|
SE352811B
(https=)
|
1971-06-04 |
1973-01-15 |
Pharmacia Ab |
|
|
US3960150A
(en)
|
1971-09-09 |
1976-06-01 |
Alza Corporation |
Bioerodible ocular device
|
|
US3867519A
(en)
|
1972-04-27 |
1975-02-18 |
Alza Corp |
Bioerodible drug delivery device
|
|
SE375007B
(https=)
|
1972-11-30 |
1975-04-07 |
Pharmacia Ab |
|
|
US3963025A
(en)
|
1974-09-16 |
1976-06-15 |
Alza Corporation |
Ocular drug delivery device
|
|
JPS5825980B2
(ja)
|
1976-02-12 |
1983-05-31 |
ヤマサ醤油株式会社 |
サイクリックヌクレオチドの定量法
|
|
US4209514A
(en)
|
1977-06-24 |
1980-06-24 |
Ciba-Geigy Corporation |
3-Aminoalkyl-4-aryl-tetrahydroazepines
|
|
US4186184A
(en)
|
1977-12-27 |
1980-01-29 |
Alza Corporation |
Selective administration of drug with ocular therapeutic system
|
|
US4303637A
(en)
|
1980-04-04 |
1981-12-01 |
Alza Corporation |
Medication indicated for ocular hypertension
|
|
DK231088D0
(da)
|
1988-04-28 |
1988-04-28 |
Ferrosan As |
Piperidinforbindelser, deres fremstilling og anvendelse
|
|
US5086063A
(en)
|
1988-03-28 |
1992-02-04 |
Du Pont Merck Pharmaceutical Company |
4-aryl-4-piperidine (or pyrrolidine or hexahydroazepine) carbinols and heterocyclic analogs thereof
|
|
CA1337418C
(en)
|
1988-03-28 |
1995-10-24 |
Engelbert Ciganek |
4-aryl-4-piperiding (or pyrrolidine or hexahydroazepine) carbinols and heterocyclic analogs thereof
|
|
US5401629A
(en)
|
1990-08-07 |
1995-03-28 |
The Salk Institute Biotechnology/Industrial Associates, Inc. |
Assay methods and compositions useful for measuring the transduction of an intracellular signal
|
|
US5443505A
(en)
|
1993-11-15 |
1995-08-22 |
Oculex Pharmaceuticals, Inc. |
Biocompatible ocular implants
|
|
US5869079A
(en)
|
1995-06-02 |
1999-02-09 |
Oculex Pharmaceuticals, Inc. |
Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents
|
|
EA001485B1
(ru)
|
1996-03-29 |
2001-04-23 |
Пфайзер Инк. |
Производные бензил(иден)-лактамов, их получение и применение в качестве селективных (ант)агонистов рецепторов 5-htи/или 5-ht
|
|
JP2000513375A
(ja)
|
1996-06-28 |
2000-10-10 |
メルク エンド カンパニー インコーポレーテッド |
フィブリノーゲンレセプター拮抗薬プロドラッグ
|
|
DE69718194T2
(de)
|
1996-08-16 |
2003-10-16 |
Bristol-Myers Squibb Pharma Co., Wilmington |
Amidinophenyl-pyrrolidine, -pyrroline und -isoxazolidine und ihre derivate
|
|
AU4727799A
(en)
|
1998-06-30 |
2000-01-17 |
Eli Lilly And Company |
Azepine derivatives having effects on serotonin related systems
|
|
CZ20013608A3
(cs)
|
1999-04-09 |
2002-05-15 |
Astrazeneca Ab |
Adamantanové deriváty
|
|
AU1018801A
(en)
|
1999-10-29 |
2001-05-14 |
Novo Nordisk A/S |
Use of 3,4-substituted piperidines
