|
US5549910A
(en)
|
1989-03-31 |
1996-08-27 |
The Regents Of The University Of California |
Preparation of liposome and lipid complex compositions
|
|
US5252334A
(en)
|
1989-09-08 |
1993-10-12 |
Cygnus Therapeutic Systems |
Solid matrix system for transdermal drug delivery
|
|
JP3218637B2
(ja)
|
1990-07-26 |
2001-10-15 |
大正製薬株式会社 |
安定なリポソーム水懸濁液
|
|
JP2958076B2
(ja)
|
1990-08-27 |
1999-10-06 |
株式会社ビタミン研究所 |
遺伝子導入用多重膜リポソーム及び遺伝子捕捉多重膜リポソーム製剤並びにその製法
|
|
US5399363A
(en)
|
1991-01-25 |
1995-03-21 |
Eastman Kodak Company |
Surface modified anticancer nanoparticles
|
|
US5478745A
(en)
|
1992-12-04 |
1995-12-26 |
University Of Pittsburgh |
Recombinant viral vector system
|
|
US5543158A
(en)
|
1993-07-23 |
1996-08-06 |
Massachusetts Institute Of Technology |
Biodegradable injectable nanoparticles
|
|
US5741516A
(en)
|
1994-06-20 |
1998-04-21 |
Inex Pharmaceuticals Corporation |
Sphingosomes for enhanced drug delivery
|
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
|
US5856152A
(en)
|
1994-10-28 |
1999-01-05 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV vector and methods of use therefor
|
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
US5697899A
(en)
|
1995-02-07 |
1997-12-16 |
Gensia |
Feedback controlled drug delivery system
|
|
IE80468B1
(en)
|
1995-04-04 |
1998-07-29 |
Elan Corp Plc |
Controlled release biodegradable nanoparticles containing insulin
|
|
US5738868A
(en)
|
1995-07-18 |
1998-04-14 |
Lipogenics Ltd. |
Liposome compositions and kits therefor
|
|
US6001650A
(en)
|
1995-08-03 |
1999-12-14 |
Avigen, Inc. |
High-efficiency wild-type-free AAV helper functions
|
|
US5656016A
(en)
|
1996-03-18 |
1997-08-12 |
Abbott Laboratories |
Sonophoretic drug delivery system
|
|
US5797898A
(en)
|
1996-07-02 |
1998-08-25 |
Massachusetts Institute Of Technology |
Microchip drug delivery devices
|
|
US5783208A
(en)
|
1996-07-19 |
1998-07-21 |
Theratech, Inc. |
Transdermal drug delivery matrix for coadministering estradiol and another steroid
|
|
US5779708A
(en)
|
1996-08-15 |
1998-07-14 |
Cyberdent, Inc. |
Intraosseous drug delivery device and method
|
|
CA2264482A1
(en)
|
1996-09-06 |
1998-03-12 |
The Trustees Of The University Of Pennsylvania |
An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase
|
|
US6177403B1
(en)
|
1996-10-21 |
2001-01-23 |
The Trustees Of The University Of Pennsylvania |
Compositions, methods, and apparatus for delivery of a macromolecular assembly to an extravascular tissue of an animal
|
|
US6544523B1
(en)
|
1996-11-13 |
2003-04-08 |
Chiron Corporation |
Mutant forms of Fas ligand and uses thereof
|
|
US6156303A
(en)
|
1997-06-11 |
2000-12-05 |
University Of Washington |
Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom
|
|
US6251677B1
(en)
|
1997-08-25 |
2001-06-26 |
The Trustees Of The University Of Pennsylvania |
Hybrid adenovirus-AAV virus and methods of use thereof
|
|
US6346415B1
(en)
|
1997-10-21 |
2002-02-12 |
Targeted Genetics Corporation |
Transcriptionally-activated AAV inverted terminal repeats (ITRS) for use with recombinant AAV vectors
|
|
US6953690B1
(en)
|
1998-03-20 |
2005-10-11 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
DE69939169D1
(de)
|
1998-05-28 |
2008-09-04 |
Us Gov Health & Human Serv |
Aav5 vektoren und deren verwendung
|
|
