JP2020108398A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020108398A5 JP2020108398A5 JP2020048623A JP2020048623A JP2020108398A5 JP 2020108398 A5 JP2020108398 A5 JP 2020108398A5 JP 2020048623 A JP2020048623 A JP 2020048623A JP 2020048623 A JP2020048623 A JP 2020048623A JP 2020108398 A5 JP2020108398 A5 JP 2020108398A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid encoding
- car
- producing
- interleukin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000039446 nucleic acids Human genes 0.000 claims 30
- 108020004707 nucleic acids Proteins 0.000 claims 30
- 150000007523 nucleic acids Chemical class 0.000 claims 30
- 108010019670 Chimeric Antigen Receptors Proteins 0.000 claims 24
- 210000001744 T-lymphocyte Anatomy 0.000 claims 15
- 102100036842 C-C motif chemokine 19 Human genes 0.000 claims 10
- 101000713106 Homo sapiens C-C motif chemokine 19 Proteins 0.000 claims 10
- 102000000704 Interleukin-7 Human genes 0.000 claims 10
- 108010002586 Interleukin-7 Proteins 0.000 claims 10
- 229940100994 interleukin-7 Drugs 0.000 claims 10
- 238000004519 manufacturing process Methods 0.000 claims 9
- 239000013604 expression vector Substances 0.000 claims 7
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 230000003834 intracellular effect Effects 0.000 claims 3
- 239000013598 vector Substances 0.000 claims 3
- 229920001184 polypeptide Polymers 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 102100022005 B-lymphocyte antigen CD20 Human genes 0.000 claims 1
- 101000897405 Homo sapiens B-lymphocyte antigen CD20 Proteins 0.000 claims 1
- 101000914514 Homo sapiens T-cell-specific surface glycoprotein CD28 Proteins 0.000 claims 1
- 102100027213 T-cell-specific surface glycoprotein CD28 Human genes 0.000 claims 1
- MHMNJMPURVTYEJ-UHFFFAOYSA-N fluorescein-5-isothiocyanate Chemical compound O1C(=O)C2=CC(N=C=S)=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 MHMNJMPURVTYEJ-UHFFFAOYSA-N 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 230000001177 retroviral effect Effects 0.000 claims 1
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021213604A JP7300763B2 (ja) | 2014-10-09 | 2021-12-28 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
| JP2023097065A JP7527049B2 (ja) | 2014-10-09 | 2023-06-13 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
| JP2024113188A JP7755890B2 (ja) | 2014-10-09 | 2024-07-16 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014208200 | 2014-10-09 | ||
| JP2014208200 | 2014-10-09 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017111736A Division JP6683990B2 (ja) | 2014-10-09 | 2017-06-06 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021213604A Division JP7300763B2 (ja) | 2014-10-09 | 2021-12-28 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020108398A JP2020108398A (ja) | 2020-07-16 |
