JP2021523949A5 - - Google Patents
Info
- Publication number
- JP2021523949A5 JP2021523949A5 JP2021514466A JP2021514466A JP2021523949A5 JP 2021523949 A5 JP2021523949 A5 JP 2021523949A5 JP 2021514466 A JP2021514466 A JP 2021514466A JP 2021514466 A JP2021514466 A JP 2021514466A JP 2021523949 A5 JP2021523949 A5 JP 2021523949A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- antigen
- binding moiety
- amino acid
- seq
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862672602P | 2018-05-17 | 2018-05-17 | |
| US62/672,602 | 2018-05-17 | ||
| PCT/CN2019/087287 WO2019219064A1 (en) | 2018-05-17 | 2019-05-16 | Antibody binding pd-1 and use thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021523949A JP2021523949A (ja) | 2021-09-09 |
| JPWO2019219064A5 JPWO2019219064A5 (https=) | 2022-05-26 |
| JP2021523949A5 true JP2021523949A5 (https=) | 2022-05-26 |
| JP7535503B2 JP7535503B2 (ja) | 2024-08-16 |
Family
ID=68534222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021514466A Active JP7535503B2 (ja) | 2018-05-17 | 2019-05-16 | Ｐｄ－１に結合する抗体及びその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11136394B2 (https=) |
| EP (1) | EP3794039A4 (https=) |
| JP (1) | JP7535503B2 (https=) |
| KR (1) | KR20210010998A (https=) |
| CN (1) | CN112236455B (https=) |
| WO (1) | WO2019219064A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11802145B2 (en) | 2019-10-21 | 2023-10-31 | Nanjing Leads Biolabs Co., Ltd. | Recombinant protein targeting PD-1 and TGFß |
| BR112022023989A2 (pt) | 2020-05-26 | 2023-02-07 | Boehringer Ingelheim Int | Anticorpos anti-pd-1 |
| US11993654B2 (en) * | 2021-03-31 | 2024-05-28 | Merus N.V. | PD-1 binding domains |
| WO2023011654A1 (zh) * | 2021-08-06 | 2023-02-09 | 启愈生物技术(上海)有限公司 | 抗pd-1纳米抗体及其应用 |
| CN116685685A (zh) * | 2021-12-31 | 2023-09-01 | 南京维立志博生物科技有限公司 | Tigit单域抗体以及基于其的双特异性抗体 |
| CN118620082A (zh) * | 2023-03-10 | 2024-09-10 | 南京维立志博生物科技有限公司 | 靶向vegf途径和pd-1的双特异性抗原结合蛋白、其组合物和用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2494107C2 (ru) | 2005-05-09 | 2013-09-27 | Оно Фармасьютикал Ко., Лтд. | Моноклональные антитела человека к белку программируемой смерти 1 (pd-1) и способы лечения рака с использованием анти-pd-1-антител самостоятельно или в комбинации с другими иммунотерапевтическими средствами |
| CN104356236B (zh) * | 2005-07-01 | 2020-07-03 | E.R.施贵宝&圣斯有限责任公司 | 抗程序性死亡配体1(pd-l1)的人单克隆抗体 |
| CN104250302B (zh) * | 2013-06-26 | 2017-11-14 | 上海君实生物医药科技股份有限公司 | 抗pd‑1抗体及其应用 |
| EA034666B1 (ru) | 2013-09-13 | 2020-03-04 | Бейджин Свитзерланд Гмбх | Антитело против pd-1 и его применение для лечения рака или вирусной инфекции и фрагмент антитела |
| MY184154A (en) | 2013-12-12 | 2021-03-23 | Shanghai hengrui pharmaceutical co ltd | Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof |
| TWI681969B (zh) | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對ｐｄ-１的人類抗體 |
| KR102524920B1 (ko) * | 2014-07-22 | 2023-04-25 | 아폴로믹스 인코포레이티드 | 항-pd-1 항체 |
| EP3218409A2 (en) | 2014-11-11 | 2017-09-20 | Sutro Biopharma, Inc. | Anti-pd-1 antibodies, compositions comprising anti-pd-1 antibodies and methods of using anti-pd-1 antibodies |
| US20180222982A1 (en) * | 2015-07-29 | 2018-08-09 | Novartis Ag | Combination therapies comprising antibody molecules to pd-1 |
| WO2017024465A1 (en) | 2015-08-10 | 2017-02-16 | Innovent Biologics (Suzhou) Co., Ltd. | Pd-1 antibodies |
| MA43260A (fr) * | 2015-11-18 | 2018-09-26 | Merck Sharp & Dohme | Liants pd1 et/ou lag3 |
| US20210177896A1 (en) * | 2016-06-02 | 2021-06-17 | Novartis Ag | Therapeutic regimens for chimeric antigen receptor (car)- expressing cells |
-
2019
- 2019-05-16 CN CN201980033192.7A patent/CN112236455B/zh active Active
- 2019-05-16 US US16/414,724 patent/US11136394B2/en active Active
- 2019-05-16 WO PCT/CN2019/087287 patent/WO2019219064A1/en not_active Ceased
- 2019-05-16 JP JP2021514466A patent/JP7535503B2/ja active Active
- 2019-05-16 KR KR1020207035530A patent/KR20210010998A/ko active Pending
- 2019-05-16 EP EP19804070.1A patent/EP3794039A4/en active Pending
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