|
SE352811B
(enExample)
|
1971-06-04 |
1973-01-15 |
Pharmacia Ab |
|
|
US3960150A
(en)
|
1971-09-09 |
1976-06-01 |
Alza Corporation |
Bioerodible ocular device
|
|
US3867519A
(en)
|
1972-04-27 |
1975-02-18 |
Alza Corp |
Bioerodible drug delivery device
|
|
SE375007B
(enExample)
|
1972-11-30 |
1975-04-07 |
Pharmacia Ab |
|
|
US3963025A
(en)
|
1974-09-16 |
1976-06-15 |
Alza Corporation |
Ocular drug delivery device
|
|
JPS5825980B2
(ja)
|
1976-02-12 |
1983-05-31 |
ヤマサ醤油株式会社 |
サイクリックヌクレオチドの定量法
|
|
US4209514A
(en)
*
|
1977-06-24 |
1980-06-24 |
Ciba-Geigy Corporation |
3-Aminoalkyl-4-aryl-tetrahydroazepines
|
|
US4186184A
(en)
|
1977-12-27 |
1980-01-29 |
Alza Corporation |
Selective administration of drug with ocular therapeutic system
|
|
US4303637A
(en)
|
1980-04-04 |
1981-12-01 |
Alza Corporation |
Medication indicated for ocular hypertension
|
|
DK231088D0
(da)
|
1988-04-28 |
1988-04-28 |
Ferrosan As |
Piperidinforbindelser, deres fremstilling og anvendelse
|
|
CA1337418C
(en)
*
|
1988-03-28 |
1995-10-24 |
Engelbert Ciganek |
4-aryl-4-piperiding (or pyrrolidine or hexahydroazepine) carbinols and heterocyclic analogs thereof
|
|
US5086063A
(en)
*
|
1988-03-28 |
1992-02-04 |
Du Pont Merck Pharmaceutical Company |
4-aryl-4-piperidine (or pyrrolidine or hexahydroazepine) carbinols and heterocyclic analogs thereof
|
|
US5401629A
(en)
|
1990-08-07 |
1995-03-28 |
The Salk Institute Biotechnology/Industrial Associates, Inc. |
Assay methods and compositions useful for measuring the transduction of an intracellular signal
|
|
US5443505A
(en)
|
1993-11-15 |
1995-08-22 |
Oculex Pharmaceuticals, Inc. |
Biocompatible ocular implants
|
|
US5869079A
(en)
|
1995-06-02 |
1999-02-09 |
Oculex Pharmaceuticals, Inc. |
Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
|
|
DE69633527T2
(de)
|
1995-12-04 |
2006-02-16 |
Tosoh Corp., Shinnanyo |
Verfahren zur Herstellung von Benzylalkohol
|
|
HUP9902160A3
(en)
|
1996-03-29 |
2001-02-28 |
Pfizer |
Benzyl(idene)-lactam derivatives, their use as selective (ant)agonists of 5-ht1a-and/or 5-ht1d receptors, pharmaceutical compositions containing these compounds
|
|
JP2000513375A
(ja)
|
1996-06-28 |
2000-10-10 |
メルク エンド カンパニー インコーポレーテッド |
フィブリノーゲンレセプター拮抗薬プロドラッグ
|
|
WO1998006694A1
(en)
|
1996-08-16 |
1998-02-19 |
Du Pont Pharmaceuticals Company |
Amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof
|
|
AU4727799A
(en)
*
|
1998-06-30 |
2000-01-17 |
Eli Lilly And Company |
Azepine derivatives having effects on serotonin related systems
|
|
TR200102911T2
(tr)
|
1999-04-09 |
2002-01-21 |
Astrazeneca Ab |
Adamantan türevleri.
