JP2020506727A5 - - Google Patents
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- JP2020506727A5 JP2020506727A5 JP2019563679A JP2019563679A JP2020506727A5 JP 2020506727 A5 JP2020506727 A5 JP 2020506727A5 JP 2019563679 A JP2019563679 A JP 2019563679A JP 2019563679 A JP2019563679 A JP 2019563679A JP 2020506727 A5 JP2020506727 A5 JP 2020506727A5
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- Prior art keywords
- cancer
- chimeric protein
- receptor
- mutations
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022165861A JP7605800B2 (ja) | 2017-02-06 | 2022-10-14 | 標的化キメラタンパク質及びその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762454993P | 2017-02-06 | 2017-02-06 | |
| US62/454,993 | 2017-02-06 | ||
| PCT/EP2018/052814 WO2018141964A1 (en) | 2017-02-06 | 2018-02-05 | Targeted chimeric proteins and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022165861A Division JP7605800B2 (ja) | 2017-02-06 | 2022-10-14 | 標的化キメラタンパク質及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020506727A JP2020506727A (ja) | 2020-03-05 |
| JP2020506727A5 true JP2020506727A5 (enExample) | 2021-03-18 |
| JP7476467B2 JP7476467B2 (ja) | 2024-05-01 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019563679A Active JP7476467B2 (ja) | 2017-02-06 | 2018-02-05 | 標的化キメラタンパク質及びその使用 |
| JP2022165861A Active JP7605800B2 (ja) | 2017-02-06 | 2022-10-14 | 標的化キメラタンパク質及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022165861A Active JP7605800B2 (ja) | 2017-02-06 | 2022-10-14 | 標的化キメラタンパク質及びその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11384154B2 (enExample) |
| EP (1) | EP3577133A1 (enExample) |
| JP (2) | JP7476467B2 (enExample) |
| KR (1) | KR102642385B1 (enExample) |
| CN (1) | CN110546160A (enExample) |
| AU (1) | AU2018216032B2 (enExample) |
| CA (1) | CA3052523A1 (enExample) |
| IL (1) | IL268346B2 (enExample) |
| MX (1) | MX2019009255A (enExample) |
| WO (1) | WO2018141964A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109563141A (zh) * | 2016-05-13 | 2019-04-02 | 奥里尼斯生物科学公司 | 对非细胞结构的治疗性靶向 |
| EP3577133A1 (en) * | 2017-02-06 | 2019-12-11 | Orionis Biosciences NV | Targeted chimeric proteins and uses thereof |
| CN117924493A (zh) | 2017-08-09 | 2024-04-26 | 奥里尼斯生物科学有限公司 | Clec9a结合剂及其用途 |
| JP7347899B2 (ja) | 2017-08-09 | 2023-09-20 | オリオンズ バイオサイエンス インコーポレイテッド | Ｃｄ８結合物質 |
| CN119285770A (zh) | 2017-08-09 | 2025-01-10 | 奥里尼斯生物科学有限公司 | Pd-1和pd-l1结合剂 |
| MX2020008208A (es) | 2018-02-05 | 2020-11-09 | Orionis Biosciences Inc | Agentes de unión a fibroblastos y uso de estos. |
| US12084497B2 (en) | 2018-08-08 | 2024-09-10 | Orionis Biosciences, Inc. | SIRP1α targeted chimeric proteins and uses thereof |
| BR112021005465A2 (pt) * | 2018-10-02 | 2021-06-15 | Mitsubishi Tanabe Pharma Corporation | agentes de ligação biespecíficos direcionados ao sindecano-1 e receptor do fator de crescimento de fibroblasto |
| AU2019370031A1 (en) * | 2018-10-29 | 2021-05-27 | Umc Utrecht Holding B.V. | IgA mediated killing of aberrant cells by CD47- SIRPα checkpoint inhibition of neutrophils |
| US12410225B2 (en) | 2018-11-08 | 2025-09-09 | Orionis Biosciences, Inc | Modulation of dendritic cell lineages |
| WO2020102422A1 (en) | 2018-11-14 | 2020-05-22 | Arch Oncology, Inc. | THERAPEUTIC SIRPα ANTIBODIES |
