|
EP2948544A4
(en)
|
2013-01-28 |
2016-08-03 |
St Jude Childrens Res Hospital |
CHIMERIC RECEPTOR WITH NKG2D SPECIFICITY FOR CELL THERAPY AGAINST CANCER AND INFECTION DISEASES
|
|
WO2015142314A1
(en)
*
|
2013-03-15 |
2015-09-24 |
Memorial Sloan-Kettering Cancer Center |
Compositions and methods for immunotherapy
|
|
AU2014248119B2
(en)
*
|
2013-04-03 |
2019-06-20 |
Memorial Sloan-Kettering Cancer Center |
Effective generation of tumor-targeted T-cells derived from pluripotent stem cells
|
|
US20160296562A1
(en)
|
2013-11-21 |
2016-10-13 |
Ucl Business Plc |
Cell
|
|
AU2015259877B2
(en)
|
2014-05-15 |
2021-02-25 |
National University Of Singapore |
Modified natural killer cells and uses thereof
|
|
US11072644B2
(en)
|
2014-11-12 |
2021-07-27 |
Allogene Therapeutics, Inc. |
Inhibitory chimeric antigen receptors
|
|
CA2969456A1
(en)
|
2014-12-03 |
2016-06-09 |
Juno Therapeutics, Inc. |
Methods and compositions for adoptive cell therapy
|
|
KR102376244B1
(ko)
|
2014-12-24 |
2022-03-21 |
오토러스 리미티드 |
세포
|
|
AU2016211671B2
(en)
|
2015-01-26 |
2022-05-26 |
Fate Therapeutics, Inc. |
Methods and compositions for inducing hematopoietic cell differentiation
|
|
JP7237449B2
(ja)
*
|
2015-02-27 |
2023-03-13 |
アイセル・ジーン・セラピューティクス・エルエルシー |
血液系腫瘍を標的としたキメラ抗体受容体（ＣＡＲｓ）の構成およびその使用方法
|
|
WO2016179319A1
(en)
*
|
2015-05-04 |
2016-11-10 |
Cellerant Therapeutics, Inc. |
Chimeric antigen receptors with ctla4 signal transduction domains
|
|
CN107995913B
(zh)
|
2015-05-18 |
2022-02-11 |
T细胞受体治疗公司 |
使用融合蛋白对tcr重编程的组合物和方法
|
|
GB201509413D0
(en)
*
|
2015-06-01 |
2015-07-15 |
Ucl Business Plc |
Fusion protein
|
|
WO2017040945A1
(en)
|
2015-09-04 |
2017-03-09 |
Memorial Sloan Kettering Cancer Center |
Immune cell compositions and methods of use
|
|
WO2017058753A1
(en)
*
|
2015-09-28 |
2017-04-06 |
Trustees Of Dartmouth College |
Chimeric antigen receptor, regulatory cells and methods of use
|
|
CA3003152A1
(en)
|
2015-11-04 |
2017-05-11 |
Fate Therapeutics, Inc. |
Methods and compositions for inducing hematopoietic cell differentiation
|
|
JP6928604B2
(ja)
|
2015-11-04 |
2021-09-01 |
フェイト セラピューティクス，インコーポレイテッド |
万能性細胞のゲノム改変
|
|
EP3377523A4
(en)
*
|
2015-11-19 |
2019-06-19 |
The Regents of The University of California |
CONDITIONALLY REPRIMATABLE IMMUNOCELL RECEPTORS AND METHOD FOR USE THEREOF
|
|
WO2017100428A1
(en)
|
2015-12-09 |
2017-06-15 |
Memorial Sloan Kettering Cancer Center |
Immune cell compositions and methods of using same
|
|
CN109073635A
(zh)
|
2016-01-25 |
2018-12-21 |
豪夫迈·罗氏有限公司 |
用于测定t细胞依赖性双特异性抗体的方法
|
|
CN105567640A
(zh)
*
|
2016-01-27 |
2016-05-11 |
苏州佰通生物科技有限公司 |
一种嵌合抗原受体脂肪干细胞及其制备方法
|
|
CA3018253A1
(en)
*
|
2016-03-31 |
2017-10-05 |
University Of Southern California |
A highly sensitive and specific luciferase based reporter assay for antigen detection
|
|
CN109414512A
(zh)
|
2016-04-22 |
2019-03-01 |
科济生物医药（上海）有限公司 |
用于细胞免疫疗法的组合物和方法
|
|
NZ749136A
(en)
*
|
2016-05-25 |
2023-11-24 |
Council Queensland Inst Medical Res |
Methods of immunotherapy
|
|
CN105950561A
(zh)
*
|
2016-05-26 |
2016-09-21 |
江苏杰晟生物科技有限公司 |
一种靶向乳腺癌干细胞的双特异性嵌合抗原受体基因修饰的t淋巴细胞的制备方法及其产品
|
|
MX2018014991A
(es)
*
|
2016-06-03 |
2019-08-29 |
Memorial Sloan Kettering Cancer Center |
Terapias adoptivas de celulas como opciones de tratamiento temprano.