US20030110526A1
(en)
|
1998-08-25 |
2003-06-12 |
Robert H. Brown |
Dysferlin mutations
|
|
JP4693244B2
(ja)
|
1999-03-18 |
2011-06-01 |
ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア |
組換えアデノ随伴ウイルスのヘルパー無しの生産のための組成物および方法
|
|
US6498244B1
(en)
|
1999-05-28 |
2002-12-24 |
Cell Genesys, Inc. |
Adeno-associated virus capsid immunologic determinants
|
|
US6544786B1
(en)
|
1999-10-15 |
2003-04-08 |
University Of Pittsburgh Of The Commonwealth Of Higher Education |
Method and vector for producing and transferring trans-spliced peptides
|
|
US7638120B2
(en)
|
2000-03-14 |
2009-12-29 |
Thomas Jefferson University |
High transgene expression of a pseudotyped adeno-associated virus type
|
|
WO2002053703A2
(en)
|
2001-01-05 |
2002-07-11 |
Children's Hospital, Inc. |
Aav2 vectors and methods
|
|
US7749492B2
(en)
|
2001-01-05 |
2010-07-06 |
Nationwide Children's Hospital, Inc. |
AAV vectors and methods
|
|
EP1402043A1
(en)
|
2001-07-03 |
2004-03-31 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Methods of administering vectors to synaptically connected neurons
|
|
BR0211111A
(pt)
*
|
2001-07-12 |
2004-06-22 |
Univ Massachusetts |
Molécula de ácido nucleico isolada, vetor, célula hospedeira, transgene, precursor de rna engenheirado, animal transgênico não humano, e, método de induzir a interferência de ácido ribonucleico de um gene alvo em uma célula
|
|
CA2453405A1
(en)
|
2001-07-13 |
2003-01-23 |
University Of Iowa Research Foundation |
Pseudotyped adeno-associated viruses and uses thereof
|
|
EP1423537A4
(en)
*
|
2001-08-07 |
2006-11-29 |
Univ Delaware |
COMPOSITIONS AND METHODS FOR PREVENTING AND TREATING HUNTINGTON'S DISEASE
|
|
CN103589692B
(zh)
|
2001-11-13 |
2018-07-24 |
宾夕法尼亚大学托管会 |
检测和/或鉴定腺伴随病毒(aav)序列以及分离所鉴定的新型序列的方法
|
|
EP1463805B1
(en)
|
2001-12-17 |
2014-10-22 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) serotype 9 sequences, vectors containing same, and uses therefor
|
|
US20050137153A1
(en)
|
2002-02-20 |
2005-06-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of alpha-1 antitrypsin (AAT) gene expression using short interfering nucleic acid (siNA)
|
|
AU2003221733A1
(en)
|
2002-04-17 |
2003-11-03 |
University Of Florida Research Foundation, Inc. |
Improved raav vectors
|
|
WO2003089011A1
(en)
|
2002-04-19 |
2003-10-30 |
University Of Florida |
rAAV VECTOR-BASED COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MAMMALIAN DISEASES
|
|
US7235393B2
(en)
|
2002-04-29 |
2007-06-26 |
The Trustees Of The University Of Pennsylvania |
Method for direct rescue and amplification of integrated viruses from cellular DNA of tissues
|
|
US20060093589A1
(en)
|
2004-02-19 |
2006-05-04 |
Warrington Kenneth H |
Vp2-modified raav vector compositions and uses therefor
|
|
US20080274989A1
(en)
|
2002-08-05 |
2008-11-06 |
University Of Iowa Research Foundation |
Rna Interference Suppression of Neurodegenerative Diseases and Methods of Use Thereof
|
|
US20050106731A1
(en)
*
|
2002-08-05 |
2005-05-19 |
Davidson Beverly L. |
siRNA-mediated gene silencing with viral vectors
|
|
US20050255086A1
(en)
|
2002-08-05 |
2005-11-17 |
Davidson Beverly L |
Nucleic acid silencing of Huntington's Disease gene
|
|
US20060206949A1
(en)
|
2003-01-28 |
2006-09-14 |
Sylvain Arnould |
Custom-made meganuclease and use thereof