|
|
AU1018801A
(en)
|
1999-10-29 |
2001-05-14 |
Novo Nordisk A/S |
Use of 3,4-substituted piperidines
|
|
GB0015562D0
(en)
|
2000-06-23 |
2000-08-16 |
Pfizer Ltd |
Heterocycles
|
|
AU2001273040A1
(en)
|
2000-06-27 |
2002-01-08 |
Du Pont Pharmaceuticals Company |
Factor xa inhibitors
|
|
US20020077323A1
(en)
|
2000-07-12 |
2002-06-20 |
Mclean Stafford |
Use of delta opioid receptor ligands and serotonin reuptake inhibitors in the treatment of chemical dependencies
|
|
US6476046B1
(en)
|
2000-12-04 |
2002-11-05 |
Sepracor, Inc. |
Diazabicyclo[4.3.0]nonanes, and methods of use thereof
|
|
ES2194588B1
(es)
|
2001-07-13 |
2004-10-16 |
Astur Pharma S.A. |
Precursores opticamente puros de paroxetina.
|
|
US6995144B2
(en)
|
2002-03-14 |
2006-02-07 |
Eisai Co., Ltd. |
Nitrogen containing heterocyclic compounds and medicines containing the same
|
|
PT2208727E
(pt)
|
2002-09-19 |
2012-10-11 |
Lilly Co Eli |
Éteres diarílicos como antagonista do receptor opióide
|
|
JP2006517567A
(ja)
|
2003-02-12 |
2006-07-27 |
ニューロサーチ、アクティーゼルスカブ |
新規８−アザ−ビシクロ［３．２．１］オクタン誘導体及びこれをモノアミン神経伝達物質再取り込み阻害薬として使用する方法
|
|
DE10308350B4
(de)
|
2003-02-27 |
2006-06-01 |
Sanofi-Aventis Deutschland Gmbh |
Verfahren zur Herstellung der enantiomeren Formen von cis-konfigurierten 1,3-Cyclohexandiol-Derivaten
|
|
WO2005012716A1
(en)
|
2003-07-25 |
2005-02-10 |
Siemens Vdo Automotive Inc. |
Integrated vapor control valve and sensor
|
|
JP2007507504A
(ja)
|
2003-09-30 |
2007-03-29 |
メルク エンド カムパニー インコーポレーテッド |
フェニルピロリジンエーテル系タキキニン受容体拮抗薬
|
|
GB0327740D0
(en)
|
2003-11-28 |
2003-12-31 |
Glaxo Group Ltd |
Novel compounds
|
|
WO2005068427A1
(ja)
|
2004-01-14 |
2005-07-28 |
Takeda Pharmaceutical Company Limited |
カルボキサミド誘導体およびその用途
|
|
KR20070015544A
(ko)
|
2004-04-14 |
2007-02-05 |
와이어쓰 |
라파마이신 42-에스테르 유도체의 위치특이성 합성
|
|
CA2569611C
(en)
|
2004-06-21 |
2012-12-11 |
F. Hoffmann-La Roche Ag |
Indole derivatives as histamine receptor antagonists
|
|
DE602005023172D1
(de)
|
2004-07-16 |
2010-10-07 |
Schering Corp |
Hydantoinderivate zur behandlung von entzündlichen erkrankungen
|
|
US7488745B2
(en)
|
2004-07-16 |
2009-02-10 |
Schering Corporation |
Compounds for the treatment of inflammatory disorders
|
|
US7504424B2
(en)
|
2004-07-16 |
2009-03-17 |
Schering Corporation |
Compounds for the treatment of inflammatory disorders
|
|
US7098203B2
(en)
|
2004-07-20 |
2006-08-29 |
Bristol-Myers Squibb Company |
Homopiperidine derivatives as NK-1 antagonists
|
|
US7138423B2
(en)
|
2004-07-20 |
2006-11-21 |
Bristol-Myers Squibb Company |
Arylpyrrolidine derivatives as NK-1 /SSRI antagonists
|
|
GB0519957D0
(en)
|
2005-09-30 |
2005-11-09 |
Sb Pharmco Inc |
Chemical compound
|
|
US7872023B2
(en)
|
2005-02-17 |
