SG10201913083SA - Methods of treating cancer with anti-tim-3 antibodies - Google Patents
Methods of treating cancer with anti-tim-3 antibodiesInfo
- Publication number
- SG10201913083SA SG10201913083SA SG10201913083SA SG10201913083SA SG10201913083SA SG 10201913083S A SG10201913083S A SG 10201913083SA SG 10201913083S A SG10201913083S A SG 10201913083SA SG 10201913083S A SG10201913083S A SG 10201913083SA SG 10201913083S A SG10201913083S A SG 10201913083SA
- Authority
- SG
- Singapore
- Prior art keywords
- tim
- antibodies
- methods
- treating cancer
- cancer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/53—Hinge
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762444354P | 2017-01-09 | 2017-01-09 | |
| US201762582272P | 2017-11-06 | 2017-11-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201913083SA true SG10201913083SA (en) | 2020-03-30 |
Family
ID=61163782
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201913083SA SG10201913083SA (en) | 2017-01-09 | 2018-01-09 | Methods of treating cancer with anti-tim-3 antibodies |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11926665B2 (en) |
| EP (1) | EP3565594A1 (en) |
| JP (2) | JP7118073B2 (en) |
| KR (1) | KR102671283B1 (en) |
| CN (1) | CN110382000A (en) |
| AU (1) | AU2018205401A1 (en) |
| BR (1) | BR112019014169A2 (en) |
| CA (1) | CA3049536A1 (en) |
| IL (1) | IL267803A (en) |
| MA (1) | MA47206A (en) |
| MX (1) | MX2019008208A (en) |
| SG (1) | SG10201913083SA (en) |
| TW (1) | TWI793094B (en) |
| WO (1) | WO2018129553A1 (en) |
Families Citing this family (30)
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| CN107743495B (en) | 2015-03-23 | 2021-05-14 | 拜耳制药股份公司 | anti-CEACAM 6 antibodies and uses thereof |
| MA41867A (en) * | 2015-04-01 | 2018-02-06 | Anaptysbio Inc | T-CELL IMMUNOGLOBULIN AND MUCINE PROTEIN 3 ANTIBODIES (TIM-3) |
| MX2019003683A (en) | 2016-10-11 | 2019-08-22 | Agenus Inc | Anti-lag-3 antibodies and methods of use thereof. |
| AU2017354070A1 (en) | 2016-11-01 | 2019-05-16 | Anaptysbio, Inc. | Antibodies directed against programmed death- 1 (PD-1) |
| EP3535586A4 (en) * | 2016-11-01 | 2020-08-05 | AnaptysBio, Inc. | Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3) |
| ES2945745T3 (en) | 2017-01-09 | 2023-07-06 | Tesaro Inc | Methods of treating cancers with anti-PD-1 antibodies |
| AU2018205401A1 (en) * | 2017-01-09 | 2019-07-25 | Tesaro, Inc. | Methods of treating cancer with anti-TIM-3 antibodies |
| MA49144A (en) | 2017-05-18 | 2020-03-25 | Tesaro Inc | POLYTHERAPIES FOR THE TREATMENT OF CANCER |
| MA50657A (en) | 2017-09-26 | 2020-08-05 | Tesaro Inc | NIRAPARIB FORMULATIONS |
| CA3076515A1 (en) | 2017-09-30 | 2019-04-04 | Tesaro, Inc. | Combination therapies for treating cancer |
| CN111182923A (en) | 2017-10-06 | 2020-05-19 | 特沙诺有限公司 | Combination therapy and uses thereof |
| WO2019143607A1 (en) * | 2018-01-16 | 2019-07-25 | Bristol-Myers Squibb Company | Methods of treating cancer with antibodies against tim3 |