|
|
EP3494138A1
(en)
|
2016-08-02 |
2019-06-12 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
GB201614162D0
(en)
*
|
2016-08-18 |
2016-10-05 |
Polytherics Ltd |
Antibodies, uses thereof and conjugates thereof
|
|
CA3034691A1
(en)
|
2016-08-30 |
2018-03-08 |
Memorial Sloan Kettering Cancer Center |
Immune cell compositions and methods of use for treating viral and other infections
|
|
MX2019003462A
(es)
*
|
2016-09-28 |
2019-08-16 |
Gavish Galilee Bio Appl Ltd |
Una plataforma universal para el tratamiento con car que se dirige a una novedosa firma antigenica del cancer.
|
|
CA3036745A1
(en)
|
2016-10-07 |
2018-04-12 |
TCR2 Therapeutics Inc. |
Compositions and methods for t-cell receptors reprogramming using fusion proteins
|
|
CN107988164B
(zh)
|
2016-10-26 |
2020-07-07 |
阿思科力(苏州)生物科技有限公司 |
一种pd-1 car nk-92细胞及其制备方法与应用
|
|
EP3315511A1
(en)
*
|
2016-10-29 |
2018-05-02 |
Miltenyi Biotec GmbH |
Adapter chimeric antigen receptor expressing cells for targeting of multiple antigens
|
|
US11851491B2
(en)
|
2016-11-22 |
2023-12-26 |
TCR2 Therapeutics Inc. |
Compositions and methods for TCR reprogramming using fusion proteins
|
|
CN108204958A
(zh)
*
|
2016-12-19 |
2018-06-26 |
伊缪泰普有限公司 |
结合测定
|
|
US11590214B2
(en)
*
|
2016-12-21 |
2023-02-28 |
Danmarks Tekniskte Universitet |
Antigen presenting scaffolds for immune-cell manipulation
|
|
WO2018124766A2
(ko)
|
2016-12-28 |
2018-07-05 |
주식회사 녹십자랩셀 |
키메라 항원 수용체 및 이를 발현하는 자연 살해 세포
|
|
AU2018231190B2
(en)
*
|
2017-03-08 |
2023-05-25 |
Memorial Sloan Kettering Cancer Center |
Immune cell compositions and methods of use
|
|
KR102660336B1
(ko)
|
2017-03-27 |
2024-04-26 |
내셔널 유니버시티 오브 싱가포르 |
절단된 nkg2d 키메라 수용체 및 자연 살해 세포 면역요법에서의 그의 용도
|
|
MX2019011570A
(es)
|
2017-03-27 |
2019-11-18 |
Nat Univ Singapore |
Lineas celulares estimuladoras para expansion y activacion ex vivo de celulas asesinas naturales.
