JP2020508985A5 - - Google Patents

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Publication number
JP2020508985A5
JP2020508985A5 JP2019543376A JP2019543376A JP2020508985A5 JP 2020508985 A5 JP2020508985 A5 JP 2020508985A5 JP 2019543376 A JP2019543376 A JP 2019543376A JP 2019543376 A JP2019543376 A JP 2019543376A JP 2020508985 A5 JP2020508985 A5 JP 2020508985A5
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JP
Japan
Prior art keywords
pharmaceutically acceptable
acceptable salt
dendrimer
formula
peg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2019543376A
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English (en)
Japanese (ja)
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JP2020508985A (ja
JP7074761B2 (ja
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Publication date
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Priority claimed from PCT/EP2018/054420 external-priority patent/WO2018154004A1/en
Publication of JP2020508985A publication Critical patent/JP2020508985A/ja
Publication of JP2020508985A5 publication Critical patent/JP2020508985A5/ja
Application granted granted Critical
Publication of JP7074761B2 publication Critical patent/JP7074761B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2019543376A 2017-02-22 2018-02-22 治療用デンドリマー Expired - Fee Related JP7074761B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762461983P 2017-02-22 2017-02-22
US62/461,983 2017-02-22
US201762488151P 2017-04-21 2017-04-21
US62/488,151 2017-04-21
US201762591823P 2017-11-29 2017-11-29
US62/591,823 2017-11-29
PCT/EP2018/054420 WO2018154004A1 (en) 2017-02-22 2018-02-22 Therapeutic dendrimers

Publications (3)

Publication Number Publication Date
JP2020508985A JP2020508985A (ja) 2020-03-26
JP2020508985A5 true JP2020508985A5 (enExample) 2021-03-11
JP7074761B2 JP7074761B2 (ja) 2022-05-24

Family

ID=61386833

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019543376A Expired - Fee Related JP7074761B2 (ja) 2017-02-22 2018-02-22 治療用デンドリマー

Country Status (23)

Country Link
US (4) US10314920B2 (enExample)
EP (1) EP3585441A1 (enExample)
JP (1) JP7074761B2 (enExample)
KR (2) KR102544033B1 (enExample)
CN (2) CN110312531A (enExample)
AU (1) AU2018223149B2 (enExample)
BR (1) BR112019016409A2 (enExample)
CA (1) CA3053069A1 (enExample)
CL (1) CL2019002240A1 (enExample)
CO (1) CO2019009722A2 (enExample)
CR (1) CR20190361A (enExample)
DO (1) DOP2019000204A (enExample)
EC (1) ECSP19056271A (enExample)
IL (1) IL268648B (enExample)
JO (1) JOP20190191B1 (enExample)
MX (1) MX2019009442A (enExample)
NI (1) NI201900088A (enExample)
PE (1) PE20191660A1 (enExample)
PH (1) PH12019501896A1 (enExample)
SG (1) SG11201907334QA (enExample)
TW (1) TWI773730B (enExample)
UA (1) UA125655C2 (enExample)
WO (1) WO2018154004A1 (enExample)

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Publication number Priority date Publication date Assignee Title
US20180326081A1 (en) * 2011-06-06 2018-11-15 Starpharma Pty Ltd Macromolecules
TWI773730B (zh) * 2017-02-22 2022-08-11 瑞典商阿斯特捷利康公司 治療性樹枝狀聚合物
TWI856967B (zh) 2018-08-17 2024-10-01 瑞典商阿斯特捷利康公司 樹枝狀體配製物
TWI831817B (zh) * 2018-08-17 2024-02-11 瑞典商阿斯特捷利康公司 治療癌症之方法
JP7550149B2 (ja) * 2018-11-20 2024-09-12 スターファーマ ピーティーワイ エルティーディー 治療用デンドリマー
CN113825397B (zh) 2019-05-07 2023-10-27 赛丹思科大学 用于布撒生物材料的机件
WO2021056077A1 (en) * 2019-09-26 2021-04-01 Starpharma Pty Ltd Therapeutic dendrimer
AU2020397063A1 (en) * 2019-12-04 2022-07-07 Ashvattha Therapeutics, Inc. Dendrimer compositions and methods for drug delivery
WO2021213492A1 (zh) * 2020-04-24 2021-10-28 上海森辉医药有限公司 一类载药的大分子及其制备方法
PH12022552818A1 (en) 2020-04-24 2024-03-25 Ashvattha Therapeutics Inc Dendrimer compositions and methods for treatment of severe acute respiratory distress syndrome
AU2021306781A1 (en) * 2020-07-10 2023-03-02 Jiangsu Hengrui Pharmaceuticals Co., Ltd. Sulfonylbenzamide derivative and conjugate thereof, preparation method therefor and use thereof
BR112023002855A2 (pt) * 2020-08-25 2023-04-25 Shanghai Senhui Medicine Co Ltd Macromolécula carregada com fármaco e método de preparação para a mesma
WO2022040761A1 (en) * 2020-08-31 2022-03-03 Starpharma Pty Ltd Dendrimer-drug conjugate