| JP2020108398A5 true JP2020108398A5 (cg-RX-API-DMAC7.html) | 2021-02-12 |
| JP7008350B2 JP7008350B2 (ja) | 2022-02-10 |
Family
ID=55652864
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016552830A Active JP6161098B2 (ja) | 2014-10-09 | 2015-10-06 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
| JP2017111736A Active JP6683990B2 (ja) | 2014-10-09 | 2017-06-06 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
| JP2020048623A Active JP7008350B2 (ja) | 2014-10-09 | 2020-03-19 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
| JP2021213604A Active JP7300763B2 (ja) | 2014-10-09 | 2021-12-28 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
| JP2023097065A Active JP7527049B2 (ja) | 2014-10-09 | 2023-06-13 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
| JP2024113188A Active JP7755890B2 (ja) | 2014-10-09 | 2024-07-16 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016552830A Active JP6161098B2 (ja) | 2014-10-09 | 2015-10-06 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
| JP2017111736A Active JP6683990B2 (ja) | 2014-10-09 | 2017-06-06 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021213604A Active JP7300763B2 (ja) | 2014-10-09 | 2021-12-28 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
| JP2023097065A Active JP7527049B2 (ja) | 2014-10-09 | 2023-06-13 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
| JP2024113188A Active JP7755890B2 (ja) | 2014-10-09 | 2024-07-16 | Ｃａｒ発現ベクター及びｃａｒ発現ｔ細胞 |
Country Status (29)
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX358472B (es) * | 2014-10-09 | 2018-08-21 | Univ Yamaguchi | Vector de expresion de receptor de antigeno quimerico (car) y celulas t que expresan car. |
| GB201509413D0 (en) * | 2015-06-01 | 2015-07-15 | Ucl Business Plc | Fusion protein |
| EP3416686A1 (en) | 2016-02-16 | 2018-12-26 | Dana Farber Cancer Institute, Inc. | Immunotherapy compositions and methods |
| EP3431597A4 (en) | 2016-03-17 | 2019-11-13 | Yamaguchi University | IMMUNOCOMPETENT CELLS AND EXPRESSION VECTOR WITH EXPRESSION OF REGULATORY FACTORS OF IMMUNE FUNCTION |
| WO2018119518A1 (en) * | 2017-01-01 | 2018-07-05 | Lee Chi Yu Gregory | Rp215 chimeric antigen receptor construct and methods of making and using same |
| EP3569709A4 (en) * | 2017-01-10 | 2020-08-19 | Yamaguchi University | ANTI-GPC3 ANTIBODIES |
| RU2770002C2 (ru) | 2017-03-27 | 2022-04-14 | Нойл-Иммьюн Байотек, Инк. | Химерный антигенный рецептор |
| CN108484777B (zh) * | 2017-03-31 | 2022-07-12 | 李吉祐 | 人源化rp215单克隆抗体的嵌合抗原受体构建体及核酸分子与应用 |
| MX2020003737A (es) | 2017-10-10 | 2020-08-03 | Univ Yamaguchi | Potenciador para celulas t o celulas b que tienen funcion de memoria, inhibidor de recurrencia de tumor maligno, e inductor para inducir la funcion de memoria en celulas t o celulas b. |
| MX2020006666A (es) * | 2017-12-24 | 2020-08-31 | Noile Immune Biotech Inc | Celula inmunocompetente que expresa una molecula de superficie celular que reconoce especificamente la mesotelina humana, il-7 y ccl19. |