|
|
CN109097402B
(zh)
*
|
2017-03-31 |
2021-09-07 |
国健呈诺生物科技(北京)有限公司 |
一种重组载体CAR-CD244-antiCD19的制备方法
|
|
WO2018195339A1
(en)
*
|
2017-04-19 |
2018-10-25 |
Board Of Regents, The University Of Texas System |
Immune cells expressing engineered antigen receptors
|
|
GB201707779D0
(en)
*
|
2017-05-15 |
2017-06-28 |
Autolus Ltd |
Cell
|
|
CN111201438A
(zh)
*
|
2017-06-02 |
2020-05-26 |
朱诺治疗学股份有限公司 |
与和细胞疗法相关的毒性有关的制品和方法
|
|
KR20200071740A
(ko)
*
|
2017-09-28 |
2020-06-19 |
임팩트-바이오 리미티드. |
저해성 키메라 항원 수용체 (icar)를 제조하기 위한 보편적 플랫폼
|
|
CN109593721B
(zh)
*
|
2017-09-30 |
2022-11-01 |
亘喜生物科技（上海）有限公司 |
具有自杀基因开关的靶向人间皮素的工程化免疫细胞
|
|
GB201717524D0
(en)
|
2017-10-25 |
2017-12-06 |
Autolus Ltd |
Vectors
|
|
US11649294B2
(en)
|
2017-11-14 |
2023-05-16 |
GC Cell Corporation |
Anti-HER2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same
|
|
US12116417B2
(en)
|
2017-11-14 |
2024-10-15 |
GC Cell Corporation |
Anti-HER2 antibody or antigen-binding fragment thereof, and chimeric antigen receptor comprising same
|
|
EP3720882A4
(en)
|
2017-12-05 |
2021-10-27 |
The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center |
T-CELLS WITH TWO DIFFERENT CHIMERIC ANTIGEN RECEPTORS AND THEIR USE
|
|
IL316570A
(en)
*
|
2017-12-05 |
2024-12-01 |
Medical Res Infrastructure & Health Services Fund Tel Aviv Medical Ct |
T cells containing chimeric receptors for CD138 and CD38 antigens and their use
|
|
GB201721802D0
(en)
*
|
2017-12-22 |
2018-02-07 |
Almac Discovery Ltd |
Ror1-specific antigen binding molecules
|
|
SG11202006050XA
(en)
*
|
2017-12-29 |
2020-07-29 |
Memorial Sloan Kettering Cancer Center |
Enhanced chimeric antigen receptors and uses thereof
|
|
US12491153B2
(en)
|
2018-01-03 |
2025-12-09 |
Qu Biologics Inc. |
Innate targeting of adoptive cellular therapies
|
|
AU2019219454A1
(en)
|
2018-02-09 |
2020-08-27 |
National University Of Singapore |
Activating chimeric receptors and uses thereof in natural killer cell immunotherapy
|
|
CN109321530B
(zh)
*
|
2018-02-12 |
2021-03-12 |
华东师范大学 |
一种安全型嵌合抗原受体t细胞及其用途
|
|
JP7273421B2
(ja)
|
2018-02-21 |
2023-05-15 |
ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム |
ナチュラルキラー細胞の活性化および拡大のための方法ならびにその使用
|
|
CN112055717B
(zh)
|
2018-04-02 |
2024-04-26 |
新加坡国立大学 |
用在免疫细胞中表达的膜结合抗细胞因子非信号传导粘合剂中和人细胞因子
|
|
US20210145881A1
(en)
*
|
2018-04-09 |
2021-05-20 |
Mayo Foundation For Medical Education And Research |
Methods and materials for treating graft-versus-host disease
|
|
CN110526976A
(zh)
*
|
2018-05-25 |
2019-12-03 |
深圳宾德生物技术有限公司 |
一种靶向psma的单链抗体、嵌合抗原受体t细胞及其制备方法和应用
|
|
CN110526984A
(zh)
*
|
2018-05-25 |
2019-12-03 |
深圳宾德生物技术有限公司 |
一种靶向psma的嵌合抗原受体、嵌合抗原受体t细胞及其制备方法和应用
|
|
CN119529091A
(zh)
*
|
2018-06-19 |
2025-02-28 |
南京传奇生物科技有限公司 |
工程化的细胞及其用途
|
|
TW202016144A
(zh)
*
|
2018-06-21 |
2020-05-01 |
日商第一三共股份有限公司 |
包括cd3抗原結合片段之組成物及其用途
|
|
EP3844186A4
(en)
|
2018-08-29 |
2022-08-17 |
National University of Singapore |
METHOD OF SPECIFIC STIMULATION OF SURVIVAL AND EXPANSION OF GENETICALLY MODIFIED IMMUNE CELLS
