JP2019531759A5 - - Google Patents
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- JP2019531759A5 JP2019531759A5 JP2019523138A JP2019523138A JP2019531759A5 JP 2019531759 A5 JP2019531759 A5 JP 2019531759A5 JP 2019523138 A JP2019523138 A JP 2019523138A JP 2019523138 A JP2019523138 A JP 2019523138A JP 2019531759 A5 JP2019531759 A5 JP 2019531759A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- protein
- seq
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000623 proteins and genes Proteins 0.000 claims 54
- 150000001413 amino acids Chemical group 0.000 claims 50
- 235000018102 proteins Nutrition 0.000 claims 42
- 102000004169 proteins and genes Human genes 0.000 claims 42
- 238000000034 method Methods 0.000 claims 31
- 244000005700 microbiome Species 0.000 claims 17
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims 16
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 16
- 229910052717 sulfur Inorganic materials 0.000 claims 16
- 239000011593 sulfur Substances 0.000 claims 16
- 239000013076 target substance Substances 0.000 claims 14
- 108090000790 Enzymes Proteins 0.000 claims 11
- 102000004190 Enzymes Human genes 0.000 claims 11
- 238000007792 addition Methods 0.000 claims 10
- 125000000539 amino acid group Chemical group 0.000 claims 10
- 238000012217 deletion Methods 0.000 claims 10
- 230000037430 deletion Effects 0.000 claims 10
- 230000014509 gene expression Effects 0.000 claims 10
- 238000003780 insertion Methods 0.000 claims 10
- 230000037431 insertion Effects 0.000 claims 10
- 238000006467 substitution reaction Methods 0.000 claims 10
- 235000013878 L-cysteine Nutrition 0.000 claims 8
- 239000004201 L-cysteine Substances 0.000 claims 8
- 230000001851 biosynthetic effect Effects 0.000 claims 7
- 230000000694 effects Effects 0.000 claims 7
- YQUVCSBJEUQKSH-UHFFFAOYSA-N 3,4-dihydroxybenzoic acid Chemical group OC(=O)C1=CC=C(O)C(O)=C1 YQUVCSBJEUQKSH-UHFFFAOYSA-N 0.000 claims 6
- 238000004519 manufacturing process Methods 0.000 claims 5
- 241000894006 Bacteria Species 0.000 claims 4
- 238000006243 chemical reaction Methods 0.000 claims 4
- 230000001276 controlling effect Effects 0.000 claims 4
- 239000002243 precursor Substances 0.000 claims 4
- WKOLLVMJNQIZCI-UHFFFAOYSA-N vanillic acid Chemical compound COC1=CC(C(O)=O)=CC=C1O WKOLLVMJNQIZCI-UHFFFAOYSA-N 0.000 claims 4
- TUUBOHWZSQXCSW-UHFFFAOYSA-N vanillic acid Natural products COC1=CC(O)=CC(C(O)=O)=C1 TUUBOHWZSQXCSW-UHFFFAOYSA-N 0.000 claims 4
- 230000015572 biosynthetic process Effects 0.000 claims 3
- 101150075677 cysR gene Proteins 0.000 claims 3
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 claims 3
- FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 claims 3
- 235000012141 vanillin Nutrition 0.000 claims 3
- YOMSJEATGXXYPX-UHFFFAOYSA-N 2-methoxy-4-vinylphenol Chemical compound COC1=CC(C=C)=CC=C1O YOMSJEATGXXYPX-UHFFFAOYSA-N 0.000 claims 2
- IBGBGRVKPALMCQ-UHFFFAOYSA-N 3,4-dihydroxybenzaldehyde Chemical compound OC1=CC=C(C=O)C=C1O IBGBGRVKPALMCQ-UHFFFAOYSA-N 0.000 claims 2
- CHWNEIVBYREQRF-UHFFFAOYSA-N 4-Ethyl-2-methoxyphenol Chemical compound CCC1=CC=C(O)C(OC)=C1 CHWNEIVBYREQRF-UHFFFAOYSA-N 0.000 claims 2