|
|
GB0015562D0
(en)
|
2000-06-23 |
2000-08-16 |
Pfizer Ltd |
Heterocycles
|
|
AU2001273040A1
(en)
|
2000-06-27 |
2002-01-08 |
Du Pont Pharmaceuticals Company |
Factor xa inhibitors
|
|
US20020077323A1
(en)
|
2000-07-12 |
2002-06-20 |
Mclean Stafford |
Use of delta opioid receptor ligands and serotonin reuptake inhibitors in the treatment of chemical dependencies
|
|
US6476046B1
(en)
|
2000-12-04 |
2002-11-05 |
Sepracor, Inc. |
Diazabicyclo[4.3.0]nonanes, and methods of use thereof
|
|
US6995144B2
(en)
|
2002-03-14 |
2006-02-07 |
Eisai Co., Ltd. |
Nitrogen containing heterocyclic compounds and medicines containing the same
|
|
KR101025633B1
(ko)
|
2002-09-19 |
2011-03-30 |
일라이 릴리 앤드 캄파니 |
오피오이드 수용체 안타고니스트로서의 디아릴 에테르
|
|
CA2515732A1
(en)
|
2003-02-12 |
2004-08-26 |
Neurosearch A/S |
Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
|
|
WO2005012716A1
(en)
|
2003-07-25 |
2005-02-10 |
Siemens Vdo Automotive Inc. |
Integrated vapor control valve and sensor
|
|
AU2004277932B2
(en)
|
2003-09-30 |
2009-07-16 |
Merck & Co., Inc. |
Phenyl pyrrolidine ether tachykinin receptor antagonists
|
|
WO2005068427A1
(ja)
|
2004-01-14 |
2005-07-28 |
Takeda Pharmaceutical Company Limited |
カルボキサミド誘導体およびその用途
|
|
RU2382778C2
(ru)
|
2004-06-21 |
2010-02-27 |
Ф.Хоффманн-Ля Рош Аг |
Производные индола в качестве антагонистов гистаминовых рецепторов
|
|
KR20070032787A
(ko)
|
2004-07-16 |
2007-03-22 |
쉐링 코포레이션 |
염증 질환 치료용 히단토인 유도체
|
|
US7488745B2
(en)
|
2004-07-16 |
2009-02-10 |
Schering Corporation |
Compounds for the treatment of inflammatory disorders
|
|
US7504424B2
(en)
|
2004-07-16 |
2009-03-17 |
Schering Corporation |
Compounds for the treatment of inflammatory disorders
|
|
US7138423B2
(en)
|
2004-07-20 |
2006-11-21 |
Bristol-Myers Squibb Company |
Arylpyrrolidine derivatives as NK-1 /SSRI antagonists
|
|
US7098203B2
(en)
|
2004-07-20 |
2006-08-29 |
Bristol-Myers Squibb Company |
Homopiperidine derivatives as NK-1 antagonists
|
|
US7872023B2
(en)
|
2005-02-17 |
2011-01-18 |
Research Triangle Institute |
Kappa opioid receptor ligands
|
|
TW200804307A
(en)
|
2005-10-27 |
2008-01-16 |
Synta Pharmaceuticals Corp |
Process for preparing mesylate salts of IL-12 inhibitory compounds
|
|
EP1957450B1
(en)
|
2005-12-01 |
2009-06-24 |
F.Hoffmann-La Roche Ag |
Serotonin transporter (sert) inhibitors
|
|
US20070142389A1
(en)
|
2005-12-20 |
2007-06-21 |
Pfizer Inc. |
Piperidine derivatives
|
|
MX2008011615A
(es)
|
2006-03-14 |
2008-09-22 |
Amgen Inc |
Derivados de acidos carboxilicos biciclicos utiles para tratar trastornos metabolicos.