|
|
CA3114788A1
(en)
*
|
2018-09-28 |
2020-04-02 |
Memorial Sloan-Kettering Cancer Center |
Immunoresponsive cells expressing dominant negative fas and uses thereof
|
|
US20200316120A1
(en)
*
|
2018-09-28 |
2020-10-08 |
Immpact-Bio Ltd. |
METHODS FOR IDENTIFYING ACTIVATING ANTIGEN RECEPTOR (aCAR)/INHIBITORY CHIMERIC ANTIGEN RECEPTOR (iCAR) PAIRS FOR USE IN CANCER THERAPIES
|
|
US12331320B2
(en)
|
2018-10-10 |
2025-06-17 |
The Research Foundation For The State University Of New York |
Genome edited cancer cell vaccines
|
|
WO2020092736A1
(en)
|
2018-10-31 |
2020-05-07 |
Mayo Foundation For Medical Education And Research |
Methods and materials for treating cancer
|
|
US12264189B2
(en)
|
2018-10-31 |
2025-04-01 |
Mayo Foundation For Medical Education And Research |
Methods and materials for treating cancer
|
|
US12466892B2
(en)
|
2018-11-08 |
2025-11-11 |
The Regents Of The University Of California |
Systems and methods for targeting cancer cells
|
|
US12590148B2
(en)
|
2018-11-26 |
2026-03-31 |
Nkarta, Inc. |
Methods for the simultaneous expansion of multiple immune cell types, related compositions and uses of same in cancer immunotherapy
|
|
CN109517799B
(zh)
*
|
2018-11-30 |
2022-07-26 |
北京美康基免生物科技有限公司 |
一种基于cd19和cd22的双重嵌合抗原受体基因修饰的免疫细胞及其应用
|
|
US20220133791A1
(en)
|
2019-01-23 |
2022-05-05 |
Miltenyi Biotec B.V. & Co. KG |
A Combination of compositions for elimination and enhanced engraftment of hematopoietic stem cells in the bone marrow of a subject
|
|
CA3130489A1
(en)
*
|
2019-02-18 |
2020-08-27 |
Memorial Sloan-Kettering Cancer Center |
Combinations of multiple chimeric antigen receptors for immunotherapy
|
|
AU2020232691B2
(en)
|
2019-03-05 |
2023-06-29 |
Nkarta, Inc. |
CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
|
|
EP3962527A4
(en)
|
2019-04-30 |
2023-11-01 |
Senti Biosciences, Inc. |
CHIMERIC RECEPTORS AND METHODS OF USE THEREOF
|
|
CN110592014A
(zh)
*
|
2019-08-14 |
2019-12-20 |
广东美赛尔细胞生物科技有限公司 |
一种在nk细胞治疗中免辐照体外体内持续去除饲养细胞的方法
|
|
JP2022546315A
(ja)
*
|
2019-08-20 |
2022-11-04 |
センティ バイオサイエンシズ インコーポレイテッド |
キメラ抑制性受容体
|
|
JP2022545541A
(ja)
*
|
2019-08-28 |
2022-10-27 |
センティ バイオサイエンシズ インコーポレイテッド |
組み合わせがん免疫療法
|
|
EP4025594A2
(en)
*
|
2019-09-05 |
2022-07-13 |
Migal Galilee Research Institute Ltd. |
Blocking chimeric antigen receptors for prevention of undesired activation of effector and regulatory immune cells
|
|
US20220372092A1
(en)
*
|
2019-10-18 |
2022-11-24 |
Board Of Regents, The University Of Texas System |
Hla-restricted vcx/y peptides and t cell receptors and use thereof
|
|
EP4073103A1
(en)
|
2019-12-11 |
2022-10-19 |
A2 Biotherapeutics, Inc. |
Lilrb1-based chimeric antigen receptor
|
|
EP4100027A1
(en)
|
2020-02-04 |
2022-12-14 |
Miltenyi Biotec B.V. & Co. KG |
Immune cell expressing adapter chimeric antigen receptor for sensing soluble antigens
|
|
CN115397845A
(zh)
*
|
2020-02-20 |
2022-11-25 |
森迪生物科学公司 |
抑制性嵌合受体架构
|
|
CN111249314B
