JP2019527053A5 - - Google Patents

Download PDF

Info

Publication number
JP2019527053A5
JP2019527053A5 JP2019500261A JP2019500261A JP2019527053A5 JP 2019527053 A5 JP2019527053 A5 JP 2019527053A5 JP 2019500261 A JP2019500261 A JP 2019500261A JP 2019500261 A JP2019500261 A JP 2019500261A JP 2019527053 A5 JP2019527053 A5 JP 2019527053A5
Authority
JP
Japan
Prior art keywords
polypeptide
item
sfgfr3
growth factor
fibroblast growth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2019500261A
Other languages
English (en)
Japanese (ja)
Other versions
JP7046903B2 (ja
JP2019527053A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2017/067119 external-priority patent/WO2018007597A1/en
Publication of JP2019527053A publication Critical patent/JP2019527053A/ja
Publication of JP2019527053A5 publication Critical patent/JP2019527053A5/ja
Priority to JP2022046573A priority Critical patent/JP7348980B2/ja
Application granted granted Critical
Publication of JP7046903B2 publication Critical patent/JP7046903B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2019500261A 2016-07-07 2017-07-07 可溶性線維芽細胞成長因子受容体3(sFGFR3)ポリペプチドおよびその使用 Expired - Fee Related JP7046903B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022046573A JP7348980B2 (ja) 2016-07-07 2022-03-23 可溶性線維芽細胞成長因子受容体3(sFGFR3)ポリペプチドおよびその使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662359607P 2016-07-07 2016-07-07
US62/359,607 2016-07-07
US201762467478P 2017-03-06 2017-03-06
US62/467,478 2017-03-06
PCT/EP2017/067119 WO2018007597A1 (en) 2016-07-07 2017-07-07 Soluble fibroblast growth factor receptor 3 (sfgfr3) polypeptides and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022046573A Division JP7348980B2 (ja) 2016-07-07 2022-03-23 可溶性線維芽細胞成長因子受容体3(sFGFR3)ポリペプチドおよびその使用

Publications (3)

Publication Number Publication Date
JP2019527053A JP2019527053A (ja) 2019-09-26
JP2019527053A5 true JP2019527053A5 (enExample) 2020-08-20
JP7046903B2 JP7046903B2 (ja) 2022-04-04

Family

ID=59381265

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019500261A Expired - Fee Related JP7046903B2 (ja) 2016-07-07 2017-07-07 可溶性線維芽細胞成長因子受容体3(sFGFR3)ポリペプチドおよびその使用
JP2022046573A Active JP7348980B2 (ja) 2016-07-07 2022-03-23 可溶性線維芽細胞成長因子受容体3(sFGFR3)ポリペプチドおよびその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022046573A Active JP7348980B2 (ja) 2016-07-07 2022-03-23 可溶性線維芽細胞成長因子受容体3(sFGFR3)ポリペプチドおよびその使用

Country Status (20)

Country Link
US (3) US10294289B2 (enExample)
EP (2) EP3481859B1 (enExample)
JP (2) JP7046903B2 (enExample)
KR (2) KR102432192B1 (enExample)
CN (1) CN109715658B (enExample)
AU (2) AU2017294551B2 (enExample)
BR (1) BR112019000257A2 (enExample)
CA (1) CA3029877C (enExample)
DK (1) DK3481859T3 (enExample)
ES (1) ES2912559T3 (enExample)
HU (1) HUE058734T2 (enExample)
IL (1) IL264030A (enExample)
MX (1) MX2018016257A (enExample)
PL (1) PL3481859T3 (enExample)
PT (1) PT3481859T (enExample)
RU (1) RU2751483C2 (enExample)
SG (1) SG11201900074WA (enExample)
SI (1) SI3481859T1 (enExample)
WO (1) WO2018007597A1 (enExample)
ZA (1) ZA201900507B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20150344855A1 (en) 2013-01-16 2015-12-03 INSERM (Institut National de la Santé et de la Recherche Médicale A Soluble Fibroblast Growth Factor Receptor 3 (FGR3) Polypeptide For Use In The Prevention Or Treatment Of Skeletal Growth Retardation Disorders
KR102432192B1 (ko) 2016-07-07 2022-08-12 화이자 인코포레이티드 가용성 섬유아세포 성장 인자 수용체 3(sfgfr3) 폴리펩티드 및 이의 용도
EP3684394A1 (en) * 2017-09-20 2020-07-29 Pfizer Inc. Treatment of abnormal visceral fat deposition using soluble fibroblast growth factor receptor 3 (sfgfr3) polypeptides
WO2020243478A1 (en) * 2019-05-29 2020-12-03 Massachusetts Eye And Ear Infirmary Fibroblast growth factor 2 (fgf2) for treatment of human sensorineural hearing loss
US11625937B2 (en) * 2020-04-06 2023-04-11 Toyota Motor Engineering & Manufacturing North America, Inc. Methods and systems for monitoring human body weight with vehicle sensors and big data AI analytics
WO2022106976A1 (en) 2020-11-18 2022-05-27 Pfizer Inc. Stable pharmaceutical formulations of soluble fgfr3 decoys
JP2022184798A (ja) 2021-06-01 2022-12-13 ファイザー・インク sFGFR3ポリペプチドを生産するための細胞培養方法
WO2024104922A1 (en) 2022-11-14 2024-05-23 Ascendis Pharma Growth Disorders A/S Method of improving skeletal muscle function
KR20250162619A (ko) 2023-03-20 2025-11-18 아센디스 파마 그로우쓰 디스오더스 에이/에스 연골무형성증을 가진 인간 대상에서의 흉요추 변형의 치료 방법
CN116284327A (zh) * 2023-03-28 2023-06-23 中国药科大学 一种靶向肿瘤的成纤维细胞生长因子19的重组蛋白及其应用
WO2024218715A1 (en) 2023-04-19 2024-10-24 Btl Healthcare Technologies A.S. Culture media based on protein hydrolysate and a process for preparing thereof
US12668774B2 (en) 2023-10-12 2026-06-30 Btl Healthcare Technologies A.S. Product, system and method of cell cultivation
CN121537499B (zh) * 2026-01-22 2026-05-08 中国科学院苏州纳米技术与纳米仿生研究所 一种来源于人β防御素-3的仿生肽及其制备方法和应用

