JP2021505604A5 - - Google Patents

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Publication number
JP2021505604A5
JP2021505604A5 JP2020531041A JP2020531041A JP2021505604A5 JP 2021505604 A5 JP2021505604 A5 JP 2021505604A5 JP 2020531041 A JP2020531041 A JP 2020531041A JP 2020531041 A JP2020531041 A JP 2020531041A JP 2021505604 A5 JP2021505604 A5 JP 2021505604A5
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JP
Japan
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cancer
immunotherapy
composition
cells
optionally
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Pending
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JP2020531041A
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English (en)
Japanese (ja)
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JP2021505604A (ja
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Priority claimed from PCT/EP2018/084018 external-priority patent/WO2019110815A1/en
Publication of JP2021505604A publication Critical patent/JP2021505604A/ja
Publication of JP2021505604A5 publication Critical patent/JP2021505604A5/ja
Priority to JP2024000190A priority Critical patent/JP2024028380A/ja
Pending legal-status Critical Current

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JP2020531041A 2017-12-07 2018-12-07 ダサチニブ及び他のチロシンキナーゼ阻害剤を用いる遺伝子改変されたキメラ抗原受容体t細胞の機能の制御及び調節 Pending JP2021505604A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024000190A JP2024028380A (ja) 2017-12-07 2024-01-04 ダサチニブ及び他のチロシンキナーゼ阻害剤を用いる遺伝子改変されたキメラ抗原受容体t細胞の機能の制御及び調節

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17205922.2 2017-12-07
EP17205922 2017-12-07
PCT/EP2018/084018 WO2019110815A1 (en) 2017-12-07 2018-12-07 Control and modulation of the function of gene-modified chimeric antigen receptor t cells with dasatinib and other tyrosine kinase inhibitors

Related Child Applications (1)

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JP2024000190A Division JP2024028380A (ja) 2017-12-07 2024-01-04 ダサチニブ及び他のチロシンキナーゼ阻害剤を用いる遺伝子改変されたキメラ抗原受容体t細胞の機能の制御及び調節

Publications (2)

Publication Number Publication Date
JP2021505604A JP2021505604A (ja) 2021-02-18
JP2021505604A5 true JP2021505604A5 (https=) 2022-01-11

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ID=60629513

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020531041A Pending JP2021505604A (ja) 2017-12-07 2018-12-07 ダサチニブ及び他のチロシンキナーゼ阻害剤を用いる遺伝子改変されたキメラ抗原受容体t細胞の機能の制御及び調節
JP2024000190A Pending JP2024028380A (ja) 2017-12-07 2024-01-04 ダサチニブ及び他のチロシンキナーゼ阻害剤を用いる遺伝子改変されたキメラ抗原受容体t細胞の機能の制御及び調節

Family Applications After (1)

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JP2024000190A Pending JP2024028380A (ja) 2017-12-07 2024-01-04 ダサチニブ及び他のチロシンキナーゼ阻害剤を用いる遺伝子改変されたキメラ抗原受容体t細胞の機能の制御及び調節

Country Status (6)

Country Link
US (2) US20210169880A1 (https=)
EP (1) EP3720477A1 (https=)
JP (2) JP2021505604A (https=)
CN (1) CN111699001A (https=)
CA (1) CA3084873A1 (https=)
WO (1) WO2019110815A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018183888A2 (en) * 2017-03-31 2018-10-04 The Board Of Trustees Of The Leland Stanford Junior University Methods of treating t cell exhaustion by inhibiting or modulating t cell receptor signaling
KR20210135255A (ko) * 2019-03-01 2021-11-12 내셔널 유니버시티 오브 싱가포르 조작된 면역 세포
BR112022001418A2 (pt) * 2019-08-08 2022-06-07 Rigel Pharmaceuticals Inc Compostos e método para tratar a síndrome de liberação de citocinas
CN112480263A (zh) * 2019-09-12 2021-03-12 普米斯生物技术(苏州)有限公司 一种双特异t细胞激活器活化t细胞的设计及其应用
CN111892661B (zh) * 2020-08-12 2021-05-14 浙江康佰裕生物科技有限公司 一种嵌合抗原受体及其在制备治疗肿瘤的产品中的应用
CN116322691A (zh) * 2020-09-24 2023-06-23 豪夫迈·罗氏有限公司 T细胞双特异性抗体相关不良反应的预防或减轻
AU2022227686A1 (en) 2021-02-25 2023-07-27 Lyell Immunopharma, Inc. Ror1 targeting chimeric antigen receptor
CN115348870B (zh) * 2021-03-16 2023-06-13 上海驯鹿生物技术有限公司 通用型嵌合抗原受体t细胞及其应用
WO2022210487A1 (ja) * 2021-03-29 2022-10-06 タカラバイオ株式会社 抗原に特異的な受容体を発現する免疫細胞の製造方法
EP4071248A1 (en) 2021-04-07 2022-10-12 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Means and methods for enhancing receptor-targeted gene transfer
CN113699107B (zh) * 2021-10-27 2022-02-01 东莞再立健生物科技有限公司 一种外周血nkt细胞培养液及培养方法
CN116121196B (zh) * 2022-12-23 2025-07-22 广州安捷生物医学技术有限公司 一种调控car-t细胞的方法与应用
CN121574919A (zh) * 2024-06-19 2026-02-27 徐州医科大学 一种诱导或富集Tscm或Tcm细胞的方法及其应用
CN119060951B (zh) * 2024-11-05 2025-02-14 星奕昂(上海)生物科技有限公司 一种高密度培养条件下提高nk细胞活率的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011034919A2 (en) * 2009-09-15 2011-03-24 H. Lee Moffitt Cancer Center And Research Institute, Inc. Sh2 domain profiling to characterize tyrosine phosphorylation signaling in cancer
WO2017172981A2 (en) * 2016-03-29 2017-10-05 University Of Southern California Chimeric antigen receptors targeting cancer
WO2018183888A2 (en) * 2017-03-31 2018-10-04 The Board Of Trustees Of The Leland Stanford Junior University Methods of treating t cell exhaustion by inhibiting or modulating t cell receptor signaling

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