|
|
US7732591B2
(en)
*
|
2003-11-25 |
2010-06-08 |
Medtronic, Inc. |
Compositions, devices and methods for treatment of huntington's disease through intracranial delivery of sirna
|
|
US20040219528A1
(en)
|
2003-04-15 |
2004-11-04 |
Morris David W. |
Novel therapeutic targets in cancer
|
|
US7387896B2
(en)
|
2003-03-26 |
2008-06-17 |
The Regents Of The University Of Michigan |
MicroRNA vectors
|
|
US20060228800A1
(en)
|
2003-05-15 |
2006-10-12 |
Shi-Lung Lin |
Novel Transgenic Methods Using intronic RNA
|
|
CA2528012C
(en)
|
2003-06-02 |
2015-11-24 |
University Of Massachusetts |
Methods and compositions for controlling efficacy of rna silencing
|
|
US8680063B2
(en)
*
|
2003-09-12 |
2014-03-25 |
University Of Massachusetts |
RNA interference for the treatment of gain-of-function disorders
|
|
EP1668143B1
(en)
|
2003-09-30 |
2013-03-20 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) clades, sequences, vectors containing same, and uses therefor
|
|
ATE508190T1
(de)
|
2004-03-05 |
2011-05-15 |
Benitec Inc |
Mehrfachpromotor-expressionskassetten zurgleichzeitigen zuführung von rnai-agentien
|
|
WO2005096781A2
(en)
|
2004-04-06 |
2005-10-20 |
University Of Massachusetts |
Methods and compositions for treating gain-of-function disorders using rna interference
|
|
WO2005116224A2
(en)
|
2004-05-18 |
2005-12-08 |
Children's Memorial Hospital |
Tetracycline-regulated adeno-associated viral (aav) vectors for gene delivery to the nervous system
|
|
US7427396B2
(en)
|
2004-06-03 |
2008-09-23 |
Genzyme Corporation |
AAV vectors for gene delivery to the lung
|
|
US20060189564A1
(en)
|
2004-10-22 |
2006-08-24 |
Medtronic, Inc. |
Methods and sequences to suppress pro-inflamatory cytokine actions locally to treat pain
|
|
EP1828390B1
(en)
|
2004-12-15 |
2012-06-13 |
The University Of North Carolina At Chapel Hill |
Chimeric vectors
|
|
DE23193606T1
(de)
|
2005-04-07 |
2024-02-15 |
The Trustees Of The University Of Pennsylvania |
Verfahren zur erhöhung der funktion eines aav-vektors
|
|
US8283151B2
(en)
|
2005-04-29 |
2012-10-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Isolation, cloning and characterization of new adeno-associated virus (AAV) serotypes
|
|
DK2002003T3
(en)
|
2005-05-27 |
2016-03-21 |
Ospedale San Raffaele Srl |
Gene vector comprising miRNA
|
|
US20070213292A1
(en)
|
2005-08-10 |
2007-09-13 |
The Rockefeller University |
Chemically modified oligonucleotides for use in modulating micro RNA and uses thereof
|
|
ATE494372T1
(de)
|
2005-08-29 |
2011-01-15 |
Regulus Therapeutics Inc |
Verfahren für mir-122a-modulation
|
|
EP2484782B1
(en)
|
2006-01-05 |
2015-11-18 |
The Ohio State University Research Foundation |
MicroRNA-based methods and compositions for the diagnosis and treatment of solid cancers
|
|
EP2422819B1
(en)
|
2006-01-26 |
2017-03-01 |
Ionis Pharmaceuticals, Inc. |
Compositions and their uses directed to Huntingtin
|
|
WO2008016391A2
(en)
|
2006-01-31 |
2008-02-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
Self-complementary parvoviral vectors, and methods for making and using the same
|
|
EP2514824A3
(en)
|
2006-03-03 |
2013-01-23 |
Amorfix Life Sciences Ltd. |
Methods and compositions to treat and detect misfolded-SOD1 mediated diseases
|
|
US7588772B2
(en)
|
2006-03-30 |
