JP2020530298A5 - - Google Patents
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- JP2020530298A5 JP2020530298A5 JP2020507585A JP2020507585A JP2020530298A5 JP 2020530298 A5 JP2020530298 A5 JP 2020530298A5 JP 2020507585 A JP2020507585 A JP 2020507585A JP 2020507585 A JP2020507585 A JP 2020507585A JP 2020530298 A5 JP2020530298 A5 JP 2020530298A5
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- cancer
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- QNRATNLHPGXHMA-XZHTYLCXSA-N (r)-(6-ethoxyquinolin-4-yl)-[(2s,4s,5r)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]methanol;hydrochloride Chemical compound Cl.C([C@H]([C@H](C1)CC)C2)CN1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OCC)C=C21 QNRATNLHPGXHMA-XZHTYLCXSA-N 0.000 claims 1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762542921P | 2017-08-09 | 2017-08-09 | |
| US62/542,921 | 2017-08-09 | ||
| PCT/US2018/045743 WO2019032663A1 (en) | 2017-08-09 | 2018-08-08 | PD-1 AND PD-L1 BINDING AGENTS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020530298A JP2020530298A (ja) | 2020-10-22 |
| JP2020530298A5 true JP2020530298A5 (enExample) | 2021-09-16 |
| JP7423511B2 JP7423511B2 (ja) | 2024-01-29 |
Family
ID=65271869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020507585A Active JP7423511B2 (ja) | 2017-08-09 | 2018-08-08 | Ｐｄ－１およびｐｄ－ｌ１結合物質 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US11498966B2 (enExample) |
| EP (1) | EP3664829A4 (enExample) |
| JP (1) | JP7423511B2 (enExample) |
| CN (2) | CN111328286B (enExample) |
| CA (2) | CA3314464A1 (enExample) |
| WO (1) | WO2019032663A1 (enExample) |
Families Citing this family (37)
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| EP3455245A2 (en) * | 2016-05-13 | 2019-03-20 | Orionis Biosciences NV | Therapeutic targeting of non-cellular structures |
| BR112019018915A2 (pt) | 2017-03-15 | 2020-04-14 | Pandion Therapeutics Inc | imunotolerância direcionada |
| AU2018273914A1 (en) | 2017-05-24 | 2019-11-14 | Pandion Operations, Inc. | Targeted immunotolerance |
| US10946068B2 (en) | 2017-12-06 | 2021-03-16 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| US10174091B1 (en) | 2017-12-06 | 2019-01-08 | Pandion Therapeutics, Inc. | IL-2 muteins |
| USRE50550E1 (en) | 2017-12-06 | 2025-08-26 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
| US12655186B2 (en) | 2018-01-26 | 2026-06-16 | Orionis Biosciences, Inc. | Chimeric protein comprising anti-XCR1 antibody and modified interferon alpha 2 |
| CA3090406A1 (en) | 2018-02-05 | 2019-08-08 | Orionis Biosciences, Inc. | Fibroblast binding agents and use thereof |
| GB2593632B8 (en) * | 2018-10-29 | 2026-07-08 | Umc Utrecht Holding Bv | IGA mediated killing of aberrant cells by CD47-Sirpalpha checkpoint inhibition of neutrophils |
| EP3890773A4 (en) | 2018-11-08 | 2022-11-09 | Orionis Biosciences, Inc. | MODULATION OF DENDRITIC CELL LINES |
| WO2020198665A1 (en) | 2019-03-28 | 2020-10-01 | Orionis Biosciences, Inc. | Fibroblast activation protein binding agents and use thereof |
| CN113840833B (zh) | 2019-03-28 | 2025-06-17 | 奥里尼斯生物科学股份有限公司 | 基于clec9a的嵌合蛋白复合物 |
| JP7689079B2 (ja) | 2019-03-28 | 2025-06-05 | オリオニス バイオサイエンシズ，インコーポレイテッド | 治療用インターフェロンアルファ１タンパク質 |
| CA3136453A1 (en) * | 2019-04-18 | 2020-10-22 | Qlsf Biotherapeutics Inc. | Humanized anti-pd-l1 antibodies |
| AU2020279240A1 (en) | 2019-05-20 | 2021-12-23 | Pandion Operations, Inc. | MAdCAM targeted immunotolerance |
| CN116987191A (zh) * | 2019-06-27 | 2023-11-03 | 启愈生物技术(上海)有限公司 | 抗PD-L1纳米抗体及其Fc融合蛋白和应用 |
| EP4034146A4 (en) * | 2019-09-26 | 2024-03-06 | Orionis Biosciences, Inc. | CONJUGATED CHIMERIC PROTEINS |
| CN114761430A (zh) * | 2019-09-26 | 2022-07-15 | 奥里尼斯生物科学股份有限公司 | 靶向pd-l1的嵌合蛋白及其用途 |
| EP4059962A4 (en) * | 2019-10-30 | 2023-11-29 | Sanyou Biopharmaceuticals Co., Ltd. | Pd-l1 binding molecule |
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| BR112023016706A2 (pt) * | 2021-02-19 | 2023-10-31 | Seoul Nat Univ R&Db Foundation | Anticorpo ou um fragmento de ligação ao antígeno do mesmo, molécula de ácido nucleico, métodos para produzir um anticorpo ou um fragmento de ligação ao antígeno do mesmo e para detectar agrupamento de diferenciação 47 ou determinar uma quantidade de agrupamento de diferenciação 47 em uma amostra, e, uso do anticorpo ou de um fragmento de ligação ao antígeno do mesmo |
| TWI833227B (zh) * | 2021-05-28 | 2024-02-21 | 大陸商和鉑醫藥（上海）有限責任公司 | 靶向pd-l1和cd73的特異性結合蛋白及其應用 |
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| WO2023203135A1 (en) | 2022-04-22 | 2023-10-26 | Precirix N.V. | Improved radiolabelled antibody |
| AU2023264245A1 (en) | 2022-05-02 | 2024-12-19 | Precirix N.V. | Pre-targeting |
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| JP2026517051A (ja) * | 2023-01-18 | 2026-05-28 | エルピサイエンス・（スージョウ）・バイオファーマ，リミテッド | 抗ｐｄｌ１単一ドメイン抗体、融合タンパク質及びその使用 |
| TW202608919A (zh) | 2024-04-12 | 2026-03-01 | 美商派拉岡醫療公司 | 白蛋白結合蛋白及使用方法 |
| TW202547857A (zh) * | 2024-04-12 | 2025-12-16 | 美商派拉岡醫療公司 | 抗ｈａｓ抗體及其組合物 |
| WO2026015864A1 (en) * | 2024-07-12 | 2026-01-15 | Outpace Bio, Inc. | Cd8 binding polypeptides and methods of use |
| KR20260116273A (ko) | 2024-09-20 | 2026-07-28 | 파라곤 테라퓨틱스, 인크. | Pd-1 결합 단백질, vegf 및 pd-1 이중특이적 결합 단백질, 조성물 및 사용 방법 |
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