| WO2020072797A1 (en) | 2018-10-03 | 2020-04-09 | Tesaro, Inc. | Niraparib salts |
| US20210347758A1 (en) | 2018-10-03 | 2021-11-11 | Tesaro, Inc. | Crystalline Forms of Niraparib Freebase |
| WO2020093023A1 (en) * | 2018-11-01 | 2020-05-07 | Merck Patent Gmbh | Anti-tim-3 antibodies |
| EP3897844B1 (en) | 2018-12-19 | 2023-11-15 | Deutsches Krebsforschungszentrum | Pharmaceutical combination of anti ceacam6 and tim3 antibodies |
| WO2020127377A1 (en) | 2018-12-21 | 2020-06-25 | Ose Immunotherapeutics | Bifunctional anti-pd-1/il-7 molecule |
| US20220089740A1 (en) * | 2019-01-11 | 2022-03-24 | Eli Lilly And Company | Tim-3 antibodies and combinations with other checkpoint inhibitors for the treatment of cancer |
| WO2020165374A1 (en) | 2019-02-14 | 2020-08-20 | Ose Immunotherapeutics | Bifunctional molecule comprising il-15ra |
| AU2020406083A1 (en) | 2019-12-17 | 2022-06-16 | Ose Immunotherapeutics | Bifunctional molecules comprising an IL-7 variant |
| EP4136112A1 (en) | 2020-04-14 | 2023-02-22 | GlaxoSmithKline Intellectual Property Development Limited | Combination treatment for cancer |
| WO2021209357A1 (en) | 2020-04-14 | 2021-10-21 | Glaxosmithkline Intellectual Property Development Limited | Combination treatment for cancer involving anti-icos and anti-pd1 antibodies, optionally further involving anti-tim3 antibodies |
| US20210403568A1 (en) * | 2020-06-29 | 2021-12-30 | Cai Gu Huang | Biopharmaceutical formulation of anti-pd-1, anti-pd-l1, and anti-vegfr therapeutic monoclonal antibodies and method for treating nsclc by inhalation |
| WO2022148781A1 (en) | 2021-01-05 | 2022-07-14 | Institut Curie | Combination of mcoln activators and immune checkpoint inhibitors |
| WO2022214652A1 (en) | 2021-04-09 | 2022-10-13 | Ose Immunotherapeutics | Scaffold for bifunctioanl molecules comprising pd-1 or cd28 and sirp binding domains |
| JP2024515263A (en) | 2021-04-09 | 2024-04-08 | オーエスイー・イミュノセラピューティクス | Novel scaffolds for bifunctional molecules with improved properties |
| US11970548B2 (en) * | 2021-08-27 | 2024-04-30 | Innovative Cellular Therapeutics Holdings, Ltd. | Nanobody target GCC and uses in chimeric antigen receptor cell therapy |
| IL310773A (en) | 2021-09-02 | 2024-04-01 | Deutsches Krebsforschungszentrum Stiftung Des ?Ffentlichen Rechts | Anti-cecam6 antibodies with reduced side-effects |
| WO2024003360A1 (en) | 2022-07-01 | 2024-01-04 | Institut Curie | Biomarkers and uses thereof for the treatment of neuroblastoma |
| WO2024028386A1 (en) | 2022-08-02 | 2024-02-08 | Ose Immunotherapeutics | Multifunctional molecule directed against cd28 |
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| US20150259420A1 (en) | 2014-03-14 | 2015-09-17 | Novartis Ag | Antibody molecules to lag-3 and uses thereof |
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| KR102011205B1 (en) | 2014-11-06 | 2019-08-14 | 에프. 호프만-라 로슈 아게 | Anti-tim3 antibodies and methods of use |