2011-01-18 |
Research Triangle Institute |
Kappa opioid receptor ligands
|
|
TW200804307A
(en)
|
2005-10-27 |
2008-01-16 |
Synta Pharmaceuticals Corp |
Process for preparing mesylate salts of IL-12 inhibitory compounds
|
|
CA2631221C
(en)
|
2005-12-01 |
2014-06-03 |
F. Hoffmann-La Roche Ag |
Serotonin transporter (sert) inhibitors
|
|
US20070142389A1
(en)
|
2005-12-20 |
2007-06-21 |
Pfizer Inc. |
Piperidine derivatives
|
|
AU2007225208A1
(en)
|
2006-03-14 |
2007-09-20 |
Amgen Inc. |
Bicyclic carboxylic acid derivatives useful for treating metabolic disorders
|
|
WO2008012623A1
(en)
|
2006-07-25 |
2008-01-31 |
Pfizer Products Inc. |
Benzimidazolyl compounds as potentiators of mglur2 subtype of glutamate receptor
|
|
US8470361B2
(en)
|
2006-12-04 |
2013-06-25 |
Orexo Ab |
Non-abusable pharmaceutical composition comprising opioids
|
|
WO2008139484A2
(en)
|
2007-05-16 |
2008-11-20 |
R. L. Fine Chem |
New process for the synthesis of loferpramine maleate: a stable salt of loferpramine
|
|
KR20100017372A
(ko)
|
2007-05-25 |
2010-02-16 |
애보트 게엠베하 운트 콤파니 카게 |
향대사성 글루타메이트 수용체 2（ｍｇｌｕ2 수용체）의 포지티브 조절자로서의 헤테로사이클릭 화합물
|
|
US8962841B2
(en)
|
2007-06-29 |
2015-02-24 |
Brock University |
Methods for one-pot N-demethylation/N-functionalization of morphine and tropane alkaloids
|
|
JP2010535733A
(ja)
|
2007-08-07 |
2010-11-25 |
エフ．ホフマン−ラ ロシュ アーゲー |
Ｎｋ３受容体アンタゴニストとしてのピロリジンアリールエーテル
|
|
AU2008290634B2
(en)
|
2007-08-22 |
2012-12-06 |
F. Hoffmann-La Roche Ag |
Pyrrolidine aryl-ether as NK3 receptor antagonists
|
|
GB0721178D0
(en)
*
|
2007-10-29 |
2007-12-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
EA201000808A1
(ru)
|
2007-11-16 |
2011-04-29 |
Ньюраксон, Инк. |
Индольные соединения и способы лечения висцеральной боли
|
|
WO2009072643A1
(en)
|
2007-12-03 |
2009-06-11 |
Takeda Pharmaceutical Company Limited |
Nitrogen-containing heterocyclic compound and use thereof
|
|
US8394834B2
(en)
|
2009-08-25 |
2013-03-12 |
Hoffman-La Roche Inc. |
Pyrrolidines as NK3 receptor antagonists
|
|
BR112012010253A8
(pt)
|
2009-10-30 |
2016-10-04 |
Janssen Pharmaceutica Nv |
compostos de pirimidina como moduladores do receptor delta opioide
|
|
CN102753528A
(zh)
|
2009-12-04 |
2012-10-24 |
霍夫曼-拉罗奇有限公司 |
作为单胺重摄取抑制剂的二苯基氮杂*衍生物
|
|
US8664214B2
(en)
|
2010-03-30 |
2014-03-04 |
AbbVie Deutschland GmbH & Co. KG |
Small molecule potentiators of metabotropic glutamate receptors I
|
|
US8507535B2
(en)
|
2010-07-07 |
2013-08-13 |
Hoffmann-La Roche Inc. |
Methyl-pyrrolidine ether derivatives
|
|
WO2012075232A1
(en)
|
2010-12-04 |
2012-06-07 |
Trevena, Inc. |
Opioid receptor ligands and methods of using and making the same
|
|
ES2716865T3
(es)
|
2011-02-18 |
2019-06-17 |
