|
US5549910A
(en)
|
1989-03-31 |
1996-08-27 |
The Regents Of The University Of California |
Preparation of liposome and lipid complex compositions
|
|
US5252334A
(en)
|
1989-09-08 |
1993-10-12 |
Cygnus Therapeutic Systems |
Solid matrix system for transdermal drug delivery
|
|
JP3218637B2
(ja)
|
1990-07-26 |
2001-10-15 |
大正製薬株式会社 |
安定なリポソーム水懸濁液
|
|
JP2958076B2
(ja)
|
1990-08-27 |
1999-10-06 |
株式会社ビタミン研究所 |
遺伝子導入用多重膜リポソーム及び遺伝子捕捉多重膜リポソーム製剤並びにその製法
|
|
US5399363A
(en)
|
1991-01-25 |
1995-03-21 |
Eastman Kodak Company |
Surface modified anticancer nanoparticles
|
|
US5478745A
(en)
|
1992-12-04 |
1995-12-26 |
University Of Pittsburgh |
Recombinant viral vector system
|
|
US5543158A
(en)
|
1993-07-23 |
1996-08-06 |
Massachusetts Institute Of Technology |
Biodegradable injectable nanoparticles
|
|
US5741516A
(en)
|
1994-06-20 |
1998-04-21 |
Inex Pharmaceuticals Corporation |
Sphingosomes for enhanced drug delivery
|
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
|
US5856152A
(en)
|
1994-10-28 |
1999-01-05 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV vector and methods of use therefor
|
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
US5697899A
(en)
|
1995-02-07 |
1997-12-16 |
Gensia |
Feedback controlled drug delivery system
|
|
IE80468B1
(en)
|
1995-04-04 |
1998-07-29 |
Elan Corp Plc |
Controlled release biodegradable nanoparticles containing insulin
|
|
US5738868A
(en)
|
1995-07-18 |
1998-04-14 |
Lipogenics Ltd. |
Liposome compositions and kits therefor
|
|
US6001650A
(en)
|
1995-08-03 |
1999-12-14 |
Avigen, Inc. |
High-efficiency wild-type-free AAV helper functions
|
|
US5656016A
(en)
|
1996-03-18 |
1997-08-12 |
Abbott Laboratories |
Sonophoretic drug delivery system
|
|
US5797898A
(en)
|
1996-07-02 |
1998-08-25 |
Massachusetts Institute Of Technology |
Microchip drug delivery devices
|
|
US5783208A
(en)
|
1996-07-19 |
1998-07-21 |
Theratech, Inc. |
Transdermal drug delivery matrix for coadministering estradiol and another steroid
|
|
US5779708A
(en)
|
1996-08-15 |
1998-07-14 |
Cyberdent, Inc. |
Intraosseous drug delivery device and method
|
|
EP0931158A1
(en)
|
1996-09-06 |
1999-07-28 |
The Trustees Of The University Of Pennsylvania |
An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase
|
|
US6177403B1
(en)
|
1996-10-21 |
2001-01-23 |
The Trustees Of The University Of Pennsylvania |
Compositions, methods, and apparatus for delivery of a macromolecular assembly to an extravascular tissue of an animal
|
|
US6544523B1
(en)
|
1996-11-13 |
2003-04-08 |
Chiron Corporation |
Mutant forms of Fas ligand and uses thereof
|
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
US6251677B1
(en)
|
1997-08-25 |
2001-06-26 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV virus and methods of use thereof
|
|
US6346415B1
(en)
|
1997-10-21 |
2002-02-12 |
Targeted Genetics Corporation |
Transcriptionally-activated AAV inverted terminal repeats (ITRS) for use with recombinant AAV vectors
|
|
US6953690B1
(en)
|
1998-03-20 |
2005-10-11 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
DE69939169D1
(de)
|
1998-05-28 |
2008-09-04 |
