JP2015531386A5 - - Google Patents
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- Publication number
- JP2015531386A5 JP2015531386A5 JP2015535002A JP2015535002A JP2015531386A5 JP 2015531386 A5 JP2015531386 A5 JP 2015531386A5 JP 2015535002 A JP2015535002 A JP 2015535002A JP 2015535002 A JP2015535002 A JP 2015535002A JP 2015531386 A5 JP2015531386 A5 JP 2015531386A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- och
- substituted
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *N1CCCC1 Chemical compound *N1CCCC1 0.000 description 11
- NBRPDWTZNNSUMU-UHFFFAOYSA-N CC(NC(CC(N)N1)C1=O)=O Chemical compound CC(NC(CC(N)N1)C1=O)=O NBRPDWTZNNSUMU-UHFFFAOYSA-N 0.000 description 1
- SXZQFWNGSMIHQZ-MQBBKVSDSA-N CC(c(cc1)ccc1O[C@H](CC1)CN1c(cc1)ccc1OCC1CC1)NC(Cc1cncnc1)=O Chemical compound CC(c(cc1)ccc1O[C@H](CC1)CN1c(cc1)ccc1OCC1CC1)NC(Cc1cncnc1)=O SXZQFWNGSMIHQZ-MQBBKVSDSA-N 0.000 description 1
- FDSXRSHMDXIVJH-UHFFFAOYSA-N CCC(COI)(F)F Chemical compound CCC(COI)(F)F FDSXRSHMDXIVJH-UHFFFAOYSA-N 0.000 description 1
- QKSCWLACFHQUEZ-SJDLUZLQSA-N C[C@@H](c(cc1)ccc1OC1CCC(Cc(cc2)ccc2OCC(C)(F)F)CC1)NC(C)=O Chemical compound C[C@@H](c(cc1)ccc1OC1CCC(Cc(cc2)ccc2OCC(C)(F)F)CC1)NC(C)=O QKSCWLACFHQUEZ-SJDLUZLQSA-N 0.000 description 1
- BQYIKOFKDONVNP-HNAYVOBHSA-N C[C@@H](c(cc1)ccc1O[C@H](CC1)CN1c(cc1OCCCOc1c1)c1F)NC(C)=O Chemical compound C[C@@H](c(cc1)ccc1O[C@H](CC1)CN1c(cc1OCCCOc1c1)c1F)NC(C)=O BQYIKOFKDONVNP-HNAYVOBHSA-N 0.000 description 1
- ZEJZJYKHHGUODC-UHFFFAOYSA-N C[n](cc[n]1nc2)c1c2N Chemical compound C[n](cc[n]1nc2)c1c2N ZEJZJYKHHGUODC-UHFFFAOYSA-N 0.000 description 1
- RSDRZFCZRBPZCJ-UHFFFAOYSA-N FC(CCOI)F Chemical compound FC(CCOI)F RSDRZFCZRBPZCJ-UHFFFAOYSA-N 0.000 description 1
- ATHREQFBKGWRAK-UHFFFAOYSA-N FC1(C(COI)C1)F Chemical compound FC1(C(COI)C1)F ATHREQFBKGWRAK-UHFFFAOYSA-N 0.000 description 1
- URKYFRSLKUNMFG-UHFFFAOYSA-N NC(CC1)NC1=O Chemical compound NC(CC1)NC1=O URKYFRSLKUNMFG-UHFFFAOYSA-N 0.000 description 1
- QRSZMEQQBAGKPH-UHFFFAOYSA-N Nc1c2nccc[n]2nc1 Chemical compound Nc1c2nccc[n]2nc1 QRSZMEQQBAGKPH-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12187591 | 2012-10-08 | ||
| EP12187591.8 | 2012-10-08 | ||
| PCT/EP2013/070507 WO2014056771A1 (en) | 2012-10-08 | 2013-10-02 | New pyrrolidine derivatives and their use as acetyl-coa carboxylase inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015531386A JP2015531386A (ja) | 2015-11-02 |
| JP2015531386A5 true JP2015531386A5 (enExample) | 2016-11-24 |
| JP6244591B2 JP6244591B2 (ja) | 2017-12-13 |
Family
ID=47143526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015535002A Expired - Fee Related JP6244591B2 (ja) | 2012-10-08 | 2013-10-02 | 新規ピロリジン誘導体及びそれらのアセチルｃｏａカルボキシラーゼ阻害薬としての使用 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9169205B2 (enExample) |
| EP (1) | EP2903982B1 (enExample) |
| JP (1) | JP6244591B2 (enExample) |
| WO (1) | WO2014056771A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6378752B2 (ja) * | 2013-05-17 | 2018-08-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ピロリジン誘導体、その医薬組成物及び使用 |
| WO2015056782A1 (ja) | 2013-10-17 | 2015-04-23 | 塩野義製薬株式会社 | 新規アルキレン誘導体 |
| WO2017066633A1 (en) | 2015-10-16 | 2017-04-20 | Eisai R&D Management Co., Ltd. | Ep4 antagonists |
| KR102224550B1 (ko) * | 2018-04-02 | 2021-03-09 | 울산대학교 산학협력단 | 신규한 에테르 화합물, 및 광 산화환원 촉매를 이용하여 활성화된 알켄 화합물로부터 에테르 화합물을 제조하는 방법 |
| WO2023090411A1 (ja) | 2021-11-19 | 2023-05-25 | 塩野義製薬株式会社 | 心疾患または骨格筋の疾患の治療用医薬 |
| WO2025155669A1 (en) * | 2024-01-17 | 2025-07-24 | The Jackson Laboratory | Trpc3 inhibitors and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009521448A (ja) * | 2005-12-21 | 2009-06-04 | シェーリング コーポレイション | ヒスタミンｈ３アンタゴニストとして有用なフェノキシピペリジンおよびそのアナログ |
| KR20100120689A (ko) * | 2008-02-22 | 2010-11-16 | 아이알엠 엘엘씨 | Ｇｐｒ119 활성의 조절제로서의 화합물 및 조성물 |
| US9006450B2 (en) | 2010-07-01 | 2015-04-14 | Boehringer Ingelheim International Gmbh | Compounds, pharmaceutical compositions and uses thereof |
| WO2012090219A2 (en) | 2010-12-31 | 2012-07-05 | Jubilant Biosys Ltd. | Thiazole compounds useful as acetyl-coa carboxylase (acc) inhibitors |
-
2013
- 2013-10-01 US US14/043,128 patent/US9169205B2/en active Active
- 2013-10-02 EP EP13771485.3A patent/EP2903982B1/en active Active
- 2013-10-02 JP JP2015535002A patent/JP6244591B2/ja not_active Expired - Fee Related
- 2013-10-02 WO PCT/EP2013/070507 patent/WO2014056771A1/en not_active Ceased
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