|
US5783593A
(en)
*
|
1993-11-04 |
1998-07-21 |
Abbott Laboratories |
Inhibitors of squalene synthetase and protein farnesyltransferase
|
|
US6417185B1
(en)
|
1998-06-19 |
2002-07-09 |
Chiron Corporation |
Inhibitors of glycogen synthase kinase 3
|
|
BR0010651A
(pt)
*
|
1999-05-17 |
2002-03-19 |
Novo Nordisk As |
Composto, uso de um composto, composição farmacêutica, e, método para o tratamento e/ou prevenção de distúrbios ou de doenças mediadas por uma ação antagonìstica de glucagon
|
|
DE19929787A1
(de)
|
1999-06-29 |
2001-01-04 |
Bayer Ag |
Neue 4-(2-Oxodihydrooxadiazinylphenyl)amide und ihre Verwendung
|
|
DE10060807A1
(de)
*
|
2000-12-07 |
2002-06-20 |
Aventis Pharma Gmbh |
Ortho, ortho-substituierte stickstoffhaltige Bisarylverbindungen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
|
|
US7199147B2
(en)
|
2001-06-12 |
2007-04-03 |
Dainippon Sumitomo Pharma Co., Ltd. |
Rho kinase inhibitors
|
|
MXPA04002404A
(es)
*
|
2001-09-14 |
2004-05-31 |
Novo Nordisk As |
Ligandos novedosos para los sitios hisb10zn2+ del hexamero de insulina en estado r.
|
|
GB0124936D0
(en)
|
2001-10-17 |
2001-12-05 |
Glaxo Group Ltd |
Chemical compounds
|
|
US7119120B2
(en)
|
2001-12-26 |
2006-10-10 |
Genzyme Corporation |
Phosphate transport inhibitors
|
|
RS53118B
(sr)
*
|
2003-02-26 |
2014-06-30 |
Sugen Inc. |
Aminoheteroaril jedinjenja kao inhibitori protein kinaze
|
|
PT1603917E
(pt)
|
2003-03-14 |
2011-02-04 |
Medigene Ag |
Compostos heterocíclicos imunomoduladores
|
|
US20060160794A1
(en)
*
|
2003-06-12 |
2006-07-20 |
Amegadzie Albert K |
Tachykinin receptor antagonists
|
|
JP5017103B2
(ja)
|
2004-06-17 |
2012-09-05 |
トランスフオーム・フアーマシユーチカルズ・インコーポレーテツド |
薬剤共結晶組成物および関連した使用方法
|
|
CA2588517A1
(en)
|
2004-12-01 |
2006-06-08 |
Devgen N.V. |
5-carboxamido substituted thiazole derivatives that interact with ion channels, in particular with ion channels from the kv family
|
|
KR20070092297A
(ko)
*
|
2004-12-21 |
2007-09-12 |
데브젠 엔브이 |
Ｋｖ4 이온 채널 활성을 갖는 화합물
|
|
US8148535B2
(en)
*
|
2005-10-21 |
2012-04-03 |
Merck Sharp & Dohme Corp. |
Potassium channel inhibitors
|
|
DE102006005861A1
(de)
|
2006-02-09 |
2007-08-23 |
Aicuris Gmbh & Co. Kg |
Substituierte Chinolone III
|
|
EP1987004A2
(en)
|
2006-02-16 |
2008-11-05 |
Boehringer Ingelheim International GmbH |
Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors
|
|
US7601716B2
(en)
|
2006-05-01 |
2009-10-13 |
Cephalon, Inc. |
Pyridopyrazines and derivatives thereof as ALK and c-Met inhibitors
|
|
CA2651871A1
(en)
*
|
2006-05-10 |
2007-11-22 |
Renovis, Inc. |
Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
|
|
WO2007138110A2
(en)
|
2006-06-01 |
2007-12-06 |
Devgen N.V. |
Compounds that interact with ion channels, in particular with ion channels from the kv family
|
|
WO2007138112A2
(en)
|
2006-06-01 |
2007-12-06 |
Devgen N.V. |
Compounds that interact with ion channels, in particular with ion channels from the kv family
|
|
CA2666539A1
(en)
|
2006-10-23 |
2008-05-02 |
Pfizer Inc. |
Substituted phenylmethyl bicyclocarboxyamide compounds
|
|
US7956216B2
(en)
*
|
2006-12-21 |
2011-06-07 |
The Walter And Eliza Hall Institute Of Medical Research |
Alpha-helical mimetics
|
|
ATE461177T1
(de)
|
2007-03-23 |
2010-04-15 |
Icagen Inc |
Ionenkanal-hemmer
|
|
WO2009017838A2
(en)
|
2007-08-01 |
2009-02-05 |
Exelixis, Inc. |
Combinations of jak-2 inhibitors and other agents
|
|
EP2020413A1
(de)
|
2007-08-02 |
2009-02-04 |
Bayer CropScience AG |
Oxaspirocyclische-spiro-substituierte Tetram- und Tetronsäure-Derivate
|
|
ES2400604T3
(es)
|
2007-08-17 |
2013-04-11 |
Icagen, Inc. |
Heterociclos como moduladores del canal de potasio
|
|
DE102007044277A1
(de)
*
|
2007-09-17 |
2009-03-19 |
Grünenthal GmbH |
Substituierte Nicotinamid-Verbindungen und deren Verwendung in Arzneimitteln
|
|
EP2215054B8
(en)
*
|
2007-11-13 |
2012-02-08 |
Evotec AG |
Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
|
|
WO2009117421A2
(en)
*
|
2008-03-17 |
2009-09-24 |
Kalypsys, Inc. |
Heterocyclic modulators of gpr119 for treatment of disease
|
|
CL2009000916A1
(es)
|
2008-04-17 |
2010-12-31 |
Glaxo Group Ltd |
Compuestos derivados de 2-trifluorometil-1h-indol-5-metilcarboxamida, moduladores del receptor nicotinico de acetilcolina alfa7 (nachr); composicon farmaceutica; y uso para el tratamiento del deterioro cognitivo y de un trastorno psicotico como esquizofrenia.