Us Gov Health & Human Serv |
Aav5 vektoren und deren verwendung
|
|
US20030110526A1
(en)
|
1998-08-25 |
2003-06-12 |
Robert H. Brown |
Dysferlin mutations
|
|
JP4693244B2
(ja)
|
1999-03-18 |
2011-06-01 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスのヘルパー無しの生産のための組成物および方法
|
|
US6498244B1
(en)
|
1999-05-28 |
2002-12-24 |
Cell Genesys, Inc. |
Adeno-associated virus capsid immunologic determinants
|
|
AU7895700A
(en)
|
1999-10-15 |
2001-04-30 |
Dalhousie University |
Method and vector for producing and transferring trans-spliced peptides
|
|
US7638120B2
(en)
|
2000-03-14 |
2009-12-29 |
Thomas Jefferson University |
High transgene expression of a pseudotyped adeno-associated virus type
|
|
US7749492B2
(en)
|
2001-01-05 |
2010-07-06 |
Nationwide Children's Hospital, Inc. |
AAV vectors and methods
|
|
WO2002053703A2
(en)
|
2001-01-05 |
2002-07-11 |
Children's Hospital, Inc. |
Aav2 vectors and methods
|
|
WO2003004660A1
(en)
|
2001-07-03 |
2003-01-16 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Methods of administering vectors to synaptically connected neurons
|
|
IL159756A0
(en)
*
|
2001-07-12 |
2004-06-20 |
Univ Massachusetts |
IN VIVO PRODUCTION OF SMALL INTERFERING RNAs THAT MEDIATE GENE SILENCING
|
|
EP1419245A4
(en)
|
2001-07-13 |
2006-04-05 |
Univ Iowa Res Found |
ADENO-ASSOCIATED PSEUDOTYPE VIRUSES AND USES THEREOF
|
|
US20030109476A1
(en)
*
|
2001-08-07 |
2003-06-12 |
Kmiec Eric B. |
Compositions and methods for the prevention and treatment of Huntington's disease
|
|
CN103555677B
(zh)
|
2001-11-13 |
2018-01-30 |
宾夕法尼亚大学托管会 |
检测和/或鉴定腺伴随病毒(aav)序列以及分离所鉴定的新型序列的方法
|
|
PT2573170T
(pt)
|
2001-12-17 |
2018-03-26 |
Univ Pennsylvania |
Sequências de um vírus adenoassociado (aav) de serotipo 9, vetor contendo as mesmas, e suas utilizações
|
|
US20050137153A1
(en)
|
2002-02-20 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of alpha-1 antitrypsin (AAT) gene expression using short interfering nucleic acid (siNA)
|
|
WO2003089612A2
(en)
|
2002-04-17 |
2003-10-30 |
University Of Florida Research Foundation, Inc. |
IMPROVED rAAV VECTORS
|
|
US20070003518A1
(en)
|
2002-04-19 |
2007-01-04 |
Atkinson Mark A |
Raav vector-based compositions and methods for the prevention and treatment of mammalian diseases
|
|
CA2426283C
(en)
|
2002-04-29 |
2006-06-27 |
The Trustees Of The University Of Pennsylvania |
Method for direct rescue and amplification of integrated viruses from cellular dna of tissues
|
|
US20060093589A1
(en)
|
2004-02-19 |
2006-05-04 |
Warrington Kenneth H |
Vp2-modified raav vector compositions and uses therefor
|
|
US20080274989A1
(en)
|
2002-08-05 |
2008-11-06 |
University Of Iowa Research Foundation |
Rna Interference Suppression of Neurodegenerative Diseases and Methods of Use Thereof
|
|
US20050106731A1
(en)
*
|
2002-08-05 |
2005-05-19 |
Davidson Beverly L. |
siRNA-mediated gene silencing with viral vectors
|
|
US20050255086A1
(en)
|
2002-08-05 |
2005-11-17 |
Davidson Beverly L |
Nucleic acid silencing of Huntington's Disease gene
|
|
WO2004067753A2
(en)
|
2003-01-28 |
2004-08-12 |
Cellectis |
Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof.
