JP2020503364A5 - - Google Patents
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- JP2020503364A5 JP2020503364A5 JP2019537099A JP2019537099A JP2020503364A5 JP 2020503364 A5 JP2020503364 A5 JP 2020503364A5 JP 2019537099 A JP2019537099 A JP 2019537099A JP 2019537099 A JP2019537099 A JP 2019537099A JP 2020503364 A5 JP2020503364 A5 JP 2020503364A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- item
- dose
- tim
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022062862A JP7472190B2 (ja) | 2017-01-09 | 2022-04-05 | 抗ｔｉｍ－３抗体を用いてがんを処置する方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762444354P | 2017-01-09 | 2017-01-09 | |
| US62/444,354 | 2017-01-09 | ||
| US201762582272P | 2017-11-06 | 2017-11-06 | |
| US62/582,272 | 2017-11-06 | ||
| PCT/US2018/013021 WO2018129553A1 (en) | 2017-01-09 | 2018-01-09 | Methods of treating cancer with anti-tim-3 antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022062862A Division JP7472190B2 (ja) | 2017-01-09 | 2022-04-05 | 抗ｔｉｍ－３抗体を用いてがんを処置する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020503364A JP2020503364A (ja) | 2020-01-30 |
| JP2020503364A5 true JP2020503364A5 (enExample) | 2021-02-18 |
| JP7118073B2 JP7118073B2 (ja) | 2022-08-15 |
Family
ID=61163782
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019537099A Active JP7118073B2 (ja) | 2017-01-09 | 2018-01-09 | 抗ｔｉｍ－３抗体を用いてがんを処置する方法 |
| JP2022062862A Active JP7472190B2 (ja) | 2017-01-09 | 2022-04-05 | 抗ｔｉｍ－３抗体を用いてがんを処置する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022062862A Active JP7472190B2 (ja) | 2017-01-09 | 2022-04-05 | 抗ｔｉｍ－３抗体を用いてがんを処置する方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11926665B2 (enExample) |
| EP (1) | EP3565594A1 (enExample) |
| JP (2) | JP7118073B2 (enExample) |
| KR (1) | KR102671283B1 (enExample) |
| CN (1) | CN110382000A (enExample) |
| AU (1) | AU2018205401B2 (enExample) |
| BR (1) | BR112019014169A2 (enExample) |
| CA (1) | CA3049536A1 (enExample) |
| IL (1) | IL267803A (enExample) |
| MA (1) | MA47206A (enExample) |
| MX (1) | MX2019008208A (enExample) |
| SG (1) | SG10201913083SA (enExample) |
| TW (2) | TWI841209B (enExample) |
| WO (1) | WO2018129553A1 (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE048111T2 (hu) | 2015-03-23 | 2020-05-28 | Bayer Pharma AG | Anti-CEACAM6 ellenanyagok és alkalmazásuk |
| EP3277321B1 (en) | 2015-04-01 | 2024-08-14 | AnaptysBio, Inc. | Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3) |
| KR102576042B1 (ko) | 2016-10-11 | 2023-09-07 | 아게누스 인코포레이티드 | 항-lag-3 항체 및 이의 사용 방법 |
| SG11201903867YA (en) * | 2016-11-01 | 2019-05-30 | Anaptysbio Inc | Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3) |
| EP3666794A1 (en) * | 2016-11-01 | 2020-06-17 | AnaptysBio, Inc. | Antibodies directed against programmed death- 1 (pd-1) |
| EP3565844B8 (en) | 2017-01-09 | 2023-04-12 | Tesaro, Inc. | Methods of treating cancer with anti-pd-1 antibodies |
| JP7118073B2 (ja) | 2017-01-09 | 2022-08-15 | テサロ， インコーポレイテッド | 抗ｔｉｍ－３抗体を用いてがんを処置する方法 |
| TW202444417A (zh) | 2017-05-09 | 2024-11-16 | 美商提薩羅有限公司 | 治療癌症的組合療法 |
