JP2019523772A5 - - Google Patents
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- JP2019523772A5 JP2019523772A5 JP2018565715A JP2018565715A JP2019523772A5 JP 2019523772 A5 JP2019523772 A5 JP 2019523772A5 JP 2018565715 A JP2018565715 A JP 2018565715A JP 2018565715 A JP2018565715 A JP 2018565715A JP 2019523772 A5 JP2019523772 A5 JP 2019523772A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610432126.5 | 2016-06-16 | ||
| CN201610432126.5A CN107513069A (zh) | 2016-06-16 | 2016-06-16 | 手性吡咯并嘧啶化合物的制备方法 |
| PCT/CN2017/088421 WO2017215627A1 (zh) | 2016-06-16 | 2017-06-15 | 手性吡咯并嘧啶化合物的制备方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019523772A JP2019523772A (ja) | 2019-08-29 |
| JP2019523772A5 true JP2019523772A5 (enExample) | 2020-05-21 |
| JP6998896B2 JP6998896B2 (ja) | 2022-02-04 |
Family
ID=60663390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018565715A Active JP6998896B2 (ja) | 2016-06-16 | 2017-06-15 | キラルピロロピリミジン化合物の製造方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10766901B2 (enExample) |
| EP (1) | EP3473625B1 (enExample) |
| JP (1) | JP6998896B2 (enExample) |
| CN (3) | CN107513069A (enExample) |
| ES (1) | ES2877678T3 (enExample) |
| WO (1) | WO2017215627A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019413421B9 (en) * | 2018-12-24 | 2025-02-20 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Treatment use of pyrrolopyrimidine compound, and solid pharmaceutical composition of pyrrolopyrimidine compound |
| EP4119562A4 (en) * | 2020-03-09 | 2024-04-24 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | USE OF A PYRROLOPYRIMIDINE COMPOUND FOR THE TREATMENT OF HEMOPHAGOCYTIC SYNDROME |
| WO2022040180A1 (en) | 2020-08-18 | 2022-02-24 | Incyte Corporation | Process and intermediates for preparing a jak inhibitor |
| US11897889B2 (en) | 2020-08-18 | 2024-02-13 | Incyte Corporation | Process and intermediates for preparing a JAK1 inhibitor |
| CN114085224A (zh) * | 2020-08-25 | 2022-02-25 | 北京普祺医药科技有限公司 | 一种吡咯并嘧啶化合物的制备方法 |
| EP4361152A4 (en) | 2021-06-21 | 2025-05-28 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Use of a pyrrholopyrimidine compound and pharmaceutical composition thereof for the treatment of chronic graft-versus-host disease |
| US12071439B2 (en) | 2021-07-12 | 2024-08-27 | Incyte Corporation | Process and intermediates for preparing a JAK inhibitor |
| CN120459106A (zh) | 2022-03-21 | 2025-08-12 | 正大天晴药业集团股份有限公司 | 吡咯并嘧啶化合物治疗中高危骨髓纤维化的用途 |
| WO2024027790A1 (zh) | 2022-08-04 | 2024-02-08 | 正大天晴药业集团股份有限公司 | 吡咯并嘧啶化合物治疗急性移植物抗宿主病的用途 |
| WO2024042448A1 (en) * | 2022-08-22 | 2024-02-29 | Granules India Limited | An improved process for the preparation of ruxolitinib |
| CN120882718A (zh) * | 2023-03-17 | 2025-10-31 | 北京普祺医药科技股份有限公司 | 吡咯并嘧啶化合物或其可药用盐的制备方法 |
| WO2024230727A1 (zh) * | 2023-05-09 | 2024-11-14 | 正大天晴药业集团股份有限公司 | 一种吡咯并[2,3-c]吡啶酮化合物的联用药物组合物及其用途 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5616499A (en) * | 1979-07-19 | 1981-02-17 | Yamasa Shoyu Co Ltd | 6-c-purine nucleoside derivative and its preparation |
| JPS5841897A (ja) * | 1981-09-04 | 1983-03-11 | Yamasa Shoyu Co Ltd | ６−（４−ピラゾリル）プリンリボヌクレオシド誘導体およびその製造法 |
| PA8474101A1 (es) * | 1998-06-19 | 2000-09-29 | Pfizer Prod Inc | Compuestos de pirrolo [2,3-d] pirimidina |
| US20050008640A1 (en) * | 2003-04-23 | 2005-01-13 | Wendy Waegell | Method of treating transplant rejection |
| TWI630207B (zh) | 2005-12-13 | 2018-07-21 | 英塞特控股公司 | 作為傑納斯激酶（ＪＡＮＵＳ ＫＩＮＡＳＥ）抑制劑之經雜芳基取代之吡咯并〔２，３-ｂ〕吡啶及吡咯并〔２，３-ｂ〕嘧啶 |
| TWI665200B (zh) * | 2009-01-15 | 2019-07-11 | 英塞特公司 | 製造ｊａｋ抑制劑之方法及相關中間化合物 |
| AR078012A1 (es) | 2009-09-01 | 2011-10-05 | Incyte Corp | Derivados heterociclicos de las pirazol-4-il- pirrolo (2,3-d) pirimidinas como inhibidores de la quinasa janus |
| CN103848810A (zh) | 2012-11-30 | 2014-06-11 | 北京赛林泰医药技术有限公司 | 鲁顿酪氨酸激酶抑制剂 |
| CN103739607A (zh) * | 2014-01-22 | 2014-04-23 | 无锡方圆环球显示技术股份有限公司 | 一种基于三并咔唑多臂结构红光材料及其制备方法与应用 |
| EP3152214B1 (en) * | 2014-06-04 | 2020-01-29 | Merck Sharp & Dohme Corp. | Imidazo-pyrazine derivatives useful as soluble guanylate cyclase activators |
| CN105218548A (zh) | 2014-06-09 | 2016-01-06 | 上海海和药物研究开发有限公司 | 一种新型杂环化合物及其制备方法和作为激酶抑制剂的用途 |
| CN105315286B (zh) * | 2014-07-30 | 2018-08-17 | 连云港润众制药有限公司 | 西格列汀的制备 |
| CN105777754B (zh) * | 2014-12-16 | 2019-07-26 | 北京赛林泰医药技术有限公司 | 吡咯并嘧啶化合物 |
| CN107759600A (zh) | 2016-06-16 | 2018-03-06 | 正大天晴药业集团股份有限公司 | 作为jak抑制剂的吡咯并嘧啶化合物的结晶 |
-
2016
- 2016-06-16 CN CN201610432126.5A patent/CN107513069A/zh active Pending
-
2017
- 2017-06-15 CN CN202010744086.4A patent/CN111875607B/zh active Active
- 2017-06-15 JP JP2018565715A patent/JP6998896B2/ja active Active
- 2017-06-15 WO PCT/CN2017/088421 patent/WO2017215627A1/zh not_active Ceased
- 2017-06-15 ES ES17812738T patent/ES2877678T3/es active Active
- 2017-06-15 US US16/309,882 patent/US10766901B2/en active Active
- 2017-06-15 CN CN201780037151.6A patent/CN109311892B/zh active Active
- 2017-06-15 EP EP17812738.7A patent/EP3473625B1/en active Active
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