993-03-30 | Dioguardi Francesco S | Compositions based on amino acids for preventing and treating precursor deficiencies in the synthesis of collagen |
US5254331A (en) | 1991-09-12 | 1993-10-19 | Chanel, Inc. | Skin cream composition |
TW233264B (ja) | 1992-02-03 | 1994-11-01 | Otsuka Pharma Co Ltd | |
IL101007A (en) | 1992-02-18 | 1997-08-14 | Pharmos Ltd | Dry stable compositions prepared by lyophilization |
JP3170070B2 (ja) * | 1992-10-16 | 2001-05-28 | 株式会社コーセー | 皮膚外用剤 |
DE4328871A1 (de) | 1993-08-27 | 1995-03-02 | Beiersdorf Ag | Mittel gegen empfindliche, hyperreaktive Hautzustände, atopische Dermatiden, Pruritus, Psoriasis Prurigo, Photodermatosen und Ichthyosis |
US5416075A (en) | 1993-11-30 | 1995-05-16 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Biospecific emulsions |
FR2718637A1 (fr) | 1994-04-15 | 1995-10-20 | Oreal | Composition cosmétique à appliquer sur l'ongle. |
DE19509354A1 (de) | 1994-12-08 | 1996-06-13 | Klett Loch Lore M | Kombinationspräparat zur Förderung des Haarwachstums und ggf. des Haut- und Nagelwachstums sowie zur Verhinderung bzw. zur Beseitigung von Haarausfall |
DE19510732C1 (de) | 1995-03-24 | 1996-05-23 | Tscheulin Rothal Gmbh | Verfahren zum Verschließen einer Behälteröffnung, Behälter mit einem Behälterverschluß sowie Deckelmaterial zur Herstellung eines solchen Behälterverschlusses |
GB9506926D0 (en) * | 1995-04-04 | 1995-05-24 | Croda Int Plc | Cystine-siicone copolymers and their use for treating keratin substrates |
US5715555A (en) | 1995-09-12 | 1998-02-10 | Motorola Inc. | Smart laundry system and methods therefor |
US5958976A (en) | 1997-09-19 | 1999-09-28 | E-L Management Corp. | Composition and method for reducing stinging in skin |
DE19831798A1 (de) | 1998-07-15 | 2000-01-27 | Mandorlo Investment Gmbh Luxem | Mittel zur Pflege und/oder Behandlung von Haut und Gewebe |
CN100453531C (zh) | 1998-10-09 | 2009-01-21 | 味之素株式会社 | 半胱氨酸衍生物 |
US6149925A (en) | 1998-11-05 | 2000-11-21 | Color Access, Inc. | Topical compositions for enhancing glutathione production |
EP1189584A4 (en) | 1999-05-18 | 2006-01-25 | Cosmeceuticals Inc Excel | CARE AND DERMATOLOGICAL COMPOSITION BASED ON ALPHA-AMINO ACID |
FR2795309B1 (fr) | 1999-06-28 | 2004-10-01 | Nippon Fine Chemical Co | Substances huileuses comprenant un ester de dimerdiol et produits cosmetiques comprenant cet ester |
EP1289537B1 (en) | 2000-05-31 | 2005-11-30 | Encelle, Inc. | Method of treating chronic ulcers |
DE10130963A1 (de) | 2001-06-27 | 2003-01-16 | Beiersdorf Ag | Verwendung von Bis-Resorcinyltriazinderivaten zur Verbesserung der Wirksamkeit von lipophilen Wirkstoffen in kosmetischen oder dermatologischen Zubereitungen |
KR100941662B1 (ko) | 2001-10-09 | 2010-02-11 | 가부시키가이샤환케루 | 글루타티온 증강용 조성물 |
US6858217B2 (en) | 2002-03-22 | 2005-02-22 | Unilever Home & Personal Care Usa Division Of Conopco, Inc. | Stabilization of terpenoids in cosmetic compositions |
