|
EP0290762B1
(en)
|
1984-10-04 |
1993-05-12 |
Sandoz Ag |
Cyclosporins
|
|
CA2014590C
(en)
|
1989-04-15 |
1999-12-14 |
Mitsuo Masaki |
Novel peptides, and antidementia agents containing the same
|
|
ATE138807T1
(de)
|
1992-03-27 |
1996-06-15 |
American Home Prod |
29-demethoxyrapamycin zur induktion der immunosuppression
|
|
CA2171629A1
(en)
|
1993-09-20 |
1995-03-30 |
Chaitan Khosla |
Recombinant production of novel polyketides
|
|
IL112873A
(en)
|
1994-03-08 |
2005-03-20 |
Wyeth Corp |
Rapamycin-fkbp12 binding proteins, their isolation and their use
|
|
GB9410142D0
(en)
|
1994-05-20 |
1994-07-06 |
Univ Warwick |
Carbapenems
|
|
GB9524630D0
(en)
|
1994-12-24 |
1996-01-31 |
Zeneca Ltd |
Chemical compounds
|
|
US6124453A
(en)
|
1995-07-04 |
2000-09-26 |
Novartis Ag |
Macrolides
|
|
CA2197524A1
(en)
*
|
1996-02-22 |
1997-08-22 |
Bradley Stuart Dehoff |
Polyketide synthase genes
|
|
ES2244001T3
(es)
|
1996-07-05 |
2005-12-01 |
Biotica Technology Limited |
Eritromicinas y procedimiento para su preparacion.
|
|
SE9603465D0
(sv)
|
1996-09-23 |
1996-09-23 |
Astra Ab |
New compounds
|
|
US6902913B2
(en)
|
1997-04-30 |
2005-06-07 |
Kosan Biosciences, Inc. |
Recombinant narbonolide polyketide synthase
|
|
US6153383A
(en)
|
1997-12-09 |
2000-11-28 |
Verdine; Gregory L. |
Synthetic transcriptional modulators and uses thereof
|
|
AU4093799A
(en)
|
1998-05-22 |
1999-12-13 |
Board Of Trustees Of The Leland Stanford Junior University |
Bifunctional molecules and therapies based thereon
|
|
MXPA01003376A
(es)
|
1998-10-02 |
2002-11-07 |
Kosan Biosciences Inc |
Enzimas policetido sintetasa y construcciones de acido desoxirribonucleico recombinante para las mismas.
|
|
US6686454B1
(en)
|
1998-10-09 |
2004-02-03 |
Isotechnika, Inc. |
Antibodies to specific regions of cyclosporine related compounds
|
|
US6753173B1
(en)
|
1999-02-09 |
2004-06-22 |
Board Of Trustees Of The Leland Stanford Junior University |
Methods to mediate polyketide synthase module effectiveness
|
|
GB9927191D0
(en)
|
1999-11-17 |
2000-01-12 |
Angeletti P Ist Richerche Bio |
Methods and means for regulation of gene expression
|
|
EP1230353A4
(en)
|
1999-11-19 |
2002-11-06 |
Univ Leland Stanford Junior |
BIFUNCTIONAL MOLECULES AND THEIR USE IN THE DESTRUCTION OF PROTEIN-PROTEIN INTERACTIONS
|
|
US7220552B1
(en)
|
1999-11-19 |
2007-05-22 |
The Board Of Trustees Of The Leland Stanford Junior University |
Bifunctional molecules and their use in the disruption of protein-protein interactions
|
|
US7141660B2
(en)
*
|
2000-02-08 |
2006-11-28 |
Sinvent As |
Genes encoding a nystatin polyketide synthase and their manipulation and utility
|
|
KR20020025959A
(ko)
|
2000-05-23 |
2002-04-04 |
버텍스 파마슈티칼스 인코포레이티드 |
카스파제 억제제 및 이의 용도
|
|
US7198924B2
(en)
*
|
2000-12-11 |
2007-04-03 |
Invitrogen Corporation |
Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
|
|
WO2003014311A2
(en)
*
|
2001-08-06 |
2003-02-20 |
Kosan Biosciences, Inc. |
Methods for altering polyketide synthase genes
|
|
US6809077B2
(en)
|
2001-10-12 |
2004-10-26 |
