AU2017358865A1 - Truncated von willebrand factor polypeptides for extravascular administration in the treatment or prophylaxis of a blood coagulation disorder - Google Patents

Truncated von willebrand factor polypeptides for extravascular administration in the treatment or prophylaxis of a blood coagulation disorder Download PDF

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Publication number
AU2017358865A1
AU2017358865A1 AU2017358865A AU2017358865A AU2017358865A1 AU 2017358865 A1 AU2017358865 A1 AU 2017358865A1 AU 2017358865 A AU2017358865 A AU 2017358865A AU 2017358865 A AU2017358865 A AU 2017358865A AU 2017358865 A1 AU2017358865 A1 AU 2017358865A1
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AU
Australia
Prior art keywords
fviii
recombinant polypeptide
administered
polypeptide
vwf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2017358865A
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English (en)
Inventor
Sabine Pestel
Elmar RAQUET
Thomas Weimer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CSL Behring Lengnau AG
Original Assignee
CSL Behring Lengnau AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CSL Behring Lengnau AG filed Critical CSL Behring Lengnau AG
Publication of AU2017358865A1 publication Critical patent/AU2017358865A1/en
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • A61K38/37Factors VIII
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU2017358865A 2016-11-11 2017-11-10 Truncated von willebrand factor polypeptides for extravascular administration in the treatment or prophylaxis of a blood coagulation disorder Abandoned AU2017358865A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16198497 2016-11-11
EP16198497.6 2016-11-11
PCT/EP2017/078840 WO2018087271A1 (en) 2016-11-11 2017-11-10 Truncated von willebrand factor polypeptides for extravascular administration in the treatment or prophylaxis of a blood coagulation disorder

Publications (1)

Publication Number Publication Date
AU2017358865A1 true AU2017358865A1 (en) 2019-05-09

Family

ID=57389201

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017358865A Abandoned AU2017358865A1 (en) 2016-11-11 2017-11-10 Truncated von willebrand factor polypeptides for extravascular administration in the treatment or prophylaxis of a blood coagulation disorder

Country Status (12)

Country Link
US (1) US11890327B2 (enExample)
EP (1) EP3538134B1 (enExample)
JP (1) JP2020504082A (enExample)
KR (1) KR20190073576A (enExample)
CN (1) CN110381986B (enExample)
AU (1) AU2017358865A1 (enExample)
CA (1) CA3043397A1 (enExample)
DK (1) DK3538134T3 (enExample)
ES (1) ES2908008T3 (enExample)
SG (2) SG11201903954WA (enExample)
TW (1) TW201828974A (enExample)
WO (1) WO2018087271A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
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AU2020300820A1 (en) * 2019-07-04 2022-03-03 CSL Behring Lengnau AG A truncated von willebrand factor (vWF) for increasing the in vitro stability of coagulation factor VIII
WO2021094344A1 (en) 2019-11-11 2021-05-20 CSL Behring Lengnau AG Polypeptides for inducing tolerance to factor viii
KR102647642B1 (ko) * 2021-05-04 2024-03-15 (주)케어젠 혈액 응고 활성을 갖는 펩타이드와 이의 용도

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RU2017145002A (ru) 2015-05-22 2019-06-24 Цсл Беринг Ленгнау Аг Способы получения модифицированного фактора фон виллебранда

Also Published As

Publication number Publication date
EP3538134B1 (en) 2021-12-29
CN110381986B (zh) 2023-08-18
WO2018087271A1 (en) 2018-05-17
ES2908008T3 (es) 2022-04-27
US11890327B2 (en) 2024-02-06
CA3043397A1 (en) 2018-05-17
SG11201903954WA (en) 2019-05-30
DK3538134T3 (da) 2022-02-07
TW201828974A (zh) 2018-08-16
US20210268071A1 (en) 2021-09-02
CN110381986A (zh) 2019-10-25
SG10201912768YA (en) 2020-02-27
EP3538134A1 (en) 2019-09-18
JP2020504082A (ja) 2020-02-06
KR20190073576A (ko) 2019-06-26

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MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application