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308236D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Dna vectors
WO1996041523A1 (en) 1995-06-12 1996-12-27 Yeda Research And Development Co., Ltd. Fgf9 as a specific ligand for fgfr3
US7067144B2 (en) 1998-10-20 2006-06-27 Omeros Corporation Compositions and methods for systemic inhibition of cartilage degradation
US20040109850A1 (en) 2000-12-18 2004-06-10 Neelam Jaiswal Treatment of bone disorders by modulation of fgfr3
IL142118A0 (en) 2001-03-20 2002-03-10 Prochon Biotech Ltd Method and composition for treatment of skeletal dysplasias
IL159177A0 (en) 2001-06-20 2004-06-01 Prochon Biotech Ltd Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof
JP2003104908A (ja) 2001-09-28 2003-04-09 Ichikazu Nakao 軟骨無形成症治療剤
BRPI0203172B8 (pt) 2001-09-28 2021-05-25 Nakao Kazuwa composição farmacêutica para acondroplasia
IL156495A0 (en) 2003-06-17 2004-01-04 Prochon Biotech Ltd Use of fgfr3 antagonists for treating t cell mediated diseases
AU2005216547B2 (en) 2004-02-24 2009-03-12 Allergan, Inc. Botulinum toxin screening assays
NZ565511A (en) 2005-07-22 2011-03-31 Five Prime Therapeutics Inc Compositions and methods of treating disease with FGFR fusion proteins
US8101721B2 (en) 2006-06-15 2012-01-24 Fibron Ltd. Antibodies blocking fibroblast growth factor receptor activation and methods of use thereof
US8962556B2 (en) 2006-09-28 2015-02-24 Prochon Biotech Ltd. FGF-2 variants having N-terminal deletions and increased receptor selectivity and uses thereof
WO2008133873A2 (en) 2007-04-25 2008-11-06 Aveo Pharmaceuticals, Inc. Fgf-binding fusion proteins
US8426396B2 (en) 2008-01-08 2013-04-23 Shriners Hospitals For Children Treatment for achondroplasia
WO2010002862A2 (en) 2008-07-01 2010-01-07 Aveo Pharmaceuticals, Inc. Fibroblast growth factor receptor 3 (fgfr3) binding proteins
CN102171343B (zh) 2008-08-04 2017-07-14 戊瑞治疗有限公司 Fgfr细胞外结构域酸性区突变蛋白
AR073770A1 (es) 2008-10-20 2010-12-01 Imclone Llc Anticuerpo aislado que se enlaza especificamente con, e induce la degradacion del receptor-3 del factor de crecimiento del fibroblasto humano (fgfr-3), fragmento de enlace fgfr-3 humano del mismo, composicion farmaceutica y producto que lo comprenden
ES2549769T3 (es) * 2009-03-25 2015-11-02 Genentech, Inc. Anticuerpos anti-FGFR3 y métodos que emplean los mismos
WO2011034940A1 (en) 2009-09-15 2011-03-24 Five Prime Therapeutics, Inc. Hair growth methods using fgfr4 extracellular domains
PT2498799T (pt) 2009-11-13 2016-11-04 Five Prime Therapeutics Inc Utilização de proteínas do domínio extracelular rfcf1 para tratar cancros caracterizados por mutações ativadoras dependentes de ligando em rfcf2
WO2011084711A2 (en) 2009-12-17 2011-07-14 Five Prime Therapeutics, Inc. Hair growth methods using fgfr3 extracellular domains
WO2011088196A2 (en) 2010-01-14 2011-07-21 Yale University Inhibitors of receptor tyrosine kinases (rtk) and methods of use thereof
US8481038B2 (en) 2010-11-15 2013-07-09 Five Prime Therapeutics, Inc. Treatment of cancer with elevated dosages of soluble FGFR1 fusion proteins
JP6055779B2 (ja) 2010-12-27 2016-12-27 アレクシオン ファーマシューティカルズ, インコーポレイテッド ナトリウム利尿ペプチドを含む組成物およびその使用方法
CN102219860B (zh) 2011-05-20 2012-09-12 烟台荣昌生物工程有限公司 FGFR-Fc融合蛋白及其用途
CA2853358A1 (en) 2011-10-24 2013-05-02 Halozyme, Inc. Companion diagnostic for anti-hyaluronan agent therapy and methods of use thereof
FR2984325A1 (fr) 2011-12-14 2013-06-21 Sanofi Sa Derives de pyrazolopyridine, leur procede de preparation et leur application en therapeutique
CA2880013C (en) 2012-07-24 2022-11-29 The Trustees Of Columbia University In The City Of New York Fusion proteins and methods thereof
BR112015001724A2 (pt) 2012-07-27 2018-04-03 Genentech Inc métodos de tratamento de condições relacionadas a fgfr3
EP4223770A3 (en) 2012-11-05 2023-10-18 Foundation Medicine, Inc. Novel fusion molecules and uses thereof
US20150344855A1 (en) * 2013-01-16 2015-12-03 INSERM (Institut National de la Santé et de la Recherche Médicale A Soluble Fibroblast Growth Factor Receptor 3 (FGR3) Polypeptide For Use In The Prevention Or Treatment Of Skeletal Growth Retardation Disorders
RS60593B1 (sr) 2014-01-24 2020-08-31 Ngm Biopharmaceuticals Inc Antitela koja vezuju domen 2 beta-kloto i postupci za njihovu upotrebu
CA2972865A1 (en) 2015-01-07 2016-07-14 Therachon Sas Soluble fgfr3 decoys for treating skeletal growth disorders
KR102432192B1 (ko) 2016-07-07 2022-08-12 화이자 인코포레이티드 가용성 섬유아세포 성장 인자 수용체 3(sfgfr3) 폴리펩티드 및 이의 용도
EP3684394A1 (en) 2017-09-20 2020-07-29 Pfizer Inc. Treatment of abnormal visceral fat deposition using soluble fibroblast growth factor receptor 3 (sfgfr3) polypeptides