2009-09-15 |
Board Of Trustees Of The Leland Stamford Junior University |
AAV capsid library and AAV capsid proteins
|
|
EP2046993A4
(en)
*
|
2006-07-07 |
2010-11-17 |
Univ Massachusetts |
RNA SILENCING COMPOSITIONS, AND METHODS OF TREATING HUNTINGTON CHOREA
|
|
US20080199961A1
(en)
*
|
2006-08-25 |
2008-08-21 |
Avi Biopharma, Inc. |
ANTISENSE COMPOSITION AND METHOD FOR INHIBITION OF miRNA BIOGENESIS
|
|
DK2094086T3
(da)
|
2006-11-08 |
2013-11-25 |
Veritas Bio LLC |
Indgivelse in vivo af dobbeltstrenget rna til en målcelle
|
|
DK2623605T3
(en)
|
2007-04-09 |
2019-03-25 |
Univ Florida |
RAAV VECTOR COMPOSITIONS WITH TYROSIN MODIFIED CAPSIDE PROTEINS AND PROCEDURES FOR USE THEREOF
|
|
US8257969B2
(en)
|
2007-04-12 |
2012-09-04 |
The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth |
Genetic suppression and replacement
|
|
US8399248B2
(en)
|
2007-05-03 |
2013-03-19 |
Merck Sharp & Dohme Corp. |
Methods of using MIR34 as a biomarker for TP53 functional status
|
|
US20080313773A1
(en)
*
|
2007-05-14 |
2008-12-18 |
The Rockefeller University |
Production of artificial micrornas using synthetic microrna precursors
|
|
WO2008147839A1
(en)
|
2007-05-23 |
2008-12-04 |
Dharmacon, Inc. |
Micro-rna scaffolds and non-naturally occurring micro-rnas
|
|
DK2164967T3
(en)
|
2007-05-31 |
2015-10-19 |
Univ Iowa Res Found |
Reduction of off-target rna interferenstoksicitet
|
|
EP2058401A1
(en)
|
2007-10-05 |
2009-05-13 |
Genethon |
Widespread gene delivery to motor neurons using peripheral injection of AAV vectors
|
|
US9090894B2
(en)
|
2007-12-17 |
2015-07-28 |
California Institute Of Technology |
Modulating immune system development and function through microRNA MIR-146
|
|
WO2009108274A2
(en)
|
2008-02-26 |
2009-09-03 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for adeno-associated virus (aav) with hi loop mutations
|
|
EP2268811A1
(en)
|
2008-03-07 |
2011-01-05 |
Santaris Pharma A/S |
Pharmaceutical compositions for treatment of microrna related diseases
|
|
WO2009146178A1
(en)
|
2008-04-15 |
2009-12-03 |
President And Fellows Of Harvard College |
Angiogenin and amyotrophic lateral sclerosis
|
|
US9217155B2
(en)
|
2008-05-28 |
2015-12-22 |
University Of Massachusetts |
Isolation of novel AAV'S and uses thereof
|
|
CA2726052A1
(en)
|
2008-06-04 |
2009-12-10 |
The Board Of Regents Of The University Of Texas System |
Modulation of gene expression through endogenous small rna targeting of gene promoters
|
|
US20110171262A1
(en)
|
2008-06-17 |
2011-07-14 |
Andrew Christian Bakker |
Parvoviral capsid with incorporated gly-ala repeat region
|
|
EP2310507A4
(en)
|
2008-07-08 |
2013-03-20 |
David Gladstone Inst |
METHOD AND COMPOSITIONS FOR ANGIOGENIC MODULATION
|
|
CN102203622A
(zh)
|
2008-09-04 |
2011-09-28 |
加利尼公司 |
突触小泡循环的测定和系统
|
|
WO2010034314A1
(en)
|
2008-09-24 |
2010-04-01 |
Aarhus Universitet |
Retroviral delivery of synthectic gene cassettes
|
|
WO2010071454A1
(en)
|
2008-12-17 |
2010-06-24 |
Auckland Uniservices Limited |
Adeno-associated viral vectors and uses thereof
|
|
WO2010099383A2
(en)
|
2009-02-26 |
2010-09-02 |
The Johns Hopkins University |
Compositions and methods for ex vivo hepatic nucleic acid delivery
|
|
MX2011011508A
(es)
*
|
2009-04-30 |
2012-02-13 |
San Raffaele Centro Fond |
Vector genico.
