JP2020508334A5 - - Google Patents
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- JP2020508334A5 JP2020508334A5 JP2019546216A JP2019546216A JP2020508334A5 JP 2020508334 A5 JP2020508334 A5 JP 2020508334A5 JP 2019546216 A JP2019546216 A JP 2019546216A JP 2019546216 A JP2019546216 A JP 2019546216A JP 2020508334 A5 JP2020508334 A5 JP 2020508334A5
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762463353P | 2017-02-24 | 2017-02-24 | |
| US62/463,353 | 2017-02-24 | ||
| US201762597594P | 2017-12-12 | 2017-12-12 | |
| US62/597,594 | 2017-12-12 | ||
| PCT/US2018/019188 WO2018156740A1 (en) | 2017-02-24 | 2018-02-22 | Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020508334A JP2020508334A (ja) | 2020-03-19 |
| JP2020508334A5 true JP2020508334A5 (https=) | 2021-04-01 |
| JP7132232B2 JP7132232B2 (ja) | 2022-09-06 |
Family
ID=63252984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019546216A Active JP7132232B2 (ja) | 2017-02-24 | 2018-02-22 | Ｃｄ１３７及び腫瘍抗原に結合できる二重特異性結合分子並びにその使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US11459394B2 (https=) |
| EP (2) | EP3585431A4 (https=) |
| JP (1) | JP7132232B2 (https=) |
| KR (1) | KR102585848B1 (https=) |
| CN (1) | CN110325209A (https=) |
| AU (1) | AU2018224094B2 (https=) |
| BR (1) | BR112019017628A2 (https=) |
| CA (1) | CA3053803A1 (https=) |
| IL (1) | IL268836B2 (https=) |
| MA (1) | MA47612A (https=) |
| MX (1) | MX2019009967A (https=) |
| SG (1) | SG11201907753TA (https=) |
| TW (1) | TWI788327B (https=) |
| WO (1) | WO2018156740A1 (https=) |
| ZA (1) | ZA201905347B (https=) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3152235B1 (en) | 2014-05-29 | 2021-08-25 | MacroGenics, Inc. | Tri-specific binding molecules and methods of use thereof |
| EA201790719A1 (ru) * | 2014-09-26 | 2017-07-31 | Макродженикс, Инк. | Биспецифические моновалентные диатела, которые способны связывать cd19 и cd3, а также их применения |
| JP6882978B2 (ja) | 2014-10-29 | 2021-06-02 | バイスクルアールディー・リミテッド | Ｍｔ１−ｍｍｐに特異的な二環性ペプチドリガンド |
| TWI781098B (zh) | 2016-04-15 | 2022-10-21 | 美商宏觀基因股份有限公司 | 新穎的ｂ７-ｈ３-結合分子、其抗體藥物綴合物及其使用方法 |
| AU2017252233A1 (en) | 2016-04-22 | 2018-11-15 | Alligator Bioscience Ab | Novel bispecific polypeptides against CD137 |
| IL268836B2 (en) | 2017-02-24 | 2024-04-01 | Macrogenics Inc | Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof |
| JP7297672B2 (ja) | 2017-04-13 | 2023-06-26 | アジェナス インコーポレイテッド | 抗ｃｄ１３７抗体およびその使用方法 |
| JP7301757B2 (ja) | 2017-06-26 | 2023-07-03 | バイスクルアールディー・リミテッド | 検出可能部分を持つ二環式ペプチドリガンドおよびその使用 |
| SG11202000503QA (en) | 2017-07-20 | 2020-02-27 | Aptevo Res & Development Llc | Antigen binding proteins binding to 5t4 and 4-1bb and related compositions and methods |
| CN111183147B (zh) | 2017-08-04 | 2024-07-05 | 拜斯科技术开发有限公司 | Cd137特异性的双环肽配体 |
| TWI825046B (zh) | 2017-12-19 | 2023-12-11 | 英商拜西可泰克斯有限公司 | Epha2特用之雙環胜肽配位基 |
| JP2021514953A (ja) | 2018-02-23 | 2021-06-17 | バイスクルテクス・リミテッド | 多量体二環式ペプチドリガンド |
| GB201810316D0 (en) | 2018-06-22 | 2018-08-08 | Bicyclerd Ltd | Peptide ligands for binding to EphA2 |
| IL279489B2 (en) | 2018-06-22 | 2025-10-01 | Bicycletx Ltd | Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate |
