JP2019519492A5 - - Google Patents
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- JP2019519492A5 JP2019519492A5 JP2018558733A JP2018558733A JP2019519492A5 JP 2019519492 A5 JP2019519492 A5 JP 2019519492A5 JP 2018558733 A JP2018558733 A JP 2018558733A JP 2018558733 A JP2018558733 A JP 2018558733A JP 2019519492 A5 JP2019519492 A5 JP 2019519492A5
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- 239000012634 fragment Substances 0.000 claims description 113
- 239000000427 antigen Substances 0.000 claims description 112
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- 108010021064 CTLA-4 Antigen Proteins 0.000 claims description 5
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- 101001012157 Homo sapiens Receptor tyrosine-protein kinase erbB-2 Proteins 0.000 description 3
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- 102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 description 3
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- YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 description 3
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662333643P | 2016-05-09 | 2016-05-09 | |
| US62/333,643 | 2016-05-09 | ||
| PCT/US2017/031791 WO2017196867A1 (en) | 2016-05-09 | 2017-05-09 | Anti-pd-l1 antibodies |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019519492A JP2019519492A (ja) | 2019-07-11 |
| JP2019519492A5 true JP2019519492A5 (OSRAM) | 2020-06-18 |
| JP6979971B2 JP6979971B2 (ja) | 2021-12-15 |
Family
ID=58710168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018558733A Active JP6979971B2 (ja) | 2016-05-09 | 2017-05-09 | 抗ｐｄ−ｌ１抗体 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US10954302B2 (OSRAM) |
| EP (1) | EP3455257B1 (OSRAM) |
| JP (1) | JP6979971B2 (OSRAM) |
| KR (1) | KR102343742B1 (OSRAM) |
| CN (1) | CN109311985B (OSRAM) |
| AU (1) | AU2017264683B2 (OSRAM) |
| CA (1) | CA3021669A1 (OSRAM) |
| DK (1) | DK3455257T3 (OSRAM) |
| ES (1) | ES2899361T3 (OSRAM) |
| HU (1) | HUE055972T2 (OSRAM) |
| IL (1) | IL262295B2 (OSRAM) |
| PL (1) | PL3455257T3 (OSRAM) |
| PT (1) | PT3455257T (OSRAM) |
| SG (1) | SG11201809336QA (OSRAM) |
| WO (1) | WO2017196867A1 (OSRAM) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105722855B (zh) | 2013-09-05 | 2021-04-23 | Igm生物科学股份有限公司 | 恒定链经修饰的双特异性五价和六价Ig-M抗体 |
| DK3105250T3 (da) | 2014-02-10 | 2020-09-28 | Igm Biosciences Inc | Multispecifikke iga-bindingsmolekyler |
| GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
| HUE042829T2 (hu) | 2014-04-03 | 2019-07-29 | Igm Biosciences Inc | Módosított J-lánc |
| CA2972990A1 (en) | 2015-01-20 | 2016-07-28 | Beatrice Tien-Yi WANG | Tumor necrosis factor (tnf) superfamily receptor binding molecules and uses thereof |
| PL3265575T3 (pl) | 2015-03-04 | 2021-11-29 | Igm Biosciences, Inc. | Cząsteczki wiążące CD20 i ich zastosowania |
| JP6826055B2 (ja) | 2015-03-13 | 2021-02-03 | サイトメックス セラピューティクス インコーポレイテッド | 抗ｐｄｌ１抗体、活性化可能抗ｐｄｌ１抗体、およびその使用方法 |
| CA2980751A1 (en) | 2015-03-25 | 2016-09-29 | Stephen F. Carroll | Multi-valent hepatitis b virus antigen binding molecules and uses thereof |
| JP6811723B2 (ja) | 2015-04-17 | 2021-01-13 | アイジーエム バイオサイエンシズ インコーポレイテッド | 多価ヒト免疫不全ウイルス抗原結合分子およびその使用方法 |
| AU2016329197B2 (en) | 2015-09-30 | 2021-01-21 | Igm Biosciences, Inc. | Binding molecules with modified J-chain |
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| WO2017220989A1 (en) | 2016-06-20 | 2017-12-28 | Kymab Limited | Anti-pd-l1 and il-2 cytokines |
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| JP2021510078A (ja) * | 2018-01-10 | 2021-04-15 | 江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司Ｊｉａｎｇｓｕ Ｈｅｎｇｒｕｉ Ｍｅｄｉｃｉｎｅ Ｃｏ．， Ｌｔｄ． | Ｐｄ−ｌ１抗体、その抗原結合フラグメント、及びその製薬学的使用 |