US6869598B2 (en) | 2002-03-22 | 2005-03-22 | Unilever Home & Personal Care Usa Division Of Conopco, Inc. | Stabilization of sunscreens in cosmetic compositions |
US6863897B2 (en) | 2002-03-22 | 2005-03-08 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Stabilization of resorcinol derivatives in cosmetic compositions |
US20030232091A1 (en) | 2002-06-17 | 2003-12-18 | Adi Shefer | Stabilized retinol for cosmetic dermatological, and pharmaceutical compositions, and use thereof |
US6592908B1 (en) | 2002-09-23 | 2003-07-15 | Albert Crum | Nutritional or therapeutic compositions |
EP1459736A1 (en) | 2003-03-14 | 2004-09-22 | The Procter & Gamble Company | Skin care composition that increase and repair skin barrier function |
US20050031571A1 (en) | 2003-05-16 | 2005-02-10 | Khaiat Alain V. | Topical treatment of ingrown hairs |
US20050192229A1 (en) | 2004-02-27 | 2005-09-01 | Perricone Nicholas V. | Topical glutathione treatments |
WO2005097060A1 (fr) | 2004-03-12 | 2005-10-20 | Societe D'extraction Des Principes Actifs Sa (Vincience) | Utilisation de peptides en tant qu’agent antioxydant pour la preparation d’ une composition cosmetique et/ou pharmaceutique |
US20050271726A1 (en) | 2004-06-02 | 2005-12-08 | Albert Crum | Immune enhancing compositions and methods of use thereof |
JP2006001903A (ja) | 2004-06-21 | 2006-01-05 | Kanebo Ltd | 美白剤、及びそれを含有する組成物 |
US7282471B2 (en) | 2005-09-08 | 2007-10-16 | Conopco, Inc. | Personal care compositions with glycerin and hydroxypropyl quaternary ammonium salts |
US7300649B2 (en) | 2005-02-11 | 2007-11-27 | Genepharm, Inc. | Cosmetic and cosmeceutical compositions for restoration of skin barrier function |
DE602006011154D1 (de) | 2005-04-28 | 2010-01-28 | Basf Se | Verwendung von benzotriazolderivaten zur photostabilisierung |
KR101165848B1 (ko) | 2005-08-18 | 2012-07-13 | (주)아모레퍼시픽 | 효소 및 아미노산을 함유하는 피부 화장료 조성물 |
WO2007042472A1 (en) | 2005-10-14 | 2007-04-19 | Symrise Gmbh & Co. Kg | Synergistic mixtures of bisabolol and ginger extract |
US8147815B2 (en) | 2005-12-16 | 2012-04-03 | Celmatrix Corporation | Topical administration carrier composition and therapeutic formulations comprising same |
CN101400772B (zh) | 2006-03-08 | 2013-06-26 | 路博润高级材料公司 | 稳定的皂基清洁体系 |
CA2671133C (en) | 2006-12-01 | 2015-11-24 | Anterios, Inc. | Peptide nanoparticles and uses therefor |
WO2008082524A1 (en) | 2006-12-19 | 2008-07-10 | National Stem Cell Inc. | Embryonic germ cell secreted product derived topical compositions and methods of use thereof |
US8440172B2 (en) | 2007-07-09 | 2013-05-14 | Symrise Ag | Stable soluble salts of phenylbenzimidazole sulfonic acid at PHS at or below 7.0 |
US20110183040A1 (en) | 2007-08-03 | 2011-07-28 | Ermolin Gennady A | Amino Acid and Peptide Products |
EP2192890A1 (en) | 2007-09-14 | 2010-06-09 | L'Oreal | Compositions and methods for treating keratinous substrates |