| CN118634318A (zh) * | 2017-12-27 | 2024-09-13 | 武田药品工业株式会社 | 含核酸脂质纳米粒子及其用途 |
| CN108641001A (zh) * | 2018-04-26 | 2018-10-12 | 上海怡豪生物科技有限公司 | 结肠癌的双靶点car-t治疗载体及其构建方法和应用 |
| CN108659133A (zh) * | 2018-04-26 | 2018-10-16 | 上海怡豪生物科技有限公司 | 肺癌的双靶点car-t治疗载体及其构建方法和应用 |
| CN108641000A (zh) * | 2018-04-26 | 2018-10-12 | 上海怡豪生物科技有限公司 | 肝癌的双靶点car-t治疗载体及其构建方法和应用 |
| SG11202011392VA (en) * | 2018-05-15 | 2020-12-30 | Carsgen Therapeutics Co Ltd | Genetically engineered cell and application thereof |
| KR20190141511A (ko) * | 2018-06-14 | 2019-12-24 | 주식회사 녹십자랩셀 | 신규 펩티드, 이를 포함하는 키메라 항원 수용체 및 이를 발현하는 면역 세포 |
| CN108866004A (zh) * | 2018-06-26 | 2018-11-23 | 奥妙生物技术（广州）有限公司 | Shp-1敲除的t细胞及其构建方法 |
| CN112399852A (zh) | 2018-06-28 | 2021-02-23 | 达纳-法伯癌症研究所有限公司 | 固体和液体恶性肿瘤中多重抗原受体t细胞对多种抗原的靶向 |
| US20230071098A1 (en) * | 2018-07-17 | 2023-03-09 | Noile-Immune Biotech, Inc. | Anti-gpc3 single-chain antibody-containing car |
| CN109055430A (zh) * | 2018-08-14 | 2018-12-21 | 杭州荣泽生物科技有限公司 | 一种共表达il18和ccl19蛋白及靶向muc1基因car-t细胞的制备方法 |
| SG11202101930XA (en) * | 2018-08-31 | 2021-03-30 | Noile Immune Biotech Inc | Car-expressing t cells and car expression vector |
| AU2019336031B2 (en) * | 2018-09-05 | 2024-07-11 | Act Therapeutics Inc. | Chimeric antigen receptor for solid cancer and T cells expressing chimeric antigen receptor |
| CN112771167B (zh) * | 2018-09-20 | 2025-09-26 | 克莱格医学有限公司 | 表达有趋化因子的细胞及用途 |
| WO2020077356A1 (en) * | 2018-10-12 | 2020-04-16 | Icell Gene Therapeutics Llc | CHIMERIC ANTIGEN RECEPTORS (CARs) COMPOSITIONS AND METHODS OF USE THEREOF |
| CN109504660B (zh) * | 2018-11-02 | 2021-08-06 | 温州启星生物技术有限公司 | 一种第四代car-t细胞及其构建方法和应用 |
| JP7630832B2 (ja) * | 2018-11-19 | 2025-02-18 | ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム | Ｃａｒおよびｔｃｒ形質導入用のモジュール式ポリシストロニックベクター |
| US20220145325A1 (en) * | 2019-03-08 | 2022-05-12 | Autolus Limited | Compositions and methods comprising engineered chimeric antigen receptor and modulator of car |
| EP3964568A4 (en) * | 2019-04-04 | 2023-01-11 | Shanghai Pharmaceuticals Holding Co., Ltd. | IMMUNE CELL CONTAINING A TUMOR ANTIGEN RECOGNITION RECEPTOR AND THEIR APPLICATION |
| CN112080525A (zh) * | 2019-06-14 | 2020-12-15 | 南京艾德免疫治疗研究院有限公司 | 一种改良型嵌合抗原受体t细胞的制备 |
| CN112080526A (zh) * | 2019-06-14 | 2020-12-15 | 南京艾德免疫治疗研究院有限公司 | 表达il-7和car的表达载体及免疫细胞 |
| JP7769325B2 (ja) * | 2019-07-23 | 2025-11-13 | 株式会社東芝 | Ｃａｒ－ｔ細胞の製造方法、核酸導入キャリア及びキット |
| CA3156231A1 (en) | 2019-10-28 | 2021-05-06 | Koji Tamada | Drug for treating cancer, combination drug, drug composition, immune responsive cell, nucleic acid delivery vehicle, and product |
| CN110922490B (zh) * | 2019-12-05 | 2023-03-03 | 浙江启新生物技术有限公司 | 分泌白介素7和趋化因子21的car表达载体及应用 |