|
|
SI3988660T1
(sl)
|
2009-05-02 |
2025-09-30 |
Genzyme Corporation |
Genska terapija za nevrodegenerativne motnje
|
|
US8734809B2
(en)
*
|
2009-05-28 |
2014-05-27 |
University Of Massachusetts |
AAV's and uses thereof
|
|
EP2261242A1
(en)
|
2009-06-10 |
2010-12-15 |
Universite Catholique De Louvain |
Aspartate-N-acetyltransferase enzyme, diagnostic method and therapeutic method
|
|
EP3626823A1
(en)
*
|
2009-09-11 |
2020-03-25 |
Ionis Pharmaceuticals, Inc. |
Modulation of huntingtin expression
|
|
US20120270930A1
(en)
|
2009-10-29 |
2012-10-25 |
Academisch Ziekenhuis Leiden H.O.D.N. Lumc |
Methods and compositions for dysferlin exon-skipping
|
|
AU2010316982B2
(en)
|
2009-11-09 |
2013-09-12 |
Genepod Therapeutics Ab |
Novel viral vector construct for neuron specific continuous DOPA synthesis in vivo
|
|
WO2011062298A1
(ja)
|
2009-11-19 |
2011-05-26 |
国立大学法人岡山大学 |
遺伝子発現を上昇させるシステム及び該システムを保持したベクター
|
|
US9169494B2
(en)
|
2010-01-12 |
2015-10-27 |
The University Of North Carolina At Chapel Hill |
Restrictive inverted terminal repeats for viral vectors
|
|
EP2529020B1
(en)
|
2010-01-28 |
2018-04-25 |
The Children's Hospital of Philadelphia |
A scalable manufacturing platform for viral vector purification and viral vectors so purified for use in gene therapy
|
|
WO2011109380A1
(en)
|
2010-03-01 |
2011-09-09 |
The Children's Hospital Of Philadelphia |
Nucleic acids for targeting multiple regions of the hcv genome
|
|
CA2833912C
(en)
|
2010-04-23 |
2021-09-21 |
University Of Massachusetts |
Aav-based treatment of cholesterol-related disorders
|
|
DK2561073T3
(en)
|
2010-04-23 |
2016-12-12 |
Univ Massachusetts |
Aav vectors targeted to central nervous system and methods of use thereof
|
|
CA3050894C
(en)
|
2010-04-23 |
2022-10-18 |
University Of Massachusetts |
Multicistronic expression constructs
|
|
US8785413B2
(en)
|
2010-09-27 |
2014-07-22 |
Florida Atlantic University Research Corporation |
Materials and methods for the treatment of pathological neovascularization in the eye
|
|
ES2739804T3
(es)
|
2011-02-12 |
2020-02-04 |
Univ Iowa Res Found |
Compuestos terapéuticos
|
|
CN103502458B
(zh)
|
2011-02-17 |
2016-11-16 |
宾夕法尼亚大学托管会 |
用于改变组织特异性和改善aav9-介导的基因转移的组合物和方法
|
|
US20140201857A1
(en)
|
2013-01-14 |
2014-07-17 |
Recombinetics, Inc. |
Hornless livestock
|
|
EP2500434A1
(en)
|
2011-03-12 |
2012-09-19 |
Association Institut de Myologie |
Capsid-free AAV vectors, compositions, and methods for vector production and gene delivery
|
|
EP2699258A4
(en)
|
2011-04-15 |
2014-10-29 |
Us Sec Dep Of Health And Human Services |
AAV-mediated CTLA-4 gene transfer for the treatment of SJÖGREN SYNDROME
|
|
WO2012145624A2
(en)
|
2011-04-21 |
2012-10-26 |
University Of Massachusetts |
Raav-based compositions and methods for treating alpha-1 anti-trypsin deficiencies
|
|
US8609088B2
(en)
|
2011-05-10 |
2013-12-17 |
Regents Of The University Of Minnesota |
Intranasal delivery of therapeutic enzymes to the central nervous system for the treatment of lysosomal storage diseases
|
|
EP2766482B1
(en)
|
2011-10-11 |
2016-12-07 |
The Brigham and Women's Hospital, Inc. |
Micrornas in neurodegenerative disorders
|
|
US20130142861A1
(en)
|
2011-12-05 |
2013-06-06 |
National Yang Ming University |
Compositions And Method For Detecting And Treating Abnormal Liver Homeostasis And Hepatocarcinogenesis
|
|
BR112014020325A2
(pt)
|
2012-02-17 |
2017-08-08 |
Childrens Hospital Philadelphia |
composições de vetor do aav e métodos para a transferência de gene para as células, órgãos e tecidos