JP2009242321A (ja) | 2008-03-31 | 2009-10-22 | Shiseido Co Ltd | 皮膚外用剤 |
US20090263513A1 (en) | 2008-04-18 | 2009-10-22 | Jan Marini | Cosmetic skin lightening formulation |
US20090317341A1 (en) | 2008-06-18 | 2009-12-24 | Conopco, Inc., D/B/A Unilever | Compositions for Lightening Skin Color |
ES2336995B1 (es) | 2008-10-13 | 2011-02-09 | Lipotec, S.A. | Composicion cosmetica o dermofarmaceutica para el cuidado de la piel,cuero cabelludo y uñas. |
EA200900146A1 (ru) | 2008-12-26 | 2010-02-26 | Некоммерческое Учреждение "Научно-Исследовательский Институт Цитохимии И Молекулярной Фармакологии" | Композиция аминокислот подъязычного применения для повышения репигментации кожного покрова при витилиго и способ ее применения |
CN101773458A (zh) | 2009-01-12 | 2010-07-14 | 孙海 | 一种肤感清爽的啫喱美白防护乳粉 |
US8299127B2 (en) | 2009-03-11 | 2012-10-30 | Conopco, Inc. | Method and composition for evenly applying water soluble actives |
US20100305169A1 (en) | 2009-03-23 | 2010-12-02 | Larry Rich Robinson | Personal-care composition comprising a cationic active |
ES2638046T3 (es) | 2009-03-30 | 2017-10-18 | Shiseido Company, Ltd. | Composiciones para aliviar los daños inducidos por la radiación ultravioleta |
JP5032533B2 (ja) | 2009-06-09 | 2012-09-26 | 富士通テレコムネットワークス株式会社 | フレーム伝送装置及びフレーム廃棄数測定方法 |
JP2013509988A (ja) | 2009-11-06 | 2013-03-21 | ザ プロクター アンド ギャンブル カンパニー | 有益剤を含む高効率のカプセル |
WO2011062640A1 (en) | 2009-11-23 | 2011-05-26 | New York University | Compounds as l-cystine crystallization inhibitors and uses thereof |
US8722026B2 (en) | 2010-01-06 | 2014-05-13 | Elc Management, Llc | Skin lightening compositions |
CN102150866B (zh) | 2010-02-12 | 2014-10-15 | 悠哈味觉糖有限公司 | 含胱氨酸复合体及其制造方法 |
CN101797213A (zh) | 2010-04-26 | 2010-08-11 | 任芳芳 | 氨基酸抗衰老霜 |
JP2011256137A (ja) | 2010-06-09 | 2011-12-22 | Shiseido Co Ltd | アミノ酸含有組成物における防腐力低下抑制剤 |
KR101275351B1 (ko) | 2010-06-29 | 2013-06-17 | (주)아모레퍼시픽 | 노화방지용 화장료 조성물 |
US8895628B2 (en) | 2010-10-25 | 2014-11-25 | Johnson & Johnson Consumer Companies, Inc. | Compositions comprising a retinoid and an NFkB-inhibitor and their methods of use |
SG191879A1 (en) | 2011-01-07 | 2013-08-30 | Allergan Inc | Melanin modification compositions and methods of use |
ES2717178T3 (es) | 2011-03-21 | 2019-06-19 | Broda Tech Co Ltd | Composiciones de hidrogel inversamente termorreversible |
US8795643B1 (en) | 2011-04-29 | 2014-08-05 | Michael Mark Anthony | Method of preparing a hair treatment formulation comprising nanoparticles in solution and method of hair treatment utilizing a treatment formulation comprising nanoparticles in solution |
US8916609B2 (en) | 2011-06-10 | 2014-12-23 | New York University | Compounds as L-cystine crystallization inhibitors and uses thereof |
WO2013009250A1 (en) | 2011-07-11 | 2013-01-17 | Delaval Holding Ab | A device to motivate an animal to leave a milking stall |