- 241000186216 Corynebacterium Species 0.000 claims 2
- 241000186226 Corynebacterium glutamicum Species 0.000 claims 2
- 101150103751 FPR2 gene Proteins 0.000 claims 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims 2
- AHLPHDHHMVZTML-BYPYZUCNSA-N L-Ornithine Chemical compound NCCC[C@H](N)C(O)=O AHLPHDHHMVZTML-BYPYZUCNSA-N 0.000 claims 2
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 claims 2
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 2
- 108050008280 Shikimate dehydrogenase Proteins 0.000 claims 2
- 230000001580 bacterial effect Effects 0.000 claims 2
- 239000006227 byproduct Substances 0.000 claims 2
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 101150052442 cysD gene Proteins 0.000 claims 2
- 101150041643 cysH gene Proteins 0.000 claims 2
- 101150100268 cysI gene Proteins 0.000 claims 2
- 101150086660 cysN gene Proteins 0.000 claims 2
- 101150118721 cysX gene Proteins 0.000 claims 2
- 101150111924 cysZ gene Proteins 0.000 claims 2
- LHGVFZTZFXWLCP-UHFFFAOYSA-N guaiacol Chemical compound COC1=CC=CC=C1O LHGVFZTZFXWLCP-UHFFFAOYSA-N 0.000 claims 2
- 239000000047 product Substances 0.000 claims 2
- 101150048722 ssuR gene Proteins 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- KSEBMYQBYZTDHS-HWKANZROSA-M (E)-Ferulic acid Natural products COC1=CC(\C=C\C([O-])=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-M 0.000 claims 1
- QDGAVODICPCDMU-UHFFFAOYSA-N 2-amino-3-[3-[bis(2-chloroethyl)amino]phenyl]propanoic acid Chemical compound OC(=O)C(N)CC1=CC=CC(N(CCCl)CCCl)=C1 QDGAVODICPCDMU-UHFFFAOYSA-N 0.000 claims 1
- 108010038550 3-dehydroquinate dehydratase Proteins 0.000 claims 1
- 108050006180 3-dehydroquinate synthase Proteins 0.000 claims 1
- SLWWJZMPHJJOPH-PHDIDXHHSA-N 3-dehydroshikimic acid Chemical compound O[C@@H]1CC(C(O)=O)=CC(=O)[C@H]1O SLWWJZMPHJJOPH-PHDIDXHHSA-N 0.000 claims 1
- 108010021809 Alcohol dehydrogenase Proteins 0.000 claims 1
- 102000007698 Alcohol dehydrogenase Human genes 0.000 claims 1
- 102000008170 Aldehyde Oxidoreductases Human genes 0.000 claims 1
- 108010060441 Aldehyde Oxidoreductases Proteins 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- FFEARJCKVFRZRR-SCSAIBSYSA-N D-methionine Chemical compound CSCC[C@@H](N)C(O)=O FFEARJCKVFRZRR-SCSAIBSYSA-N 0.000 claims 1
- SLWWJZMPHJJOPH-UHFFFAOYSA-N DHS Natural products OC1CC(C(O)=O)=CC(=O)C1O SLWWJZMPHJJOPH-UHFFFAOYSA-N 0.000 claims 1
- 241000588921 Enterobacteriaceae Species 0.000 claims 1
- 241000588722 Escherichia Species 0.000 claims 1
- 241000588724 Escherichia coli Species 0.000 claims 1
- 239000004471 Glycine Substances 0.000 claims 1
- 101000615488 Homo sapiens Methyl-CpG-binding domain protein 2 Proteins 0.000 claims 1
- 108090001042 Hydro-Lyases Proteins 0.000 claims 1
- 102000004867 Hydro-Lyases Human genes 0.000 claims 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 claims 1
- 229930064664 L-arginine Natural products 0.000 claims 1
- 235000014852 L-arginine Nutrition 0.000 claims 1
- SSISHJJTAXXQAX-ZETCQYMHSA-N L-ergothioneine Chemical compound C[N+](C)(C)[C@H](C([O-])=O)CC1=CNC(=S)N1 SSISHJJTAXXQAX-ZETCQYMHSA-N 0.000 claims 1
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 claims 1