| JP7689079B2 (ja) | 2019-03-28 | 2025-06-05 | オリオニス バイオサイエンシズ，インコーポレイテッド | 治療用インターフェロンアルファ１タンパク質 |
| US12351614B2 (en) | 2019-03-28 | 2025-07-08 | Orionis Biosciences, Inc. | CLEC9A-based chimeric protein complexes |
| EP4023679A4 (en) * | 2019-08-30 | 2023-10-04 | Nanjing Shunxin Pharmaceuticals Co., Ltd. of Chiatai Tianqing Pharmaceutical Group | FUSION PROTEIN TARGETING PD-L1 AND TGF-BETA AND USE THEREOF |
| EP4034146A4 (en) * | 2019-09-26 | 2024-03-06 | Orionis Biosciences, Inc. | CONJUGATED CHIMERIC PROTEINS |
| EP4061951A4 (en) * | 2019-11-18 | 2024-03-13 | The Brigham & Women's Hospital, Inc. | NEXT GENERATION CODON-OPTIMIZED ONCOLYTIC ONCOLYTIC HERPES SIMPLEX VIRUS TYPE 1 AND METHODS OF USE |
| AU2020398327A1 (en) | 2019-12-03 | 2022-07-14 | Evotec International Gmbh | Interferon-associated antigen binding proteins and uses thereof |
| CN113354738B (zh) * | 2020-03-05 | 2022-09-09 | 绍兴德方华生物技术有限公司 | 融合毒素VEGF165b/mGEL及其编码基因与应用 |
| US20230279108A1 (en) * | 2020-04-30 | 2023-09-07 | Arch Oncology, Inc. | Therapeutic sirp-alpha antibodies |
| CN115698076A (zh) * | 2020-06-30 | 2023-02-03 | 正大天晴药业集团股份有限公司 | 用于治疗肿瘤的药物 |
| AU2021331474A1 (en) * | 2020-08-27 | 2023-03-16 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Oncolytic viruses encoding recombinant transforming growth factor (tgf)-beta monomers and uses thereof |
| WO2022053651A2 (en) | 2020-09-10 | 2022-03-17 | Precirix N.V. | Antibody fragment against fap |
| US20220196651A1 (en) * | 2020-12-06 | 2022-06-23 | ALX Oncology Inc. | Multimers for reducing the interference of drugs that bind cd47 in serological assays |
| CN114349850A (zh) * | 2020-12-18 | 2022-04-15 | 蒋庆华 | 抗体及其制备方法和编码核酸以及工程细胞 |
| WO2023203135A1 (en) | 2022-04-22 | 2023-10-26 | Precirix N.V. | Improved radiolabelled antibody |
| IL318992A (en) | 2022-05-02 | 2025-04-01 | Precirix N V | Cancer treatment through advance directives |
| JP2025537826A (ja) | 2022-11-16 | 2025-11-20 | ベーリンガー・インゲルハイム・インターナショナル・ゲーエムベーハー | 抗ｓｉｒｐａ抗体についての効力予測バイオマーカー |
| EP4480501A1 (en) * | 2023-06-21 | 2024-12-25 | Nmi Naturwissenschaftliches Und Medizinisches Institut An Der Universität Tübingen | Sirp nanobodies |
| WO2025026282A1 (en) * | 2023-07-29 | 2025-02-06 | Shanghai Kaijin Biotechnology, Ltd | Modified type e multi-specific antibodies |
| CN117430716B (zh) * | 2023-10-16 | 2024-05-31 | 珠海臻谱基因科技有限公司 | 靶向保守的HIV gp41亚基近膜端外区的重组干扰素药物及其应用 |
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- 2018-02-05 CN CN201880023712.1A patent/CN110546160A/zh active Pending
- 2018-02-05 CA CA3052523A patent/CA3052523A1/en active Pending
- 2018-02-05 JP JP2019563679A patent/JP7476467B2/ja active Active
- 2018-02-05 WO PCT/EP2018/052814 patent/WO2018141964A1/en not_active Ceased
- 2018-02-05 US US16/483,114 patent/US11384154B2/en active Active
- 2018-02-05 MX MX2019009255A patent/MX2019009255A/es unknown
- 2018-02-05 KR KR1020197024342A patent/KR102642385B1/ko active Active
- 2018-02-05 AU AU2018216032A patent/AU2018216032B2/en active Active
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2022
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- 2022-10-14 JP JP2022165861A patent/JP7605800B2/ja active Active
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