DE102011110909A1 (de) * | 2011-08-18 | 2013-02-21 | Paul Hartmann Ag | Zusammensetzungen mit einer die Hautbarriere verbessernden Wirkstoffkombination |
US8828235B2 (en) | 2011-08-22 | 2014-09-09 | Monmouth University | Method for removing contaminants from water using thiol-modified surfaces containing ester linkages |
US10639252B2 (en) | 2011-09-23 | 2020-05-05 | Allergan, Inc. | Compositions for skin exfoliation and use thereof |
CN102366397B (zh) | 2011-11-29 | 2013-01-30 | 宝健(中国)日用品有限公司 | 一种美白淡斑亮肤组合物、含有该组合物的护肤品及制备方法 |
CA2854700A1 (en) | 2011-12-20 | 2013-06-27 | Unilever Plc | Moisturizing composition comprising an aminopeptide mixture |
JP6115086B2 (ja) | 2012-11-13 | 2017-04-19 | 味の素株式会社 | アミノ酸化合物の酢酸塩を含有する化粧料組成物 |
US8778910B2 (en) | 2012-12-07 | 2014-07-15 | Conopco, Inc. | Concentrated lamellar liquid personal cleansing composition |
CA2896646A1 (en) | 2012-12-27 | 2014-07-03 | Hayashibara Co., Ltd. | Skin-exterior anti-ageing composition and production method therefor |
US9428453B2 (en) | 2013-01-02 | 2016-08-30 | Rutgers, The State University Of New Jersey | Cystine diamide analogs for the prevention of cystine stone formation in cystinuria |
JP6039484B2 (ja) | 2013-03-29 | 2016-12-07 | 富士フイルム株式会社 | 組成物及び化粧料 |
KR101551728B1 (ko) | 2013-07-09 | 2015-09-09 | 휴먼바이오텍 주식회사 | 성장인자 및 아미노산을 포함하는 것을 특징으로 하는 기능성 화장료 조성물 |
JP6212320B2 (ja) | 2013-08-01 | 2017-10-11 | ポーラ化成工業株式会社 | 皮膚外用剤 |
ES2925879T3 (es) | 2013-10-30 | 2022-10-20 | Chromadex Inc | Composiciones de ribósido de nicotinamida para uso tópico en el tratamiento de afecciones de la piel |
AU2015306676A1 (en) | 2014-08-29 | 2017-03-09 | Albert B. Crum | A method for side effect reduction in the use of statins via physiologically synthesized glutathione |
KR20160123753A (ko) | 2015-04-17 | 2016-10-26 | (주)제이준코스메틱 | 피부미백용 조성물 |
US9872832B2 (en) | 2015-10-23 | 2018-01-23 | LG Bionano, LLC | Nanoemulsions having reversible continuous and dispersed phases |
CN105919827A (zh) | 2016-06-01 | 2016-09-07 | 北京希诺赛尔健康科技推广有限公司 | 一种具有保湿抗皱作用的护肤组合物 |
JP7084567B2 (ja) | 2016-12-21 | 2022-06-15 | ユニリーバー・アイピー・ホールディングス・ベスローテン・ヴェンノーツハップ | ニコチンアミドとアミノ酸とを含むグルタチオン前駆体を含むパーソナルケア組成物 |
CN107411982A (zh) | 2017-05-09 | 2017-12-01 | 刘毅 | 美白保湿修复护肤组合物及其制备方法和应用 |
-
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-
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- 2020-07-13 US US16/927,852 patent/US10980718B2/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2014505712A (ja) * | 2011-02-17 | 2014-03-06 | ユニリーバー・ナームローゼ・ベンノートシヤープ | 連続油相を有し12−ヒドロキシステアリン酸を含有しているリーブオン非固体皮膚コンディショニング組成物 |
JP2014080384A (ja) * | 2012-10-16 | 2014-05-08 | Hoyu Co Ltd | 毛髪処理剤組成物 |
JP2015205859A (ja) * | 2014-04-23 | 2015-11-19 | 富士フイルム株式会社 | 分散組成物及び化粧料 |
JP2016033116A (ja) * | 2014-07-31 | 2016-03-10 | 富士フイルム株式会社 | 皮膚外用剤 |
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