|
US10704021B2
(en)
|
2012-03-15 |
2020-07-07 |
Flodesign Sonics, Inc. |
Acoustic perfusion devices
|
|
CN105939767B
(zh)
|
2014-01-08 |
2018-04-06 |
弗洛设计声能学公司 |
具有双声电泳腔的声电泳装置
|
|
US11708572B2
(en)
|
2015-04-29 |
2023-07-25 |
Flodesign Sonics, Inc. |
Acoustic cell separation techniques and processes
|
|
US11377651B2
(en)
|
2016-10-19 |
2022-07-05 |
Flodesign Sonics, Inc. |
Cell therapy processes utilizing acoustophoresis
|
|
MX2020001593A
(es)
|
2017-08-09 |
2020-07-13 |
Bioverativ Therapeutics Inc |
Moleculas de acido nucleico y usos de las mismas.
|
|
JP2021505159A
(ja)
*
|
2017-12-06 |
2021-02-18 |
ジェネレーション バイオ カンパニー |
修飾型閉端ｄｎａ（ｃｅｄｎａ）を使用する遺伝子編集
|
|
CN114900773A
(zh)
|
2017-12-14 |
2022-08-12 |
弗洛设计声能学公司 |
声泳系统及其操作方法、控制声换能器及声学系统的方法
|
|
AU2019221642A1
(en)
*
|
2018-02-14 |
2020-07-09 |
Generation Bio Co. |
Non-viral DNA vectors and uses thereof for antibody and fusion protein production
|
|
JP7602454B2
(ja)
|
2018-08-09 |
2024-12-18 |
バイオベラティブ セラピューティクス インコーポレイテッド |
核酸分子及び非ウイルス遺伝子治療のためのそれらの使用
|
|
WO2020097417A1
(en)
*
|
2018-11-09 |
2020-05-14 |
Generation Bio Co. |
Modified closed-ended dna (cedna) comprising symmetrical modified inverted terminal repeats
|
|
GB201905651D0
(en)
*
|
2019-04-24 |
2019-06-05 |
Lightbio Ltd |
Nucleic acid constructs and methods for their manufacture
|
|
US20220228171A1
(en)
*
|
2019-07-17 |
2022-07-21 |
Generation Bio Co. |
Compositions and production of nicked closed-ended dna vectors
|
|
WO2021011842A1
(en)
*
|
2019-07-17 |
2021-01-21 |
Generation Bio Co. |
Synthetic production of single-stranded adeno associated viral dna vectors
|
|
WO2021030745A1
(en)
*
|
2019-08-15 |
2021-02-18 |
The Children's Hospital Of Philadelphia |
Combined transgene and intron-derived mirna therapy for treatment of sca1
|
|
CN114929205B
(zh)
*
|
2019-09-06 |
2024-09-03 |
世代生物公司 |
包括末端封闭式dna和可切割脂质的脂质纳米颗粒组合物及其使用方法
|
|
WO2021055760A1
(en)
|
2019-09-18 |
2021-03-25 |
Intergalactic Therapeutics, Inc. |
Synthetic dna vectors and methods of use
|
|
WO2021072031A1
(en)
*
|
2019-10-11 |
2021-04-15 |
Insideoutbio, Inc. |
Methods and compositions for the manufacture and use of circular dna encoded therapeutics for genetic disorders and other diseases
|
|
WO2021169167A1
(en)
*
|
2020-02-29 |
2021-09-02 |
Nanjing GenScript Biotech Co., Ltd. |
Method for treating coronavirus infections
|
|
DE102020111571A1
(de)
|
2020-03-11 |
2021-09-16 |
Immatics US, Inc. |
Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
|
|
IL296660A
(en)
*
|
2020-03-24 |
2022-11-01 |
Generation Bio Co |
Non-viral DNA vectors and their use for therapeutic expression of factor ix
|
|
IL296662A
(en)
*
|
2020-03-24 |
2022-11-01 |
Generation Bio Co |
Non-viral dna vectors and uses thereof for expressing gaucher therapeutics
|
|
CN115968280A
(zh)
*
|
2020-05-18 |
2023-04-14 |
世代生物公司 |
新型脂质及其纳米颗粒组合物
|
|
MX2023001109A
(es)
|
2020-07-27 |
2023-04-24 |
Anjarium Biosciences Ag |
Composiciones de moleculas de adn, metodos para elaborar las mismas, y metodos de usos de las mismas.