| EP3624850A1 (en) | 2017-05-18 | 2020-03-25 | Tesaro, Inc. | Combination therapies for treating cancer |
| AU2018341479B2 (en) | 2017-09-26 | 2022-02-17 | Tesaro, Inc. | Niraparib formulations |
| KR20200086664A (ko) | 2017-09-30 | 2020-07-17 | 테사로, 인코포레이티드 | 암을 치료하기 위한 조합 요법 |
| MA50618A (fr) | 2017-10-06 | 2020-08-12 | Tesaro Inc | Polyrhérapies et leurs utilisations |
| EP3740506A1 (en) * | 2018-01-16 | 2020-11-25 | Bristol-Myers Squibb Company | Methods of treating cancer with antibodies against tim3 |
| CN118994103A (zh) | 2018-10-03 | 2024-11-22 | 特沙诺有限公司 | 尼拉帕利盐 |
| US20210347758A1 (en) | 2018-10-03 | 2021-11-11 | Tesaro, Inc. | Crystalline Forms of Niraparib Freebase |
| JP2022505925A (ja) * | 2018-11-01 | 2022-01-14 | メルク パテント ゲーエムベーハー | 抗ｔｉｍ－３抗体 |
| EP3897844B1 (en) | 2018-12-19 | 2023-11-15 | Deutsches Krebsforschungszentrum | Pharmaceutical combination of anti ceacam6 and tim3 antibodies |
| CN113614109A (zh) | 2018-12-21 | 2021-11-05 | Ose免疫疗法公司 | 双功能抗pd-1/il-7分子 |
| US20220089740A1 (en) * | 2019-01-11 | 2022-03-24 | Eli Lilly And Company | Tim-3 antibodies and combinations with other checkpoint inhibitors for the treatment of cancer |
| WO2020165374A1 (en) | 2019-02-14 | 2020-08-20 | Ose Immunotherapeutics | Bifunctional molecule comprising il-15ra |
| AU2020406083A1 (en) | 2019-12-17 | 2022-06-16 | Boehringer Ingelheim International Gmbh | Bifunctional molecules comprising an IL-7 variant |
| US20230131598A1 (en) | 2020-04-14 | 2023-04-27 | Glaxosmithkline Intellectual Property Development Limited | Combination treatment for cancer |
| WO2021209357A1 (en) | 2020-04-14 | 2021-10-21 | Glaxosmithkline Intellectual Property Development Limited | Combination treatment for cancer involving anti-icos and anti-pd1 antibodies, optionally further involving anti-tim3 antibodies |
| WO2022006091A1 (en) * | 2020-06-29 | 2022-01-06 | Anovent Pharmaceutical (U.S.), Llc | Biopharmaceutical formulation of anti-pd-1, anti-pd-l1, and anti-vegfr therapeutic monoclonal antibodies and method for treating nsclc by inhalation |
| WO2022148781A1 (en) | 2021-01-05 | 2022-07-14 | Institut Curie | Combination of mcoln activators and immune checkpoint inhibitors |
| WO2022214653A1 (en) | 2021-04-09 | 2022-10-13 | Ose Immunotherapeutics | New scaffold for bifunctional molecules with improved properties |
| US20240182572A1 (en) | 2021-04-09 | 2024-06-06 | Ose Immunotherapeutics | Scaffold for bifunctional molecules comprising pd-1 or cd28 and sirp binding domains |
| WO2022221245A1 (en) * | 2021-04-13 | 2022-10-20 | Medimmune, Llc | Bispecific antibody targeting pd-1 and tim-3 |
| JP2024516616A (ja) | 2021-04-23 | 2024-04-16 | スゾウ ネオロジクス バイオサイエンス シーオー．， エルティーディー． | Ｔｉｍ－３を標的とする抗体及びその使用 |
| US11970548B2 (en) * | 2021-08-27 | 2024-04-30 | Innovative Cellular Therapeutics Holdings, Ltd. | Nanobody target GCC and uses in chimeric antigen receptor cell therapy |
| WO2023031366A1 (en) | 2021-09-02 | 2023-03-09 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Anti-cecam6 antibodies with reduced side-effects |
