KR102432192B1 - 가용성 섬유아세포 성장 인자 수용체 3(sfgfr3) 폴리펩티드 및 이의 용도 - Google Patents

가용성 섬유아세포 성장 인자 수용체 3(sfgfr3) 폴리펩티드 및 이의 용도 Download PDF

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KR102432192B1
KR102432192B1 KR1020197002602A KR20197002602A KR102432192B1 KR 102432192 B1 KR102432192 B1 KR 102432192B1 KR 1020197002602 A KR1020197002602 A KR 1020197002602A KR 20197002602 A KR20197002602 A KR 20197002602A KR 102432192 B1 KR102432192 B1 KR 102432192B1
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sfgfr3
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KR20190037240A (ko
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엘비르 가우지
스테파니 가르시아
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화이자 인코포레이티드
인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔)
유니베르시테 코트 다쥐르
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
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    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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KR1020197002602A 2016-07-07 2017-07-07 가용성 섬유아세포 성장 인자 수용체 3(sfgfr3) 폴리펩티드 및 이의 용도 Expired - Fee Related KR102432192B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020227027503A KR20220122762A (ko) 2016-07-07 2017-07-07 가용성 섬유아세포 성장 인자 수용체 3(sfgfr3) 폴리펩티드 및 이의 용도

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662359607P 2016-07-07 2016-07-07
US62/359,607 2016-07-07
US201762467478P 2017-03-06 2017-03-06
US62/467,478 2017-03-06
PCT/EP2017/067119 WO2018007597A1 (en) 2016-07-07 2017-07-07 Soluble fibroblast growth factor receptor 3 (sfgfr3) polypeptides and uses thereof

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KR20190037240A KR20190037240A (ko) 2019-04-05
KR102432192B1 true KR102432192B1 (ko) 2022-08-12

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KR1020227027503A Ceased KR20220122762A (ko) 2016-07-07 2017-07-07 가용성 섬유아세포 성장 인자 수용체 3(sfgfr3) 폴리펩티드 및 이의 용도

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KR102432192B1 (ko) 2016-07-07 2022-08-12 화이자 인코포레이티드 가용성 섬유아세포 성장 인자 수용체 3(sfgfr3) 폴리펩티드 및 이의 용도
EP3684394A1 (en) * 2017-09-20 2020-07-29 Pfizer Inc. Treatment of abnormal visceral fat deposition using soluble fibroblast growth factor receptor 3 (sfgfr3) polypeptides
WO2020243478A1 (en) * 2019-05-29 2020-12-03 Massachusetts Eye And Ear Infirmary Fibroblast growth factor 2 (fgf2) for treatment of human sensorineural hearing loss
US11625937B2 (en) * 2020-04-06 2023-04-11 Toyota Motor Engineering & Manufacturing North America, Inc. Methods and systems for monitoring human body weight with vehicle sensors and big data AI analytics
WO2022106976A1 (en) 2020-11-18 2022-05-27 Pfizer Inc. Stable pharmaceutical formulations of soluble fgfr3 decoys
JP2022184798A (ja) 2021-06-01 2022-12-13 ファイザー・インク ｓＦＧＦＲ３ポリペプチドを生産するための細胞培養方法
WO2024104922A1 (en) 2022-11-14 2024-05-23 Ascendis Pharma Growth Disorders A/S Method of improving skeletal muscle function
KR20250162619A (ko) 2023-03-20 2025-11-18 아센디스 파마 그로우쓰 디스오더스 에이/에스 연골무형성증을 가진 인간 대상에서의 흉요추 변형의 치료 방법
CN116284327A (zh) * 2023-03-28 2023-06-23 中国药科大学 一种靶向肿瘤的成纤维细胞生长因子19的重组蛋白及其应用
WO2024218715A1 (en) 2023-04-19 2024-10-24 Btl Healthcare Technologies A.S. Culture media based on protein hydrolysate and a process for preparing thereof
US12668774B2 (en) 2023-10-12 2026-06-30 Btl Healthcare Technologies A.S. Product, system and method of cell cultivation
CN121537499B (zh) * 2026-01-22 2026-05-08 中国科学院苏州纳米技术与纳米仿生研究所 一种来源于人β防御素-3的仿生肽及其制备方法和应用

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SG11201900074WA (en) 2019-02-27
JP7046903B2 (ja) 2022-04-04
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US10294289B2 (en) 2019-05-21
EP4122955A1 (en) 2023-01-25
JP7348980B2 (ja) 2023-09-21
HUE058734T2 (hu) 2022-09-28
RU2019100381A3 (enExample) 2020-11-23
EP3481859B1 (en) 2022-04-13
CN109715658B (zh) 2023-09-12
RU2019100381A (ru) 2020-08-11
ZA201900507B (en) 2023-04-26
CN109715658A (zh) 2019-05-03
SI3481859T1 (sl) 2022-07-29
KR20190037240A (ko) 2019-04-05
MX2018016257A (es) 2019-11-21
US11021528B2 (en) 2021-06-01
AU2022202906A1 (en) 2022-05-26
CA3029877A1 (en) 2018-01-11
WO2018007597A1 (en) 2018-01-11
AU2017294551B2 (en) 2022-03-03
US20210309718A1 (en) 2021-10-07
AU2017294551A1 (en) 2019-01-31
CA3029877C (en) 2023-07-25
US20180230197A1 (en) 2018-08-16
DK3481859T3 (da) 2022-04-25
IL264030A (en) 2019-01-31
JP2019527053A (ja) 2019-09-26
PT3481859T (pt) 2022-05-23
KR20220122762A (ko) 2022-09-02
US20200190162A1 (en) 2020-06-18
BR112019000257A2 (pt) 2019-10-01

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