| AU2019312200B2 (en) | 2018-07-23 | 2024-11-14 | Heidelberg Pharma Research Gmbh | Use of anti-CD137 antibody drug conjugate (ADC) in allogeneic cell therapy |
| WO2020051248A1 (en) * | 2018-09-05 | 2020-03-12 | Arizona Board Of Regents On Behalf Of Arizona State University | Oncolytic virus platform to treat hematological cancer |
| TWI839395B (zh) * | 2018-10-09 | 2024-04-21 | 瑞士商Ｎｕｍａｂ治療公司 | 靶向cd137的抗體及其使用方法 |
| CN112996809A (zh) * | 2018-10-10 | 2021-06-18 | 酵活有限公司 | 结合4-1bb和肿瘤相关抗原的抗体构建体以及其用途 |
| CA3118397A1 (en) * | 2018-11-01 | 2020-05-07 | Shandong Newtime Pharmaceutical Co., Ltd. | Bispecific antibody targeting cd3 and bcma, and uses thereof |
| GB201820288D0 (en) | 2018-12-13 | 2019-01-30 | Bicycle Tx Ltd | Bicycle peptide ligaands specific for MT1-MMP |
| GB201820295D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for MT1-MMP |
| GB201820325D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for psma |
| US12551567B2 (en) | 2018-12-21 | 2026-02-17 | Bicyclerd Limited | Bicyclic peptide ligands specific for PD-L1 |
| JP2022514618A (ja) | 2018-12-21 | 2022-02-14 | バイスクルテクス・リミテッド | Ｐｄ－ｌ１に特異的な二環式ペプチドリガンド |
| GB201900529D0 (en) | 2019-01-15 | 2019-03-06 | Bicycletx Ltd | Bicyclic peptide ligands specific for CD38 |
| SG11202110287QA (en) | 2019-04-24 | 2021-10-28 | Heidelberg Pharma Res Gmbh | Amatoxin antibody-drug conjugates and uses thereof |
| KR20220007098A (ko) | 2019-05-09 | 2022-01-18 | 바이사이클티엑스 리미티드 | Ox40에 특이적인 이환식 펩티드 리간드 |
| CA3285695A1 (en) * | 2019-06-26 | 2026-03-02 | Ap Biosciences, Inc. | Antibodies for t-cell activation |
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2018
- 2018-02-22 IL IL268836A patent/IL268836B2/en unknown
- 2018-02-22 EP EP18757875.2A patent/EP3585431A4/en not_active Withdrawn
- 2018-02-22 BR BR112019017628-4A patent/BR112019017628A2/pt unknown
- 2018-02-22 WO PCT/US2018/019188 patent/WO2018156740A1/en not_active Ceased
- 2018-02-22 MA MA047612A patent/MA47612A/fr unknown
- 2018-02-22 MX MX2019009967A patent/MX2019009967A/es unknown
- 2018-02-22 AU AU2018224094A patent/AU2018224094B2/en active Active
- 2018-02-22 SG SG11201907753TA patent/SG11201907753TA/en unknown
- 2018-02-22 CA CA3053803A patent/CA3053803A1/en active Pending
- 2018-02-22 CN CN201880013509.6A patent/CN110325209A/zh active Pending
- 2018-02-22 EP EP24171071.4A patent/EP4389226A3/en active Pending
- 2018-02-22 KR KR1020197027622A patent/KR102585848B1/ko active Active
- 2018-02-22 JP JP2019546216A patent/JP7132232B2/ja active Active
- 2018-02-22 US US16/488,025 patent/US11459394B2/en active Active
- 2018-02-23 TW TW107106261A patent/TWI788327B/zh not_active IP Right Cessation
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2019
- 2019-08-13 ZA ZA2019/05347A patent/ZA201905347B/en unknown
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2022
- 2022-08-08 US US17/883,158 patent/US11942149B2/en active Active
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- 2024-02-15 US US18/442,857 patent/US20240233818A1/en active Pending
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