| US20230391873A1 (en) * | 2022-06-02 | 2023-12-07 | Memorial Sloan-Kettering Cancer Center | Methods for treating mismatch repair deficient locally advanced rectal cancer using dostarlimab |
| WO2024003360A1 (en) | 2022-07-01 | 2024-01-04 | Institut Curie | Biomarkers and uses thereof for the treatment of neuroblastoma |
| EP4565610A1 (en) | 2022-08-02 | 2025-06-11 | Ose Immunotherapeutics | Multifunctional molecule directed against cd28 |
| TW202440634A (zh) * | 2023-03-08 | 2024-10-16 | 美商英塞特公司 | 用於治療癌症之抗－ｐｄ－１活性劑、抗－ｔｉｍ－３活性劑及抗－ｌａｇ－３活性劑之組合療法 |
| JP2026512425A (ja) | 2023-03-30 | 2026-04-16 | オーエスイー・イミュノセラピューティクス | 免疫細胞増強分子の発現のための活性化免疫細胞に標的化された脂質ベースのナノ粒子及びその使用 |
| EP4687990A1 (en) | 2023-03-30 | 2026-02-11 | Ose Immunotherapeutics | Method of synthesis of targeted lipid nanoparticle and uses thereof |
| WO2025014933A1 (en) * | 2023-07-10 | 2025-01-16 | Northwestern University | Targeting tim-3 in mapk-driven glioma |
| WO2025242835A1 (en) | 2024-05-22 | 2025-11-27 | Ose Immunotherapeutics | Molecules comprising masking linkers and uses thereof for the treatment of cancer |
| WO2025242836A1 (en) | 2024-05-22 | 2025-11-27 | Ose Immunotherapeutics | Molecules comprising masking linkers and uses thereof for the treatment of auto-immune or inflammatory diseases and disorders |
| WO2026068705A1 (en) | 2024-09-26 | 2026-04-02 | Ose Immunotherapeutics | Lipid-based nanoparticles comprising non-glycosylated fc domains and uses thereof |
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| US4828981A (en) | 1983-08-24 | 1989-05-09 | Synbiotics Corporation | Immunoassays for determining Dirofilaria immitis infection using antiidiotype monoclonal antibody reagents |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| WO1992008796A1 (en) | 1990-11-13 | 1992-05-29 | Immunex Corporation | Bifunctional selectable fusion genes |
| AU6953394A (en) | 1993-05-21 | 1994-12-20 | Targeted Genetics Corporation | Bifunctional selectable fusion genes based on the cytosine deaminase (cd) gene |
| US5464758A (en) | 1993-06-14 | 1995-11-07 | Gossen; Manfred | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
| US5814618A (en) | 1993-06-14 | 1998-09-29 | Basf Aktiengesellschaft | Methods for regulating gene expression |
| WO2001057219A2 (en) | 2000-02-02 | 2001-08-09 | Schering Corporation | Mammalian interleukin-1-delta and -epsilon. their use in therapeutic and diagnostic methods |
| FR2814642B1 (fr) | 2000-10-03 | 2005-07-01 | Ass Pour Le Dev De La Rech En | Souris transgenique pour la recombinaison ciblee mediee par la cre-er modifiee |
| US20030103985A1 (en) | 2001-05-18 | 2003-06-05 | Boehringer Ingelheim International Gmbh | Cytotoxic CD44 antibody immunoconjugates |
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| JP4694128B2 (ja) | 2002-01-30 | 2011-06-08 | ザ ブライハム アンド ウイメンズ ホスピタル， インコーポレイテッド | ＴＩＭ−３、Ｔｈ１特異的細胞表面分子に関連した組成物および方法 |
| WO2003089609A2 (en) | 2002-04-17 | 2003-10-30 | Richard Metz | Short fragment homologous replacement to provide bse resistant cattle |