- 102100021299 Methyl-CpG-binding domain protein 2 Human genes 0.000 claims 1
- AHLPHDHHMVZTML-UHFFFAOYSA-N Orn-delta-NH2 Natural products NCCCC(N)C(O)=O AHLPHDHHMVZTML-UHFFFAOYSA-N 0.000 claims 1
- 229910019142 PO4 Inorganic materials 0.000 claims 1
- 102000055027 Protein Methyltransferases Human genes 0.000 claims 1
- 108700040121 Protein Methyltransferases Proteins 0.000 claims 1
- 108010016080 Protocatechuate-3,4-Dioxygenase Proteins 0.000 claims 1
- MEFKEPWMEQBLKI-AIRLBKTGSA-N S-adenosyl-L-methioninate Chemical compound O[C@@H]1[C@H](O)[C@@H](C[S+](CC[C@H](N)C([O-])=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 MEFKEPWMEQBLKI-AIRLBKTGSA-N 0.000 claims 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 1
- 102000004357 Transferases Human genes 0.000 claims 1
- 108090000992 Transferases Proteins 0.000 claims 1
- 229960001570 ademetionine Drugs 0.000 claims 1
- 150000003934 aromatic aldehydes Chemical class 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 241000186254 coryneform bacterium Species 0.000 claims 1
- 229960003624 creatine Drugs 0.000 claims 1
- 239000006046 creatine Substances 0.000 claims 1
- 229940093497 ergothioneine Drugs 0.000 claims 1
- KSEBMYQBYZTDHS-HWKANZROSA-N ferulic acid Chemical compound COC1=CC(\C=C\C(O)=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-N 0.000 claims 1
- 229940114124 ferulic acid Drugs 0.000 claims 1
- KSEBMYQBYZTDHS-UHFFFAOYSA-N ferulic acid Natural products COC1=CC(C=CC(O)=O)=CC=C1O KSEBMYQBYZTDHS-UHFFFAOYSA-N 0.000 claims 1
- 235000001785 ferulic acid Nutrition 0.000 claims 1
- 229960001867 guaiacol Drugs 0.000 claims 1
- 229960002885 histidine Drugs 0.000 claims 1
- GJRGEVKCJPPZIT-UHFFFAOYSA-N isomugineic acid Natural products OC(=O)C(O)CCNC(C(O)=O)C(O)CN1CCC1C(O)=O GJRGEVKCJPPZIT-UHFFFAOYSA-N 0.000 claims 1
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 claims 1
- 229960003987 melatonin Drugs 0.000 claims 1
- 239000002207 metabolite Substances 0.000 claims 1
- GJRGEVKCJPPZIT-JBDRJPRFSA-N mugineic acid Chemical compound OC(=O)[C@@H](O)CCN[C@H](C(O)=O)[C@@H](O)CN1CC[C@H]1C(O)=O GJRGEVKCJPPZIT-JBDRJPRFSA-N 0.000 claims 1
- 229960003104 ornithine Drugs 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 229920000768 polyamine Polymers 0.000 claims 1
- 229960003371 protocatechualdehyde Drugs 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- IFGCUJZIWBUILZ-UHFFFAOYSA-N sodium 2-[[2-[[hydroxy-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyphosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid Chemical compound [Na+].C=1NC2=CC=CC=C2C=1CC(C(O)=O)NC(=O)C(CC(C)C)NP(O)(=O)OC1OC(C)C(O)C(O)C1O IFGCUJZIWBUILZ-UHFFFAOYSA-N 0.000 claims 1
- QURCVMIEKCOAJU-UHFFFAOYSA-N trans-isoferulic acid Natural products COC1=CC=C(C=CC(O)=O)C=C1O QURCVMIEKCOAJU-UHFFFAOYSA-N 0.000 claims 1
- 229960004441 tyrosine Drugs 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022075719A JP7331985B2 (ja) | 2016-10-26 | 2022-05-02 | 目的物質の製造方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662413030P | 2016-10-26 | 2016-10-26 | |
| US62/413,030 | 2016-10-26 | ||
| US201662417602P | 2016-11-04 | 2016-11-04 | |
| US62/417,602 | 2016-11-04 | ||
