|
SE352811B
(enExample)
|
1971-06-04 |
1973-01-15 |
Pharmacia Ab |
|
|
US3960150A
(en)
|
1971-09-09 |
1976-06-01 |
Alza Corporation |
Bioerodible ocular device
|
|
US3867519A
(en)
|
1972-04-27 |
1975-02-18 |
Alza Corp |
Bioerodible drug delivery device
|
|
SE375007B
(enExample)
|
1972-11-30 |
1975-04-07 |
Pharmacia Ab |
|
|
US3963025A
(en)
|
1974-09-16 |
1976-06-15 |
Alza Corporation |
Ocular drug delivery device
|
|
JPS5825980B2
(ja)
|
1976-02-12 |
1983-05-31 |
ヤマサ醤油株式会社 |
サイクリックヌクレオチドの定量法
|
|
US4209514A
(en)
|
1977-06-24 |
1980-06-24 |
Ciba-Geigy Corporation |
3-Aminoalkyl-4-aryl-tetrahydroazepines
|
|
US4186184A
(en)
|
1977-12-27 |
1980-01-29 |
Alza Corporation |
Selective administration of drug with ocular therapeutic system
|
|
US4303637A
(en)
|
1980-04-04 |
1981-12-01 |
Alza Corporation |
Medication indicated for ocular hypertension
|
|
DK231088D0
(da)
|
1988-04-28 |
1988-04-28 |
Ferrosan As |
Piperidinforbindelser, deres fremstilling og anvendelse
|
|
US5086063A
(en)
|
1988-03-28 |
1992-02-04 |
Du Pont Merck Pharmaceutical Company |
4-aryl-4-piperidine (or pyrrolidine or hexahydroazepine) carbinols and heterocyclic analogs thereof
|
|
CA1337418C
(en)
|
1988-03-28 |
1995-10-24 |
Engelbert Ciganek |
4-aryl-4-piperiding (or pyrrolidine or hexahydroazepine) carbinols and heterocyclic analogs thereof
|
|
US5401629A
(en)
|
1990-08-07 |
1995-03-28 |
The Salk Institute Biotechnology/Industrial Associates, Inc. |
Assay methods and compositions useful for measuring the transduction of an intracellular signal
|
|
US5443505A
(en)
|
1993-11-15 |
1995-08-22 |
Oculex Pharmaceuticals, Inc. |
Biocompatible ocular implants
|
|
US5869079A
(en)
|
1995-06-02 |
1999-02-09 |
Oculex Pharmaceuticals, Inc. |
Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
|
|
ES2246058T3
(es)
|
1996-03-29 |
2006-02-01 |
Pfizer Inc. |
Derivados bencil(iden)-lactama, su preparacion y su uso como (ant)agonistas selectivos de receptores 5-ht1a y/o 5-ht1d.
|
|
JP2000513375A
(ja)
|
1996-06-28 |
2000-10-10 |
メルク エンド カンパニー インコーポレーテッド |
フィブリノーゲンレセプター拮抗薬プロドラッグ
|
|
AU4064597A
(en)
|
1996-08-16 |
1998-03-06 |
Du Pont Pharmaceuticals Company |
Amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof
|
|
EP1091741A4
(en)
|
1998-06-30 |
2002-12-18 |
Lilly Co Eli |
AZEPINE DERIVATIVES PLAYING A ROLE IN SEROTONIN ASSOCIATED SYSTEMS
|
|
TR200102911T2
(tr)
|
1999-04-09 |
2002-01-21 |
Astrazeneca Ab |
Adamantan türevleri.