| WO2021162521A1 (ko) * | 2020-02-14 | 2021-08-19 | (주)이뮤노텍바이오팜코리아 | 외부에서 도입된 세포 신호 조절 인자를 과발현하는 면역 세포 및 이들의 용도 |
| JP2021142156A (ja) * | 2020-03-12 | 2021-09-24 | 株式会社三洋物産 | 遊技機 |
| JP2021142159A (ja) * | 2020-03-12 | 2021-09-24 | 株式会社三洋物産 | 遊技機 |
| JP2021142158A (ja) * | 2020-03-12 | 2021-09-24 | 株式会社三洋物産 | 遊技機 |
| CN113528483B (zh) * | 2020-04-22 | 2024-08-16 | 复星凯特生物科技有限公司 | Shp2特异性失活突变蛋白及其在car-t治疗中应用 |
| GB202006820D0 (en) * | 2020-05-07 | 2020-06-24 | Autolus Ltd | Cell |
| CN115885038A (zh) | 2020-06-17 | 2023-03-31 | 国立大学法人京都大学 | 表达嵌合抗原受体的免疫活性细胞 |
| KR102297396B1 (ko) | 2020-07-29 | 2021-09-06 | (주)티카로스 | 면역시냅스를 안정화시키는 키메라 항원 수용체(car) t 세포 |
| CN116782937A (zh) | 2020-12-10 | 2023-09-19 | 优特力克斯有限公司 | 抗pd-1抗体及其用途 |
| CN114717203B (zh) * | 2020-12-22 | 2023-06-27 | 广东东阳光药业有限公司 | 一种hIL7/hCCL19双基因重组溶瘤病毒及其制备方法和用途 |
| CN114716548B (zh) | 2021-01-05 | 2024-11-05 | (株)爱恩德生物 | 抗-fgfr3抗体及其用途 |
| CN112961248B (zh) * | 2021-02-22 | 2022-03-18 | 广州百暨基因科技有限公司 | 共表达IL-7和CCR2b的嵌合抗原受体融合蛋白及其应用 |
| WO2022245098A1 (ko) | 2021-05-18 | 2022-11-24 | 주식회사 바이오솔루션 | 세포외소포체 분비능이 증진된 면역세포 및 이를 활용한 면역 항암요법 |
| TW202321287A (zh) | 2021-07-29 | 2023-06-01 | 日商武田藥品工業股份有限公司 | 特異性靶向間皮素之經工程改造之免疫細胞及其用途 |
| CN113913385A (zh) * | 2021-09-01 | 2022-01-11 | 苏州璞惠卓越生物科技有限公司 | 一种抑制蛋白阻断型嵌合抗原受体修饰的免疫细胞及其用途 |
| CN113921082B (zh) * | 2021-10-27 | 2023-04-07 | 云舟生物科技(广州)股份有限公司 | 基因搜索权重调整方法、计算机存储介质及电子设备 |
| WO2023081455A2 (en) * | 2021-11-08 | 2023-05-11 | Memorial Sloan-Kettering Cancer Center | Immune cells expressing glucose transporter 5 (gluts) and compositions and methods including the same |
| CN119234037A (zh) * | 2022-05-20 | 2024-12-31 | 武田药品工业株式会社 | 生产工程化免疫细胞的方法 |
| US12006353B2 (en) | 2022-07-25 | 2024-06-11 | Long Chen | Application of SCFV protein, car gene expression vector, CAR-T cell and application thereof |
| WO2024025343A1 (ko) | 2022-07-26 | 2024-02-01 | (주)에임드바이오 | 항-ror1 항체 및 이의 용도 |
| CN115505601B (zh) * | 2022-10-17 | 2024-05-28 | 深圳市先康达生命科学有限公司 | 一种两级SynNotch逻辑调控结构及其应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5857318A (ja) * | 1981-10-01 | 1983-04-05 | Nippon Koutai Kenkyusho:Kk | 癌細胞障害性リンパ球の製造法 |
| EP1334188B1 (en) | 2000-11-07 | 2006-08-30 | City of Hope | Cd19-specific redirected immune cells |
| KR20050118057A (ko) * | 2004-04-24 | 2005-12-15 | 김상희 | 아세틸디아실글리세롤류의 화합물을 유효성분으로함유하는 항암제 및 건강식품 |
| TWI436775B (zh) * | 2007-08-24 | 2014-05-11 | Oncotherapy Science Inc | 以抗原胜肽合併化療藥劑治療胰臟癌 |
| RU2573912C2 (ru) | 2008-10-08 | 2016-01-27 | Интрексон Корпорейшн | Сконструированные клетки, экспрессирующие множественные иммуномодуляторы, и их применения |
| PH12013501201A1 (en) | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| CA2821080C (en) | 2010-12-14 | 2021-02-02 | University Of Maryland, Baltimore | Universal anti-tag chimeric antigen receptor-expressing t cells and methods of treating cancer |