Enanta Pharmaceuticals, Inc. |
Cyclosporin analogs for the treatment of autoimmune diseases
|
|
US6987090B2
(en)
|
2002-05-09 |
2006-01-17 |
Lg Household & Health Care Ltd. |
Use of 3-position cyclosporin derivatives for hair growth
|
|
EP1477563A3
(en)
|
2003-05-16 |
2004-11-24 |
Wyeth |
Cloning genes from streptomyces cyaneogriseus subsp.noncyanogenus for biosynthesis of antibiotics and methods of use
|
|
CA2643826A1
(en)
|
2006-02-27 |
2008-06-12 |
Paul A. Wender |
Compositions and methods for transport of molecules with enhanced release properties across biological barriers
|
|
US20070203168A1
(en)
|
2006-02-28 |
2007-08-30 |
Zhao Jonathon Z |
Isomers of rapamycin and 42-Epi-rapamycin, methods of making and using the same
|
|
KR100945483B1
(ko)
|
2007-10-25 |
2010-03-05 |
이화여자대학교 산학협력단 |
ｐｉｋＤ 조절유전자의 발현벡터를 이용한 스트렙토미세스베네주엘라에（Ｓｔｒｅｐｔｏｍｙｃｅｓｖｅｎｅｚｕｅｌａｅ）에서폴리케타이드（ｐｏｌｙｋｅｔｉｄｅ）의 생산성 증가방법
|
|
GB0805363D0
(en)
*
|
2008-03-20 |
2008-04-30 |
Sinvent As |
Novel NRPS-PKS gene cluster and its manipulation and utility
|
|
WO2010031185A1
(en)
|
2008-09-19 |
2010-03-25 |
Protox Therapeutics Inc. |
Treating cancer stem cells using targeted cargo proteins
|
|
CN102224242B
(zh)
|
2008-09-24 |
2014-09-24 |
中国科学院上海有机化学研究所 |
新基因簇
|
|
KR20110111321A
(ko)
|
2009-01-30 |
2011-10-10 |
이난타 파마슈티칼스, 인코포레이티드 |
Ｃ형 간염을 예방하거나 치료하기 위한 사이클로스포린 유사체
|
|
AU2010273220B2
(en)
|
2009-07-13 |
2015-10-15 |
President And Fellows Of Harvard College |
Bifunctional stapled polypeptides and uses thereof
|
|
US8664186B2
(en)
|
2009-07-24 |
2014-03-04 |
Universite De Lorraine |
Stambomycin and derivatives, their production and their uses as drugs
|
|
CN102712675A
(zh)
|
2009-09-22 |
2012-10-03 |
爱勒让治疗公司 |
拟肽大环化合物
|
|
WO2011049157A1
(ja)
|
2009-10-22 |
2011-04-28 |
ペプチドリーム株式会社 |
ペプチド翻訳合成におけるrapidディスプレイ法
|
|
US9250237B2
(en)
|
2010-11-30 |
2016-02-02 |
The Johns Hopkins University |
Hybrid cyclic libraries and screens thereof
|
|
US9428845B1
(en)
|
2010-12-28 |
2016-08-30 |
Warp Drive Bio, Inc. |
Identifying new therapeutic agents
|
|
WO2012174489A2
(en)
|
2011-06-15 |
2012-12-20 |
The Ohio State University |
Small molecule composite surfaces as inhibitors of protein-protein interactions
|
|
ES2781523T3
(es)
|
2012-07-12 |
2020-09-02 |
Hangzhou Dac Biotech Co Ltd |
Conjugados de moléculas de unión celular con agentes citotóxicos
|
|
CA2891280C
(en)
|
2012-11-24 |
2018-03-20 |
Hangzhou Dac Biotech Co., Ltd. |
Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
|
|
EP2806274A1
(en)
|
2013-05-24 |
2014-11-26 |
AIT Austrian Institute of Technology GmbH |
Lung cancer diagnostic method and means
|
|
US10233431B2
(en)
|
2014-02-26 |
2019-03-19 |
The Regents Of The University Of California |
Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases
|
|
WO2015132784A1
(en)
|
2014-03-03 |
2015-09-11 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. |
Method and device for detection of pseudomonas aeruginosa
|
|
US11479797B2
(en)
|
2016-10-28 |
2022-10-25 |
Ginkgo Bioworks, Inc. |
Compositions and methods for the production of compounds
|