JP2020504082A - 血液凝固障害の処置又は予防における血管外投与のための切断型フォン・ヴィルブランド因子ポリペプチド - Google Patents

血液凝固障害の処置又は予防における血管外投与のための切断型フォン・ヴィルブランド因子ポリペプチド Download PDF

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JP2020504082A
JP2020504082A JP2019524345A JP2019524345A JP2020504082A JP 2020504082 A JP2020504082 A JP 2020504082A JP 2019524345 A JP2019524345 A JP 2019524345A JP 2019524345 A JP2019524345 A JP 2019524345A JP 2020504082 A JP2020504082 A JP 2020504082A
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fviii
recombinant polypeptide
administered
polypeptide
vwf
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JP2020504082A5 (enExample
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ザビーネ・ペステル
エルマー・ラクエット
トーマス・ヴァイマー
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ツェー・エス・エル・ベーリング・レングナウ・アクチエンゲゼルシャフト
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2019524345A 2016-11-11 2017-11-10 血液凝固障害の処置又は予防における血管外投与のための切断型フォン・ヴィルブランド因子ポリペプチド Pending JP2020504082A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16198497.6 2016-11-11
EP16198497 2016-11-11
PCT/EP2017/078840 WO2018087271A1 (en) 2016-11-11 2017-11-10 Truncated von willebrand factor polypeptides for extravascular administration in the treatment or prophylaxis of a blood coagulation disorder

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JP2020504082A true JP2020504082A (ja) 2020-02-06
JP2020504082A5 JP2020504082A5 (enExample) 2020-12-10

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US (1) US11890327B2 (enExample)
EP (1) EP3538134B1 (enExample)
JP (1) JP2020504082A (enExample)
KR (1) KR20190073576A (enExample)
CN (1) CN110381986B (enExample)
AU (1) AU2017358865A1 (enExample)
CA (1) CA3043397A1 (enExample)
DK (1) DK3538134T3 (enExample)
ES (1) ES2908008T3 (enExample)
SG (2) SG10201912768YA (enExample)
TW (1) TW201828974A (enExample)
WO (1) WO2018087271A1 (enExample)

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KR20220029733A (ko) 2019-07-04 2022-03-08 체에스엘 베링 렝나우 아게 응고 인자 viii의 시험관내 안정성을 증가시키기 위한 절단된 폰 빌레브란트 인자 (vwf)
EP4058049A1 (en) 2019-11-11 2022-09-21 CSL Behring Lengnau AG Polypeptides for inducing tolerance to factor viii
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EP3538134A1 (en) 2019-09-18
US11890327B2 (en) 2024-02-06
EP3538134B1 (en) 2021-12-29
CA3043397A1 (en) 2018-05-17
ES2908008T3 (es) 2022-04-27
AU2017358865A1 (en) 2019-05-09
WO2018087271A1 (en) 2018-05-17
CN110381986A (zh) 2019-10-25
SG11201903954WA (en) 2019-05-30
SG10201912768YA (en) 2020-02-27
DK3538134T3 (da) 2022-02-07
US20210268071A1 (en) 2021-09-02
KR20190073576A (ko) 2019-06-26
TW201828974A (zh) 2018-08-16
CN110381986B (zh) 2023-08-18

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