|
|
US20040219528A1
(en)
|
2003-04-15 |
2004-11-04 |
Morris David W. |
Novel therapeutic targets in cancer
|
|
US7387896B2
(en)
|
2003-03-26 |
2008-06-17 |
The Regents Of The University Of Michigan |
MicroRNA vectors
|
|
US20060228800A1
(en)
|
2003-05-15 |
2006-10-12 |
Shi-Lung Lin |
Novel Transgenic Methods Using intronic RNA
|
|
US7459547B2
(en)
|
2003-06-02 |
2008-12-02 |
University Of Massachusetts |
Methods and compositions for controlling efficacy of RNA silencing
|
|
WO2008005562A2
(en)
*
|
2006-07-07 |
2008-01-10 |
University Of Massachusetts |
Rna silencing compositions and methods for the treatment of huntington's disease
|
|
US8680063B2
(en)
*
|
2003-09-12 |
2014-03-25 |
University Of Massachusetts |
RNA interference for the treatment of gain-of-function disorders
|
|
DK3211085T3
(da)
*
|
2003-09-30 |
2021-06-21 |
Univ Pennsylvania |
Klader af adeno-associeret virus (aav), sekvenser, vektorer indeholdende disse og anvendelser deraf
|
|
WO2005087926A2
(en)
|
2004-03-05 |
2005-09-22 |
Benitec, Inc. |
Multiple promoter expression cassettes for simultaneous delivery of rnai agents
|
|
WO2005096781A2
(en)
|
2004-04-06 |
2005-10-20 |
University Of Massachusetts |
Methods and compositions for treating gain-of-function disorders using rna interference
|
|
WO2005116224A2
(en)
|
2004-05-18 |
2005-12-08 |
Children's Memorial Hospital |
Tetracycline-regulated adeno-associated viral (aav) vectors for gene delivery to the nervous system
|
|
US7427396B2
(en)
|
2004-06-03 |
2008-09-23 |
Genzyme Corporation |
AAV vectors for gene delivery to the lung
|
|
US7892809B2
(en)
|
2004-12-15 |
2011-02-22 |
The University Of North Carolina At Chapel Hill |
Chimeric vectors
|
|
EP1877556B1
(en)
|
2005-03-25 |
2011-09-14 |
Medtronic, Inc. |
Use of anti-tnf or anti-il1 rnai to suppress pro- inflammatory cytokine actions locally to treat pain
|
|
US8999678B2
(en)
|
2005-04-07 |
2015-04-07 |
The Trustees Of The University Of Pennsylvania |
Method of increasing the function of an AAV vector
|
|
WO2006119432A2
(en)
|
2005-04-29 |
2006-11-09 |
The Government Of The U.S.A., As Rep. By The Sec., Dept. Of Health & Human Services |
Isolation, cloning and characterization of new adeno-associated virus (aav) serotypes
|
|
SG162726A1
(en)
|
2005-05-27 |
2010-07-29 |
San Raffaele Centro Fond |
Gene vector comprising mi-rna
|
|
US20070213292A1
(en)
|
2005-08-10 |
2007-09-13 |
The Rockefeller University |
Chemically modified oligonucleotides for use in modulating micro RNA and uses thereof
|
|
JP5523705B2
(ja)
|
2005-08-29 |
2014-06-18 |
レグルス・セラピューティクス・インコーポレイテッド |
Mir−122aをモジュレートする使用方法
|
|
EP2487261B1
(en)
|
2006-01-05 |
2015-07-01 |
The Ohio State University Research Foundation |
MicroRNA-based methods and compositions for the diagnosis and treatment of solid cancers
|
|
JP5425474B2
(ja)
|
2006-01-26 |
2014-02-26 |
アイシス ファーマシューティカルズ, インコーポレーテッド |
ハンチンチン対する、組成物及びその使用
|
|
WO2008016391A2
(en)
|
2006-01-31 |
2008-02-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
Self-complementary parvoviral vectors, and methods for making and using the same
|
|
CA2642848C
(en)
|
2006-03-03 |
2016-07-12 |
Amorfix Life Sciences Ltd. |
Methods and compositions to treat and detect misfolded-sod1 mediated diseases
|
|
US7588772B2
(en)
|
2006-03-30 |
2009-09-15 |
Board Of Trustees Of The Leland Stamford Junior University |
AAV capsid library and AAV capsid proteins
|
|
US20080199961A1
(en)
*
|
2006-08-25 |
