JP2020019761A5 - - Google Patents

Info

Publication number

JP2020019761A5

JP2020019761A5 JP2019036083A JP2019036083A JP2020019761A5 JP 2020019761 A5 JP2020019761 A5 JP 2020019761A5 JP 2019036083 A JP2019036083 A JP 2019036083A JP 2019036083 A JP2019036083 A JP 2019036083A JP 2020019761 A5 JP2020019761 A5 JP 2020019761A5

Authority

JP

Japan

Prior art keywords

film

saponin

surfactant

weight

polymer component

Prior art date

2019-02-28

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

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• -1 fatty acid esters Chemical class 0.000 claims 23
• 229930182490 saponin Natural products 0.000 claims 17
• 150000007949 saponins Chemical class 0.000 claims 17
• 235000017709 saponins Nutrition 0.000 claims 17
• 239000001397 quillaja saponaria molina bark Substances 0.000 claims 15
• LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims 14
• 239000004094 surface-active agent Substances 0.000 claims 14
• 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 11
• 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 11
• UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical group OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 11
• 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 11
• 229920000642 polymer Polymers 0.000 claims 10
• 235000014113 dietary fatty acids Nutrition 0.000 claims 8
• 239000000194 fatty acid Substances 0.000 claims 8
• 229930195729 fatty acid Natural products 0.000 claims 8
• 229920001451 polypropylene glycol Chemical class 0.000 claims 8
• 229920003171 Poly (ethylene oxide) Polymers 0.000 claims 7
• WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims 7
• 150000003839 salts Chemical class 0.000 claims 6
• 239000002775 capsule Substances 0.000 claims 5
• 108010010803 Gelatin Proteins 0.000 claims 4
• 229930006000 Sucrose Natural products 0.000 claims 4
• 239000002253 acid Substances 0.000 claims 4
• 150000002148 esters Chemical class 0.000 claims 4
• 229920000159 gelatin Polymers 0.000 claims 4
• 239000008273 gelatin Substances 0.000 claims 4
• 235000019322 gelatine Nutrition 0.000 claims 4
• 235000011852 gelatine desserts Nutrition 0.000 claims 4
• 239000005720 sucrose Substances 0.000 claims 4
• CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 3
• 239000003795 chemical substances by application Substances 0.000 claims 3
• 229920000233 poly(alkylene oxides) Chemical class 0.000 claims 3
• 150000005846 sugar alcohols Polymers 0.000 claims 3
• 230000002087 whitening effect Effects 0.000 claims 3
• 235000016068 Berberis vulgaris Nutrition 0.000 claims 2
• 241000335053 Beta vulgaris Species 0.000 claims 2
• 244000068988 Glycine max Species 0.000 claims 2
• 235000010469 Glycine max Nutrition 0.000 claims 2
• UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims 2
• 235000010586 Sophora japonica Nutrition 0.000 claims 2
• 244000046101 Sophora japonica Species 0.000 claims 2
• 150000008051 alkyl sulfates Chemical class 0.000 claims 2
• 238000000034 method Methods 0.000 claims 2
• 239000000049 pigment Substances 0.000 claims 2
• BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 claims 2
• 229930185549 teaseedsaponin Natural products 0.000 claims 2
• JNYAEWCLZODPBN-JGWLITMVSA-N (2r,3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical compound OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O JNYAEWCLZODPBN-JGWLITMVSA-N 0.000 claims 1
• 244000000626 Daucus carota Species 0.000 claims 1
• 235000002767 Daucus carota Nutrition 0.000 claims 1
• 239000005977 Ethylene Substances 0.000 claims 1
• PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerol Natural products OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 1
• 244000131316 Panax pseudoginseng Species 0.000 claims 1
• 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims 1
• 235000003140 Panax quinquefolius Nutrition 0.000 claims 1
• 239000004373 Pullulan Substances 0.000 claims 1
• 229920001218 Pullulan Polymers 0.000 claims 1
• ZPVGIKNDGJGLCO-VGAMQAOUSA-N [(2s,3r,4s,5s,6r)-2-[(2s,3s,4s,5r)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)O[C@@]1([C@]2(CO)[C@H]([C@H](O)[C@@H](CO)O2)O)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O ZPVGIKNDGJGLCO-VGAMQAOUSA-N 0.000 claims 1
• 150000005215 alkyl ethers Chemical class 0.000 claims 1
• 150000003863 ammonium salts Chemical class 0.000 claims 1
• 230000015572 biosynthetic process Effects 0.000 claims 1
• 229920002678 cellulose Polymers 0.000 claims 1
• 239000001913 cellulose Substances 0.000 claims 1
• 239000011248 coating agent Substances 0.000 claims 1
• 238000000576 coating method Methods 0.000 claims 1
• 239000002537 cosmetic Substances 0.000 claims 1
• ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 claims 1
• WPUMTJGUQUYPIV-JIZZDEOASA-L disodium (S)-malate Chemical compound [Na+].[Na+].[O-]C(=O)[C@@H](O)CC([O-])=O WPUMTJGUQUYPIV-JIZZDEOASA-L 0.000 claims 1
• BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1
• 235000008434 ginseng Nutrition 0.000 claims 1
• 235000011187 glycerol Nutrition 0.000 claims 1
• 235000013402 health food Nutrition 0.000 claims 1
• 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• 239000000203 mixture Substances 0.000 claims 1
• 229910000402 monopotassium phosphate Inorganic materials 0.000 claims 1
• 235000019796 monopotassium phosphate Nutrition 0.000 claims 1
• 229910000403 monosodium phosphate Inorganic materials 0.000 claims 1
• 235000019799 monosodium phosphate Nutrition 0.000 claims 1
• PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 claims 1
• 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims 1
• 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims 1
• 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 claims 1
• 229920000053 polysorbate 80 Polymers 0.000 claims 1
• 229940068968 polysorbate 80 Drugs 0.000 claims 1
• XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims 1
• 229910000027 potassium carbonate Inorganic materials 0.000 claims 1
• 235000011181 potassium carbonates Nutrition 0.000 claims 1
• 235000019423 pullulan Nutrition 0.000 claims 1
• 235000019265 sodium DL-malate Nutrition 0.000 claims 1
• 229910000030 sodium bicarbonate Inorganic materials 0.000 claims 1
• 235000017557 sodium bicarbonate Nutrition 0.000 claims 1
• 239000001509 sodium citrate Substances 0.000 claims 1
• NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 1
• 229960001790 sodium citrate Drugs 0.000 claims 1
• 235000011083 sodium citrates Nutrition 0.000 claims 1
• AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 claims 1
• FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 claims 1
• 239000001394 sodium malate Substances 0.000 claims 1
• 235000019830 sodium polyphosphate Nutrition 0.000 claims 1
• 229940048086 sodium pyrophosphate Drugs 0.000 claims 1
• 159000000000 sodium salts Chemical class 0.000 claims 1
• 229940074404 sodium succinate Drugs 0.000 claims 1
• ZDQYSKICYIVCPN-UHFFFAOYSA-L sodium succinate (anhydrous) Chemical compound [Na+].[Na+].[O-]C(=O)CCC([O-])=O ZDQYSKICYIVCPN-UHFFFAOYSA-L 0.000 claims 1
• 150000005856 steroid saponins Chemical class 0.000 claims 1
• 235000019818 tetrasodium diphosphate Nutrition 0.000 claims 1
• 239000001577 tetrasodium phosphonato phosphate Substances 0.000 claims 1
• 150000008130 triterpenoid saponins Chemical class 0.000 claims 1
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
• 239000012463 white pigment Substances 0.000 claims 1