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| BR112022002780A2 (pt) * | 2019-08-15 | 2022-05-10 | Igm Biosciences Inc | Moléculas de ligação multiméricas imunoestimulatórias |
| CN110746493A (zh) * | 2019-09-06 | 2020-02-04 | 中国药科大学 | 一种pd-l1拮抗剂多肽及其应用 |
| CN113121686B (zh) * | 2019-12-31 | 2025-12-02 | 迈威(上海)生物科技股份有限公司 | 抗pd-l1抗体及其应用 |
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| CN113754775A (zh) * | 2020-06-02 | 2021-12-07 | 三生国健药业（上海）股份有限公司 | 一种抗pd-l1和her2的双特异性抗体 |
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| AU2021315513A1 (en) * | 2020-07-27 | 2023-03-02 | Igm Biosciences, Inc. | Multimeric coronavirus binding molecules and uses thereof |
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| CN113943371B (zh) * | 2021-11-01 | 2023-05-05 | 达石药业(广东)有限公司 | 一种抗her2/抗pd-l1双功能抗体及其应用 |
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| KR20250022049A (ko) | 2022-06-07 | 2025-02-14 | 제넨테크, 인크. | 항-pd-l1 길항제 및 항-tigit 길항제 항체를 포함하는, 폐암 치료의 효율을 결정하는 방법 |
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| PL3265575T3 (pl) | 2015-03-04 | 2021-11-29 | Igm Biosciences, Inc. | Cząsteczki wiążące CD20 i ich zastosowania |
| CA2980751A1 (en) | 2015-03-25 | 2016-09-29 | Stephen F. Carroll | Multi-valent hepatitis b virus antigen binding molecules and uses thereof |
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| MX2019011986A (es) | 2017-04-07 | 2019-11-07 | Igm Biosciences Inc | Regiones constantes de igm humana modificadas para la modulacion de la funcion efectora de la citolisis dependiente de complemento referencia cruzada a solicitudes relacionadas. |
| US20200392239A1 (en) | 2018-02-26 | 2020-12-17 | Igm Biosciences, Inc. | Use of a multimeric anti-dr5 binding molecule in combination with a chemotherapeutic agent for treating cancer |
| CA3091144A1 (en) | 2018-03-01 | 2019-09-06 | Igm Biosciences, Inc. | Igm fc and j-chain mutations that affect igm serum half-life |
| AU2019368289A1 (en) | 2018-10-23 | 2021-04-29 | Igm Biosciences, Inc. | Multivalent IgM- and IgA-Fc-based binding molecules |
| WO2020163646A1 (en) | 2019-02-08 | 2020-08-13 | Igm Biosciences, Inc. | Anti-gitr antigen-binding domains and uses thereof |
-
2017
- 2017-05-09 SG SG11201809336QA patent/SG11201809336QA/en unknown
- 2017-05-09 DK DK17724263.3T patent/DK3455257T3/da active
- 2017-05-09 EP EP17724263.3A patent/EP3455257B1/en active Active
- 2017-05-09 AU AU2017264683A patent/AU2017264683B2/en not_active Ceased
- 2017-05-09 IL IL262295A patent/IL262295B2/en unknown
- 2017-05-09 WO PCT/US2017/031791 patent/WO2017196867A1/en not_active Ceased
- 2017-05-09 HU HUE17724263A patent/HUE055972T2/hu unknown
- 2017-05-09 PT PT177242633T patent/PT3455257T/pt unknown
- 2017-05-09 PL PL17724263T patent/PL3455257T3/pl unknown
- 2017-05-09 US US16/098,479 patent/US10954302B2/en active Active
- 2017-05-09 CA CA3021669A patent/CA3021669A1/en active Pending
- 2017-05-09 ES ES17724263T patent/ES2899361T3/es active Active
- 2017-05-09 CN CN201780027997.1A patent/CN109311985B/zh active Active
- 2017-05-09 JP JP2018558733A patent/JP6979971B2/ja active Active
- 2017-05-09 KR KR1020187035104A patent/KR102343742B1/ko active Active
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2021
- 2021-02-10 US US17/172,790 patent/US20210163600A1/en not_active Abandoned
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2023
- 2023-09-07 US US18/463,194 patent/US20240002514A1/en active Pending
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