|
|
EP3470523A1
(en)
|
2012-05-09 |
2019-04-17 |
Oregon Health & Science University |
Adeno associated virus plasmids and vectors
|
|
CN104704123A
(zh)
|
2012-06-21 |
2015-06-10 |
肌肉学研究协会 |
基因治疗载体的广泛的基因递送
|
|
US20140066595A1
(en)
*
|
2012-09-04 |
2014-03-06 |
Thermo Fisher Scientific Biosciences Inc. |
Modulators of Protein Production in a Human Cell Line and Cell-free Extracts Produced Therefrom
|
|
SG10201707569YA
(en)
|
2012-12-12 |
2017-10-30 |
Broad Inst Inc |
Delivery, Engineering and Optimization of Systems, Methods and Compositions for Sequence Manipulation and Therapeutic Applications
|
|
EP2970946A4
(en)
|
2013-03-13 |
2016-09-07 |
Philadelphia Children Hospital |
ADENOASSOZED VIRUS VECTORS AND METHOD FOR USE THEREOF
|
|
ES2926774T3
(es)
|
2013-03-15 |
2022-10-28 |
Univ North Carolina Chapel Hill |
Métodos y composiciones para vectores AAV de doble unión de glicano
|
|
DK2986635T3
(en)
|
2013-04-18 |
2019-01-28 |
Fond Telethon |
EFFECTIVE DELIVERY OF BIG GENES THROUGH DUAL-AAV VECTORS
|
|
WO2014186746A1
(en)
|
2013-05-16 |
2014-11-20 |
University Of Florida Research Foundation, Inc. |
HAIRPIN mRNA ELEMENTS AND METHODS FOR THE REGULATION OF PROTEIN TRANSLATION
|
|
WO2014197748A2
(en)
|
2013-06-05 |
2014-12-11 |
Duke University |
Rna-guided gene editing and gene regulation
|
|
JP6738728B2
(ja)
|
2013-06-17 |
2020-08-19 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
肝臓ターゲティングおよび治療のためのＣＲＩＳＰＲ−Ｃａｓ系、ベクターおよび組成物の送達および使用
|
|
US10155794B2
(en)
|
2013-07-16 |
2018-12-18 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treatment of disorders related to CEP290
|
|
CN105980569A
(zh)
|
2013-08-05 |
2016-09-28 |
莱顿大学医学中心附属莱顿教学医院 |
重组aav-crumbs同源物组合物及治疗lca-8和进行性rp的方法
|
|
RS63942B1
(sr)
|
2013-08-27 |
2023-02-28 |
Res Inst Nationwide Childrens Hospital |
Proizvodi i postupci za lečenje amiotrofične lateralne skleroze
|
|
MX391904B
(es)
*
|
2013-11-11 |
2025-03-12 |
Sangamo Biosciences Inc |
Un represor genetico para usarse en el tratamiento de la enfermedad de huntington.
|
|
GB201401707D0
(en)
|
2014-01-31 |
2014-03-19 |
Sec Dep For Health The |
Adeno-associated viral vectors
|
|
GB201403684D0
(en)
|
2014-03-03 |
2014-04-16 |
King S College London |
Vector
|
|
EP3119892B1
(en)
|
2014-03-17 |
2021-03-10 |
The Hospital For Sick Children |
Beta-hexosaminidase protein variants and associated methods for treating gm2 gangliosdoses
|
|
JP6756700B2
(ja)
|
2014-03-18 |
2020-09-16 |
ユニバーシティ オブ マサチューセッツ |
筋萎縮性側索硬化症を処置するためのｒＡＡＶベースの組成物および方法
|
|
WO2015164786A1
(en)
|
2014-04-25 |
2015-10-29 |
University Of Massachusetts |
Recombinant aav vectors useful for reducing immunity against transgene products
|
|
LT3137497T
(lt)
*
|
2014-05-02 |
2021-07-26 |
Genzyme Corporation |
Aav vektoriai, skirti tinklainės ir cns genų terapijai
|
|
AU2015264263B2
(en)
|
2014-05-20 |
2021-08-05 |
University Of Iowa Research Foundation |
Huntington's disease therapeutic compounds
|
|
WO2016065001A1
(en)
|
2014-10-21 |
2016-04-28 |
University Of Massachusetts |
Recombinant aav variants and uses thereof
|
|
AU2015370903B2
(en)
|
2014-12-24 |
2021-06-17 |
Uniqure Ip B.V. |
RNAi induced huntingtin gene suppression
|
|
RS60762B1
(sr)
*
|
2015-04-03 |
2020-10-30 |
Univ Massachusetts |
Oligonukleotidna jedinjenja za ciljane irnk hantingtina
|
|
WO2017023724A1
(en)
|
2015-07-31 |
2017-02-09 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of aadc deficiency
|
|
US10457940B2
(en)
|
2016-09-22 |
2019-10-29 |
University Of Massachusetts |
AAV treatment of Huntington's disease
|