Scripps Research Inst |
Diferenciación dirigida de células precursoras de oligodendrocitos a un destino celular mielinizante
|
|
ME02754B
(me)
*
|
2011-03-23 |
2018-01-20 |
Trevena Inc |
Ligandi opioidnih receptora i postupci njihove upotrebe i pripreme
|
|
WO2012129562A2
(en)
|
2011-03-24 |
2012-09-27 |
The Scripps Research Institute |
Compounds and methods for inducing chondrogenesis
|
|
JP2014159375A
(ja)
|
2011-06-15 |
2014-09-04 |
Takeda Chem Ind Ltd |
アゼパン化合物
|
|
US9168254B2
(en)
|
2011-10-14 |
2015-10-27 |
Array Biopharma Inc. |
Polymorphs of ARRY-380, a selective HER 2 inhibitor and pharmaceutical compositions containing them
|
|
ES2586213T3
(es)
|
2011-10-31 |
2016-10-13 |
Xenon Pharmaceuticals Inc. |
Compuestos de bencenosulfonamida y su uso como agentes terapéuticos
|
|
EP2810942B1
(en)
|
2012-01-31 |
2016-03-30 |
Eisai R&D Management Co., Ltd. |
Paroxetine derivative
|
|
WO2013182612A1
(en)
|
2012-06-07 |
2013-12-12 |
Bayer Pharma Aktiengesellschaft |
Glucose transport inhibitors
|
|
JP6250668B2
(ja)
*
|
2012-08-10 |
2017-12-20 |
ヤンセン・サイエンシズ・アイルランド・ユーシー |
新しい抗菌化合物
|
|
BR112015022758A2
(pt)
|
2013-03-15 |
2017-07-18 |
Abbvie Deutschland |
derivados de pirrolidina, composições farmacêuticas contendo os mesmos e seu uso em terapia
|
|
WO2016029218A1
(en)
*
|
2014-08-22 |
2016-02-25 |
The Arizona Board Of Regents On Behalf Of The University Of Arizona |
Substituted 1-arylethyl-4-acylaminopiperidine derivatives as opioid/alpha-adrenoreceptor modulators and method of their preparation
|
|
WO2016210403A1
(en)
|
2015-06-26 |
2016-12-29 |
The Regents Of The University Of Michigan |
G protein-coupled receptor kinase inhibitors and methods for use of the same
|
|
MA43313B1
(fr)
|
2015-09-02 |
2022-06-30 |
Trevena Inc |
Aza-hétérocyclique à 6 éléments contenant des composés modulateurs de récepteurs opioïdes delta, et leurs procédés de fabrication et d'utilisation
|
|
CN110446495B
(zh)
|
2017-02-17 |
2023-09-05 |
特维娜有限公司 |
含有7元氮杂杂环的δ阿片受体调节化合物及其使用和制备方法
|
|
CN110520129A
(zh)
|
2017-02-17 |
2019-11-29 |
特维娜有限公司 |
含有5元氮杂杂环的δ阿片受体调节化合物及其使用和制备方法
|
|
CN110831593A
(zh)
*
|
2017-06-14 |
2020-02-21 |
特维娜有限公司 |
用于调节s1p1活性的化合物及其使用方法
|
|
MX2020007152A
(es)
|
2017-10-18 |
2020-12-10 |
Epizyme Inc |
Compuestos heterociclicos sustituidos con amina como inhibidores de ehmt2, sales de los mismos, y metodos de sintesis de los mismos.
|
|
CN111138425A
(zh)
|
2020-01-06 |
2020-05-12 |
中国药科大学 |
三氮唑类衍生物及其制备方法与用途
|
|
CN116406268A
(zh)
|
2020-10-27 |
2023-07-07 |
特维娜有限公司 |
δ-阿片样物质调节剂的结晶和无定形形式
|
|
WO2023070605A1
(en)
|
2021-10-29 |
2023-05-04 |
Trevena, Inc. |
Methods of preparing 6-membered aza-heterocyclic containing delta-opioid receptor modulating compounds
|