| PCT/JP2017/038799 WO2018079687A1 (en) | 2016-10-26 | 2017-10-26 | Method for producing objective substance |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022075719A Division JP7331985B2 (ja) | 2016-10-26 | 2022-05-02 | 目的物質の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019531759A JP2019531759A (ja) | 2019-11-07 |
| JP2019531759A5 true JP2019531759A5 (enExample) | 2020-11-26 |
Family
ID=61226628
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019523138A Pending JP2019531759A (ja) | 2016-10-26 | 2017-10-26 | 目的物質の製造方法 |
| JP2022075719A Active JP7331985B2 (ja) | 2016-10-26 | 2022-05-02 | 目的物質の製造方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022075719A Active JP7331985B2 (ja) | 2016-10-26 | 2022-05-02 | 目的物質の製造方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20190249205A1 (enExample) |
| EP (1) | EP3532627A1 (enExample) |
| JP (2) | JP2019531759A (enExample) |
| CN (1) | CN109952380B (enExample) |
| WO (1) | WO2018079687A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112021019284A2 (pt) | 2019-03-29 | 2022-02-01 | Ajinomoto Kk | Métodos para produzir alolactose e para produzir um indutor de expressão gênica |
| CN111748506B (zh) * | 2019-03-29 | 2022-07-05 | 中国科学院微生物研究所 | 产胍基乙酸的工程菌及其构建方法与应用 |
| WO2020226087A1 (ja) | 2019-05-08 | 2020-11-12 | 味の素株式会社 | バニリンの製造方法 |
| EP3839051A1 (en) * | 2019-12-19 | 2021-06-23 | Evonik Operations GmbH | Method for the fermentative production of guanidinoacetic acid |
| JPWO2021177392A1 (enExample) | 2020-03-04 | 2021-09-10 | ||
| MY207800A (en) * | 2020-07-09 | 2025-03-20 | Evonik Operations Gmbh | Method for the fermentative production of guanidinoacetic acid |
| KR20230035565A (ko) * | 2020-07-09 | 2023-03-14 | 에보닉 오퍼레이션스 게엠베하 | 구아니디노아세트산의 발효적 생산 방법 |
| CN114276947B (zh) * | 2021-10-12 | 2024-07-23 | 湖北远大生物技术有限公司 | 酶促转化制备l-半胱氨酸的方法和用途 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5089592A (enExample) | 1973-12-13 | 1975-07-18 | ||
| JPS57134500A (en) | 1981-02-12 | 1982-08-19 | Kyowa Hakko Kogyo Co Ltd | Plasmid pcg1 |
| JPS57183799A (en) | 1981-04-17 | 1982-11-12 | Kyowa Hakko Kogyo Co Ltd | Novel plasmid |
| JPS5835197A (ja) | 1981-08-26 | 1983-03-01 | Kyowa Hakko Kogyo Co Ltd | プラスミドｐｃｇ２ |
| JPS58192900A (ja) | 1982-05-04 | 1983-11-10 | Ajinomoto Co Inc | 複合プラスミド |
| JPH01191686A (ja) | 1988-01-26 | 1989-08-01 | Mitsubishi Petrochem Co Ltd | 複合プラスミド |
| FR2627508B1 (fr) | 1988-02-22 | 1990-10-05 | Eurolysine | Procede pour l'integration d'un gene choisi sur le chromosome d'une bacterie et bacterie obtenue par ledit procede |
| JP2678995B2 (ja) | 1988-09-08 | 1997-11-19 | 三菱化学株式会社 | トリプトフアンシンターゼの製造法 |
| US5185262A (en) | 1988-07-27 | 1993-02-09 | Mitsubishi Petrochemical Co., Ltd. | DNA fragment containing gene which encodes the function of stabilizing plasmid in host microorganism |
| JPH02207791A (ja) | 1989-02-07 | 1990-08-17 | Ajinomoto Co Inc | 微生物の形質転換法 |
| JP2973446B2 (ja) | 1990-01-11 | 1999-11-08 | 三菱化学株式会社 | 新規プラスミドベクター |
| JPH07108228B2 (ja) | 1990-10-15 | 1995-11-22 | 味の素株式会社 | 温度感受性プラスミド |
| US5128253A (en) * | 1991-05-31 | 1992-07-07 | Kraft General Foods, Inc. | Bioconversion process for the production of vanillin |
| JPH05244941A (ja) | 1992-03-03 | 1993-09-24 | Toyo Ink Mfg Co Ltd | Ｎａｄｈ依存性パラヒドロキシ安息香酸ヒドロキシラーゼ及びその製造方法 |