| TR201815488T4 (tr) | 2011-04-08 | 2018-11-21 | Health | Anti-epidermal büyüme faktör reseptörü varyant III kimerik antijen reseptörleri ve kanser tedavisi için kullanımı. |
| US20130071414A1 (en) * | 2011-04-27 | 2013-03-21 | Gianpietro Dotti | Engineered cd19-specific t lymphocytes that coexpress il-15 and an inducible caspase-9 based suicide gene for the treatment of b-cell malignancies |
| EP3326467B1 (en) * | 2011-09-16 | 2020-03-11 | Baylor College of Medicine | Targeting the tumor microenvironment using manipulated nkt cells |
| KR101956751B1 (ko) | 2011-10-07 | 2019-03-11 | 고쿠리츠다이가쿠호진 미에다이가쿠 | 키메라 항원 수용체 |
| JP6850528B2 (ja) | 2012-02-13 | 2021-03-31 | シアトル チルドレンズ ホスピタル ドゥーイング ビジネス アズ シアトル チルドレンズ リサーチ インスティテュート | 二重特異性キメラ抗原受容体およびその治療的使用 |
| CN102625373A (zh) | 2012-02-22 | 2012-08-01 | 中兴通讯股份有限公司 | 一种智能载波管理方法及装置 |
| JP2015509716A (ja) * | 2012-02-22 | 2015-04-02 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 第二世代キメラ抗原受容体におけるｃｄ２シグナル伝達ドメインの使用 |
| MX358472B (es) * | 2014-10-09 | 2018-08-21 | Univ Yamaguchi | Vector de expresion de receptor de antigeno quimerico (car) y celulas t que expresan car. |
-
2015
- 2015-10-06 MX MX2017004393A patent/MX358472B/es active IP Right Grant
- 2015-10-06 HR HRP20191839TT patent/HRP20191839T1/hr unknown
- 2015-10-06 RS RSP20191315 patent/RS59441B1/sr unknown
- 2015-10-06 PT PT158494161T patent/PT3205720T/pt unknown
- 2015-10-06 SI SI201531887T patent/SI3597742T1/sl unknown
- 2015-10-06 US US15/513,870 patent/US10316102B2/en active Active
- 2015-10-06 EP EP19196196.0A patent/EP3597742B1/en active Active
- 2015-10-06 SM SM20190663T patent/SMT201900663T1/it unknown
- 2015-10-06 DK DK15849416.1T patent/DK3205720T3/da active
- 2015-10-06 KR KR1020177009895A patent/KR101890638B1/ko active Active
- 2015-10-06 EP EP15849416.1A patent/EP3205720B1/en active Active
- 2015-10-06 BR BR112017006710A patent/BR112017006710B1/pt active IP Right Grant
- 2015-10-06 SI SI201530950T patent/SI3205720T1/sl unknown
- 2015-10-06 JP JP2016552830A patent/JP6161098B2/ja active Active
- 2015-10-06 CN CN201580053922.1A patent/CN107109421B/zh active Active
- 2015-10-06 ES ES15849416T patent/ES2751945T3/es active Active
- 2015-10-06 AU AU2015329444A patent/AU2015329444B2/en active Active
- 2015-10-06 ES ES19196196T patent/ES2927366T3/es active Active
- 2015-10-06 PT PT191961960T patent/PT3597742T/pt unknown
- 2015-10-06 MY MYPI2017701137A patent/MY167722A/en unknown
- 2015-10-06 RU RU2017114545A patent/RU2670147C1/ru active
- 2015-10-06 LT LT15849416T patent/LT3205720T/lt unknown
- 2015-10-06 HU HUE19196196A patent/HUE060047T2/hu unknown
- 2015-10-06 PL PL19196196.0T patent/PL3597742T3/pl unknown
- 2015-10-06 RS RS20220895A patent/RS63601B1/sr unknown
- 2015-10-06 CA CA2962375A patent/CA2962375C/en active Active
- 2015-10-06 HU HUE15849416A patent/HUE046710T2/hu unknown
- 2015-10-06 WO PCT/JP2015/005080 patent/WO2016056228A1/ja not_active Ceased
