JP2019517463A5 - - Google Patents

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JP2019517463A5
JP2019517463A5 JP2018559929A JP2018559929A JP2019517463A5 JP 2019517463 A5 JP2019517463 A5 JP 2019517463A5 JP 2018559929 A JP2018559929 A JP 2018559929A JP 2018559929 A JP2018559929 A JP 2018559929A JP 2019517463 A5 JP2019517463 A5 JP 2019517463A5
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methyl
oxopyridin
methoxypyridin
methoxymethyl
pyrazole
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JP2018559929A
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JP6957516B2 (ja
JP2019517463A (ja
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JP2018559929A 2016-06-01 2017-06-01 カリクレインインヒビターとしての、ｎ−［（３−フルオロ−４−メトキシピリジン−２−イル）メチル］−３−（メトキシメチル）−１−（｛４−［（２−オキソピリジン−１−イル）メチル］フェニル｝メチル）ピラゾール−４−カルボキサミドの多形体 Active JP6957516B2 (ja)

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JP2021164519A JP7383676B2 (ja) 2016-06-01 2021-10-06 カリクレインインヒビターとしての、ｎ－［（３－フルオロ－４－メトキシピリジン－２－イル）メチル］－３－（メトキシメチル）－１－（｛４－［（２－オキソピリジン－１－イル）メチル］フェニル｝メチル）ピラゾール－４－カルボキサミドの多形体

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US201662344059P 2016-06-01 2016-06-01
US62/344,059 2016-06-01
GB1609607.5 2016-06-01
GBGB1609607.5A GB201609607D0 (en) 2016-06-01 2016-06-01 Polymorphs of N-(3-Fluoro-4-methoxypyridin-2-yl)methyl)-3-(methoxymethyl)-1-({4-((2-oxopy ridin-1-yl)methyl)phenyl}methyl)pyrazole-4-carboxamide and salts
PCT/GB2017/051579 WO2017208005A1 (en) 2016-06-01 2017-06-01 Polymorphs of n-[(3-fluoro-4-methoxypyridin-2-yl)methyl]-3-(methoxymethyl)-1 -({4-[2-oxopyridin-1 -yl)methyl]phenyl} methyl) pyrazole -4-carboxamide as kallikrein inhibitors

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JP2021164519A Division JP7383676B2 (ja) 2016-06-01 2021-10-06 カリクレインインヒビターとしての、ｎ－［（３－フルオロ－４－メトキシピリジン－２－イル）メチル］－３－（メトキシメチル）－１－（｛４－［（２－オキソピリジン－１－イル）メチル］フェニル｝メチル）ピラゾール－４－カルボキサミドの多形体

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JP2019517463A JP2019517463A (ja) 2019-06-24
JP2019517463A5 true JP2019517463A5 (cg-RX-API-DMAC7.html) 2020-07-09
JP6957516B2 JP6957516B2 (ja) 2021-11-02

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JP2018559929A Active JP6957516B2 (ja) 2016-06-01 2017-06-01 カリクレインインヒビターとしての、ｎ−［（３−フルオロ−４−メトキシピリジン−２−イル）メチル］−３−（メトキシメチル）−１−（｛４−［（２−オキソピリジン−１−イル）メチル］フェニル｝メチル）ピラゾール−４−カルボキサミドの多形体
JP2021164519A Active JP7383676B2 (ja) 2016-06-01 2021-10-06 カリクレインインヒビターとしての、ｎ－［（３－フルオロ－４－メトキシピリジン－２－イル）メチル］－３－（メトキシメチル）－１－（｛４－［（２－オキソピリジン－１－イル）メチル］フェニル｝メチル）ピラゾール－４－カルボキサミドの多形体

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Country Status (26)

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US (3) US11230537B2 (cg-RX-API-DMAC7.html)
EP (2) EP4151630A1 (cg-RX-API-DMAC7.html)
JP (2) JP6957516B2 (cg-RX-API-DMAC7.html)
KR (1) KR102425918B1 (cg-RX-API-DMAC7.html)
CN (1) CN109379891B (cg-RX-API-DMAC7.html)
AU (1) AU2017273136B2 (cg-RX-API-DMAC7.html)
BR (1) BR112018073521B1 (cg-RX-API-DMAC7.html)
CA (1) CA3025720A1 (cg-RX-API-DMAC7.html)
DK (1) DK3464265T3 (cg-RX-API-DMAC7.html)
ES (1) ES2927779T3 (cg-RX-API-DMAC7.html)
GB (1) GB201609607D0 (cg-RX-API-DMAC7.html)
HR (1) HRP20221019T1 (cg-RX-API-DMAC7.html)
HU (1) HUE059165T2 (cg-RX-API-DMAC7.html)
IL (1) IL263222B (cg-RX-API-DMAC7.html)
LT (1) LT3464265T (cg-RX-API-DMAC7.html)
MA (1) MA45130B1 (cg-RX-API-DMAC7.html)
MD (1) MD3464265T2 (cg-RX-API-DMAC7.html)
MX (1) MX386113B (cg-RX-API-DMAC7.html)
PL (1) PL3464265T3 (cg-RX-API-DMAC7.html)
PT (1) PT3464265T (cg-RX-API-DMAC7.html)
RS (1) RS63604B1 (cg-RX-API-DMAC7.html)
RU (1) RU2756273C2 (cg-RX-API-DMAC7.html)
SI (1) SI3464265T1 (cg-RX-API-DMAC7.html)
SM (1) SMT202200341T1 (cg-RX-API-DMAC7.html)
WO (1) WO2017208005A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201808638B (cg-RX-API-DMAC7.html)

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EP4010333A1 (en) 2019-08-09 2022-06-15 Kalvista Pharmaceuticals Limited Plasma kallikrein inhibitors
CN114269430A (zh) 2019-08-21 2022-04-01 卡尔维斯塔制药有限公司 酶抑制剂
EP4017850A1 (en) 2019-08-21 2022-06-29 Kalvista Pharmaceuticals Limited Enzyme inhibitors
PH12022550124A1 (en) 2019-08-21 2022-11-14 Kalvista Pharmaceuticals Ltd Enzyme inhibitors
BR112022001341A2 (pt) 2019-08-21 2022-03-22 Kalvista Pharmaceuticals Ltd Inibidores de enzima
GB201918994D0 (en) 2019-12-20 2020-02-05 Kalvista Pharmaceuticals Ltd Treatments of diabetic macular edema and impaired visual acuity

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