|
|
TW201000447A
(en)
|
2008-05-30 |
2010-01-01 |
Astrazeneca Ab |
New compounds useful in pain therapy
|
|
TW201000446A
(en)
|
2008-05-30 |
2010-01-01 |
Astrazeneca Ab |
New compounds useful in pain therapy
|
|
PE20140572A1
(es)
|
2008-06-05 |
2014-05-16 |
Janssen Pharmaceutica Nv |
Combinaciones de drogas que comprenden un inhibidor de dgat y un agonista de ppar
|
|
JP2012519682A
(ja)
|
2009-03-03 |
2012-08-30 |
ファイザー・インク |
ガンマ−セクレターゼモジュレーターとしての新規フェニルイミダゾールおよびフェニルトリアゾール
|
|
TWI461197B
(zh)
*
|
2009-03-12 |
2014-11-21 |
|
2-mercaptoquinoline-3-carboxamide as a KCNQ2 / 3 modifier
|
|
TWI475020B
(zh)
|
2009-03-12 |
2015-03-01 |
|
The substituted nicotine amide as a KCNQ2 / 3 modifier
|
|
WO2011021645A1
(ja)
|
2009-08-19 |
2011-02-24 |
大日本住友製薬株式会社 |
２環性ウレア誘導体、またはその薬学的に許容される塩
|
|
JP2013028538A
(ja)
|
2009-11-13 |
2013-02-07 |
Dainippon Sumitomo Pharma Co Ltd |
新規アミド誘導体
|
|
KR101458006B1
(ko)
|
2010-10-18 |
2014-11-04 |
라퀄리아 파마 인코포레이티드 |
Ttx-s 차단제로서의 아릴아미드 유도체
|
|
DE102011101446A1
(de)
|
2011-05-10 |
2012-11-15 |
Aicuris Gmbh & Co. Kg |
Herstellung von "Dense Bodies" (DB)
|
|
EP2713722B1
(en)
|
2011-05-31 |
2017-03-15 |
Receptos, LLC |
Novel glp-1 receptor stabilizers and modulators
|
|
KR101476379B1
(ko)
*
|
2011-11-30 |
2014-12-29 |
한국과학기술연구원 |
페녹시프로판올 유도체 및 이를 함유하는 약학적 조성물
|
|
US10214476B2
(en)
|
2011-12-30 |
2019-02-26 |
Ecole Nationale Superieure De Chimie De Clermont Ferrand |
Pain relief compounds
|
|
MX2014012491A
(es)
*
|
2012-04-18 |
2014-11-14 |
Grünenthal GmbH |
4-aminobenzamidas sustituidas como moduladores de kcnq2/3.
|
|
AR094929A1
(es)
|
2013-02-28 |
2015-09-09 |
Bristol Myers Squibb Co |
Derivados de fenilpirazol como inhibidores potentes de rock1 y rock2
|
|
JPWO2015012328A1
(ja)
|
2013-07-24 |
2017-03-02 |
武田薬品工業株式会社 |
複素環化合物
|
|
JP2017114765A
(ja)
|
2014-04-25 |
2017-06-29 |
大正製薬株式会社 |
トリアゾリルで置換されたヘテロアリール化合物
|
|
JP6195684B2
(ja)
|
2014-06-03 |
2017-09-13 |
アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ |
ピラゾール化合物及びｔ型カルシウムチャンネルブロッカーとしてのそれらの使用
|
|
JP6619758B2
(ja)
|
2014-07-03 |
2019-12-11 |
ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム |
疾患を処置するためのｇｌｓ１阻害薬
|