Similar Documents

Publication Publication Date Title
RU2019100381A (ru) Полипептиды, являющиеся растворимыми рецепторами 3 фактора роста фибробластов (sfgfr3), и пути их применения
CN102718858B (zh) 胰高血糖素样肽-1类似物单体、二聚体及其制备方法与应用
HRP20221021T1 (hr) T stanični receptori specifični za kompleks tumorskog antigena ny-eso-1 sa hla-a*02
ES2389697T3 (es) Variantes de desintegrina y usos farmacéuticos de los mismos
JP2017529059A5 (enExample)
CN102643339B (zh) 一种glp-1类似物、制备方法及其应用
JP2014534265A5 (enExample)
EP3811967A1 (en) Preparation of biologically active complexes
CN112521514A (zh) 一种蛋白复合物及其制备方法和应用
US20200062811A1 (en) Yap protein inhibiting polypeptide and application thereof
AU2015356997A1 (en) CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases
CN103732240B (zh) G-csf二聚体在制备治疗神经退行性疾病药物中的应用
CN101208106B (zh) 癌症治疗剂
HUP0104126A2 (hu) Gyógyszer a csontmetabolizmus hibáira
CA3133830A1 (en) Fms-like tyrosine kinase 3 ligand (flt3l)-based chimeric proteins
RU2711161C2 (ru) Циклический с-концевой пептид ацетилхолинэстеразы в лечении или предупреждении рака или метастазирования
CA3220239A1 (en) A super-trail molecule comprising two trail trimers
JP2008509888A (ja) 上皮成長因子受容体アンタゴニストおよび使用方法
CN113355308A (zh) 用于中和冠状病毒的人工多肽、制备方法及药物组合物
JPH07503705A (ja) 医薬的リジン含有ポリペプチド組成物およびその使用法
WO1999065512A1 (fr) Compositions medicinales contenant des peptides apparentes au facteur de croissance des fibroblastes
JP4560612B2 (ja) デコリン由来ペプチド
JPH08333274A (ja) 悪性腫瘍治療用キット
JP2001523727A (ja) 造血幹細胞を可動化する方法
JP2016519110A5 (enExample)