|
|
WO2008012623A1
(en)
|
2006-07-25 |
2008-01-31 |
Pfizer Products Inc. |
Benzimidazolyl compounds as potentiators of mglur2 subtype of glutamate receptor
|
|
ES2439581T3
(es)
|
2006-12-04 |
2014-01-23 |
Orexo Ab |
Nueva composición farmacéutica no susceptible de abuso que comprende opioides
|
|
EP2167464B1
(en)
|
2007-05-25 |
2014-12-03 |
AbbVie Deutschland GmbH & Co KG |
Heterocyclic compounds as positive modulators of metabotropic glutamate receptor 2 (mglu2 receptor)
|
|
CN101778837A
(zh)
|
2007-08-07 |
2010-07-14 |
弗·哈夫曼-拉罗切有限公司 |
作为nk3受体拮抗剂的吡咯烷芳基-醚
|
|
ATE519738T1
(de)
|
2007-08-22 |
2011-08-15 |
Hoffmann La Roche |
Pyrrolidinarylether als nk3-rezeptorantagonisten
|
|
GB0721178D0
(en)
|
2007-10-29 |
2007-12-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
EA201000808A1
(ru)
|
2007-11-16 |
2011-04-29 |
Ньюраксон, Инк. |
Индольные соединения и способы лечения висцеральной боли
|
|
AR069526A1
(es)
|
2007-12-03 |
2010-01-27 |
Takeda Pharmaceutical |
Compuesto heterociclico que contiene nitrogeno y su uso
|
|
US8394834B2
(en)
|
2009-08-25 |
2013-03-12 |
Hoffman-La Roche Inc. |
Pyrrolidines as NK3 receptor antagonists
|
|
CN102741240B
(zh)
|
2009-10-30 |
2015-05-06 |
詹森药业有限公司 |
用作δ阿片类受体调节剂的嘧啶化合物
|
|
BR112012012905A2
(pt)
|
2009-12-04 |
2017-03-01 |
Hoffmann La Roche |
derivados de difenil azepina como inibidores da reabsorção de monoamina
|
|
US8664214B2
(en)
|
2010-03-30 |
2014-03-04 |
AbbVie Deutschland GmbH & Co. KG |
Small molecule potentiators of metabotropic glutamate receptors I
|
|
US8507535B2
(en)
*
|
2010-07-07 |
2013-08-13 |
Hoffmann-La Roche Inc. |
Methyl-pyrrolidine ether derivatives
|
|
WO2012075232A1
(en)
|
2010-12-04 |
2012-06-07 |
Trevena, Inc. |
Opioid receptor ligands and methods of using and making the same
|
|
EP3502236B1
(en)
|
2011-02-18 |
2023-08-23 |
The Scripps Research Institute |
Directed differentiation of oligodendrocyte precursor cells to a myelinating cell fate
|
|
SI2688403T1
(sl)
|
2011-03-23 |
2017-08-31 |
Trevena, Inc. |
Ligandi opioidnih receptorjev in metode uporabe in izdelave istega
|
|
US9464065B2
(en)
|
2011-03-24 |
2016-10-11 |
The Scripps Research Institute |
Compounds and methods for inducing chondrogenesis
|
|
JP2014159375A
(ja)
|
2011-06-15 |
2014-09-04 |
Takeda Chem Ind Ltd |
アゼパン化合物
|
|
US9630929B2
(en)
|
2011-10-31 |
2017-04-25 |
Xenon Pharmaceuticals Inc. |
Benzenesulfonamide compounds and their use as therapeutic agents
|
|
WO2013182612A1
(en)
|
2012-06-07 |
2013-12-12 |
Bayer Pharma Aktiengesellschaft |
Glucose transport inhibitors
|
|
EP2882739B1
(en)
|
2012-08-10 |
2017-05-03 |
Janssen Sciences Ireland UC |
New antibacterial compounds
|
|
BR112015022758A2
(pt)
|
2013-03-15 |
2017-07-18 |
Abbvie Deutschland |
derivados de pirrolidina, composições farmacêuticas contendo os mesmos e seu uso em terapia
|
|
EP3183232B1
(en)
|
2014-08-22 |
2023-05-03 |
The Arizona Board of Regents on behalf of The University of Arizona |
Substituted 1-arylethyl-4-acylaminopiperidine derivatives as opioid/alpha-adrenoreceptor modulators and method of their preparation
|
|
WO2016210403A1
(en)
|
2015-06-26 |
2016-12-29 |
The Regents Of The University Of Michigan |
G protein-coupled receptor kinase inhibitors and methods for use of the same
|
|
RS63319B1
(sr)
|
2015-09-02 |
2022-07-29 |
Trevena Inc |
Jedinjenja koja modulišu delta-opioidni receptor, koja sadrže 6-člani aza-heterociklik, postupci njihove upotrebe i spravljanja
|
|
AU2018221148B2
(en)
|
2017-02-17 |
2022-05-05 |
Trevena, Inc. |
5-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same
|
|
CN110446495B
(zh)
|
2017-02-17 |
2023-09-05 |
特维娜有限公司 |
含有7元氮杂杂环的δ阿片受体调节化合物及其使用和制备方法
|