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US4289872A (en) * 1979-04-06 1981-09-15 Allied Corporation Macromolecular highly branched homogeneous compound based on lysine units
US4410688A (en) * 1981-04-29 1983-10-18 Allied Corporation Macromolecular highly branched homogeneous compound
US6720338B2 (en) 2000-09-20 2004-04-13 Abbott Laboratories N-acylsulfonamide apoptosis promoters
AR031130A1 (es) 2000-09-20 2003-09-10 Abbott Lab N-acilsulfonamidas promotoras de la apoptosis
WO2005049593A2 (en) 2003-11-13 2005-06-02 Abbott Laboratories N-acylsulfonamide apoptosis promoters
EP2757099B1 (en) 2005-05-12 2017-08-23 AbbVie Bahamas Limited Apoptosis promoters
CA2626865C (en) * 2005-10-25 2014-12-30 Starpharma Pty Limited Macromolecular compounds having controlled stoichiometry
CN101420962A (zh) * 2006-01-20 2009-04-29 星药股份有限公司 经修饰的大分子
PL2052011T3 (pl) * 2006-08-11 2021-03-08 Starpharma Pty Limited Nakierowany środek terapeutyczny będący dendrymerem polilizynowym
WO2008017122A1 (en) * 2006-08-11 2008-02-14 Starpharma Pty Ltd Polylysine dendrimer contrast agent
NZ577442A (en) 2006-11-15 2012-02-24 Genentech Inc Arylsulfonamide compounds
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WO2009158668A1 (en) 2008-06-26 2009-12-30 Prolynx Llc Prodrugs and drug-macromolecule conjugates having controlled drug release rates
US8216549B2 (en) * 2008-07-25 2012-07-10 National Health Research Institutes Method for making a ligand-quantum dot conjugate
DK2376480T3 (en) 2008-12-05 2016-09-12 Abbvie Inc Sulfonamide derivatives AS BCL-2-selective apoptosis inducing agents for the treatment of cancer and immune diseases
CA2929347A1 (en) 2009-05-26 2010-12-02 Milan Bruncko (hetero)aryl substituted sulfonyl-2-(1h-pyrrolo[2,3-b]pyridine-5-oxy)benzamide compounds and their use as apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
US8546399B2 (en) 2009-05-26 2013-10-01 Abbvie Inc. Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases
TWI540132B (zh) 2009-06-08 2016-07-01 亞培公司 Ｂｃｌ-２族群抑制劑之口服醫藥劑型
US20120269721A1 (en) * 2009-10-12 2012-10-25 The Regents Of The University Of California Targeted nanoclusters and methods of their use
WO2011140392A1 (en) 2010-05-05 2011-11-10 Prolynx Llc Controlled drug release from solid supports
US8703907B2 (en) 2010-05-05 2014-04-22 Prolynx Llc Controlled drug release from dendrimers
ES2584381T3 (es) 2010-05-05 2016-09-27 Prolynx Llc Liberación controlada de compuestos activos desde conjugados macromoleculares
TWI535712B (zh) 2010-08-06 2016-06-01 阿斯特捷利康公司 化合物
BR112013031556B1 (pt) * 2011-06-06 2022-03-29 Starpharma Pty Ltd Macromoléculas, uso das mesmas para tratar ou suprimir o crescimento de um câncer e composições farmacêuticas
WO2015035446A1 (en) * 2013-09-10 2015-03-19 Starpharma Pty Ltd Macromolecules of dendrimer-platinum conjugates
EP3152248B1 (en) * 2014-06-06 2019-10-09 Starpharma Pty Ltd Dendrimer-drug conjugates
TWI773730B (zh) * 2017-02-22 2022-08-11 瑞典商阿斯特捷利康公司 治療性樹枝狀聚合物
TWI831817B (zh) * 2018-08-17 2024-02-11 瑞典商阿斯特捷利康公司 治療癌症之方法
TWI856967B (zh) * 2018-08-17 2024-10-01 瑞典商阿斯特捷利康公司 樹枝狀體配製物

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