JP2018522012A5 - - Google Patents

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Publication number
JP2018522012A5
JP2018522012A5 JP2018502212A JP2018502212A JP2018522012A5 JP 2018522012 A5 JP2018522012 A5 JP 2018522012A5 JP 2018502212 A JP2018502212 A JP 2018502212A JP 2018502212 A JP2018502212 A JP 2018502212A JP 2018522012 A5 JP2018522012 A5 JP 2018522012A5
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JP
Japan
Prior art keywords
formula
methylpropyloxy
fluorophenylmethyl
methylpiperidin
carbamide
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JP2018502212A
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English (en)
Japanese (ja)
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JP2018522012A (ja
JP6850282B2 (ja
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Priority claimed from PCT/US2016/042933 external-priority patent/WO2017015272A1/en
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Publication of JP2018522012A5 publication Critical patent/JP2018522012A5/ja
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JP2018502212A 2015-07-20 2016-07-19 N−(4−フルオロベンジル)−n−(1−メチルピペリジン−4−イル)−n’−(4−(2−メチルプロピルオキシ)フェニルメチル)カルバミドならびにその酒石酸塩および多形形態cを調製する方法 Active JP6850282B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562194725P 2015-07-20 2015-07-20
US62/194,725 2015-07-20
PCT/US2016/042933 WO2017015272A1 (en) 2015-07-20 2016-07-19 Methods for preparing n-(4-fluorobenzyl)-n-(1-methylpiperidin-4-yl)-n'-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and polymorphic form c

Publications (3)

Publication Number Publication Date
JP2018522012A JP2018522012A (ja) 2018-08-09
JP2018522012A5 true JP2018522012A5 (enExample) 2019-08-08
JP6850282B2 JP6850282B2 (ja) 2021-03-31

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JP2018502212A Active JP6850282B2 (ja) 2015-07-20 2016-07-19 N−(4−フルオロベンジル)−n−(1−メチルピペリジン−4−イル)−n’−(4−(2−メチルプロピルオキシ)フェニルメチル)カルバミドならびにその酒石酸塩および多形形態cを調製する方法

Country Status (13)

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US (4) US10597363B2 (enExample)
EP (1) EP3325444B1 (enExample)
JP (1) JP6850282B2 (enExample)
CN (1) CN107848972B (enExample)
CA (1) CA2992728A1 (enExample)
DK (1) DK3325444T3 (enExample)
ES (1) ES2890492T3 (enExample)
HU (1) HUE055763T2 (enExample)
IL (1) IL256998B (enExample)
PL (1) PL3325444T3 (enExample)
PT (1) PT3325444T (enExample)
SI (1) SI3325444T1 (enExample)
WO (1) WO2017015272A1 (enExample)

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WO2019040106A2 (en) * 2017-08-21 2019-02-28 Acadia Pharmaceuticals Inc. COMPOUNDS, RELATED SALTS AND METHODS FOR THE TREATMENT OF DISEASES
EP3672960A2 (en) * 2017-08-21 2020-07-01 Acadia Pharmaceuticals Inc. Compounds, salts thereof and their use for the treatment of diseases
EP3675827A1 (en) 2017-08-30 2020-07-08 Acadia Pharmaceuticals Inc. Formulations of pimavanserin
CN110054583A (zh) * 2018-01-19 2019-07-26 广东东阳光药业有限公司 一种制备哌马色林或其盐的方法
CA3097672A1 (en) 2018-04-26 2019-10-31 Olon S.P.A. Method for the preparation of pimavanserin base
CN110894186B (zh) * 2018-09-12 2022-05-24 浙江京新药业股份有限公司 匹莫范色林及其中间体的制备方法
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CN111320569B (zh) * 2018-12-17 2022-03-08 江苏艾立康医药科技有限公司 一种哌马色林固态中间体的制备方法
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CN116496496B (zh) * 2023-04-27 2024-11-05 中国石油大学(华东) 一种基于三嗪共价框架材料(CTFs)制备单位点催化剂的制备方法

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