| US5272073A (en) | 1992-06-30 | 1993-12-21 | Purdue Research Foundation | Biocatalytic synthesis of catechol from glucose |
| JPH0775589A (ja) | 1993-09-08 | 1995-03-20 | Kawasaki Steel Corp | プロトカテキュ酸の製造方法 |
| WO1996023073A1 (en) | 1995-01-23 | 1996-08-01 | Novo Nordisk A/S | Dna integration by transposition |
| JPH0970291A (ja) | 1995-06-30 | 1997-03-18 | Ajinomoto Co Inc | 人工トランスポゾンを用いた遺伝子増幅方法 |
| JP4168463B2 (ja) | 1996-12-05 | 2008-10-22 | 味の素株式会社 | Ｌ−リジンの製造法 |
| AU756507B2 (en) | 1998-03-18 | 2003-01-16 | Ajinomoto Co., Inc. | L-glutamic acid-producing bacterium and method for producing L-glutamic acid |
| US6372461B1 (en) | 1998-09-18 | 2002-04-16 | Board Of Directors Operating Michigan State University | Synthesis of vanillin from a carbon source |
| JP2000262288A (ja) | 1999-03-16 | 2000-09-26 | Ajinomoto Co Inc | コリネ型細菌の温度感受性プラスミド |
| CN101255431B (zh) | 2000-03-09 | 2012-05-16 | 赢创德固赛有限责任公司 | 编码代谢途径蛋白的谷氨酸棒杆菌基因 |
| US7846697B2 (en) | 2003-06-19 | 2010-12-07 | BLMaps | Method of producing a low molecular weight organic compound in a cell |
| PL1651758T3 (pl) | 2003-07-29 | 2009-04-30 | Ajinomoto Kk | Sposób wytwarzania L-lizyny lub L-treoniny przy użyciu bakterii Escherichia o atenuowanej aktywności enzymu jabłczanowego |
| JP4882063B2 (ja) | 2005-10-12 | 2012-02-22 | 国立大学法人東京農工大学 | テレフタル酸の代謝に関与する新規遺伝子 |
| EP1947190B1 (en) | 2005-10-18 | 2017-11-29 | Ajinomoto Co., Inc. | Process for production of succinic acid |
| RU2418069C2 (ru) | 2006-09-29 | 2011-05-10 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | Способ конструирования рекомбинантных бактерий, принадлежащих к роду pantoea, и способ продукции l-аминокислот с использованием бактерий, принадлежащих к роду pantoea |
| JP2010130899A (ja) * | 2007-03-14 | 2010-06-17 | Ajinomoto Co Inc | Ｌ−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法 |
| JP2010207094A (ja) | 2009-03-06 | 2010-09-24 | Genaris Inc | プロトカテク酸の製造法 |
| CN103987840A (zh) | 2011-08-08 | 2014-08-13 | 国际香料香精公司 | 用于香草醛或香草醛β-D-葡萄糖苷的生物合成的组合物和方法 |
| BR112013016373B1 (pt) | 2011-11-11 | 2021-05-18 | Ajinomoto Co., Inc | método para produzir uma substância alvo |
| CA2888636C (en) | 2012-11-05 | 2022-11-29 | Evolva Sa | Vanillin synthase |
| WO2015009558A1 (en) * | 2013-07-16 | 2015-01-22 | International Flavors & Fragrances Inc. | Compositions and methods for the biosynthesis of vanillin or vanillin beta-d-glucoside |
| JP2017525379A (ja) * | 2014-09-01 | 2017-09-07 | メタボリック エクスプローラー | メチオニン排出を改善した発酵によるメチオニン産生の方法及び微生物 |
| CN108026516A (zh) * | 2015-08-07 | 2018-05-11 | 赢创德固赛有限公司 | 通过发酵的蛋白硫代羧化物依赖性l-甲硫氨酸生产 |
| JP6881448B2 (ja) * | 2015-10-27 | 2021-06-02 | 味の素株式会社 | アルデヒドの製造方法 |
-
2017
- 2017-10-26 JP JP2019523138A patent/JP2019531759A/ja active Pending
- 2017-10-26 EP EP17842339.8A patent/EP3532627A1/en active Pending
- 2017-10-26 WO PCT/JP2017/038799 patent/WO2018079687A1/en not_active Ceased
- 2017-10-26 CN CN201780066784.XA patent/CN109952380B/zh active Active
-
2019
- 2019-04-24 US US16/392,756 patent/US20190249205A1/en not_active Abandoned
-
2022
- 2022-05-02 JP JP2022075719A patent/JP7331985B2/ja active Active
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