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| PL2161336T5 (pl) | 2005-05-09 | 2017-10-31 | Ono Pharmaceutical Co | Ludzkie przeciwciała monoklonalne przeciwko białku Programmed Death 1 (PD-1) oraz sposoby leczenia raka z zastosowaniem samych przeciwciał anty-PD-1 lub w połączeniu z innymi środkami immunoterapeutycznymi |
| US7824681B2 (en) | 2005-08-16 | 2010-11-02 | The United States Of America As Represented By The Department Of Health And Human Services | Human monoclonal antibodies that specifically bind IGF-II |
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| ES2763548T3 (es) | 2014-11-06 | 2020-05-29 | Hoffmann La Roche | Anticuerpos anti-TIM3 y procedimientos de uso |
| MA41463A (fr) | 2015-02-03 | 2017-12-12 | Anaptysbio Inc | Anticorps dirigés contre le gène d'activation 3 des lymphocytes (lag-3) |
| EP3277321B1 (en) | 2015-04-01 | 2024-08-14 | AnaptysBio, Inc. | Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3) |
| ES2878188T3 (es) | 2015-07-29 | 2021-11-18 | Novartis Ag | Terapias de combinación que comprenden moléculas de anticuerpos contra LAG-3 |
| KR20250099459A (ko) | 2015-11-03 | 2025-07-01 | 얀센 바이오테크 인코포레이티드 | Pd-1과 특이적으로 결합하는 항체 및 그의 용도 |
| AR108377A1 (es) | 2016-05-06 | 2018-08-15 | Medimmune Llc | Proteínas de unión biespecíficas y sus usos |
| FI3478286T3 (fi) | 2016-06-29 | 2024-03-14 | Tesaro Inc | Menetelmiä munasarjasyövän hoitamiseksi |
| IL264970B2 (en) | 2016-08-26 | 2024-12-01 | Beigene Ltd | ANTI–TIM–3 antibodies and their use |
| SG11201903867YA (en) | 2016-11-01 | 2019-05-30 | Anaptysbio Inc | Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3) |
| JP7118073B2 (ja) | 2017-01-09 | 2022-08-15 | テサロ， インコーポレイテッド | 抗ｔｉｍ－３抗体を用いてがんを処置する方法 |
| AR111651A1 (es) * | 2017-04-28 | 2019-08-07 | Novartis Ag | Conjugados de anticuerpos que comprenden agonistas del receptor de tipo toll y terapias de combinación |
-
2018
- 2018-01-09 JP JP2019537099A patent/JP7118073B2/ja active Active
- 2018-01-09 SG SG10201913083SA patent/SG10201913083SA/en unknown
- 2018-01-09 US US16/476,534 patent/US11926665B2/en active Active
- 2018-01-09 WO PCT/US2018/013021 patent/WO2018129553A1/en not_active Ceased
- 2018-01-09 KR KR1020197023158A patent/KR102671283B1/ko active Active
- 2018-01-09 TW TW112102836A patent/TWI841209B/zh active
- 2018-01-09 CN CN201880016126.4A patent/CN110382000A/zh active Pending
- 2018-01-09 MA MA047206A patent/MA47206A/fr unknown
- 2018-01-09 AU AU2018205401A patent/AU2018205401B2/en active Active
- 2018-01-09 EP EP18703388.1A patent/EP3565594A1/en active Pending
- 2018-01-09 CA CA3049536A patent/CA3049536A1/en active Pending
- 2018-01-09 MX MX2019008208A patent/MX2019008208A/es unknown
- 2018-01-09 BR BR112019014169-3A patent/BR112019014169A2/pt unknown
- 2018-01-09 TW TW107100821A patent/TWI793094B/zh active
-
2019
- 2019-07-02 IL IL267803A patent/IL267803A/en unknown
-
2022
- 2022-04-05 JP JP2022062862A patent/JP7472190B2/ja active Active
-
2024
- 2024-02-02 US US18/430,835 patent/US20240301057A1/en active Pending
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