|
|
AU2021330936A1
(en)
|
2020-08-23 |
2023-05-04 |
Bioverativ Therapeutics Inc. |
MODIFIED BACULOVIRUS SYSTEM FOR IMPROVED PRODUCTION OF CLOSED-ENDED DNA (ceDNA)
|
|
US20220243201A1
(en)
*
|
2020-08-23 |
2022-08-04 |
Bioverativ Therapeutics Inc. |
Engineered itr sequences and methods of use
|
|
CA3191743A1
(en)
*
|
2020-09-16 |
2022-03-24 |
Generation Bio Co. |
Non-viral dna vectors and uses thereof for expressing fviii therapeutics
|
|
MX2023003019A
(es)
*
|
2020-09-16 |
2023-05-08 |
Generation Bio Co |
Vectores de adn de extremo cerrado y usos de estos para expresar fenilalanina hidroxilasa (pah).
|
|
GB202014751D0
(en)
*
|
2020-09-18 |
2020-11-04 |
Lightbio Ltd |
Targeting vector
|
|
WO2022198025A2
(en)
*
|
2021-03-19 |
2022-09-22 |
Generation Bio Co. |
Non-viral dna vectors and uses thereof for expressing pfic therapeutics
|
|
WO2022232029A2
(en)
*
|
2021-04-26 |
2022-11-03 |
University Of Florida Research Foundation, Incorporated |
Synthetic aav vectors for repeated delivery of therapeutic genes
|
|
JP2024515788A
(ja)
*
|
2021-04-27 |
2024-04-10 |
ジェネレーション バイオ カンパニー |
治療抗体を発現する非ウイルスｄｎａベクター及びその使用
|
|
US20240216535A1
(en)
*
|
2021-04-27 |
2024-07-04 |
Generation Bio Co. |
Non-viral dna vectors expressing anti-coronavirus antibodies and uses thereof
|
|
EP4333886A4
(en)
*
|
2021-05-07 |
2025-11-12 |
Generation Bio Co |
NON-VIRAL DNA VECTORS FOR VACCINE ADMINISTRATION
|
|
WO2022236016A1
(en)
*
|
2021-05-07 |
2022-11-10 |
Generation Bio Co. |
Lyophilized non-viral dna vector compositions and uses thereof
|
|
WO2023069948A1
(en)
*
|
2021-10-18 |
2023-04-27 |
Flagship Pioneering Innovations Vii, Llc |
Dna compositions and related methods
|
|
EP4493212A1
(en)
|
2022-03-14 |
2025-01-22 |
Generation Bio Co. |
Heterologous prime boost vaccine compositions and methods of use
|
|
CN117802161A
(zh)
*
|
2022-06-30 |
2024-04-02 |
苏州吉恒基因科技有限公司 |
精准重组腺相关病毒载体及其用途
|
|
WO2024040222A1
(en)
*
|
2022-08-19 |
2024-02-22 |
Generation Bio Co. |
Cleavable closed-ended dna (cedna) and methods of use thereof
|
|
JP2026508358A
(ja)
|
2023-03-02 |
2026-03-10 |
クリスタル バイオテック インコーポレイテッド |
がん治療用のインターロイキン－２およびインターロイキン－１２
|
|
US11891617B1
(en)
*
|
2023-03-27 |
2024-02-06 |
Genecraft Inc. |
Modified complex platform of adeno-associated virus with improved rate of expression of loaded genes and reduced genotoxicity
|
|
US11993783B1
(en)
*
|
2023-03-27 |
2024-05-28 |
Genecraft Inc. |
Nucleic acid molecule comprising asymmetrically modified ITR for improving expression rate of inserted gene, and use thereof
|
|
US11767541B1
(en)
*
|
2023-03-27 |
2023-09-26 |
Genecraft, Inc. |
Adeno-associated virus complex with improved expression of RUNX3 gene and uses for preventing or treating KRAS mutated lung cancer
|
|
WO2024220969A2
(en)
*
|
2023-04-21 |
2024-10-24 |
Arizona Board Of Regents On Behalf Of Arizona State University |
Novel transmembrane sensors and method of characterization for lysis-free detection of intracellular targets
|
|
CN122341729A
(zh)
*
|
2023-11-30 |
2026-07-03 |
赛诺菲 |
末端封闭的dna分子的纯化
|
|
WO2026085495A1
(en)
|
2024-10-18 |
2026-04-23 |
Generation Bio Co. |
Synthetic partially single-stranded nucleic acid compositions and uses and methods therefor
|