JP2019525899A5 - - Google Patents

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Publication number

JP2019525899A5

JP2019525899A5 JP2018564979A JP2018564979A JP2019525899A5 JP 2019525899 A5 JP2019525899 A5 JP 2019525899A5 JP 2018564979 A JP2018564979 A JP 2018564979A JP 2018564979 A JP2018564979 A JP 2018564979A JP 2019525899 A5 JP2019525899 A5 JP 2019525899A5

Authority

JP

Japan

Prior art keywords

compound

alkyl

formula

composition

compound according

Prior art date

2017-06-02

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
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• 150000001875 compounds Chemical class 0.000 claims 27
• 239000000203 mixture Substances 0.000 claims 10
• 125000000217 alkyl group Chemical group 0.000 claims 9
• 150000001720 carbohydrates Chemical class 0.000 claims 3
• 235000005911 diet Nutrition 0.000 claims 3
• 230000037213 diet Effects 0.000 claims 3
• 150000002576 ketones Chemical class 0.000 claims 3
• 102000004169 proteins and genes Human genes 0.000 claims 3
• 108090000623 proteins and genes Proteins 0.000 claims 3
• 239000003814 drug Substances 0.000 claims 2
• 238000004519 manufacturing process Methods 0.000 claims 2
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
• 125000000547 substituted alkyl group Chemical group 0.000 claims 2
• LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims 2
• 208000009304 Acute Kidney Injury Diseases 0.000 claims 1
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• 201000010915 Glioblastoma multiforme Diseases 0.000 claims 1
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• 208000010577 Niemann-Pick disease type C Diseases 0.000 claims 1
• 208000018737 Parkinson disease Diseases 0.000 claims 1
• 208000027190 Peripheral T-cell lymphomas Diseases 0.000 claims 1
• 206010035226 Plasma cell myeloma Diseases 0.000 claims 1
• 206010060862 Prostate cancer Diseases 0.000 claims 1
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• 208000033626 Renal failure acute Diseases 0.000 claims 1
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• 208000031673 T-Cell Cutaneous Lymphoma Diseases 0.000 claims 1
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• 208000007930 Type C Niemann-Pick Disease Diseases 0.000 claims 1
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• 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 1
• 230000007574 infarction Effects 0.000 claims 1
• 235000020887 ketogenic diet Nutrition 0.000 claims 1
• 208000002780 macular degeneration Diseases 0.000 claims 1
• 208000020968 mature T-cell and NK-cell non-Hodgkin lymphoma Diseases 0.000 claims 1
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• 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
• 239000008194 pharmaceutical composition Substances 0.000 claims 1
• 208000025638 primary cutaneous T-cell non-Hodgkin lymphoma Diseases 0.000 claims 1
• 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
• 150000003839 salts Chemical class 0.000 claims 1
• 239000012453 solvate Substances 0.000 claims 1
• 239000013589 supplement Substances 0.000 claims 1
• 230000009529 traumatic brain injury Effects 0.000 claims 1