- 2015-10-06 NZ NZ730382A patent/NZ730382A/en unknown
- 2015-10-06 SG SG11201702391RA patent/SG11201702391RA/en unknown
- 2015-10-06 HR HRP20221211TT patent/HRP20221211T1/hr unknown
- 2015-10-06 DK DK19196196.0T patent/DK3597742T3/da active
- 2015-10-06 PL PL15849416T patent/PL3205720T3/pl unknown
- 2015-10-06 LT LTEP19196196.0T patent/LT3597742T/lt unknown
- 2015-10-08 TW TW104133272A patent/TWI688651B/zh active
-
2017
- 2017-03-22 ZA ZA2017/01968A patent/ZA201701968B/en unknown
- 2017-03-31 PH PH12017500596A patent/PH12017500596B1/en unknown
- 2017-04-02 IL IL251504A patent/IL251504B/en active IP Right Grant
- 2017-06-06 JP JP2017111736A patent/JP6683990B2/ja active Active
-
2019
- 2019-05-06 US US16/404,165 patent/US10906984B2/en active Active
- 2019-11-26 CY CY20191101239T patent/CY1122324T1/el unknown
-
2020
- 2020-03-19 JP JP2020048623A patent/JP7008350B2/ja active Active
- 2020-12-23 US US17/133,286 patent/US20210253726A1/en not_active Abandoned
-
2021
- 2021-12-28 JP JP2021213604A patent/JP7300763B2/ja active Active
-
2023
- 2023-06-13 JP JP2023097065A patent/JP7527049B2/ja active Active
-
2024
- 2024-07-16 JP JP2024113188A patent/JP7755890B2/ja active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020108398A5 (cg-RX-API-DMAC7.html) | ||
| JP2023116674A5 (cg-RX-API-DMAC7.html) | ||
| JP7115982B2 (ja) | 癌の治療のための組成物及び方法 | |
| Fujiwara et al. | Impact of scFv structure in chimeric antigen receptor on receptor expression efficiency and antigen recognition properties | |
| Felices et al. | Generation of BiKEs and TriKEs to improve NK cell-mediated targeting of tumor cells | |
| JP2018504459A5 (cg-RX-API-DMAC7.html) | ||
| JP2021177771A5 (cg-RX-API-DMAC7.html) | ||
| JP2019150066A5 (cg-RX-API-DMAC7.html) | ||
| JP2018526033A5 (cg-RX-API-DMAC7.html) | ||
| JP2019535262A5 (cg-RX-API-DMAC7.html) | ||
| JP2018521663A5 (cg-RX-API-DMAC7.html) | ||
| JP2019528077A5 (cg-RX-API-DMAC7.html) | ||
| CN107880128B (zh) | 一种抗cd19的全人源抗体或抗体片段及其方法和应用 | |
| JP2018504143A5 (cg-RX-API-DMAC7.html) | ||
| JPWO2019173324A5 (cg-RX-API-DMAC7.html) | ||
| JP2018528786A5 (cg-RX-API-DMAC7.html) | ||
| JP2019527041A5 (cg-RX-API-DMAC7.html) | ||
| AU2017205197A1 (en) | Conditionally active heterodimeric polypeptides and methods of use thereof | |
| JP2018518990A5 (cg-RX-API-DMAC7.html) | ||
| US20210393691A1 (en) | Process for producing genetically engineered t cells | |
| CN110637033A (zh) | 用于治疗癌症的组合物和方法 | |
| CA3075619A1 (en) | Methods and systems for performing a patient-specific immunotherapy procedure with chain-of-custody and chain-of-identity biological sample tracking | |
| JP2019514361A5 (cg-RX-API-DMAC7.html) | ||
| NZ759969A (en) | Tagged chimeric effector molecules and receptors thereof | |
| HRP20160857T1 (hr) | Bispecifična jednolančana protutijela, specifična za visokomolekulske ciljne antigene |