(zh)
*
|
2020-03-03 |
2022-03-29 |
深圳未知君生物科技有限公司 |
人体共生菌群在提高肿瘤免疫治疗应答中的作用
|
|
JP2023525910A
(ja)
*
|
2020-05-20 |
2023-06-19 |
ミルテニイ ビオテック ベー．ファー． ウント コー．カーゲー |
Ｃｄ９０およびｃｄ３２６を発現しているがんを処置するための組成物および方法
|
|
US12286465B2
(en)
|
2020-05-28 |
2025-04-29 |
Miltenyi Biotec B.V. & Co. KG |
Chimeric antigen receptor with a spacer comprising C2-set Ig-like domains
|
|
WO2022007784A1
(en)
*
|
2020-07-06 |
2022-01-13 |
Nanjing Legend Biotech Co., Ltd. |
Methods of reducing graft rejection of allogeneic cell therapy
|
|
WO2022015955A1
(en)
|
2020-07-16 |
2022-01-20 |
Umoja Biopharma, Inc. |
Gated adapter targeting receptor
|
|
WO2022036065A2
(en)
*
|
2020-08-13 |
2022-02-17 |
A2 Biotherapeutics, Inc. |
Compositions and methods for treating cancers
|
|
CN113527491B
(zh)
*
|
2020-08-19 |
2023-06-20 |
苏州易慕峰生物科技有限公司 |
人源化抗体、嵌合抗原受体、核酸、载体、细胞及应用
|
|
AU2021328478A1
(en)
|
2020-08-20 |
2023-04-20 |
A2 Biotherapeutics, Inc. |
Compositions and methods for treating egfr positive cancers
|
|
WO2022040454A1
(en)
|
2020-08-20 |
2022-02-24 |
A2 Biotherapeutics, Inc. |
Compositions and methods for treating mesothelin positive cancers
|
|
KR102859550B1
(ko)
|
2020-08-20 |
2025-09-16 |
에이투 바이오쎄라퓨틱스, 인크. |
Ceacam 양성 암을 치료하기 위한 조성물 및 방법
|
|
US20220090015A1
(en)
|
2020-09-21 |
2022-03-24 |
A2 Biotherapeutics, Inc. |
Engineered immune cells with multiplex and localized activity
|
|
US20230405047A1
(en)
|
2020-11-09 |
2023-12-21 |
Miltenyi Biotec B.V. & Co. KG |
Methods and compositions for eliminating engineered immune cells
|
|
WO2022116877A1
(en)
|
2020-12-02 |
2022-06-09 |
Shanghai Henlius Biotech, Inc. |
ANTI-GARP/TGFβ ANTIBODIES AND METHODS OF USE
|
|
CN114569708B
(zh)
*
|
2020-12-02 |
2023-07-04 |
四川大学华西医院 |
Nkg2d car-免疫细胞在抗衰老中应用
|
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
|
AU2021392032A1
(en)
|
2020-12-03 |
2023-06-22 |
Century Therapeutics, Inc. |
Genetically engineered cells and uses thereof
|
|
US20240042028A1
(en)
*
|
2020-12-07 |
2024-02-08 |
The Johns Hopkins University |
Methods of nk cell engineering to enhance tumor targeting
|
|
AR124414A1
(es)
|
2020-12-18 |
2023-03-22 |
Century Therapeutics Inc |
Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable
|
|
US20240082306A1
(en)
*
|
2021-02-03 |
2024-03-14 |
Bioheng Therapeutics Limited |
Novel chimeric antigen receptor and use thereof
|
|
IL304857A
(en)
|
2021-02-16 |
2023-10-01 |
A2 Biotherapeutics Inc |
Preparations and methods for treating HER2 POSITIVE cancer
|
|
AU2022245215A1
(en)
*
|
2021-03-22 |
2023-10-12 |
Memorial Hospital For Cancer And Allied Diseases |
Cd38 chimeric co-stimulating receptor and uses thereof
|
|
WO2023057285A1
(en)
|
2021-10-06 |
2023-04-13 |
Miltenyi Biotec B.V. & Co. KG |
Method for targeted gene insertion into immune cells
|
|
JP2025501522A
(ja)
|
2021-12-17 |
2025-01-22 |
シャンハイ・ヘンリウス・バイオテック・インコーポレイテッド |
抗ｏｘ４０抗体及び使用方法
|
|
CN118488965A
(zh)
|
2021-12-17 |
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