2008-08-21 |
Avi Biopharma, Inc. |
ANTISENSE COMPOSITION AND METHOD FOR INHIBITION OF miRNA BIOGENESIS
|
|
EP2799547B1
(en)
|
2006-11-08 |
2016-12-21 |
Veritas Bio, LLC |
In Vivo Delivery of RNA to a Target Cell
|
|
EP2623605B1
(en)
|
2007-04-09 |
2018-11-28 |
University of Florida Research Foundation, Inc. |
RAAV vector compositions having tyrosine-modified capsid proteins and methods for use
|
|
ES2907452T3
(es)
|
2007-04-12 |
2022-04-25 |
The Provost Fellows Found Scholars & The Other Members Of Board Of The College Of The Holy & Undiv T |
Supresión y reemplazo genético
|
|
WO2008137867A2
(en)
|
2007-05-03 |
2008-11-13 |
Rosetta Inpharmatics Llc |
Compositions comprising mir34 therapeutic agents for treating cancer
|
|
WO2008143786A1
(en)
*
|
2007-05-14 |
2008-11-27 |
The Rockefeller University |
Production of artificial micrornas using synthetic microrna precursors
|
|
WO2008147839A1
(en)
|
2007-05-23 |
2008-12-04 |
Dharmacon, Inc. |
Micro-rna scaffolds and non-naturally occurring micro-rnas
|
|
PT2164967E
(pt)
|
2007-05-31 |
2015-10-27 |
Univ Iowa Res Found |
Redução da toxicidade não dirigida do arn de interferência
|
|
EP2058401A1
(en)
|
2007-10-05 |
2009-05-13 |
Genethon |
Widespread gene delivery to motor neurons using peripheral injection of AAV vectors
|
|
WO2009079592A2
(en)
|
2007-12-17 |
2009-06-25 |
California Institute Of Technology |
Modulating immune system development and function through microrna mir-146
|
|
US20090215879A1
(en)
|
2008-02-26 |
2009-08-27 |
University Of North Carolina At Chapel Hill |
Methods and compositions for adeno-associated virus (aav) with hi loop mutations
|
|
WO2009109665A1
(en)
|
2008-03-07 |
2009-09-11 |
Santaris Pharma A/S |
Pharmaceutical compositions for treatment of microrna related diseases
|
|
WO2009146178A1
(en)
|
2008-04-15 |
2009-12-03 |
President And Fellows Of Harvard College |
Angiogenin and amyotrophic lateral sclerosis
|
|
US9217155B2
(en)
|
2008-05-28 |
2015-12-22 |
University Of Massachusetts |
Isolation of novel AAV'S and uses thereof
|
|
CA2726052A1
(en)
|
2008-06-04 |
2009-12-10 |
The Board Of Regents Of The University Of Texas System |
Modulation of gene expression through endogenous small rna targeting of gene promoters
|
|
US20110171262A1
(en)
|
2008-06-17 |
2011-07-14 |
Andrew Christian Bakker |
Parvoviral capsid with incorporated gly-ala repeat region
|
|
US20110172293A1
(en)
|
2008-07-08 |
2011-07-14 |
Fish Jason E |
Methods and Compositions for Modulating Angiogenesis
|
|
EP2329275A2
(en)
|
2008-09-04 |
2011-06-08 |
Galenea Corporation |
Synaptic vesicle cycling assays and systems
|
|
WO2010034314A1
(en)
|
2008-09-24 |
2010-04-01 |
Aarhus Universitet |
Retroviral delivery of synthectic gene cassettes
|
|
WO2010071454A1
(en)
|
2008-12-17 |
2010-06-24 |
Auckland Uniservices Limited |
Adeno-associated viral vectors and uses thereof
|
|
WO2010099383A2
(en)
|
2009-02-26 |
2010-09-02 |
The Johns Hopkins University |
Compositions and methods for ex vivo hepatic nucleic acid delivery
|
|
AU2010243276B2
(en)
*
|
2009-04-30 |
2016-09-15 |
Fondazione Telethon Ets |
Gene vector
|
|
SG10202109219SA
(en)
|
2009-05-02 |
2021-10-28 |
Genzyme Corp |
Gene therapy for neurodegenerative disorders
|
|
WO2010138263A2
(en)
|
2009-05-28 |
2010-12-02 |
University Of Massachusetts |
Novel aav 's and uses thereof
|
|
EP2261242A1
(en)
|
2009-06-10 |
2010-12-15 |
Universite Catholique De Louvain |