|
|
AU1018801A
(en)
|
1999-10-29 |
2001-05-14 |
Novo Nordisk A/S |
Use of 3,4-substituted piperidines
|
|
GB0015562D0
(en)
|
2000-06-23 |
2000-08-16 |
Pfizer Ltd |
Heterocycles
|
|
WO2002000651A2
(en)
|
2000-06-27 |
2002-01-03 |
Bristol-Myers Squibb Pharma Company |
Factor xa inhibitors
|
|
US20020077323A1
(en)
|
2000-07-12 |
2002-06-20 |
Mclean Stafford |
Use of delta opioid receptor ligands and serotonin reuptake inhibitors in the treatment of chemical dependencies
|
|
US6476046B1
(en)
|
2000-12-04 |
2002-11-05 |
Sepracor, Inc. |
Diazabicyclo[4.3.0]nonanes, and methods of use thereof
|
|
US6995144B2
(en)
|
2002-03-14 |
2006-02-07 |
Eisai Co., Ltd. |
Nitrogen containing heterocyclic compounds and medicines containing the same
|
|
ES2392200T3
(es)
|
2002-09-19 |
2012-12-05 |
Eli Lilly & Company |
Ésteres de diarilo como antagonistas del receptor opiáceo
|
|
EP1594874A1
(en)
|
2003-02-12 |
2005-11-16 |
Neurosearch A/S |
Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
|
|
WO2005012716A1
(en)
|
2003-07-25 |
2005-02-10 |
Siemens Vdo Automotive Inc. |
Integrated vapor control valve and sensor
|
|
EP1670476A4
(en)
|
2003-09-30 |
2009-05-27 |
Merck & Co Inc |
Phenylpyrrolidine-ETHER-tachykinin receptor Antagonist
|
|
WO2005068427A1
(ja)
|
2004-01-14 |
2005-07-28 |
Takeda Pharmaceutical Company Limited |
カルボキサミド誘導体およびその用途
|
|
CN1972926B
(zh)
|
2004-06-21 |
2011-02-16 |
霍夫曼-拉罗奇有限公司 |
作为组胺受体拮抗剂的吲哚衍生物
|
|
US7488745B2
(en)
|
2004-07-16 |
2009-02-10 |
Schering Corporation |
Compounds for the treatment of inflammatory disorders
|
|
EP1778676B1
(en)
|
2004-07-16 |
2010-08-25 |
Schering Corporation |
Hydantoin derivatives for the treatment of inflammatory disorders
|
|
US7504424B2
(en)
|
2004-07-16 |
2009-03-17 |
Schering Corporation |
Compounds for the treatment of inflammatory disorders
|
|
US7138423B2
(en)
*
|
2004-07-20 |
2006-11-21 |
Bristol-Myers Squibb Company |
Arylpyrrolidine derivatives as NK-1 /SSRI antagonists
|
|
US7098203B2
(en)
|
2004-07-20 |
2006-08-29 |
Bristol-Myers Squibb Company |
Homopiperidine derivatives as NK-1 antagonists
|
|
US7872023B2
(en)
|
2005-02-17 |
2011-01-18 |
Research Triangle Institute |
Kappa opioid receptor ligands
|
|
TW200804307A
(en)
|
2005-10-27 |
2008-01-16 |
Synta Pharmaceuticals Corp |
Process for preparing mesylate salts of IL-12 inhibitory compounds
|
|
ATE434605T1
(de)
|
2005-12-01 |
2009-07-15 |
Hoffmann La Roche |
Inhibitoren des serotonintransporters (sert)
|
|
US20070142389A1
(en)
|
2005-12-20 |
2007-06-21 |
Pfizer Inc. |
Piperidine derivatives
|
|
JP2009530281A
(ja)
|
2006-03-14 |
2009-08-27 |
アムジエン・インコーポレーテツド |
代謝障害の治療に有用である二環式カルボン酸誘導体
|
|
WO2008012623A1
(en)
|
2006-07-25 |
2008-01-31 |
Pfizer Products Inc. |
Benzimidazolyl compounds as potentiators of mglur2 subtype of glutamate receptor
|
|
US8470361B2
(en)
|
2006-12-04 |
2013-06-25 |
Orexo Ab |
Non-abusable pharmaceutical composition comprising opioids
|
|
AU2008257559B2
(en)
|
2007-05-25 |
2013-10-10 |
AbbVie Deutschland GmbH & Co. KG |
Heterocyclic compounds as positive modulators of metabotropic glutamate receptor 2 (MGLU2 receptor)
|
|
MX2010001080A
(es)
|
2007-08-07 |
2010-03-01 |
Hoffmann La Roche |
Pirrolidin-aril-eteres como antagonistas de receptor de nk3.
