JP2019513755A5 - - Google Patents

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Publication number
JP2019513755A5
JP2019513755A5 JP2018552900A JP2018552900A JP2019513755A5 JP 2019513755 A5 JP2019513755 A5 JP 2019513755A5 JP 2018552900 A JP2018552900 A JP 2018552900A JP 2018552900 A JP2018552900 A JP 2018552900A JP 2019513755 A5 JP2019513755 A5 JP 2019513755A5
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JP
Japan
Prior art keywords
carbonyl
oxy
fluoro
hexane
amino
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Application number
JP2018552900A
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English (en)
Japanese (ja)
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JP7045321B2 (ja
JP2019513755A (ja
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Priority claimed from PCT/JP2017/016125 external-priority patent/WO2017183734A1/en
Publication of JP2019513755A publication Critical patent/JP2019513755A/ja
Publication of JP2019513755A5 publication Critical patent/JP2019513755A5/ja
Application granted granted Critical
Publication of JP7045321B2 publication Critical patent/JP7045321B2/ja
Active legal-status Critical Current
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JP2018552900A 2016-04-18 2017-04-18 アミノ酸誘導体のプロドラッグ Active JP7045321B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2016083147 2016-04-18
JP2016083147 2016-04-18
PCT/JP2017/016125 WO2017183734A1 (en) 2016-04-18 2017-04-18 Prodrug of amino acid derivative

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020212361A Division JP2021063095A (ja) 2016-04-18 2020-12-22 アミノ酸誘導体のプロドラッグ

Publications (3)

Publication Number Publication Date
JP2019513755A JP2019513755A (ja) 2019-05-30
JP2019513755A5 true JP2019513755A5 (https=) 2019-11-07
JP7045321B2 JP7045321B2 (ja) 2022-03-31

Family

ID=58737797

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018552900A Active JP7045321B2 (ja) 2016-04-18 2017-04-18 アミノ酸誘導体のプロドラッグ
JP2020212361A Withdrawn JP2021063095A (ja) 2016-04-18 2020-12-22 アミノ酸誘導体のプロドラッグ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2020212361A Withdrawn JP2021063095A (ja) 2016-04-18 2020-12-22 アミノ酸誘導体のプロドラッグ

Country Status (29)

Country Link
US (2) US10464884B2 (https=)
EP (1) EP3445743B1 (https=)
JP (2) JP7045321B2 (https=)
KR (1) KR102444718B1 (https=)
CN (1) CN109071418B (https=)
AU (1) AU2017254266B2 (https=)
BR (1) BR112018069959B1 (https=)
CA (1) CA3019097C (https=)
CY (1) CY1124574T1 (https=)
DK (1) DK3445743T3 (https=)
ES (1) ES2886442T3 (https=)
HR (1) HRP20211277T1 (https=)
HU (1) HUE056046T2 (https=)
IL (1) IL262233B (https=)
LT (1) LT3445743T (https=)
MX (1) MX379567B (https=)
MY (1) MY195208A (https=)
NZ (1) NZ747061A (https=)
PH (1) PH12018502211A1 (https=)
PL (1) PL3445743T3 (https=)
PT (1) PT3445743T (https=)
RS (1) RS62515B1 (https=)
RU (1) RU2739318C2 (https=)
SG (2) SG11201808387PA (https=)
SI (1) SI3445743T1 (https=)
SM (1) SMT202100601T1 (https=)
TW (1) TWI738767B (https=)
WO (1) WO2017183734A1 (https=)
ZA (1) ZA201806444B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3445743B1 (en) * 2016-04-18 2021-08-04 Taisho Pharmaceutical Co., Ltd. Prodrug of amino acid derivative
JP7314494B2 (ja) * 2017-10-17 2023-07-26 大正製薬株式会社 アミノ酸誘導体のプロドラッグを含有する医薬
ES2970042T3 (es) * 2018-04-24 2024-05-24 Viiv Healthcare Uk No 5 Ltd Compuestos con actividad inhibidora de la maduración del VIH
CN109180712B (zh) * 2018-08-08 2020-12-25 南京医科大学 一类2-茨醇的芳基硼酸酯衍生物及其应用
CN108948077B (zh) * 2018-08-09 2020-10-13 东华理工大学 一种α-磷酰化的α-氨基酸酯类化合物及其合成方法
JPWO2022114135A1 (https=) * 2020-11-26 2022-06-02
CN112409443B (zh) * 2021-01-25 2021-04-27 潍坊科技学院 一种脯氨酸茨醇衍生物及其制备方法和在制备治疗心脑血管类疾病的药物中的应用
CN114805104A (zh) * 2021-01-29 2022-07-29 南京宁丹新药技术有限公司 一类氨基水杨酸类衍生物及其用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002353845A1 (en) 2001-11-23 2003-06-10 Eli Lilly And Company Prodrugs of excitatory amino acids
CA2471642C (en) * 2001-12-27 2011-05-24 Taisho Pharmaceutical Co., Ltd. 6-fluorobicyclo[3.1.0]hexane derivatives
CA2530706C (en) 2003-06-26 2012-11-27 Taisho Pharmaceutical Co., Ltd. 2-amino-bicyclo[3.1.0] hexane-2,6-dicarboxylic ester derivative
US8642777B2 (en) 2009-11-19 2014-02-04 Taisho Pharmaceutical Co., Ltd Process for producing 3-alkoxy-2-amino-6-fluorobicyclo [3.1.0] hexane-2,6-dicarboxylic acid derivative and intermediate thereof
AR083845A1 (es) 2010-11-18 2013-03-27 Lilly Co Eli COMPUESTOS 3-FENILSULFANILMETIL-BICICLO[3.1.0]HEXANO 4-SUSTITUIDOS COMO ANTAGONISTAS DE mGluR2/3
CN103209954B (zh) * 2010-11-18 2015-09-02 伊莱利利公司 作为mGluR2/3拮抗剂的4-取代的-3-苄氧基-双环[3.1.0]己烷化合物
WO2013062680A1 (en) 2011-10-25 2013-05-02 Braincells, Inc. Novel compounds and compositions thereof for treating nervous system disorders
US9428483B2 (en) 2012-06-01 2016-08-30 Taisho Pharmaceutical Co., Ltd. Prodrug of fluorine-containing amino acid
US20150119345A1 (en) 2013-10-29 2015-04-30 Lumena Pharmaceuticals, Inc. Bile acid recycling inhibitors for treatment of gastrointestinal infections
EP3445743B1 (en) * 2016-04-18 2021-08-04 Taisho Pharmaceutical Co., Ltd. Prodrug of amino acid derivative

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