Aspartate-N-acetyltransferase enzyme, diagnostic method and therapeutic method
|
|
NZ599032A
(en)
*
|
2009-09-11 |
2014-09-26 |
Isis Pharmaceuticals Inc |
Modulation of huntingtin expression
|
|
US20120270930A1
(en)
|
2009-10-29 |
2012-10-25 |
Academisch Ziekenhuis Leiden H.O.D.N. Lumc |
Methods and compositions for dysferlin exon-skipping
|
|
RU2606012C2
(ru)
|
2009-11-09 |
2017-01-10 |
Дженепод Терапевтикс Аб |
Новая вирусная векторная конструкция для нейронспецифического оптимизированного непрерывного синтеза dopa in vivo
|
|
WO2011062298A1
(ja)
|
2009-11-19 |
2011-05-26 |
国立大学法人岡山大学 |
遺伝子発現を上昇させるシステム及び該システムを保持したベクター
|
|
US9169494B2
(en)
|
2010-01-12 |
2015-10-27 |
The University Of North Carolina At Chapel Hill |
Restrictive inverted terminal repeats for viral vectors
|
|
WO2011094198A1
(en)
|
2010-01-28 |
2011-08-04 |
The Children's Hospital Of Philadelphia Research Institute, Abramson Research Center |
A scalable manufacturing platform for viral vector purification and viral vectors so purified for use in gene therapy
|
|
AU2011223820B2
(en)
|
2010-03-01 |
2016-01-14 |
The Children's Hospital Of Philadelphia |
Nucleic acids for targeting multiple regions of the HCV genome
|
|
EP2561075B1
(en)
|
2010-04-23 |
2018-06-27 |
University of Massachusetts |
Aav-based treatment of cholesterol-related disorders
|
|
CA2833905C
(en)
|
2010-04-23 |
2019-09-10 |
University Of Massachusetts |
Multicistronic expression constructs
|
|
DK2826860T3
(en)
|
2010-04-23 |
2018-12-03 |
Univ Massachusetts |
CNS targeting AAV vectors and methods for their use
|
|
US8785413B2
(en)
|
2010-09-27 |
2014-07-22 |
Florida Atlantic University Research Corporation |
Materials and methods for the treatment of pathological neovascularization in the eye
|
|
ES2739804T3
(es)
|
2011-02-12 |
2020-02-04 |
Univ Iowa Res Found |
Compuestos terapéuticos
|
|
ES2724800T3
(es)
|
2011-02-17 |
2019-09-16 |
Univ Pennsylvania |
Composiciones y métodos para alterar la especificidad de tejido y mejorar la transferencia génica mediada por AAV9
|
|
EP2500434A1
(en)
|
2011-03-12 |
2012-09-19 |
Association Institut de Myologie |
Capsid-free AAV vectors, compositions, and methods for vector production and gene delivery
|
|
US20140147418A1
(en)
|
2011-04-15 |
2014-05-29 |
The Us Of America, As Represented By The Secretary Department Of Health And Human Services |
Aav mediated ctla-4 gene transfer to treat sjogren's syndrome
|
|
EP3318634A1
(en)
|
2011-04-21 |
2018-05-09 |
University of Massachusetts |
Raav-based compositions and methods for treating diseases involving dominant-negative or gain of function mutations
|
|
US8609088B2
(en)
|
2011-05-10 |
2013-12-17 |
Regents Of The University Of Minnesota |
Intranasal delivery of therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases
|
|
US10184151B2
(en)
|
2011-10-11 |
2019-01-22 |
The Brigham And Women's Hospital, Inc. |
Micrornas in neurodegenerative disorders
|
|
US20130142861A1
(en)
|
2011-12-05 |
2013-06-06 |
National Yang Ming University |
Compositions And Method For Detecting And Treating Abnormal Liver Homeostasis And Hepatocarcinogenesis
|
|
WO2013123503A1
(en)
|
2012-02-17 |
2013-08-22 |
The Children's Hospital Of Philadelphia |
Aav vector compositions and methods for gene transfer to cells, organs and tissues
|
|
WO2013170078A1
(en)
|
2012-05-09 |
2013-11-14 |
Oregon Health & Science University |
Adeno associated virus plasmids and vectors
|
|