|
|
ATE519738T1
(de)
|
2007-08-22 |
2011-08-15 |
Hoffmann La Roche |
Pyrrolidinarylether als nk3-rezeptorantagonisten
|
|
GB0721178D0
(en)
|
2007-10-29 |
2007-12-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
JP2011503120A
(ja)
|
2007-11-16 |
2011-01-27 |
ニューラクソン，インコーポレーテッド |
内臓痛を治療するためのインドール化合物および方法
|
|
CL2008003595A1
(es)
*
|
2007-12-03 |
2009-11-20 |
Takeda Pharmaceuticals Co |
Compuestos heterociclicos nitrogenados, antagonistas del receptor de taquiquinina; agente farmaceutico que comprende el compuesto; y uso en la profilaxis o el tratamiento de una enfermedad del tracto urinario inferior, una enfermedad gastrointestinal o una enfermedad del sistema nervioso central.
|
|
US8394834B2
(en)
|
2009-08-25 |
2013-03-12 |
Hoffman-La Roche Inc. |
Pyrrolidines as NK3 receptor antagonists
|
|
AU2010313401B2
(en)
|
2009-10-30 |
2015-07-23 |
Janssen Pharmaceutica Nv |
Pyrimidine compounds as delta opioid receptor modulators
|
|
BR112012012905A2
(pt)
|
2009-12-04 |
2017-03-01 |
Hoffmann La Roche |
derivados de difenil azepina como inibidores da reabsorção de monoamina
|
|
US8664214B2
(en)
|
2010-03-30 |
2014-03-04 |
AbbVie Deutschland GmbH & Co. KG |
Small molecule potentiators of metabotropic glutamate receptors I
|
|
US8507535B2
(en)
*
|
2010-07-07 |
2013-08-13 |
Hoffmann-La Roche Inc. |
Methyl-pyrrolidine ether derivatives
|
|
WO2012075232A1
(en)
|
2010-12-04 |
2012-06-07 |
Trevena, Inc. |
Opioid receptor ligands and methods of using and making the same
|
|
JP6133790B2
(ja)
|
2011-02-18 |
2017-05-24 |
ザ スクリプス リサーチ インスティテュート |
ミエリン形成細胞運命へのオリゴデンドロサイト前駆細胞の定方向分化
|
|
PL3290415T3
(pl)
|
2011-03-23 |
2021-07-19 |
Trevena, Inc. |
Ligandy receptora opioidowego oraz sposoby ich stosowania i wytwarzania
|
|
US9464065B2
(en)
|
2011-03-24 |
2016-10-11 |
The Scripps Research Institute |
Compounds and methods for inducing chondrogenesis
|
|
JP2014159375A
(ja)
|
2011-06-15 |
2014-09-04 |
Takeda Chem Ind Ltd |
アゼパン化合物
|
|
US9630929B2
(en)
|
2011-10-31 |
2017-04-25 |
Xenon Pharmaceuticals Inc. |
Benzenesulfonamide compounds and their use as therapeutic agents
|
|
WO2013182612A1
(en)
|
2012-06-07 |
2013-12-12 |
Bayer Pharma Aktiengesellschaft |
Glucose transport inhibitors
|
|
WO2014023815A1
(en)
|
2012-08-10 |
2014-02-13 |
Janssen R&D Ireland |
New antibacterial compounds
|
|
CA2900888A1
(en)
|
2013-03-15 |
2014-09-18 |
AbbVie Deutschland GmbH & Co. KG |
Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
|
|
US9765027B2
(en)
|
2014-08-22 |
2017-09-19 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Substituted 1-arylethyl-4-acylaminopiperidine derivatives as opioid/alpha-adrenoreceptor modulators and method of their preparation
|
|
EP3313396B1
(en)
|
2015-06-26 |
2021-12-15 |
The Regents of The University of Michigan |
G protein-coupled receptor kinase inhibitors and methods for use of the same
|
|
EP3344248B1
(en)
|
2015-09-02 |
2022-03-23 |
Trevena, Inc. |
6-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same
|
|
CA3052480A1
(en)
|
2017-02-17 |
2018-08-23 |
Trevena, Inc. |
5-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same
|
|
CN110446495B
(zh)
|
2017-02-17 |
2023-09-05 |
特维娜有限公司 |
含有7元氮杂杂环的δ阿片受体调节化合物及其使用和制备方法
|