| MA41463A (en) | 2015-02-03 | 2017-12-12 | Anaptysbio Inc | ANTIBODIES DIRECTED AGAINST LYMPHOCYTE ACTIVATION GEN 3 (LAG-3) |
| MA41867A (en) | 2015-04-01 | 2018-02-06 | Anaptysbio Inc | T-CELL IMMUNOGLOBULIN AND MUCINE PROTEIN 3 ANTIBODIES (TIM-3) |
| PL3317301T3 (en) | 2015-07-29 | 2021-11-15 | Novartis Ag | Combination therapies comprising antibody molecules to lag-3 |
| KR20180069070A (en) | 2015-11-03 | 2018-06-22 | 얀센 바이오테크 인코포레이티드 | Antibodies that specifically bind to TIM-3 and uses thereof |
| AR108377A1 (en) | 2016-05-06 | 2018-08-15 | Medimmune Llc | BISPECIFIC UNION PROTEINS AND ITS USES |
| CA3029671C (en) | 2016-06-29 | 2023-08-15 | Tesaro, Inc. | Methods of treating ovarian cancer |
| TW202246347A (en) | 2016-08-26 | 2022-12-01 | 英屬開曼群島商百濟神州有限公司 | Anti-tim-3 antibodies and use thereof |
| EP3535586A4 (en) | 2016-11-01 | 2020-08-05 | AnaptysBio, Inc. | Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3) |
| AU2018205401A1 (en) * | 2017-01-09 | 2019-07-25 | Tesaro, Inc. | Methods of treating cancer with anti-TIM-3 antibodies |
| AR111651A1 (en) * | 2017-04-28 | 2019-08-07 | Novartis Ag | CONJUGATES OF ANTIBODIES THAT INCLUDE TOLL TYPE RECEIVER AGONISTS AND COMBINATION THERAPIES |
-
2018
- 2018-01-09 AU AU2018205401A patent/AU2018205401A1/en active Pending
- 2018-01-09 CA CA3049536A patent/CA3049536A1/en active Pending
- 2018-01-09 JP JP2019537099A patent/JP7118073B2/en active Active
- 2018-01-09 US US16/476,534 patent/US11926665B2/en active Active
- 2018-01-09 KR KR1020197023158A patent/KR102671283B1/en active IP Right Grant
- 2018-01-09 MX MX2019008208A patent/MX2019008208A/en unknown
- 2018-01-09 CN CN201880016126.4A patent/CN110382000A/en active Pending
- 2018-01-09 SG SG10201913083SA patent/SG10201913083SA/en unknown
- 2018-01-09 BR BR112019014169-3A patent/BR112019014169A2/en unknown
- 2018-01-09 TW TW107100821A patent/TWI793094B/en active
- 2018-01-09 WO PCT/US2018/013021 patent/WO2018129553A1/en unknown
- 2018-01-09 EP EP18703388.1A patent/EP3565594A1/en active Pending
- 2018-01-09 MA MA047206A patent/MA47206A/en unknown
-
2019
- 2019-07-02 IL IL267803A patent/IL267803A/en unknown
-
2022
- 2022-04-05 JP JP2022062862A patent/JP7472190B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| IL267803A (en) | 2019-09-26 |
| JP2022087185A (en) | 2022-06-09 |
| CA3049536A1 (en) | 2018-07-12 |
| CN110382000A (en) | 2019-10-25 |
| MA47206A (en) | 2019-11-13 |
| JP7472190B2 (en) | 2024-04-22 |
| KR20190098263A (en) | 2019-08-21 |
| JP7118073B2 (en) | 2022-08-15 |
| JP2020503364A (en) | 2020-01-30 |
| TW202319068A (en) | 2023-05-16 |
| EP3565594A1 (en) | 2019-11-13 |
| US20190322746A1 (en) | 2019-10-24 |
| BR112019014169A2 (en) | 2020-02-11 |
| TW201831196A (en) | 2018-09-01 |
| MX2019008208A (en) | 2019-12-11 |
| TWI793094B (en) | 2023-02-21 |
| AU2018205401A1 (en) | 2019-07-25 |
| KR102671283B1 (en) | 2024-06-03 |
| WO2018129553A1 (en) | 2018-07-12 |
| US11926665B2 (en) | 2024-03-12 |
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