WO2013190059A1
(en)
|
2012-06-21 |
2013-12-27 |
Association Institut De Myologie |
Widespread gene delivery of gene therapy vectors
|
|
US20140066595A1
(en)
*
|
2012-09-04 |
2014-03-06 |
Thermo Fisher Scientific Biosciences Inc. |
Modulators of Protein Production in a Human Cell Line and Cell-free Extracts Produced Therefrom
|
|
WO2014093622A2
(en)
|
2012-12-12 |
2014-06-19 |
The Broad Institute, Inc. |
Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
|
|
JP2016507228A
(ja)
|
2013-01-14 |
2016-03-10 |
リコンビネティクス・インコーポレイテッドRecombinetics,Inc. |
無角家畜
|
|
EP2970946A4
(en)
|
2013-03-13 |
2016-09-07 |
Philadelphia Children Hospital |
ADENOASSOZED VIRUS VECTORS AND METHOD FOR USE THEREOF
|
|
CN105163764B
(zh)
|
2013-03-15 |
2019-11-12 |
北卡罗来纳-查佩尔山大学 |
双重聚糖结合aav载体的方法和组合物
|
|
ES2704677T3
(es)
|
2013-04-18 |
2019-03-19 |
Fond Telethon |
Suministro eficaz de genes grandes por vectores de AAV duales
|
|
WO2014186746A1
(en)
|
2013-05-16 |
2014-11-20 |
University Of Florida Research Foundation, Inc. |
HAIRPIN mRNA ELEMENTS AND METHODS FOR THE REGULATION OF PROTEIN TRANSLATION
|
|
KR102307280B1
(ko)
|
2013-06-05 |
2021-10-01 |
듀크 유니버시티 |
Rna-가이드 유전자 편집 및 유전자 조절
|
|
KR20240172759A
(ko)
|
2013-06-17 |
2024-12-10 |
더 브로드 인스티튜트, 인코퍼레이티드 |
간의 표적화 및 치료를 위한 CRISPRCas 시스템, 벡터 및 조성물의 전달 및 용도
|
|
WO2015009575A1
(en)
|
2013-07-16 |
2015-01-22 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treatment of disorders related to cep290
|
|
EP3030665B9
(en)
|
2013-08-05 |
2023-10-04 |
Academisch Ziekenhuis Leiden H.O.D.N. Leids Universitair Medisch Centrum |
Recombinant aav-crumbs homologue composition and methods for treating lca-8 and progressive rp
|
|
LT3702466T
(lt)
|
2013-08-27 |
2023-02-27 |
Research Institute At Nationwide Children's Hospital |
Produktai ir būdai, skirti šoninės amiotrofinės sklerozės gydymui
|
|
NZ719477A
(en)
*
|
2013-11-11 |
2022-05-27 |
Sangamo Therapeutics Inc |
Methods and compositions for treating huntington’s disease
|
|
GB201401707D0
(en)
|
2014-01-31 |
2014-03-19 |
Sec Dep For Health The |
Adeno-associated viral vectors
|
|
GB201403684D0
(en)
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
|
WO2015150922A2
(en)
|
2014-03-17 |
2015-10-08 |
The Hospital For Sick Children |
β-HEXOSAMINIDASE PROTEIN VARIANTS AND ASSOCIATED METHODS FOR TREATING GM2 GANGLIOSIDOSES
|
|
AU2015231294B2
(en)
|
2014-03-18 |
2020-10-29 |
University Of Massachusetts |
rAAV-based compositions and methods for treating amyotrophic lateral sclerosis
|
|
WO2015164786A1
(en)
|
2014-04-25 |
2015-10-29 |
University Of Massachusetts |
Recombinant aav vectors useful for reducing immunity against transgene products
|
|
WO2015168666A2
(en)
|
2014-05-02 |
2015-11-05 |
Genzyme Corporation |
Aav vectors for retinal and cns gene therapy
|
|
JP6663859B2
(ja)
*
|
2014-05-20 |
2020-03-13 |
ユニバーシティー オブ アイオワ リサーチ ファウンデーション |
ハンチントン病の治療化合物
|
|
WO2016065001A1
(en)
|
2014-10-21 |
2016-04-28 |
University Of Massachusetts |
Recombinant aav variants and uses thereof
|
|
SMT201900347T1
(it)
*
|
2014-12-24 |
2019-07-11 |
Uniqure Ip Bv |
Soppressione del gene huntingtina indotta da rnai
|
|
CN107980062B
(zh)
*
|
2015-04-03 |
2022-11-25 |
马萨诸塞大学 |
用于靶向亨廷汀mRNA的寡核苷酸化合物
|
|
US20190000940A1
(en)
|
2015-07-31 |
2019-01-03 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of aadc deficiency
|
|
US10457940B2
(en)
|
2016-09-22 |
2019-10-29 |
University Of Massachusetts |
AAV treatment of Huntington's disease
|